| MeSH term | MeSH ID | Detail |
|---|---|---|
| Catalepsy | D002375 | 30 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
| Bulimia | D002032 | 3 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Brain Damage, Chronic | D001925 | 6 associated lipids |
| Brain Concussion | D001924 | 5 associated lipids |
| Bradycardia | D001919 | 13 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zenor BN et al. | Endocrine and other responses to acute administration of cannabinoid compounds to non-stressed male calves. | 1999 | Life Sci. | pmid:10416818 |
| Hansen HS et al. | Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity. | 1999 | Lipids | pmid:10419193 |
| Kiss Z | Anandamide stimulates phospholipase D activity in PC12 cells but not in NIH 3T3 fibroblasts. | 1999 | FEBS Lett. | pmid:10214947 |
| Maccarrone M et al. | Anandamide activates human platelets through a pathway independent of the arachidonate cascade. | 1999 | FEBS Lett. | pmid:10214961 |
| Yang HY et al. | GC/MS analysis of anandamide and quantification of N-arachidonoylphosphatidylethanolamides in various brain regions, spinal cord, testis, and spleen of the rat. | 1999 | J. Neurochem. | pmid:10217273 |
| Raffa RB et al. | Differential cholera-toxin sensitivity of supraspinal antinociception induced by the cannabinoid agonists delta9-THC, WIN 55,212-2 and anandamide in mice. | 1999 | Neurosci. Lett. | pmid:10218903 |
| De Petrocellis L et al. | Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response. | 1999 | Neuroscience | pmid:10392859 |
| Williams CM and Kirkham TC | Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors. | 1999 | Psychopharmacology (Berl.) | pmid:10353436 |
| Fimiani C et al. | Morphine and anandamide stimulate intracellular calcium transients in human arterial endothelial cells: coupling to nitric oxide release. | 1999 | Cell. Signal. | pmid:10353693 |
| Ng EW et al. | Unique analogues of anandamide: arachidonyl ethers and carbamates and norarachidonyl carbamates and ureas. | 1999 | J. Med. Chem. | pmid:10354405 |
| Járai Z et al. | Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570211 |
| Sagan S et al. | Anandamide and WIN 55212-2 inhibit cyclic AMP formation through G-protein-coupled receptors distinct from CB1 cannabinoid receptors in cultured astrocytes. | 1999 | Eur. J. Neurosci. | pmid:10051770 |
| Kobayashi H et al. | Recent progress in the neurotoxicology of natural drugs associated with dependence or addiction, their endogenous agonists and receptors. | 1999 | J Toxicol Sci | pmid:10073332 |
| Bisogno T et al. | Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10079192 |
| Fleming I et al. | Inhibition of the production of endothelium-derived hyperpolarizing factor by cannabinoid receptor agonists. | 1999 | Br. J. Pharmacol. | pmid:10193775 |
| Hohmann AG et al. | Pre- and postsynaptic distribution of cannabinoid and mu opioid receptors in rat spinal cord. | 1999 | Brain Res. | pmid:10082879 |
| Wang J et al. | Stage-specific excitation of cannabinoid receptor exhibits differential effects on mouse embryonic development. | 1999 | Biol. Reprod. | pmid:10084956 |
| Ishioka N and Bukoski RD | A role for N-arachidonylethanolamine (anandamide) as the mediator of sensory nerve-dependent Ca2+-induced relaxation. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10087011 |
| Wiley JL | Cannabis: discrimination of "internal bliss"? | 1999 | Pharmacol. Biochem. Behav. | pmid:10515300 |
| Lu R et al. | Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C. | 1999 | Am. J. Physiol. | pmid:9950961 |
| González S et al. | Extrapyramidal and neuroendocrine effects of AM404, an inhibitor of the carrier-mediated transport of anandamide. | 1999 | Life Sci. | pmid:10447218 |
| Gebremedhin D et al. | Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current. | 1999 | Am. J. Physiol. | pmid:10362691 |
| Melck D et al. | Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10448105 |
| Bisogno T et al. | Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina. | 1999 | Arch. Biochem. Biophys. | pmid:10577359 |
| Lagalwar S et al. | Anandamides inhibit binding to the muscarinic acetylcholine receptor. | 1999 Aug-Oct | J. Mol. Neurosci. | pmid:10691292 |
| Levin M and Mercola M | Expression of connexin 30 in Xenopus embryos and its involvement in hatching gland function. | 2000 | Dev. Dyn. | pmid:10974676 |
| Morefield SI et al. | Drug evaluations using neuronal networks cultured on microelectrode arrays. | 2000 | Biosens Bioelectron | pmid:11219752 |
| Van den Bossche I and Vanheel B | Influence of cannabinoids on the delayed rectifier in freshly dissociated smooth muscle cells of the rat aorta. | 2000 | Br. J. Pharmacol. | pmid:10960073 |
| Boger DL et al. | Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10805767 |
| Smart D et al. | The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1). | 2000 | Br. J. Pharmacol. | pmid:10694225 |
| Melck D et al. | Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation. | 2000 | Endocrinology | pmid:10614630 |
| Sugiura T et al. | Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells. | 2000 | J. Biol. Chem. | pmid:10617657 |
| Zygmunt PM et al. | Anandamide - the other side of the coin. | 2000 | Trends Pharmacol. Sci. | pmid:10664604 |
| Jarrahian A et al. | Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter. | 2000 | J. Neurochem. | pmid:10820223 |
| Davis JB et al. | Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. | 2000 | Nature | pmid:10821274 |
| Zygmunt PM et al. | The anandamide transport inhibitor AM404 activates vanilloid receptors. | 2000 | Eur. J. Pharmacol. | pmid:10822052 |
| Di Marzo V et al. | Enhancement of anandamide formation in the limbic forebrain and reduction of endocannabinoid contents in the striatum of delta9-tetrahydrocannabinol-tolerant rats. | 2000 | J. Neurochem. | pmid:10737621 |
| Smart D and Jerman JC | Anandamide: an endogenous activator of the vanilloid receptor. | 2000 | Trends Pharmacol. Sci. | pmid:10740287 |
| Beltramo M et al. | Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitor. | 2000 | J. Neurosci. | pmid:10777802 |
| Gonsiorek W et al. | Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide. | 2000 | Mol. Pharmacol. | pmid:10779390 |
| Costa B and Colleoni M | Changes in rat brain energetic metabolism after exposure to anandamide or Delta(9)-tetrahydrocannabinol. | 2000 | Eur. J. Pharmacol. | pmid:10781666 |
| Sarker KP et al. | Anandamide induces apoptosis of PC-12 cells: involvement of superoxide and caspase-3. | 2000 | FEBS Lett. | pmid:10781801 |
| Hillard CJ | Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785538 |
| Burstein SH et al. | Oxidative metabolism of anandamide. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785540 |
| Di Marzo V et al. | Cannabimimetic fatty acid derivatives in cancer and inflammation. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785541 |
| Kunos G et al. | Cardiovascular effects of endocannabinoids--the plot thickens. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785543 |
| Maccarrone M et al. | Anandamide uptake by human endothelial cells and its regulation by nitric oxide. | 2000 | J. Biol. Chem. | pmid:10788462 |
| Yagen B and Burstein S | Novel and sensitive method for the detection of anandamide by the use of its dansyl derivative. | 2000 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10798298 |
| Zygmunt PM et al. | Differential actions of anandamide, potassium ions and endothelium-derived hyperpolarizing factor in guinea-pig basilar artery. | 2000 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10832608 |
| Gómez del Pulgar T et al. | The CB1 cannabinoid receptor is coupled to the activation of protein kinase B/Akt. | 2000 | Biochem. J. | pmid:10749665 |
| Fernandez-Patron C et al. | Vascular matrix metalloproteinase-2-dependent cleavage of calcitonin gene-related peptide promotes vasoconstriction. | 2000 | Circ. Res. | pmid:11029402 |
| Maccarrone M et al. | Anandamide and 2-arachidonoylglycerol inhibit fatty acid amide hydrolase by activating the lipoxygenase pathway of the arachidonate cascade. | 2000 | Biochem. Biophys. Res. Commun. | pmid:11095952 |
| Calignano A et al. | A role for the endogenous cannabinoid system in the peripheral control of pain initiation. | 2000 | Prog. Brain Res. | pmid:11098711 |
| Valk P et al. | Enhancement of erythropoietin-stimulated cell proliferation by Anandamide correlates with increased activation of the mitogen-activated protein kinases ERK1 and ERK2. | 2000 | Hematol. J. | pmid:11920199 |
| Di Marzo V et al. | Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain. | 2000 | J. Neurochem. | pmid:11080195 |
| Rubino T et al. | Loss of cannabinoid-stimulated guanosine 5'-O-(3-[(35)S]Thiotriphosphate) binding without receptor down-regulation in brain regions of anandamide-tolerant rats. | 2000 | J. Neurochem. | pmid:11080200 |
| Giuffrida A et al. | Elevated circulating levels of anandamide after administration of the transport inhibitor, AM404. | 2000 | Eur. J. Pharmacol. | pmid:11080522 |
| Rajan S et al. | TASK-3, a novel tandem pore domain acid-sensitive K+ channel. An extracellular histiding as pH sensor. | 2000 | J. Biol. Chem. | pmid:10747866 |
| Calignano A et al. | Bidirectional control of airway responsiveness by endogenous cannabinoids. | 2000 | Nature | pmid:11081515 |
| Reggio PH and Traore H | Conformational requirements for endocannabinoid interaction with the cannabinoid receptors, the anandamide transporter and fatty acid amidohydrolase. | 2000 | Chem. Phys. Lipids | pmid:11106780 |
| Howlett AC and Mukhopadhyay S | Cellular signal transduction by anandamide and 2-arachidonoylglycerol. | 2000 | Chem. Phys. Lipids | pmid:11106782 |
| Schmid HH | Pathways and mechanisms of N-acylethanolamine biosynthesis: can anandamide be generated selectively? | 2000 | Chem. Phys. Lipids | pmid:11106783 |
| Hillard CJ and Jarrahian A | The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes. | 2000 | Chem. Phys. Lipids | pmid:11106786 |
| Kunos G et al. | Endocannabinoids as cardiovascular modulators. | 2000 | Chem. Phys. Lipids | pmid:11106789 |
| Bisogno T et al. | N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo. | 2000 | Biochem. J. | pmid:11042139 |
| Wiley JL et al. | Influence of phenylmethylsulfonyl fluoride on anandamide brain levels and pharmacological effects. | 2000 | Life Sci. | pmid:10983852 |
| Stefano GB et al. | 2-arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1. | 2000 | Pharmacol. Res. | pmid:10987990 |
| Okamoto H et al. | Sphingosine 1-phosphate stimulates G(i)- and Rho-mediated vascular endothelial cell spreading and migration. | 2000 | Thromb. Res. | pmid:10942792 |
| Stefano GB | Endocannabinoid immune and vascular signaling. | 2000 | Acta Pharmacol. Sin. | pmid:11603279 |
| Martin BR et al. | Cannabinoid properties of methylfluorophosphonate analogs. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10945879 |
| Harris J et al. | Spinal anandamide inhibits nociceptive transmission via cannabinoid receptor activation in vivo. | 2000 | Neuroreport | pmid:10976969 |
| Oz M et al. | Endogenous cannabinoid anandamide directly inhibits voltage-dependent Ca(2+) fluxes in rabbit T-tubule membranes. | 2000 | Eur. J. Pharmacol. | pmid:10980258 |
| Klein TW et al. | The cannabinoid system and cytokine network. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:10998193 |
| Oliveira L et al. | Effects of some isoprostanes on the human umbilical artery in vitro. | 2000 | Br. J. Pharmacol. | pmid:10711349 |
| Fichera M et al. | A 3D-QSAR study on the structural requirements for binding to CB(1) and CB(2) cannabinoid receptors. | 2000 | J. Med. Chem. | pmid:10882356 |
| Spicuzza L et al. | Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves. | 2000 | Br. J. Pharmacol. | pmid:10928980 |
| Salzet M et al. | Comparative biology of the endocannabinoid system possible role in the immune response. | 2000 | Eur. J. Biochem. | pmid:10931174 |
| Hillard CJ | Endocannabinoids and vascular function. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10871291 |
| Song ZH and Zhong M | CB1 cannabinoid receptor-mediated cell migration. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10871313 |
| Tytgat J et al. | Cannabinoid mimics in chocolate utilized as an argument in court. | 2000 | Int. J. Legal Med. | pmid:10876983 |
| Maccarrone M et al. | Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors. | 2000 | J. Biol. Chem. | pmid:10913156 |
| Andersson M et al. | Neurotoxicity of glutamate in chick telencephalon neurons: reduction of toxicity by preincubation with carbachol, but not by the endogenous fatty acid amides anandamide and palmitoylethanolamide. | 2000 | Arch. Toxicol. | pmid:10877002 |
| Maccarrone M et al. | Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage. | 2000 | Lancet | pmid:10776746 |
| Maccarrone M et al. | Human mast cells take up and hydrolyze anandamide under the control of 5-lipoxygenase and do not express cannabinoid receptors. | 2000 | FEBS Lett. | pmid:10692582 |
| Houser SJ et al. | Dynorphin B and spinal analgesia: induction of antinociception by the cannabinoids CP55,940, Delta(9)-THC and anandamide. | 2000 | Brain Res. | pmid:10700588 |
| Lay L et al. | Pharmacological characterisation of cannabinoid CB(1) receptors in the rat and mouse. | 2000 | Eur. J. Pharmacol. | pmid:10720647 |
| Tiger G et al. | Pharmacological properties of rat brain fatty acid amidohydrolase in different subcellular fractions using palmitoylethanolamide as substrate. | 2000 | Biochem. Pharmacol. | pmid:10677581 |
| Schmid PC et al. | A sensitive endocannabinoid assay. The simultaneous analysis of N-acylethanolamines and 2-monoacylglycerols. | 2000 | Chem. Phys. Lipids | pmid:10669310 |
| Griffin G et al. | Cloning and pharmacological characterization of the rat CB(2) cannabinoid receptor. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688601 |
| Rakhshan F et al. | Carrier-mediated uptake of the endogenous cannabinoid anandamide in RBL-2H3 cells. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688610 |
| De Petrocellis L et al. | Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid receptor: inhibitors of anandamide uptake with negligible capsaicin-like activity. | 2000 | FEBS Lett. | pmid:11033355 |
| Di Marzo V et al. | Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide. | 2000 | Eur. J. Pharmacol. | pmid:11040343 |
| Arai Y et al. | Sensitive determination of anandamide in rat brain utilizing a coupled-column HPLC with fluorimetric detection. | 2000 | Biomed. Chromatogr. | pmid:10694706 |
| Szallasi A and Di Marzo V | New perspectives on enigmatic vanilloid receptors. | 2000 | Trends Neurosci. | pmid:11006466 |
| González S et al. | Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10733937 |
| Muthian S et al. | Synthesis and characterization of a fluorescent substrate for the N-arachidonoylethanolamine (anandamide) transmembrane carrier. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10734181 |
| Wang Y et al. | Polymyxin B binds to anandamide and inhibits its cytotoxic effect. | 2000 | FEBS Lett. | pmid:10734225 |
| Bannerman P et al. | Early migratory rat neural crest cells express functional gap junctions: evidence that neural crest cell survival requires gap junction function. | 2000 | J. Neurosci. Res. | pmid:10972957 |
| Di Marzo V et al. | Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease. | 2000 | FASEB J. | pmid:10877836 |
| Markey SP et al. | Base- and acid-catalyzed interconversions of O-acyl- and N-acyl-ethanolamines: a cautionary note for lipid analyses. | 2000 | J. Lipid Res. | pmid:10744787 |