| MeSH term | MeSH ID | Detail |
|---|---|---|
| Catalepsy | D002375 | 30 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
| Bulimia | D002032 | 3 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Brain Damage, Chronic | D001925 | 6 associated lipids |
| Brain Concussion | D001924 | 5 associated lipids |
| Bradycardia | D001919 | 13 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jones BR et al. | Surrogate matrix and surrogate analyte approaches for definitive quantitation of endogenous biomolecules. | 2012 | Bioanalysis | pmid:23088461 |
| Bisogno T et al. | The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9344854 |
| Bornheim LM et al. | The effect of cannabidiol on mouse hepatic microsomal cytochrome P450-dependent anandamide metabolism. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8267610 |
| Catanzaro G et al. | Anandamide increases swelling and reduces calcium sensitivity of mitochondria. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19679102 |
| Bisogno T et al. | Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9703957 |
| Bisogno T et al. | Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10079192 |
| Soltys J et al. | Regulation of neural progenitor cell fate by anandamide. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20691161 |
| Sugiura T et al. | Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8573114 |
| Kozono S et al. | Involvement of the endocannabinoid system in periodontal healing. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20233580 |
| Sugiura T et al. | 2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7575630 |
| Chen J et al. | Finding of endocannabinoids in human eye tissues: implications for glaucoma. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15823551 |
| Maccarrone M et al. | Anandamide and 2-arachidonoylglycerol inhibit fatty acid amide hydrolase by activating the lipoxygenase pathway of the arachidonate cascade. | 2000 | Biochem. Biophys. Res. Commun. | pmid:11095952 |
| Di Marzo V et al. | Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8858137 |
| Sugiura T et al. | 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma x glioma hybrid NG108-15 cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8954083 |
| Kurahashi Y et al. | Reversible hydrolysis and synthesis of anandamide demonstrated by recombinant rat fatty-acid amide hydrolase. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9299394 |
| Wenger T et al. | Arachidonyl ethanolamide (anandamide) activates the parvocellular part of hypothalamic paraventricular nucleus. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9299434 |
| De Petrocellis L et al. | Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9070224 |
| Deutsch DG et al. | Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9070252 |
| Melck D et al. | Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10448105 |
| Di Marzo V et al. | Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor "hybrid" ligands. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11181068 |
| van Zadelhoff G et al. | With anandamide as substrate plant 5-lipoxygenases behave like 11-lipoxygenases. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9675081 |
| Randall MD et al. | An endogenous cannabinoid as an endothelium-derived vasorelaxant. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8954092 |
| González S et al. | Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10733937 |
| Wenger T et al. | The central cannabinoid receptor inactivation suppresses endocrine reproductive functions. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11394887 |
| Athanasiou A et al. | Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17931597 |
| Ferrer B et al. | Regulation of brain anandamide by acute administration of ethanol. | 2007 | Biochem. J. | pmid:17302558 |
| Wisnoskey BJ et al. | Activation of vanilloid receptor type I in the endoplasmic reticulum fails to activate store-operated Ca2+ entry. | 2003 | Biochem. J. | pmid:12608892 |
| Di Marzo V et al. | Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. | 1996 | Biochem. J. | pmid:8670178 |
| Gómez del Pulgar T et al. | The CB1 cannabinoid receptor is coupled to the activation of protein kinase B/Akt. | 2000 | Biochem. J. | pmid:10749665 |
| Bisogno T et al. | N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo. | 2000 | Biochem. J. | pmid:11042139 |
| Sun YX et al. | Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D. | 2004 | Biochem. J. | pmid:14998370 |
| Ligresti A et al. | Further evidence for the existence of a specific process for the membrane transport of anandamide. | 2004 | Biochem. J. | pmid:14969584 |
| Bisogno T et al. | Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. | 1997 | Biochem. J. | pmid:9065792 |
| Di Marzo V et al. | Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells. | 2001 | Biochem. J. | pmid:11485574 |
| Di Marzo V et al. | The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide. | 1998 | Biochem. J. | pmid:9512456 |
| Maccarrone M et al. | Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells. | 2002 | Biochem. J. | pmid:12010121 |
| Correa F et al. | Anandamide inhibits IL-12p40 production by acting on the promoter repressor element GA-12: possible involvement of the COX-2 metabolite prostamide E(2). | 2008 | Biochem. J. | pmid:17961121 |
| Bornheim LM et al. | Microsomal cytochrome P450-mediated liver and brain anandamide metabolism. | 1995 | Biochem. Pharmacol. | pmid:7669071 |
| Childers SR et al. | Effects of anandamide on cannabinoid receptors in rat brain membranes. | 1994 | Biochem. Pharmacol. | pmid:8129747 |
| Fowler CJ et al. | Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid. | 2003 | Biochem. Pharmacol. | pmid:12948856 |
| Hansen HS and Diep TA | N-acylethanolamines, anandamide and food intake. | 2009 | Biochem. Pharmacol. | pmid:19413995 |
| Ortar G et al. | Novel selective and metabolically stable inhibitors of anandamide cellular uptake. | 2003 | Biochem. Pharmacol. | pmid:12732359 |
| Mechoulam R et al. | Search for endogenous ligands of the cannabinoid receptor. | 1994 | Biochem. Pharmacol. | pmid:7980618 |
| Goparaju SK et al. | Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors. | 1999 | Biochem. Pharmacol. | pmid:9933030 |
| Burstein SH et al. | Regulation of anandamide tissue levels by N-arachidonylglycine. | 2002 | Biochem. Pharmacol. | pmid:12234618 |
| Burstein SH and Hunter SA | Stimulation of anandamide biosynthesis in N-18TG2 neuroblastoma cells by delta 9-tetrahydrocannabinol (THC). | 1995 | Biochem. Pharmacol. | pmid:7702643 |
| Deutsch DG and Chin SA | Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. | 1993 | Biochem. Pharmacol. | pmid:8373432 |
| Thumser AE et al. | A fluorescence displacement assay for the measurement of arachidonoyl ethanolamide (anandamide) and oleoyl amide (octadecenoamide) hydrolysis. | 1997 | Biochem. Pharmacol. | pmid:9065749 |
| Lo YK et al. | Effect of arvanil (N-arachidonoyl-vanillyl-amine), a nonpungent anandamide-capsaicin hybrid, on ion currents in NG108-15 neuronal cells. | 2003 | Biochem. Pharmacol. | pmid:12566085 |
| Lanzafame AA et al. | Effects of anandamide on the binding and signaling properties of M1 muscarinic acetylcholine receptors. | 2004 | Biochem. Pharmacol. | pmid:15498511 |