Köfalvi A et al. |
Anandamide and NADA bi-directionally modulate presynaptic Ca2+ levels and transmitter release in the hippocampus. |
2007 |
Br. J. Pharmacol. |
pmid:17435795
|
Roberts LA et al. |
Anandamide is a partial agonist at native vanilloid receptors in acutely isolated mouse trigeminal sensory neurons. |
2002 |
Br. J. Pharmacol. |
pmid:12359623
|
White R et al. |
Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. |
2001 |
Br. J. Pharmacol. |
pmid:11606334
|
Ghasemi M et al. |
Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats. |
2007 |
Br. J. Pharmacol. |
pmid:17486141
|
Fraga D et al. |
Endogenous cannabinoids induce fever through the activation of CB1 receptors. |
2009 |
Br. J. Pharmacol. |
pmid:19681872
|
O'Sullivan SE et al. |
Heterogeneity in the mechanisms of vasorelaxation to anandamide in resistance and conduit rat mesenteric arteries. |
2004 |
Br. J. Pharmacol. |
pmid:15148250
|
De Petrocellis L et al. |
A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons. |
2012 |
Br. J. Pharmacol. |
pmid:22861649
|
Gamaleddin I et al. |
The selective anandamide transport inhibitor VDM11 attenuates reinstatement of nicotine seeking behaviour, but does not affect nicotine intake. |
2011 |
Br. J. Pharmacol. |
pmid:21501143
|
Jamshidi N and Taylor DA |
Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. |
2001 |
Br. J. Pharmacol. |
pmid:11704633
|
Shouman B et al. |
Endocannabinoids potently protect the newborn brain against AMPA-kainate receptor-mediated excitotoxic damage. |
2006 |
Br. J. Pharmacol. |
pmid:16682966
|
O'Sullivan SE et al. |
The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide. |
2005 |
Br. J. Pharmacol. |
pmid:15821751
|
Guindon J et al. |
Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. |
2011 |
Br. J. Pharmacol. |
pmid:21198549
|
Craib SJ et al. |
A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus. |
2001 |
Br. J. Pharmacol. |
pmid:11522594
|
White R and Hiley CR |
A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. |
1997 |
Br. J. Pharmacol. |
pmid:9422801
|
Zygmunt PM et al. |
Studies on the effects of anandamide in rat hepatic artery. |
1997 |
Br. J. Pharmacol. |
pmid:9422814
|
Lever IJ and Malcangio M |
CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord. |
2002 |
Br. J. Pharmacol. |
pmid:11786475
|
Gardiner SM et al. |
Complex regional haemodynamic effects of anandamide in conscious rats. |
2002 |
Br. J. Pharmacol. |
pmid:11959791
|
Pei R et al. |
Low-fat yogurt consumption reduces biomarkers of chronic inflammation and inhibits markers of endotoxin exposure in healthy premenopausal women: a randomised controlled trial. |
2017 |
Br. J. Nutr. |
pmid:29179781
|
Morgan CJ et al. |
Cerebrospinal fluid anandamide levels, cannabis use and psychotic-like symptoms. |
2013 |
Br J Psychiatry |
pmid:23580381
|
Koethe D et al. |
Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. |
2009 |
Br J Psychiatry |
pmid:19336792
|
Jarzimski C et al. |
Changes of blood endocannabinoids during anaesthesia: a special case for fatty acid amide hydrolase inhibition by propofol? |
2012 |
Br J Clin Pharmacol |
pmid:22242687
|
Lam PM et al. |
Characterization and comparison of recombinant human and rat TRPV1 receptors: effects of exo- and endocannabinoids. |
2005 |
Br J Anaesth |
pmid:15722382
|
Davies JW et al. |
Pharmacology of capsaicin-, anandamide-, and N-arachidonoyl-dopamine-evoked cell death in a homogeneous transient receptor potential vanilloid subtype 1 receptor population. |
2010 |
Br J Anaesth |
pmid:20354008
|
Weis F et al. |
Effect of anaesthesia and cardiopulmonary bypass on blood endocannabinoid concentrations during cardiac surgery. |
2010 |
Br J Anaesth |
pmid:20525978
|
Jerman JC et al. |
Comparison of effects of anandamide at recombinant and endogenous rat vanilloid receptors. |
2002 |
Br J Anaesth |
pmid:12453933
|
Rossi F et al. |
The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption. |
2009 |
Bone |
pmid:19059369
|
Gesell FK et al. |
Alterations of endocannabinoids in cerebrospinal fluid of dogs with epileptic seizure disorder. |
2013 |
BMC Vet. Res. |
pmid:24370333
|
Kumar S |
Computational identification and binding analysis of orphan human cytochrome P450 4X1 enzyme with substrates. |
2015 |
BMC Res Notes |
pmid:25595103
|
Cipriano M et al. |
The influence of monoacylglycerol lipase inhibition upon the expression of epidermal growth factor receptor in human PC-3 prostate cancer cells. |
2014 |
BMC Res Notes |
pmid:25012825
|
Hayase T |
Differential effects of TRPV1 receptor ligands against nicotine-induced depression-like behaviors. |
2011 |
BMC Pharmacol. |
pmid:21767384
|
Neelamegan D et al. |
Identification and recombinant expression of anandamide hydrolyzing enzyme from Dictyostelium discoideum. |
2012 |
BMC Microbiol. |
pmid:22730904
|
Bradshaw HB et al. |
The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways. |
2009 |
BMC Biochem. |
pmid:19460156
|
Maccarrone M et al. |
Estrogen stimulates arachidonoylethanolamide release from human endothelial cells and platelet activation. |
2002 |
Blood |
pmid:12393387
|
Valk P et al. |
Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells. |
1997 |
Blood |
pmid:9269762
|
Ghasemi M et al. |
Anandamide improves the impaired nitric oxide-mediated neurogenic relaxation of the corpus cavernosum in diabetic rats: involvement of cannabinoid CB1 and vanilloid VR1 receptors. |
2007 |
BJU Int. |
pmid:17850365
|
Nallendran V et al. |
The plasma levels of the endocannabinoid, anandamide, increase with the induction of labour. |
2010 |
BJOG |
pmid:20406230
|
Psychoyos D et al. |
Cannabinoid receptor 1 signaling in embryo neurodevelopment. |
2012 |
Birth Defects Res. B Dev. Reprod. Toxicol. |
pmid:22311661
|
Morefield SI et al. |
Drug evaluations using neuronal networks cultured on microelectrode arrays. |
2000 |
Biosens Bioelectron |
pmid:11219752
|
Boger DL et al. |
alpha-Keto heterocycle inhibitors of fatty acid amide hydrolase: carbonyl group modification and alpha-substitution. |
2001 |
Bioorg. Med. Chem. Lett. |
pmid:11412972
|
Sit SY et al. |
Novel inhibitors of fatty acid amide hydrolase. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17459705
|
El Fangour S et al. |
Hemisynthesis and preliminary evaluation of novel endocannabinoid analogues. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12781177
|
Parkkari T et al. |
Synthesis and CB1 receptor activities of novel arachidonyl alcohol derivatives. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15149681
|
Segall Y et al. |
Arachidonylsulfonyl derivatives as cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12951114
|
Ortar G et al. |
New tetrazole-based selective anandamide uptake inhibitors. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18424134
|
Balas L et al. |
Synthesis of a potential photoactivatable anandamide analog. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16682198
|
Yao F et al. |
Development of novel tail-modified anandamide analogs. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18723350
|
Urbani P et al. |
New metabolically stable fatty acid amide ligands of cannabinoid receptors: Synthesis and receptor affinity studies. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16213718
|
Aneetha H et al. |
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19013794
|
Brizzi A et al. |
Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors. |
2007 |
Bioorg. Med. Chem. |
pmid:17561406
|
Duarte CD et al. |
Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors. |
2007 |
Bioorg. Med. Chem. |
pmid:17275312
|
Di Marzo V et al. |
The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region. |
2004 |
Bioorg. Med. Chem. |
pmid:15351399
|
Vandevoorde S et al. |
N-Morpholino- and N-diethyl-analogues of palmitoylethanolamide increase the sensitivity of transfected human vanilloid receptors to activation by anandamide without affecting fatty acid amidohydrolase activity. |
2003 |
Bioorg. Med. Chem. |
pmid:12614867
|
Osman NA et al. |
Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands. |
2010 |
Bioorg. Med. Chem. |
pmid:21074998
|
Bourne C et al. |
Novel, potent THC/anandamide (hybrid) analogs. |
2007 |
Bioorg. Med. Chem. |
pmid:17827022
|
Parkkari T et al. |
Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide. |
2006 |
Bioorg. Med. Chem. |
pmid:16644227
|
Kono M et al. |
Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors. |
2014 |
Bioorg. Med. Chem. |
pmid:24440478
|
Ferreri C et al. |
Synthesis of all-trans anandamide: a substrate for fatty acid amide hydrolase with dual effects on rabbit platelet activation. |
2008 |
Bioorg. Med. Chem. |
pmid:18782671
|
Wyffels L et al. |
Radiosynthesis, in vitro and in vivo evaluation of 123I-labeled anandamide analogues for mapping brain FAAH. |
2009 |
Bioorg. Med. Chem. |
pmid:19054678
|
Koga D et al. |
High-performance liquid chromatography and fluorometric detection of arachidonylethanolamide (anandamide) and its analogues, derivatized with 4-(N-chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulp honyl-2,1 ,3- benzoxadiazole (DBD-COCl). |
1995 Jan-Feb |
Biomed. Chromatogr. |
pmid:7734936
|
Schmidt A et al. |
Determination of the endocannabinoid anandamide in human plasma by high-performance liquid chromatography. |
2006 |
Biomed. Chromatogr. |
pmid:16189813
|
Arai Y et al. |
Sensitive determination of anandamide in rat brain utilizing a coupled-column HPLC with fluorimetric detection. |
2000 |
Biomed. Chromatogr. |
pmid:10694706
|
Wang X et al. |
Circulating Endocannabinoids and Insulin Resistance in Patients with Obstructive Sleep Apnea. |
2016 |
Biomed Res Int |
pmid:26904688
|
Spaziano G et al. |
Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS. |
2015 |
Biomed Res Int |
pmid:25866824
|
Malek N et al. |
Alterations in the anandamide metabolism in the development of neuropathic pain. |
2014 |
Biomed Res Int |
pmid:25276812
|
Paria BC et al. |
Fatty-acid amide hydrolase is expressed in the mouse uterus and embryo during the periimplantation period. |
1999 |
Biol. Reprod. |
pmid:10208977
|
Wang J et al. |
Stage-specific excitation of cannabinoid receptor exhibits differential effects on mouse embryonic development. |
1999 |
Biol. Reprod. |
pmid:10084956
|
Cobellis G et al. |
Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells. |
2006 |
Biol. Reprod. |
pmid:16611862
|
Yang ZM et al. |
Activation of brain-type cannabinoid receptors interferes with preimplantation mouse embryo development. |
1996 |
Biol. Reprod. |
pmid:8879486
|
Sun X et al. |
Genetic loss of Faah compromises male fertility in mice. |
2009 |
Biol. Reprod. |
pmid:18987328
|
Paria BC et al. |
Effects of cannabinoids on preimplantation mouse embryo development and implantation are mediated by brain-type cannabinoid receptors. |
1998 |
Biol. Reprod. |
pmid:9623610
|
Schuel H and Burkman LJ |
A tale of two cells: endocannabinoid-signaling regulates functions of neurons and sperm. |
2005 |
Biol. Reprod. |
pmid:16120829
|
Demers CH et al. |
Interactions Between Anandamide and Corticotropin-Releasing Factor Signaling Modulate Human Amygdala Function and Risk for Anxiety Disorders: An Imaging Genetics Strategy for Modeling Molecular Interactions. |
2016 |
Biol. Psychiatry |
pmid:26923505
|
Lu HC and Mackie K |
An Introduction to the Endogenous Cannabinoid System. |
2016 |
Biol. Psychiatry |
pmid:26698193
|
Saravia R et al. |
CB Cannabinoid Receptors Mediate Cognitive Deficits and Structural Plasticity Changes During Nicotine Withdrawal. |
2017 |
Biol. Psychiatry |
pmid:27737762
|
Busquets-Garcia A et al. |
Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses. |
2011 |
Biol. Psychiatry |
pmid:21684528
|
Tzavara ET et al. |
Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications. |
2006 |
Biol. Psychiatry |
pmid:16199010
|
Justinova Z et al. |
Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates. |
2008 |
Biol. Psychiatry |
pmid:18814866
|
Watanabe K et al. |
Pharmacological effects in mice of anandamide and its related fatty acid ethanolamides, and enhancement of cataleptogenic effect of anandamide by phenylmethylsulfonyl fluoride. |
1999 |
Biol. Pharm. Bull. |
pmid:10328555
|
Shiraishi T et al. |
The presence of ceramidase activity in liver nuclear membrane. |
2003 |
Biol. Pharm. Bull. |
pmid:12808285
|
Kimura T et al. |
Anandamide, an endogenous cannabinoid receptor ligand, also interacts with 5-hydroxytryptamine (5-HT) receptor. |
1998 |
Biol. Pharm. Bull. |
pmid:9556149
|
Zolese G et al. |
Effect of acylethanolamides on lipid peroxidation and paraoxonase activity. |
2008 |
Biofactors |
pmid:19478424
|
Grambow E et al. |
Differential effects of endogenous, phyto and synthetic cannabinoids on thrombogenesis and platelet activity. |
2016 |
Biofactors |
pmid:27151562
|
Almada M et al. |
Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release. |
2016 |
Biofactors |
pmid:26945481
|
Lipina C et al. |
New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance. |
2012 |
Bioessays |
pmid:22674489
|
Karava V et al. |
Anandamide metabolism by Tetrahymena pyriformis in vitro. Characterization and identification of a 66 kDa fatty acid amidohydrolase. |
2005 |
Biochimie |
pmid:15951097
|
Spoto B et al. |
Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2-arachidonoylglycerol. |
2006 |
Biochimie |
pmid:16949718
|
Romani R et al. |
Anandamide and its congeners inhibit human plasma butyrylcholinesterase. Possible new roles for these endocannabinoids? |
2011 |
Biochimie |
pmid:21664223
|
Hillard CJ et al. |
Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain. |
1995 |
Biochim. Biophys. Acta |
pmid:7647100
|
Jia Y and Lee LY |
Role of TRPV receptors in respiratory diseases. |
2007 |
Biochim. Biophys. Acta |
pmid:17346945
|
Katayama K et al. |
Equilibrium in the hydrolysis and synthesis of cannabimimetic anandamide demonstrated by a purified enzyme. |
1999 |
Biochim. Biophys. Acta |
pmid:10521704
|
Hampson AJ et al. |
Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor. |
1995 |
Biochim. Biophys. Acta |
pmid:7488638
|
Sun YX et al. |
Involvement of N-acylethanolamine-hydrolyzing acid amidase in the degradation of anandamide and other N-acylethanolamines in macrophages. |
2005 |
Biochim. Biophys. Acta |
pmid:16154384
|
Urquhart P et al. |
Endocannabinoids and their oxygenation by cyclo-oxygenases, lipoxygenases and other oxygenases. |
2015 |
Biochim. Biophys. Acta |
pmid:25543004
|
Leishman E et al. |
Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain. |
2016 |
Biochim. Biophys. Acta |
pmid:26956082
|
Bueb JL et al. |
Receptor-independent effects of natural cannabinoids in rat peritoneal mast cells in vitro. |
2001 |
Biochim. Biophys. Acta |
pmid:11336796
|
Tsuboi K et al. |
Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways. |
2011 |
Biochim. Biophys. Acta |
pmid:21801852
|
Bisogno T et al. |
Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus. |
1997 |
Biochim. Biophys. Acta |
pmid:9150253
|
Almada M et al. |
Anandamide and decidual remodelling: COX-2 oxidative metabolism as a key regulator. |
2015 |
Biochim. Biophys. Acta |
pmid:26335727
|
Hansen HS et al. |
Glutamate stimulates the formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cortical neurons in culture. |
1995 |
Biochim. Biophys. Acta |
pmid:7548201
|
Ueda N et al. |
Lipoxygenase-catalyzed oxygenation of arachidonylethanolamide, a cannabinoid receptor agonist. |
1995 |
Biochim. Biophys. Acta |
pmid:7827116
|