Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Vascular System Injuries D057772 2 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Pregnancy, Ectopic D011271 5 associated lipids
Ocular Hypotension D015814 2 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Impotence, Vasculogenic D018783 4 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Somatosensory Disorders D020886 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Thomas EA et al. Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system. 1997 J. Neurosci. Res. pmid:9452020
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Mechoulam R et al. Anandamide may mediate sleep induction. 1997 Nature pmid:9288961
Wiley JL et al. Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. 1997 Pharmacol. Biochem. Behav. pmid:9408225
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Deutsch DG et al. Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor. 1997 Biochem. Biophys. Res. Commun. pmid:9070252
Lake KD et al. Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. 1997 Hypertension pmid:9149688
Bisogno T et al. Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus. 1997 Biochim. Biophys. Acta pmid:9150253
Berdyshev EV et al. Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells. 1997 Eur. J. Pharmacol. pmid:9253958
Soderstrom K et al. Discovery of novel cannabinoid receptor ligands from diverse marine organisms. 1997 Adv. Exp. Med. Biol. pmid:9561107
Fowler CJ et al. Ibuprofen inhibits rat brain deamidation of anandamide at pharmacologically relevant concentrations. Mode of inhibition and structure-activity relationship. 1997 J. Pharmacol. Exp. Ther. pmid:9353392
Stark S et al. Binding of aminoalkylindoles to noncannabinoid binding sites in NG108-15 cells. 1997 Cell. Mol. Neurobiol. pmid:9353590
van der Stelt M et al. The effect of hydroxylation of linoleoyl amides on their cannabinomimetic properties. 1997 FEBS Lett. pmid:9357990
Beltramo M et al. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. 1997 Science pmid:9262477
Valk P et al. Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells. 1997 Blood pmid:9269762
Twitchell W et al. Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons. 1997 J. Neurophysiol. pmid:9242259
Matsuda S et al. Metabolism of anandamide, an endogenous cannabinoid receptor ligand, in porcine ocular tissues. 1997 Exp. Eye Res. pmid:9245900
Wagner JA et al. Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. 1997 Nature pmid:9394002
Burkey RT and Nation JR (R)-methanandamide, but not anandamide, substitutes for delta 9-THC in a drug-discrimination procedure. 1997 Exp Clin Psychopharmacol pmid:9260067
Mikawa Y et al. Ocular activity of topically administered anandamide in the rabbit. 1997 Jul-Aug Jpn. J. Ophthalmol. pmid:9304433
Fulton D and Quilley J Evidence against anandamide as the hyperpolarizing factor mediating the nitric oxide-independent coronary vasodilator effect of bradykinin in the rat. 1998 J. Pharmacol. Exp. Ther. pmid:9732371
Welch SP et al. Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A. 1998 J. Pharmacol. Exp. Ther. pmid:9732392
Fields HL and Meng ID Watching the pot boil. 1998 Nat. Med. pmid:9734389
Pate DW et al. Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits. 1998 Life Sci. pmid:9851310
Molina-Holgado F et al. The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway. 1998 FEBS Lett. pmid:9738948
Stefano GB et al. Anandamide amidase inhibition enhances anandamide-stimulated nitric oxide release in invertebrate neural tissues. 1998 Brain Res. pmid:9630717
Schmid PC et al. Alternative pathways of anandamide biosynthesis in rat testes. 1998 Chem. Phys. Lipids pmid:9631536
Varga K et al. Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. 1998 FASEB J. pmid:9707176
Mallet PE and Beninger RJ Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. 1998 Life Sci. pmid:9651110