Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Overweight D050177 11 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Orthostatic Intolerance D054971 1 associated lipids
Vascular System Injuries D057772 2 associated lipids
Acute Pain D059787 3 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Kreitzer AC and Regehr WG Retrograde signaling by endocannabinoids. 2002 Curr. Opin. Neurobiol. pmid:12049940
Mechoulam R Discovery of endocannabinoids and some random thoughts on their possible roles in neuroprotection and aggression. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052029
Sugiura T et al. Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052034
Fowler CJ and Jacobsson SO Cellular transport of anandamide, 2-arachidonoylglycerol and palmitoylethanolamide--targets for drug development? 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052035
Deutsch DG et al. The fatty acid amide hydrolase (FAAH). 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052036
Fride E Endocannabinoids in the central nervous system--an overview. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052038
Pinto L et al. Endocannabinoids and the gut. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052047
Högestätt ED and Zygmunt PM Cardiovascular pharmacology of anandamide. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052048
Di Marzo V et al. Anandamide receptors. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052051
van der Stelt M et al. Acute neuronal injury, excitotoxicity, and the endocannabinoid system. 2002 Oct-Dec Mol. Neurobiol. pmid:12428763
Jones S and Howl J Cannabinoid receptor systems: therapeutic targets for tumour intervention. 2003 Expert Opin. Ther. Targets pmid:14640910
Zoratti C et al. Anandamide initiates Ca(2+) signaling via CB2 receptor linked to phospholipase C in calf pulmonary endothelial cells. 2003 Br. J. Pharmacol. pmid:14645143
Wang H et al. Differential G protein-coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:14645706
Gurney AM et al. Two-pore domain K channel, TASK-1, in pulmonary artery smooth muscle cells. 2003 Circ. Res. pmid:14551239
Biswas KK et al. Membrane cholesterol but not putative receptors mediates anandamide-induced hepatocyte apoptosis. 2003 Hepatology pmid:14578855
Vandevoorde S et al. Esters, retroesters, and a retroamide of palmitic acid: pool for the first selective inhibitors of N-palmitoylethanolamine-selective acid amidase. 2003 J. Med. Chem. pmid:14521402
Li J et al. Anandamide-induced depressor effect in spontaneously hypertensive rats: role of the vanilloid receptor. 2003 Hypertension pmid:12623992
Vásquez C et al. Effects of cannabinoids on endogenous K+ and Ca2+ currents in HEK293 cells. 2003 Can. J. Physiol. Pharmacol. pmid:12774849
Fowler CJ et al. Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid. 2003 Biochem. Pharmacol. pmid:12948856
Shiraishi T et al. The presence of ceramidase activity in liver nuclear membrane. 2003 Biol. Pharm. Bull. pmid:12808285
Klegeris A et al. Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor. 2003 Br. J. Pharmacol. pmid:12813001
Wilson SJ et al. A high-throughput-compatible assay for determining the activity of fatty acid amide hydrolase. 2003 Anal. Biochem. pmid:12814631
Maccarrone M et al. The endocannabinoid system in human keratinocytes. Evidence that anandamide inhibits epidermal differentiation through CB1 receptor-dependent inhibition of protein kinase C, activation protein-1, and transglutaminase. 2003 J. Biol. Chem. pmid:12815050
Obata T et al. Simultaneous determination of endocannabinoids (arachidonylethanolamide and 2-arachidonylglycerol) and isoprostane (8-epiprostaglandin F2alpha) by gas chromatography-mass spectrometry-selected ion monitoring for medical samples. 2003 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:12829006
Nicholson RA et al. Sodium channel inhibition by anandamide and synthetic cannabimimetics in brain. 2003 Brain Res. pmid:12834914
Pearlman RJ et al. Arachidonic acid and anandamide have opposite modulatory actions at the glycine transporter, GLYT1a. 2003 J. Neurochem. pmid:12558979
Perrier JF et al. 5-HT1A receptors increase excitability of spinal motoneurons by inhibiting a TASK-1-like K+ current in the adult turtle. 2003 J. Physiol. (Lond.) pmid:12626670
Maccarrone M et al. Progesterone activates fatty acid amide hydrolase (FAAH) promoter in human T lymphocytes through the transcription factor Ikaros. Evidence for a synergistic effect of leptin. 2003 J. Biol. Chem. pmid:12799380
Kasai HF et al. Analyses of anandamide and endocannabinoid-like compounds using collision-induced dissociation in fast atom bombardment ionization-mass spectrometry and gas chromatography/chemical ionization-mass spectrometry. 2003 Anal Sci pmid:14696920
Gaetani S et al. Anandamide hydrolysis: a new target for anti-anxiety drugs? 2003 Trends Mol Med pmid:14604824
Maccarrone M et al. Levodopa treatment reverses endocannabinoid system abnormalities in experimental parkinsonism. 2003 J. Neurochem. pmid:12716433
Marinelli S et al. Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors. 2003 J. Neurosci. pmid:12716921
McVey DC et al. Endocannabinoids induce ileitis in rats via the capsaicin receptor (VR1). 2003 J. Pharmacol. Exp. Ther. pmid:12538826
Scorticati C et al. The effect of anandamide on prolactin secretion is modulated by estrogen. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:12578974
Ahluwalia J et al. Activation of capsaicin-sensitive primary sensory neurones induces anandamide production and release. 2003 J. Neurochem. pmid:12558978
Sancho R et al. Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway. 2003 Mol. Pharmacol. pmid:12527815
Jennings EA et al. The actions of anandamide on rat superficial medullary dorsal horn neurons in vitro. 2003 J. Physiol. (Lond.) pmid:12562891
Dogulu FH et al. Intra-arterial simultaneous administration of anandamide attenuates endothelin-1 induced vasospasm in rabbit basilar arteries. 2003 Acta Neurochir (Wien) pmid:12910401
Fasia L et al. Uptake and metabolism of [3H]anandamide by rabbit platelets. Lack of transporter? 2003 Eur. J. Biochem. pmid:12919314
Sarker KP and Maruyama I Anandamide induces cell death independently of cannabinoid receptors or vanilloid receptor 1: possible involvement of lipid rafts. 2003 Cell. Mol. Life Sci. pmid:12861385
Bojesen IN and Hansen HS Binding of anandamide to bovine serum albumin. 2003 J. Lipid Res. pmid:12837852
Patel S et al. The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase. 2003 Br. J. Pharmacol. pmid:12839875
Watanabe H et al. Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. 2003 Nature pmid:12879072
Kozak KR et al. Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid anandamide. 2003 Biochemistry pmid:12885237
Mechoulam R and Lichtman AH Neuroscience. Stout guards of the central nervous system. 2003 Science pmid:14526067
Marsicano G et al. CB1 cannabinoid receptors and on-demand defense against excitotoxicity. 2003 Science pmid:14526074
Steffens M et al. Quantitative measurement of depolarization-induced anandamide release in human and rat neocortex. 2003 Naunyn Schmiedebergs Arch. Pharmacol. pmid:14566450
Wenger T et al. The endogenous cannabinoid, anandamide, activates the hypothalamo-pituitary-adrenal axis in CB1 cannabinoid receptor knockout mice. 2003 Neuroendocrinology pmid:14688442
Tóth A et al. Arachidonyl dopamine as a ligand for the vanilloid receptor VR1 of the rat. 2003 Life Sci. pmid:12759142
Chu CJ et al. N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. 2003 J. Biol. Chem. pmid:12569099