| MeSH term | MeSH ID | Detail |
|---|---|---|
| Brain Ischemia | D002545 | 89 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| De Petrocellis L et al. | Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids. | 2007 | Exp. Cell Res. | pmid:17428469 |
| Richardson D et al. | Quantitative profiling of endocannabinoids and related compounds in rat brain using liquid chromatography-tandem electrospray ionization mass spectrometry. | 2007 | Anal. Biochem. | pmid:17141174 |
| Starowicz K et al. | Biochemistry and pharmacology of endovanilloids. | 2007 | Pharmacol. Ther. | pmid:17349697 |
| Bátkai S et al. | Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17557913 |
| Williams J et al. | Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS. | 2007 | Anal. Chem. | pmid:17600384 |
| Esposito G et al. | Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17545311 |
| Karanian DA et al. | Endocannabinoid enhancement protects against kainic acid-induced seizures and associated brain damage. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17545313 |
| Velenovská M and Fisar Z | Effect of cannabinoids on platelet serotonin uptake. | 2007 | Addict Biol | pmid:17508987 |
| Brizzi A et al. | Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors. | 2007 | Bioorg. Med. Chem. | pmid:17561406 |
| Hill MN et al. | Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity. | 2007 | J. Neurochem. | pmid:17561935 |
| Leweke FM et al. | Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use. | 2007 | Schizophr. Res. | pmid:17566707 |
| Ali AB | Presynaptic Inhibition of GABAA receptor-mediated unitary IPSPs by cannabinoid receptors at synapses between CCK-positive interneurons in rat hippocampus. | 2007 | J. Neurophysiol. | pmid:17567776 |
| Fischbach T et al. | Effects of anandamide and noxious heat on intracellular calcium concentration in nociceptive drg neurons of rats. | 2007 | J. Neurophysiol. | pmid:17581853 |
| Jia Y and Lee LY | Role of TRPV receptors in respiratory diseases. | 2007 | Biochim. Biophys. Acta | pmid:17346945 |
| Solinas M et al. | Nicotinic facilitation of delta9-tetrahydrocannabinol discrimination involves endogenous anandamide. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17351107 |
| Centonze D et al. | The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis. | 2007 | Brain | pmid:17626034 |
| Spivak CE et al. | The endocannabinoid anandamide inhibits the function of alpha4beta2 nicotinic acetylcholine receptors. | 2007 | Mol. Pharmacol. | pmid:17628012 |
| Thors L et al. | Inhibition of the cellular uptake of anandamide by genistein and its analogue daidzein in cells with different levels of fatty acid amide hydrolase-driven uptake. | 2007 | Br. J. Pharmacol. | pmid:17676056 |
| Oz M et al. | The endogenous cannabinoid anandamide inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17682128 |
| Mulè F et al. | Involvement of CB1 and CB2 receptors in the modulation of cholinergic neurotransmission in mouse gastric preparations. | 2007 | Pharmacol. Res. | pmid:17656103 |
| Iuvone T et al. | Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro. | 2007 | J. Mol. Med. | pmid:17639288 |
| Eisenstein TK et al. | Anandamide and Delta9-tetrahydrocannabinol directly inhibit cells of the immune system via CB2 receptors. | 2007 | J. Neuroimmunol. | pmid:17640739 |
| Pakdeechote P et al. | Cannabinoids inhibit noradrenergic and purinergic sympathetic cotransmission in the rat isolated mesenteric arterial bed. | 2007 | Br. J. Pharmacol. | pmid:17641668 |
| Varvel SA et al. | Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. | 2007 | Neuropsychopharmacology | pmid:17047668 |
| Sarchielli P et al. | Endocannabinoids in chronic migraine: CSF findings suggest a system failure. | 2007 | Neuropsychopharmacology | pmid:17119542 |
| Chemin J et al. | Chemical determinants involved in anandamide-induced inhibition of T-type calcium channels. | 2007 | J. Biol. Chem. | pmid:17121818 |
| Yang YY et al. | Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. | 2007 | Liver Int. | pmid:17845532 |
| Ghasemi M et al. | Anandamide improves the impaired nitric oxide-mediated neurogenic relaxation of the corpus cavernosum in diabetic rats: involvement of cannabinoid CB1 and vanilloid VR1 receptors. | 2007 | BJU Int. | pmid:17850365 |
| Cisneros JA et al. | Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase. | 2007 | J. Med. Chem. | pmid:17764163 |
| Vandevoorde S et al. | Lack of selectivity of URB602 for 2-oleoylglycerol compared to anandamide hydrolysis in vitro. | 2007 | Br. J. Pharmacol. | pmid:17143303 |
| Evans RM et al. | Chronic exposure of sensory neurones to increased levels of nerve growth factor modulates CB1/TRPV1 receptor crosstalk. | 2007 | Br. J. Pharmacol. | pmid:17700720 |
| Wheal AJ et al. | Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats. | 2007 | Br. J. Pharmacol. | pmid:17700721 |
| Matias I et al. | Role and regulation of acylethanolamides in energy balance: focus on adipocytes and beta-cells. | 2007 | Br. J. Pharmacol. | pmid:17704823 |
| Herradón E et al. | Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta. | 2007 | Br. J. Pharmacol. | pmid:17704831 |
| Hiley CR and Hoi PM | Oleamide: a fatty acid amide signaling molecule in the cardiovascular system? | 2007 | Cardiovasc Drug Rev | pmid:17445087 |
| Nucci C et al. | Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats. | 2007 | Invest. Ophthalmol. Vis. Sci. | pmid:17591864 |
| Murakami T et al. | Antibacterial cathelicidin peptide CAP11 suppresses the anandamide production from lipopolysaccharide-stimulated mononuclear phagocytes. | 2007 | FEBS Lett. | pmid:17184778 |
| Gasperi V et al. | Endocannabinoids in adipocytes during differentiation and their role in glucose uptake. | 2007 | Cell. Mol. Life Sci. | pmid:17187172 |
| Côté M et al. | Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men. | 2007 | Int J Obes (Lond) | pmid:17224929 |
| Braida D et al. | 5-HT1A receptors are involved in the anxiolytic effect of Delta9-tetrahydrocannabinol and AM 404, the anandamide transport inhibitor, in Sprague-Dawley rats. | 2007 | Eur. J. Pharmacol. | pmid:17116299 |
| Ortar G et al. | New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. | 2007 | J. Med. Chem. | pmid:18027904 |
| Blankman JL et al. | A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. | 2007 | Chem. Biol. | pmid:18096503 |
| Stengel PW et al. | Inhaled anandamide reduces leukotriene D4-induced airway obstruction in guinea pigs. | 2007 | Eur. J. Pharmacol. | pmid:17166495 |
| Xu H et al. | Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene. | 2007 | Am. J. Physiol. Renal Physiol. | pmid:17913835 |
| Athanasiou A et al. | Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17931597 |
| Imming P | Fatty pain cures. | 2007 | Chem. Biol. | pmid:18096498 |
| Morgese MG et al. | Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors. | 2007 | Exp. Neurol. | pmid:17900568 |
| King AR et al. | URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. | 2007 | Chem. Biol. | pmid:18096504 |
| Hillard CJ et al. | Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolase. | 2007 | J. Mol. Neurosci. | pmid:17901541 |
| Opitz CA et al. | Production of the endocannabinoids anandamide and 2-arachidonoylglycerol by endothelial progenitor cells. | 2007 | FEBS Lett. | pmid:17904123 |
| Joshi SR | Endocannabinoid system--a novel target for cardiometabolic risk. | 2007 | J Assoc Physicians India | pmid:17879500 |
| Mitchell VA et al. | Actions of the endocannabinoid transport inhibitor AM404 in neuropathic and inflammatory pain models. | 2007 | Clin. Exp. Pharmacol. Physiol. | pmid:17880375 |
| Romano MR and Lograno MD | Evidence for the involvement of cannabinoid CB1 receptors in the bimatoprost-induced contractions on the human isolated ciliary muscle. | 2007 | Invest. Ophthalmol. Vis. Sci. | pmid:17652738 |
| Bentzen PJ and Lang F | Effect of anandamide on erythrocyte survival. | 2007 | Cell. Physiol. Biochem. | pmid:17975305 |
| Mukhopadhyay S and Tulis DA | Endocannabinoid regulation of matrix metalloproteinases: implications in ischemic stroke. | 2007 | Cardiovasc Hematol Agents Med Chem | pmid:17979695 |
| Soria-Gómez E et al. | Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus. | 2007 | Br. J. Pharmacol. | pmid:17549045 |
| Dainese E et al. | Modulation of the endocannabinoid system by lipid rafts. | 2007 | Curr. Med. Chem. | pmid:17979719 |
| Battista N et al. | The endocannabinoid system in neurodegeneration. | 2006 Sep-Dec | Ital. J. Biochem. | pmid:17274532 |
| Lynch DL and Reggio PH | Cannabinoid CB1 receptor recognition of endocannabinoids via the lipid bilayer: molecular dynamics simulations of CB1 transmembrane helix 6 and anandamide in a phospholipid bilayer. | 2006 Jul-Aug | J. Comput. Aided Mol. Des. | pmid:17106765 |
| Dickason-Chesterfield AK et al. | Pharmacological characterization of endocannabinoid transport and fatty acid amide hydrolase inhibitors. | 2006 Jul-Aug | Cell. Mol. Neurobiol. | pmid:16736384 |
| Schelling G et al. | Effects of general anesthesia on anandamide blood levels in humans. | 2006 | Anesthesiology | pmid:16436846 |
| Guindon J and Beaulieu P | Antihyperalgesic effects of local injections of anandamide, ibuprofen, rofecoxib and their combinations in a model of neuropathic pain. | 2006 | Neuropharmacology | pmid:16442133 |
| Bermúdez-Siva FJ et al. | Activation of cannabinoid CB1 receptors induces glucose intolerance in rats. | 2006 | Eur. J. Pharmacol. | pmid:16423347 |
| Guagnini F et al. | Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P. | 2006 | Gut | pmid:16423891 |
| Meuth SG et al. | The contribution of TWIK-related acid-sensitive K+-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons. | 2006 | Mol. Pharmacol. | pmid:16424077 |
| Marx J | Drug development. Drugs inspired by a drug. | 2006 | Science | pmid:16424309 |
| Cupini LM et al. | Biochemical changes in endocannabinoid system are expressed in platelets of female but not male migraineurs. | 2006 | Cephalalgia | pmid:16472333 |
| GarcÃa Mdel C et al. | Role of CGRP and GABA in the hypotensive effect of intrathecally administered anandamide to anesthetized rats. | 2006 | Eur. J. Pharmacol. | pmid:16472800 |
| Romano MR and Lograno MD | Cannabinoid agonists induce relaxation in the bovine ophthalmic artery: evidences for CB1 receptors, nitric oxide and potassium channels. | 2006 | Br. J. Pharmacol. | pmid:16474412 |
| Fowler CJ | The cannabinoid system and its pharmacological manipulation--a review, with emphasis upon the uptake and hydrolysis of anandamide. | 2006 | Fundam Clin Pharmacol | pmid:17109648 |
| De Lago E et al. | Acyl-based anandamide uptake inhibitors cause rapid toxicity to C6 glioma cells at pharmacologically relevant concentrations. | 2006 | J. Neurochem. | pmid:16899063 |
| Laezza C et al. | Anandamide inhibits Cdk2 and activates Chk1 leading to cell cycle arrest in human breast cancer cells. | 2006 | FEBS Lett. | pmid:17055492 |
| Yeh JH et al. | Effect of anandamide on cytosolic Ca(2+) levels and proliferation in canine renal tubular cells. | 2006 | Basic Clin. Pharmacol. Toxicol. | pmid:16623868 |
| Laviolette SR and Grace AA | The roles of cannabinoid and dopamine receptor systems in neural emotional learning circuits: implications for schizophrenia and addiction. | 2006 | Cell. Mol. Life Sci. | pmid:16699809 |
| Balas L et al. | Synthesis of a potential photoactivatable anandamide analog. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16682198 |
| Shouman B et al. | Endocannabinoids potently protect the newborn brain against AMPA-kainate receptor-mediated excitotoxic damage. | 2006 | Br. J. Pharmacol. | pmid:16682966 |
| Zaniewska M et al. | Evaluation of the role of nicotinic acetylcholine receptor subtypes and cannabinoid system in the discriminative stimulus effects of nicotine in rats. | 2006 | Eur. J. Pharmacol. | pmid:16730696 |
| Harada N et al. | Antithrombin reduces endotoxin-induced hypotension by enhancing pulmonary sensory neuron activation in rats. | 2006 | Thromb. Haemost. | pmid:16732381 |
| van der Stelt M et al. | Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels. | 2006 | Cell. Mol. Life Sci. | pmid:16732431 |
| Fisyunov A et al. | Cannabinoids modulate the P-type high-voltage-activated calcium currents in purkinje neurons. | 2006 | J. Neurophysiol. | pmid:16738209 |
| Vogeser M et al. | Release of anandamide from blood cells. | 2006 | Clin. Chem. Lab. Med. | pmid:16599845 |
| Kopczyńska B and Szereda-Przestaszewska M | Supranodose vagotomy eliminates anandamide-evoked cardiorespiratory depression in anaesthetized rats. | 2006 | Respir Physiol Neurobiol | pmid:16144778 |
| Wang Y et al. | A novel scintillation proximity assay for fatty acid amide hydrolase compatible with inhibitor screening. | 2006 | Anal. Biochem. | pmid:16707086 |
| Wiles AL et al. | N-Arachidonyl-glycine inhibits the glycine transporter, GLYT2a. | 2006 | J. Neurochem. | pmid:16899062 |
| Bai X et al. | TASK channel expression in human placenta and cytotrophoblast cells. | 2006 | J. Soc. Gynecol. Investig. | pmid:16378911 |
| Hejazi N et al. | Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors. | 2006 | Mol. Pharmacol. | pmid:16332990 |
| Bojesen IN and Hansen HS | Effect of an unstirred layer on the membrane permeability of anandamide. | 2006 | J. Lipid Res. | pmid:16365480 |
| Dembiński A et al. | Cannabinoids in acute gastric damage and pancreatitis. | 2006 | J. Physiol. Pharmacol. | pmid:17218765 |
| D'Argenio G et al. | Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. | 2006 | FASEB J. | pmid:16403786 |
| Nakajima Y et al. | Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition. | 2006 | FEBS Lett. | pmid:16406050 |
| Suplita RL et al. | Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia. | 2006 | Neuropharmacology | pmid:16316669 |
| Avelino A and Cruz F | TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications. | 2006 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:16721555 |
| Murillo-Rodriguez E et al. | Diurnal variation of arachidonoylethanolamine, palmitoylethanolamide and oleoylethanolamide in the brain of the rat. | 2006 | Life Sci. | pmid:16434061 |
| Juan-Picó P et al. | Cannabinoid receptors regulate Ca(2+) signals and insulin secretion in pancreatic beta-cell. | 2006 | Cell Calcium | pmid:16321437 |
| Moezi L et al. | Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB(1) and VR(1) receptors. | 2006 | Br. J. Pharmacol. | pmid:17043671 |
| de Lago E et al. | UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders. | 2006 | Eur Neuropsychopharmacol | pmid:16006105 |
| Ligresti A et al. | New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis. | 2006 | Br. J. Pharmacol. | pmid:16284631 |
| Bir LS and Ercan S | Effects of intrathecal anandamide on somatosensory evoked responses in rats. | 2006 | Exp. Neurol. | pmid:16289169 |
| Urbani P et al. | New metabolically stable fatty acid amide ligands of cannabinoid receptors: Synthesis and receptor affinity studies. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16213718 |
| Malfitano AM et al. | Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis. | 2006 | J. Neuroimmunol. | pmid:16239036 |