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The relationship between plasma levels of the endocannabinoid, anandamide, sex steroids, and gonadotrophins during the menstrual cycle. |
2010 |
Fertil. Steril. |
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Opposite effects of anandamide and N-arachidonoyl dopamine in the regulation of prostaglandin E and 8-iso-PGF formation in primary glial cells. |
2009 |
J. Neurochem. |
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Cannabinoid receptors as novel therapeutic targets for the management of non-alcoholic steatohepatitis. |
2008 |
Diabetes Metab. |
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17beta-oestradiol and progesterone regulate anandamide synthesis in the rat uterus. |
2009 |
Reprod. Biomed. Online |
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The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. |
2008 Nov-Dec |
Anticancer Res. |
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A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis. |
2010 |
Invest New Drugs |
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Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells. |
2009 |
Am. J. Respir. Cell Mol. Biol. |
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Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation. |
2009 |
AAPS J |
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Functional characterization of nonadrenergic noncholinergic neurotransmitter release via endocannabinoids: an in vitro study in rabbit corpus cavernosum. |
2009 |
J Sex Med |
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A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonist. |
2009 |
Mol. Pharmacol. |
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Total synthesis of photoactivatable or fluorescent anandamide probes: novel bioactive compounds with angiogenic activity. |
2009 |
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Role of cannabinoid CB1 receptors on macronutrient selection and satiety in rats. |
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Physiol. Behav. |
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Metabolism of anandamide by COX-2 is necessary for endocannabinoid-induced cell death in tumorigenic keratinocytes. |
2009 |
Mol. Carcinog. |
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Editorial comment on: localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. |
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Eur. Urol. |
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Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. |
2010 |
Eur. Urol. |
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Effect of cannabinoids upon the uptake of folic acid by BeWo cells. |
2009 |
Pharmacology |
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Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid. |
2009 |
J Neural Transm |
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Acid-sensitive TASK-like K+ conductances contribute to resting membrane potential and to orexin-induced membrane depolarization in rat thalamic paraventricular nucleus neurons. |
2009 |
Neuroscience |
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Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats. |
2009 |
Br. J. Pharmacol. |
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Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. |
2009 |
Brain Res. |
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Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors. |
2009 |
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Anandamide preserves cardiac function and geometry in an acute doxorubicin cardiotoxicity rat model. |
2009 |
J. Cardiovasc. Pharmacol. Ther. |
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Biology of endocannabinoid synthesis system. |
2009 |
Prostaglandins Other Lipid Mediat. |
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Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activity. |
2009 |
Eur. J. Neurosci. |
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N-acyldopamines control striatal input terminals via novel ligand-gated cation channels. |
2009 |
Neuropharmacology |
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Effects of hypertension on vasorelaxation to endocannabinoids in vitro. |
2009 |
Eur. J. Pharmacol. |
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Low type I cannabinoid receptor levels characterize placental villous in labouring delivery. |
2009 |
Placenta |
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Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase. |
2009 |
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Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle. |
2009 |
Diabetologia |
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Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages. |
2009 |
Cardiovasc. Res. |
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The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption. |
2009 |
Bone |
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Radiosynthesis, in vitro and in vivo evaluation of 123I-labeled anandamide analogues for mapping brain FAAH. |
2009 |
Bioorg. Med. Chem. |
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The endocannabinoid system in bull sperm and bovine oviductal epithelium: role of anandamide in sperm-oviduct interaction. |
2009 |
Reproduction |
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Mass-spectrometric identification of anandamide and 2-arachidonoylglycerol in nematodes. |
2008 |
Chem. Biodivers. |
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The endocannabinoid anandamide inhibits potassium conductance in rat cortical astrocytes. |
2009 |
Glia |
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Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. |
2009 |
Nat. Chem. Biol. |
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The endocannabinoid anandamide inhibits kinin B1 receptor sensitization through cannabinoid CB1 receptor stimulation in human umbilical vein. |
2009 |
Eur. J. Pharmacol. |
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Antinociceptive interactions between anandamide and endomorphin-1 at the spinal level. |
2009 |
Clin. Exp. Pharmacol. Physiol. |
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Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide. |
2009 |
J. Lipid Res. |
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Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats. |
2009 |
Psychopharmacology (Berl.) |
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Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals. |
2009 |
Bioorg. Med. Chem. Lett. |
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Endocannabinoid-mediated enhancement of fear-conditioned analgesia in rats: opioid receptor dependency and molecular correlates. |
2008 |
Pain |
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Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. |
2009 |
Psychopharmacology (Berl.) |
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Genetic loss of Faah compromises male fertility in mice. |
2009 |
Biol. Reprod. |
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Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents. |
2008 |
J Neural Transm |
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A decrease in anandamide signaling contributes to the maintenance of cutaneous mechanical hyperalgesia in a model of bone cancer pain. |
2008 |
J. Neurosci. |
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[Analysis of central mechanisms involved in gastric mucosal integrity]. |
2008 |
Neuropsychopharmacol Hung |
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Trezza V and Vanderschuren LJ |
Divergent effects of anandamide transporter inhibitors with different target selectivity on social play behavior in adolescent rats. |
2009 |
J. Pharmacol. Exp. Ther. |
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Removal of 2-arachidonylglycerol by direct hemoperfusion therapy with polymyxin B immobilized fibers benefits patients with septic shock. |
2008 |
Ther Apher Dial |
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Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat. |
2009 |
Gut |
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The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice. |
2009 |
Neurobiol. Dis. |
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TRPV1 channels facilitate glutamate transmission in the striatum. |
2009 |
Mol. Cell. Neurosci. |
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The endocannabinoid system is modulated in response to spinal cord injury in rats. |
2009 |
Neurobiol. Dis. |
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Bambico FR and Gobbi G |
The cannabinoid CB1 receptor and the endocannabinoid anandamide: possible antidepressant targets. |
2008 |
Expert Opin. Ther. Targets |
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A role for CB2 receptors in anandamide signalling pathways involved in the regulation of IL-12 and IL-23 in microglial cells. |
2009 |
Biochem. Pharmacol. |
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Rod-shaped nanocrystals elicit neuronal activity in vivo. |
2008 |
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The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway. |
2008 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Kurjak M et al. |
Differential stimulatory effects of cannabinoids on VIP release and NO synthase activity in synaptosomal fractions from rat ileum. |
2008 Oct-Dec |
Neuropeptides |
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Direct activation of transient receptor potential vanilloid 1(TRPV1) by diacylglycerol (DAG). |
2008 |
Mol Pain |
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A solid-phase method for the extraction and measurement of anandamide from multiple human biomatrices. |
2009 |
Anal. Biochem. |
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The anandamide membrane transporter inhibitor, VDM-11, modulates sleep and c-Fos expression in the rat brain. |
2008 |
Neuroscience |
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Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol. |
2009 |
J. Mol. Med. |
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Differential alteration of hippocampal excitatory synaptic transmission by cannabinoid ligands. |
2009 |
J. Neurosci. Res. |
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Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates. |
2008 |
Biol. Psychiatry |
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CB1 cannabinoid receptor-dependent and -independent inhibition of depolarization-induced calcium influx in oligodendrocytes. |
2009 |
Glia |
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Expression and secretion of N-acylethanolamine-hydrolysing acid amidase in human prostate cancer cells. |
2008 |
J. Biochem. |
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Synthesis of all-trans anandamide: a substrate for fatty acid amide hydrolase with dual effects on rabbit platelet activation. |
2008 |
Bioorg. Med. Chem. |
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Cannabimimetic effects modulated by cholinergic compounds. |
2008 |
Addict Biol |
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Fowler CJ |
"The tools of the trade"--an overview of the pharmacology of the endocannabinoid system. |
2008 |
Curr. Pharm. Des. |
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Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol. |
2008 |
J. Neurochem. |
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Elevated temperatures alter TRPV1 agonist-evoked excitability of dorsal root ganglion neurons. |
2008 |
Inflamm. Res. |
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Anandamide effects on 5-HT(3) receptors in vivo. |
2008 |
Eur. J. Pharmacol. |
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Haller VL et al. |
Modulation of opioids via protection of anandamide degradation by fatty acid amide hydrolase. |
2008 |
Eur. J. Pharmacol. |
pmid:18762181
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Tuboly G et al. |
The antinociceptive interaction of anandamide and adenosine at the spinal level. |
2009 |
Pharmacol. Biochem. Behav. |
pmid:18760296
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Placzek EA et al. |
Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown. |
2008 |
Neuropharmacology |
pmid:18760289
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Acute effects of endocannabinoid anandamide and CB1 receptor antagonist, AM251 in the regulation of thyrotropin secretion. |
2008 |
J. Endocrinol. |
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Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine. |
2008 |
Biochem. Pharmacol. |
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Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats. |
2008 |
J. Pharmacol. Exp. Ther. |
pmid:18725543
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Yao F et al. |
Development of novel tail-modified anandamide analogs. |
2008 |
Bioorg. Med. Chem. Lett. |
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Moezi L et al. |
Endocannabinoids and liver disease. V. endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis. |
2008 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:18703639
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Williams JL et al. |
K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro. |
2008 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:18703414
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Woodward DF et al. |
The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products. |
2008 |
Pharmacol. Ther. |
pmid:18700152
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Snider NT et al. |
The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6. |
2008 |
J. Pharmacol. Exp. Ther. |
pmid:18698000
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Ho WS et al. |
'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors. |
2008 |
Br. J. Pharmacol. |
pmid:18695637
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Currie S et al. |
IP(3)R-mediated Ca(2+) release is modulated by anandamide in isolated cardiac nuclei. |
2008 |
J. Mol. Cell. Cardiol. |
pmid:18692061
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Clapper JR et al. |
The endocannabinoid system as a target for the treatment of cannabis dependence. |
2009 |
Neuropharmacology |
pmid:18691603
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Lisboa SF et al. |
Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test. |
2008 |
Eur. J. Pharmacol. |
pmid:18691568
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Hashiguchi T et al. |
Systematic evaluation of nitric oxide, tetrahydrobiopterin, and anandamide levels in a porcine model of endotoxemia. |
2008 |
J Anesth |
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Fowler CJ and Ghafouri N |
Does the hydrolysis of 2-arachidonoylglycerol regulate its cellular uptake? |
2008 |
Pharmacol. Res. |
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Ellgren M et al. |
Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. |
2008 |
Eur Neuropsychopharmacol |
pmid:18674887
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Maione S et al. |
Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non-cannabinoid receptor-mediated mechanisms. |
2008 |
Br. J. Pharmacol. |
pmid:18660824
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Kudo R and Hatake K |
[Effect of ethanol on anandamide-induced sensory nerve dependent vasorelaxation (the second report)]. |
2008 |
Nihon Arukoru Yakubutsu Igakkai Zasshi |
pmid:18646646
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Hill MN et al. |
Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment. |
2008 |
J. Neurochem. |
pmid:18643796
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Maccarrone M |
Anandamide as a marker of human disease. |
2008 |
JAMA |
pmid:18632539
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Turco MY et al. |
High levels of anandamide, an endogenous cannabinoid, block the growth of sheep preimplantation embryos by inducing apoptosis and reversible arrest of cell proliferation. |
2008 |
Hum. Reprod. |
pmid:18614613
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Habayeb OM et al. |
Expression of the endocannabinoid system in human first trimester placenta and its role in trophoblast proliferation. |
2008 |
Endocrinology |
pmid:18599552
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Farrell EK and Merkler DJ |
Biosynthesis, degradation and pharmacological importance of the fatty acid amides. |
2008 |
Drug Discov. Today |
pmid:18598910
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Dembiński A et al. |
Dual, time-dependent deleterious and protective effect of anandamide on the course of cerulein-induced acute pancreatitis. Role of sensory nerves. |
2008 |
Eur. J. Pharmacol. |
pmid:18593574
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McMahon LR |
Apparent affinity estimates of rimonabant in combination with anandamide and chemical analogs of anandamide in rhesus monkeys discriminating Delta9-tetrahydrocannabinol. |
2009 |
Psychopharmacology (Berl.) |
pmid:18592221
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Liu HY et al. |
[Effects of anandamide on the activation and proliferation of hepatic stellate cells through cannabinoid-2 receptors]. |
2008 |
Zhonghua Gan Zang Bing Za Zhi |
pmid:18578993
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