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Mol. Pharmacol. |
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Nat. Chem. Biol. |
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Activation of CB1 cannabinoid receptors in the dorsolateral periaqueductal gray reduces the expression of contextual fear conditioning in rats. |
2008 |
Psychopharmacology (Berl.) |
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Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat. |
2008 |
Psychopharmacology (Berl.) |
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Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents. |
2008 |
Neuroimage |
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Endocannabinoids: synthesis and degradation. |
2008 |
Rev. Physiol. Biochem. Pharmacol. |
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Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond. |
2008 |
Addict Biol |
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Impairment of endocannabinoids activity in the dorsolateral striatum delays extinction of behavior in a procedural memory task in rats. |
2008 |
Neuropharmacology |
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Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog. |
2009 |
Psychopharmacology (Berl.) |
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Abnormalities in the cerebrospinal fluid levels of endocannabinoids in multiple sclerosis. |
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J. Neurol. Neurosurg. Psychiatr. |
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Curr. Med. Chem. |
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N-arachidonylethanolamide-induced increase in aqueous humor outflow facility. |
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Invest. Ophthalmol. Vis. Sci. |
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Fatty acid amide hydrolase inhibition enhances the anti-allodynic actions of endocannabinoids in a model of acute pain adapted for the mouse. |
2008 |
Neuroscience |
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Expression and purification of orphan cytochrome P450 4X1 and oxidation of anandamide. |
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FEBS J. |
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J. Neurosci. |
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[Sensitization of cough sensitivity through activation of C-and/or Adelta fibers]. |
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Br. J. Pharmacol. |
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Opposite action of hippocampal CB1 receptors in memory reconsolidation and extinction. |
2008 |
Neuroscience |
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Ultra performance liquid chromatography tandem mass spectrometry method for the measurement of anandamide in human plasma. |
2008 |
Anal. Biochem. |
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Dual effect of anandamide on rat placenta nitric oxide synthesis. |
2008 |
Placenta |
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The preventive effect of cannabinoids on reperfusion-induced ischemia of mouse kidney. |
2008 |
Exp. Toxicol. Pathol. |
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[Effects of anandamide on the activation and proliferation of hepatic stellate cells through cannabinoid-2 receptors]. |
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Apparent affinity estimates of rimonabant in combination with anandamide and chemical analogs of anandamide in rhesus monkeys discriminating Delta9-tetrahydrocannabinol. |
2009 |
Psychopharmacology (Berl.) |
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Dual, time-dependent deleterious and protective effect of anandamide on the course of cerulein-induced acute pancreatitis. Role of sensory nerves. |
2008 |
Eur. J. Pharmacol. |
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Farrell EK and Merkler DJ |
Biosynthesis, degradation and pharmacological importance of the fatty acid amides. |
2008 |
Drug Discov. Today |
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Expression of the endocannabinoid system in human first trimester placenta and its role in trophoblast proliferation. |
2008 |
Endocrinology |
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High levels of anandamide, an endogenous cannabinoid, block the growth of sheep preimplantation embryos by inducing apoptosis and reversible arrest of cell proliferation. |
2008 |
Hum. Reprod. |
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Anandamide as a marker of human disease. |
2008 |
JAMA |
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Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment. |
2008 |
J. Neurochem. |
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[Effect of ethanol on anandamide-induced sensory nerve dependent vasorelaxation (the second report)]. |
2008 |
Nihon Arukoru Yakubutsu Igakkai Zasshi |
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Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non-cannabinoid receptor-mediated mechanisms. |
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Br. J. Pharmacol. |
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Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. |
2008 |
Eur Neuropsychopharmacol |
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Does the hydrolysis of 2-arachidonoylglycerol regulate its cellular uptake? |
2008 |
Pharmacol. Res. |
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Systematic evaluation of nitric oxide, tetrahydrobiopterin, and anandamide levels in a porcine model of endotoxemia. |
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J Anesth |
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Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test. |
2008 |
Eur. J. Pharmacol. |
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The endocannabinoid system as a target for the treatment of cannabis dependence. |
2009 |
Neuropharmacology |
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2008 |
J. Mol. Cell. Cardiol. |
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'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors. |
2008 |
Br. J. Pharmacol. |
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The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6. |
2008 |
J. Pharmacol. Exp. Ther. |
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The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products. |
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Pharmacol. Ther. |
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K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro. |
2008 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
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Endocannabinoids and liver disease. V. endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis. |
2008 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Development of novel tail-modified anandamide analogs. |
2008 |
Bioorg. Med. Chem. Lett. |
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Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats. |
2008 |
J. Pharmacol. Exp. Ther. |
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Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine. |
2008 |
Biochem. Pharmacol. |
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Acute effects of endocannabinoid anandamide and CB1 receptor antagonist, AM251 in the regulation of thyrotropin secretion. |
2008 |
J. Endocrinol. |
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Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown. |
2008 |
Neuropharmacology |
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The antinociceptive interaction of anandamide and adenosine at the spinal level. |
2009 |
Pharmacol. Biochem. Behav. |
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Modulation of opioids via protection of anandamide degradation by fatty acid amide hydrolase. |
2008 |
Eur. J. Pharmacol. |
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Anandamide effects on 5-HT(3) receptors in vivo. |
2008 |
Eur. J. Pharmacol. |
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Elevated temperatures alter TRPV1 agonist-evoked excitability of dorsal root ganglion neurons. |
2008 |
Inflamm. Res. |
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Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol. |
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J. Neurochem. |
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Fowler CJ |
"The tools of the trade"--an overview of the pharmacology of the endocannabinoid system. |
2008 |
Curr. Pharm. Des. |
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Cannabimimetic effects modulated by cholinergic compounds. |
2008 |
Addict Biol |
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Synthesis of all-trans anandamide: a substrate for fatty acid amide hydrolase with dual effects on rabbit platelet activation. |
2008 |
Bioorg. Med. Chem. |
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Expression and secretion of N-acylethanolamine-hydrolysing acid amidase in human prostate cancer cells. |
2008 |
J. Biochem. |
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CB1 cannabinoid receptor-dependent and -independent inhibition of depolarization-induced calcium influx in oligodendrocytes. |
2009 |
Glia |
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Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates. |
2008 |
Biol. Psychiatry |
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Differential alteration of hippocampal excitatory synaptic transmission by cannabinoid ligands. |
2009 |
J. Neurosci. Res. |
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Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol. |
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J. Mol. Med. |
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The anandamide membrane transporter inhibitor, VDM-11, modulates sleep and c-Fos expression in the rat brain. |
2008 |
Neuroscience |
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A solid-phase method for the extraction and measurement of anandamide from multiple human biomatrices. |
2009 |
Anal. Biochem. |
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Direct activation of transient receptor potential vanilloid 1(TRPV1) by diacylglycerol (DAG). |
2008 |
Mol Pain |
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Differential stimulatory effects of cannabinoids on VIP release and NO synthase activity in synaptosomal fractions from rat ileum. |
2008 Oct-Dec |
Neuropeptides |
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The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway. |
2008 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Rod-shaped nanocrystals elicit neuronal activity in vivo. |
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Small |
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A role for CB2 receptors in anandamide signalling pathways involved in the regulation of IL-12 and IL-23 in microglial cells. |
2009 |
Biochem. Pharmacol. |
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Bambico FR and Gobbi G |
The cannabinoid CB1 receptor and the endocannabinoid anandamide: possible antidepressant targets. |
2008 |
Expert Opin. Ther. Targets |
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The endocannabinoid system is modulated in response to spinal cord injury in rats. |
2009 |
Neurobiol. Dis. |
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TRPV1 channels facilitate glutamate transmission in the striatum. |
2009 |
Mol. Cell. Neurosci. |
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The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice. |
2009 |
Neurobiol. Dis. |
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Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat. |
2009 |
Gut |
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Removal of 2-arachidonylglycerol by direct hemoperfusion therapy with polymyxin B immobilized fibers benefits patients with septic shock. |
2008 |
Ther Apher Dial |
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Trezza V and Vanderschuren LJ |
Divergent effects of anandamide transporter inhibitors with different target selectivity on social play behavior in adolescent rats. |
2009 |
J. Pharmacol. Exp. Ther. |
pmid:18948500
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Gyires K and Zádori Z |
[Analysis of central mechanisms involved in gastric mucosal integrity]. |
2008 |
Neuropsychopharmacol Hung |
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Khasabova IA et al. |
A decrease in anandamide signaling contributes to the maintenance of cutaneous mechanical hyperalgesia in a model of bone cancer pain. |
2008 |
J. Neurosci. |
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Hill MN et al. |
Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents. |
2008 |
J Neural Transm |
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Sun X et al. |
Genetic loss of Faah compromises male fertility in mice. |
2009 |
Biol. Reprod. |
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Schacht JP et al. |
Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. |
2009 |
Psychopharmacology (Berl.) |
pmid:19002671
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Butler RK et al. |
Endocannabinoid-mediated enhancement of fear-conditioned analgesia in rats: opioid receptor dependency and molecular correlates. |
2008 |
Pain |
pmid:19004548
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Aneetha H et al. |
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals. |
2009 |
Bioorg. Med. Chem. Lett. |
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Panlilio LV et al. |
Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats. |
2009 |
Psychopharmacology (Berl.) |
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Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide. |
2009 |
J. Lipid Res. |
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Tuboly G et al. |
Antinociceptive interactions between anandamide and endomorphin-1 at the spinal level. |
2009 |
Clin. Exp. Pharmacol. Physiol. |
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Pelorosso FG et al. |
The endocannabinoid anandamide inhibits kinin B1 receptor sensitization through cannabinoid CB1 receptor stimulation in human umbilical vein. |
2009 |
Eur. J. Pharmacol. |
pmid:19022239
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Long JZ et al. |
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. |
2009 |
Nat. Chem. Biol. |
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The endocannabinoid anandamide inhibits potassium conductance in rat cortical astrocytes. |
2009 |
Glia |
pmid:19031444
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Lehtonen M et al. |
Mass-spectrometric identification of anandamide and 2-arachidonoylglycerol in nematodes. |
2008 |
Chem. Biodivers. |
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Gervasi MG et al. |
The endocannabinoid system in bull sperm and bovine oviductal epithelium: role of anandamide in sperm-oviduct interaction. |
2009 |
Reproduction |
pmid:19042982
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Wyffels L et al. |
Radiosynthesis, in vitro and in vivo evaluation of 123I-labeled anandamide analogues for mapping brain FAAH. |
2009 |
Bioorg. Med. Chem. |
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The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption. |
2009 |
Bone |
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Jiang LS et al. |
Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages. |
2009 |
Cardiovasc. Res. |
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Eckardt K et al. |
Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle. |
2009 |
Diabetologia |
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Karbarz MJ et al. |
Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase. |
2009 |
Anesth. Analg. |
pmid:19095868
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Acone G et al. |
Low type I cannabinoid receptor levels characterize placental villous in labouring delivery. |
2009 |
Placenta |
pmid:19097644
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Wheal AJ and Randall MD |
Effects of hypertension on vasorelaxation to endocannabinoids in vitro. |
2009 |
Eur. J. Pharmacol. |
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Ferreira SG et al. |
N-acyldopamines control striatal input terminals via novel ligand-gated cation channels. |
2009 |
Neuropharmacology |
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Adermark L et al. |
Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activity. |
2009 |
Eur. J. Neurosci. |
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Wang J and Ueda N |
Biology of endocannabinoid synthesis system. |
2009 |
Prostaglandins Other Lipid Mediat. |
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