| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetic Retinopathy | D003930 | 39 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wartmann M et al. | The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide. | 1995 | FEBS Lett. | pmid:7867785 |
| Bornheim LM et al. | Microsomal cytochrome P450-mediated liver and brain anandamide metabolism. | 1995 | Biochem. Pharmacol. | pmid:7669071 |
| Desarnaud F et al. | Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization. | 1995 | J. Biol. Chem. | pmid:7890734 |
| Hillard CJ et al. | Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain. | 1995 | Biochim. Biophys. Acta | pmid:7647100 |
| Fride E et al. | Low doses of anandamides inhibit pharmacological effects of delta 9-tetrahydrocannabinol. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7853184 |
| Adams IB et al. | Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7791088 |
| Di Marzo V and Fontana A | Anandamide, an endogenous cannabinomimetic eicosanoid: 'killing two birds with one stone'. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7675818 |
| Romero J et al. | Changes in rat brain cannabinoid binding sites after acute or chronic exposure to their endogenous agonist, anandamide, or to delta 9-tetrahydrocannabinol. | 1995 | Pharmacol. Biochem. Behav. | pmid:7675852 |
| Das SK et al. | Cannabinoid ligand-receptor signaling in the mouse uterus. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7753807 |
| Fan P | Cannabinoid agonists inhibit the activation of 5-HT3 receptors in rat nodose ganglion neurons. | 1995 | J. Neurophysiol. | pmid:7760148 |
| Ueda N et al. | Oxygenation of arachidonylethanolamide (anandamide) by lipoxygenases. | 1995 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:7732825 |
| Facci L et al. | Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7724569 |
| Fride E | Anandamides: tolerance and cross-tolerance to delta 9-tetrahydrocannabinol. | 1995 | Brain Res. | pmid:8593598 |
| Burstein SH et al. | Relationships between eicosanoids and cannabinoids. Are eicosanoids cannabimimetic agents?. | 1995 | Biochem. Pharmacol. | pmid:8615850 |
| Hampson AJ et al. | Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor. | 1995 | Biochim. Biophys. Acta | pmid:7488638 |
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| Schmid PC et al. | Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain. | 1995 | FEBS Lett. | pmid:7498458 |
| Sugiura T et al. | 2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7575630 |
| Guzmán M et al. | Effects of anandamide on hepatic fatty acid metabolism. | 1995 | Biochem. Pharmacol. | pmid:7575652 |
| Ueda N et al. | Partial purification and characterization of the porcine brain enzyme hydrolyzing and synthesizing anandamide. | 1995 | J. Biol. Chem. | pmid:7559559 |
| Venance L et al. | Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes. | 1995 | Nature | pmid:7637807 |
| Ueda N | [Anandamide: an endogenous cannabinoid receptor agonist]. | 1995 | Seikagaku | pmid:7594870 |
| Varga K et al. | Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide. | 1995 | Eur. J. Pharmacol. | pmid:7589169 |
| Mechoulam R et al. | Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. | 1995 | Biochem. Pharmacol. | pmid:7605349 |
| Felder CC et al. | Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. | 1995 | Mol. Pharmacol. | pmid:7565624 |
| Vela G et al. | Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine. | 1995 | Neuropharmacology | pmid:7566503 |
| Paria BC et al. | The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7568154 |
| Burstein SH and Hunter SA | Stimulation of anandamide biosynthesis in N-18TG2 neuroblastoma cells by delta 9-tetrahydrocannabinol (THC). | 1995 | Biochem. Pharmacol. | pmid:7702643 |
| Priller J et al. | Mead ethanolamide, a novel eicosanoid, is an agonist for the central (CB1) and peripheral (CB2) cannabinoid receptors. | 1995 | Mol. Pharmacol. | pmid:7651362 |
| Ellis EF et al. | Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin. | 1995 | Am. J. Physiol. | pmid:8594893 |
| Pertwee RG et al. | Effect of phenylmethylsulphonyl fluoride on the potency of anandamide as an inhibitor of electrically evoked contractions in two isolated tissue preparations. | 1995 | Eur. J. Pharmacol. | pmid:7713152 |
| Hansen HS et al. | Glutamate stimulates the formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cortical neurons in culture. | 1995 | Biochim. Biophys. Acta | pmid:7548201 |
| Edgemond WS et al. | The binding of novel phenolic derivatives of anandamide to brain cannabinoid receptors. | 1995 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7784462 |
| Koga D et al. | High-performance liquid chromatography and fluorometric detection of arachidonylethanolamide (anandamide) and its analogues, derivatized with 4-(N-chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulp honyl-2,1 ,3- benzoxadiazole (DBD-COCl). | 1995 Jan-Feb | Biomed. Chromatogr. | pmid:7734936 |
| Wise ML et al. | Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid. | 1996 | Experientia | pmid:8575565 |
| Pan X et al. | Rat brain cannabinoid receptor modulates N-type Ca2+ channels in a neuronal expression system. | 1996 | Mol. Pharmacol. | pmid:8609900 |
| Fride E and Mechoulam R | Developmental aspects of anandamide: ontogeny of response and prenatal exposure. | 1996 | Psychoneuroendocrinology | pmid:8774060 |
| Showalter VM et al. | Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. | 1996 | J. Pharmacol. Exp. Ther. | pmid:8819477 |
| Felder CC et al. | Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat. | 1996 | FEBS Lett. | pmid:8814296 |
| di Tomaso E et al. | Brain cannabinoids in chocolate. | 1996 | Nature | pmid:8751435 |
| Cadas H et al. | Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP. | 1996 | J. Neurosci. | pmid:8656287 |
| Kempe K et al. | Isotope dilution mass spectrometric measurements indicate that arachidonylethanolamide, the proposed endogenous ligand of the cannabinoid receptor, accumulates in rat brain tissue post mortem but is contained at low levels in or is absent from fresh tissue. | 1996 | J. Biol. Chem. | pmid:8663381 |
| Stefano GB et al. | Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. | 1996 | J. Biol. Chem. | pmid:8702604 |
| Di Marzo V et al. | Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. | 1996 | Biochem. J. | pmid:8670178 |
| Cravatt BF et al. | Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. | 1996 | Nature | pmid:8900284 |
| Sugiura T et al. | N-arachidonoylethanolamine (anandamide), an endogenous cannabinoid receptor ligand, and related lipid molecules in the nervous tissues. | 1996 | J Lipid Mediat Cell Signal | pmid:8906545 |
| Ueda N et al. | Enzymes for anandamide biosynthesis and metabolism. | 1996 | J Lipid Mediat Cell Signal | pmid:8906546 |
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| Stein EA et al. | Physiological and behavioural effects of the endogenous cannabinoid, arachidonylethanolamide (anandamide), in the rat. | 1996 | Br. J. Pharmacol. | pmid:8872363 |
| Sugiura T et al. | Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine. | 1996 | Eur. J. Biochem. | pmid:8797835 |