Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Orthostatic Intolerance D054971 1 associated lipids
Schistosomiasis japonica D012554 3 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Acute Pain D059787 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Derkinderen P et al. Regulation of a neuronal form of focal adhesion kinase by anandamide. 1996 Science pmid:8781236
Shimasue K et al. Effects of anandamide and arachidonic acid on specific binding of (+) -PN200-110, diltiazem and (-) -desmethoxyverapamil to L-type Ca2+ channel. 1996 Eur. J. Pharmacol. pmid:8904088
Sugiura T et al. Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities. 1996 Biochem. Biophys. Res. Commun. pmid:8573114
Shivachar AC et al. Anandamide- and delta9-tetrahydrocannabinol-evoked arachidonic acid mobilization and blockade by SR141716A [N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4 -methyl-1H-pyrazole-3-carboximide hydrochloride]. 1996 Biochem. Pharmacol. pmid:8615904
Stefano GB et al. Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. 1996 J. Biol. Chem. pmid:8702604
Di Marzo V et al. Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. 1996 Biochem. J. pmid:8670178
Ueda N et al. Enzymes for anandamide biosynthesis and metabolism. 1996 J Lipid Mediat Cell Signal pmid:8906546
Yang ZM et al. Activation of brain-type cannabinoid receptors interferes with preimplantation mouse embryo development. 1996 Biol. Reprod. pmid:8879486
Varga K et al. Mechanism of the hypotensive action of anandamide in anesthetized rats. 1996 Hypertension pmid:8843898
Poling JS et al. Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. 1996 Neuropharmacology pmid:8938728
Di Marzo V et al. Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells. 1996 Biochem. Biophys. Res. Commun. pmid:8858137
Ishac EJ et al. Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves. 1996 Br. J. Pharmacol. pmid:8864538
Fride E and Mechoulam R Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice. 1996 Brain Res. Dev. Brain Res. pmid:8873985
Thomas BF et al. Structure-activity analysis of anandamide analogs: relationship to a cannabinoid pharmacophore. 1996 J. Med. Chem. pmid:8558515
Boring DL et al. Cerebrodiene, arachidonyl-ethanolamide, and hybrid structures: potential for interaction with brain cannabinoid receptors. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8931121
Berdyshev EV et al. Anandamide--a new look on fatty acid ethanolamides. 1996 J Lipid Mediat Cell Signal pmid:9029374
Paria BC et al. The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period. 1996 Mol. Reprod. Dev. pmid:8914076
Khanolkar AD et al. Head group analogs of arachidonylethanolamide, the endogenous cannabinoid ligand. 1996 J. Med. Chem. pmid:8893848
Koga D et al. High-performance liquid chromatography and fluorometric detection of arachidonylethanolamide (anandamide) and its analogues, derivatized with 4-(N-chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulp honyl-2,1 ,3- benzoxadiazole (DBD-COCl). 1995 Jan-Feb Biomed. Chromatogr. pmid:7734936
Edgemond WS et al. The binding of novel phenolic derivatives of anandamide to brain cannabinoid receptors. 1995 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:7784462