Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Pregnancy, Ectopic D011271 5 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Anorexia D000855 8 associated lipids
Morphine Dependence D009021 9 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Alveolar Bone Loss D016301 10 associated lipids
Migraine Disorders D008881 11 associated lipids
Learning Disorders D007859 11 associated lipids
Hyperkinesis D006948 11 associated lipids
Hepatitis D006505 11 associated lipids
Shock, Septic D012772 11 associated lipids
Overweight D050177 11 associated lipids
Hypertension, Portal D006975 12 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Bradycardia D001919 13 associated lipids
Neoplasms D009369 13 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
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Authors Title Published Journal PubMed Link
Kaplan BL et al. Inhibition of leukocyte function and interleukin-2 gene expression by 2-methylarachidonyl-(2'-fluoroethyl)amide, a stable congener of the endogenous cannabinoid receptor ligand anandamide. 2005 Toxicol. Appl. Pharmacol. pmid:15893538
Quistad GB et al. Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides. 2001 Toxicol. Appl. Pharmacol. pmid:11350214
Kodani SD et al. Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. 2016 Toxicol. Lett. pmid:27659731
Carr RL et al. Effect of developmental chlorpyrifos exposure, on endocannabinoid metabolizing enzymes, in the brain of juvenile rats. 2011 Toxicol. Sci. pmid:21507991
Carr RL et al. Induction of endocannabinoid levels in juvenile rat brain following developmental chlorpyrifos exposure. 2013 Toxicol. Sci. pmid:23761300
Hsu SS et al. Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells. 2007 Toxicology pmid:17222495
Bluett RJ et al. Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation. 2014 Transl Psychiatry pmid:25004388
Leweke FM et al. Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. 2012 Transl Psychiatry pmid:22832859
Maccarrone M et al. Intracellular trafficking of anandamide: new concepts for signaling. 2010 Trends Biochem. Sci. pmid:20570522
Alhouayek M and Muccioli GG The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity. 2012 Trends Mol Med pmid:22917662
Gaetani S et al. Anandamide hydrolysis: a new target for anti-anxiety drugs? 2003 Trends Mol Med pmid:14604824
Maccarrone M Inhibition of anandamide hydrolysis: cells also know how to do it. 2004 Trends Mol Med pmid:14720580
Mechoulam R et al. Cannabinoids and brain injury: therapeutic implications. 2002 Trends Mol Med pmid:11815270
Szallasi A and Di Marzo V New perspectives on enigmatic vanilloid receptors. 2000 Trends Neurosci. pmid:11006466
Devane WA New dawn of cannabinoid pharmacology. 1994 Trends Pharmacol. Sci. pmid:8165721
Zygmunt PM et al. Anandamide - the other side of the coin. 2000 Trends Pharmacol. Sci. pmid:10664604
Smart D and Jerman JC Anandamide: an endogenous activator of the vanilloid receptor. 2000 Trends Pharmacol. Sci. pmid:10740287
Fowler CJ Has FLAT fallen flat? 2014 Trends Pharmacol. Sci. pmid:24398120
Randall MD and Kendall DA Endocannabinoids: a new class of vasoactive substances. 1998 Trends Pharmacol. Sci. pmid:9550942
Di Marzo V et al. Anandamide: some like it hot. 2001 Trends Pharmacol. Sci. pmid:11431028