Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Cough D003371 19 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Edema D004487 152 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Epilepsy D004827 35 associated lipids
Fatty Liver D005234 48 associated lipids
Fever D005334 35 associated lipids
Fibromyalgia D005356 4 associated lipids
Glioma D005910 112 associated lipids
Hepatitis D006505 11 associated lipids
Hyperalgesia D006930 42 associated lipids
Hyperemia D006940 25 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hyperkinesis D006948 11 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypertension D006973 115 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Karbarz MJ et al. Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase. 2009 Anesth. Analg. pmid:19095868
Petrovszki Z et al. The effects of peptide and lipid endocannabinoids on arthritic pain at the spinal level. 2012 Anesth. Analg. pmid:22451592
Romero TR et al. CB1 and CB2 cannabinoid receptor agonists induce peripheral antinociception by activation of the endogenous noradrenergic system. 2013 Anesth. Analg. pmid:23302980
Okura D et al. The endocannabinoid anandamide inhibits voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 in Xenopus oocytes. 2014 Anesth. Analg. pmid:24557103
Farquhar-Smith WP and Rice AS A novel neuroimmune mechanism in cannabinoid-mediated attenuation of nerve growth factor-induced hyperalgesia. 2003 Anesthesiology pmid:14639155
Farquhar-Smith WP and Rice AS Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder. 2001 Anesthesiology pmid:11374613
Schelling G et al. Effects of general anesthesia on anandamide blood levels in humans. 2006 Anesthesiology pmid:16436846
Möhle R et al. Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors. 2001 Ann. N. Y. Acad. Sci. pmid:11458515
Pisani A et al. High endogenous cannabinoid levels in the cerebrospinal fluid of untreated Parkinson's disease patients. 2005 Ann. Neurol. pmid:15852389
Chiurchiù V et al. Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis. 2013 Ann. Neurol. pmid:23447381
Katona I and Freund TF Multiple functions of endocannabinoid signaling in the brain. 2012 Annu. Rev. Neurosci. pmid:22524785
Linsalata M et al. Effects of anandamide on polyamine levels and cell growth in human colon cancer cells. 2010 Anticancer Res. pmid:20682986
Lissoni P et al. The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. 2008 Nov-Dec Anticancer Res. pmid:19189659
Dey R et al. Endocannabinoids inhibit the growth of free-living amoebae. 2010 Antimicrob. Agents Chemother. pmid:20479202
Simpson CD et al. A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance. 2012 Apoptosis pmid:22488300
Fonseca BM et al. The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation. 2013 Apoptosis pmid:24048885
Pinar-Sueiro S et al. [Cannabinoid applications in glaucoma]. 2011 Arch Soc Esp Oftalmol pmid:21414525
Fowler CJ et al. Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen. 1999 Arch. Biochem. Biophys. pmid:9989926
Maccarrone M et al. Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes. 2001 Arch. Biochem. Biophys. pmid:11556820
Oz M et al. Effects of saturated long-chain N-acylethanolamines on voltage-dependent Ca2+ fluxes in rabbit T-tubule membranes. 2005 Arch. Biochem. Biophys. pmid:15639235