Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Cough D003371 19 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Edema D004487 152 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Epilepsy D004827 35 associated lipids
Fatty Liver D005234 48 associated lipids
Fever D005334 35 associated lipids
Fibromyalgia D005356 4 associated lipids
Glioma D005910 112 associated lipids
Hepatitis D006505 11 associated lipids
Hyperalgesia D006930 42 associated lipids
Hyperemia D006940 25 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hyperkinesis D006948 11 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypertension D006973 115 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Ferrer B et al. Regulation of brain anandamide by acute administration of ethanol. 2007 Biochem. J. pmid:17302558
Di Marzo V et al. Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. 1996 Biochem. J. pmid:8670178
Bisogno T et al. N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo. 2000 Biochem. J. pmid:11042139
Sun YX et al. Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D. 2004 Biochem. J. pmid:14998370
Ligresti A et al. Further evidence for the existence of a specific process for the membrane transport of anandamide. 2004 Biochem. J. pmid:14969584
Bisogno T et al. Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. 1997 Biochem. J. pmid:9065792
Maccarrone M et al. Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells. 2002 Biochem. J. pmid:12010121
Bornheim LM et al. Microsomal cytochrome P450-mediated liver and brain anandamide metabolism. 1995 Biochem. Pharmacol. pmid:7669071
Childers SR et al. Effects of anandamide on cannabinoid receptors in rat brain membranes. 1994 Biochem. Pharmacol. pmid:8129747
Fowler CJ and Tiger G Cyclooxygenation of the arachidonoyl side chain of 1-arachidonoylglycerol and related compounds block their ability to prevent anandamide and 2-oleoylglycerol metabolism by rat brain in vitro. 2005 Biochem. Pharmacol. pmid:15794945
Fowler CJ et al. Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. 2001 Biochem. Pharmacol. pmid:11585048
Shivachar AC Cannabinoids inhibit sodium-dependent, high-affinity excitatory amino acid transport in cultured rat cortical astrocytes. 2007 Biochem. Pharmacol. pmid:17445778
Hansen HS and Diep TA N-acylethanolamines, anandamide and food intake. 2009 Biochem. Pharmacol. pmid:19413995
Shivachar AC et al. Anandamide- and delta9-tetrahydrocannabinol-evoked arachidonic acid mobilization and blockade by SR141716A [N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4 -methyl-1H-pyrazole-3-carboximide hydrochloride]. 1996 Biochem. Pharmacol. pmid:8615904
Burstein SH et al. Regulation of anandamide tissue levels by N-arachidonylglycine. 2002 Biochem. Pharmacol. pmid:12234618
Guzmán M et al. Effects of anandamide on hepatic fatty acid metabolism. 1995 Biochem. Pharmacol. pmid:7575652
Mechoulam R et al. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. 1995 Biochem. Pharmacol. pmid:7605349
Yang Z et al. Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine. 2008 Biochem. Pharmacol. pmid:18755158
Correa F et al. A role for CB2 receptors in anandamide signalling pathways involved in the regulation of IL-12 and IL-23 in microglial cells. 2009 Biochem. Pharmacol. pmid:18848818
Fernández-Ruiz JJ et al. Time course of the effects of different cannabimimetics on prolactin and gonadotrophin secretion: evidence for the presence of CB1 receptors in hypothalamic structures and their involvement in the effects of cannabimimetics. 1997 Biochem. Pharmacol. pmid:9256167