Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Weight Gain D015430 101 associated lipids
Hyperemia D006940 25 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Glioma D005910 112 associated lipids
Obesity D009765 29 associated lipids
Bradycardia D001919 13 associated lipids
Urinary Bladder Diseases D001745 4 associated lipids
Alzheimer Disease D000544 76 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Neuroblastoma D009447 66 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Nervous System Diseases D009422 37 associated lipids
Ataxia D001259 20 associated lipids
Brain Edema D001929 20 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Milton NG Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. 2002 Neurosci. Lett. pmid:12384227
Krylatov AV et al. Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism. 2002 Bull. Exp. Biol. Med. pmid:12428277
Plant LD et al. Hypoxic depolarization of cerebellar granule neurons by specific inhibition of TASK-1. 2002 Stroke pmid:12215606
Randall MD et al. Cardiovascular effects of cannabinoids. 2002 Pharmacol. Ther. pmid:12182966
Kagaya M et al. Characterization of the anandamide induced depolarization of guinea-pig isolated vagus nerve. 2002 Br. J. Pharmacol. pmid:12183329
Ishii I and Chun J Anandamide-induced neuroblastoma cell rounding via the CB1 cannabinoid receptors. 2002 Neuroreport pmid:11973452
Geraghty DP and Mazzone SB Respiratory actions of vanilloid receptor agonists in the nucleus of the solitary tract: comparison of resiniferatoxin with non-pungent agents and anandamide. 2002 Br. J. Pharmacol. pmid:12411424
Maingret F et al. The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1. 2001 EMBO J. pmid:11226154
Izzo AA et al. Effect of vanilloid drugs on gastrointestinal transit in mice. 2001 Br. J. Pharmacol. pmid:11264233
Baker D et al. Endocannabinoids control spasticity in a multiple sclerosis model. 2001 FASEB J. pmid:11156943
Gauldie SD et al. Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints. 2001 Br. J. Pharmacol. pmid:11159713
Tognetto M et al. Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation. 2001 J. Neurosci. pmid:11160380
MacCarrone M et al. Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor. 2001 Eur. J. Biochem. pmid:11168423
Hansen HH et al. Accumulation of the anandamide precursor and other N-acylethanolamine phospholipids in infant rat models of in vivo necrotic and apoptotic neuronal death. 2001 J. Neurochem. pmid:11145976
Matias I et al. Evidence for an endocannabinoid system in the central nervous system of the leech Hirudo medicinalis. 2001 Brain Res. Mol. Brain Res. pmid:11245916
Kurihara J et al. 2-Arachidonoylglycerol and anandamide oppositely modulate norepinephrine release from the rat heart sympathetic nerves. 2001 Jpn. J. Pharmacol. pmid:11676206
Nogueron MI et al. Cannabinoid receptor agonists inhibit depolarization-induced calcium influx in cerebellar granule neurons. 2001 J. Neurochem. pmid:11677265
van der Stelt M et al. Exogenous anandamide protects rat brain against acute neuronal injury in vivo. 2001 J. Neurosci. pmid:11698588
Rodríguez de Fonseca F et al. An anorexic lipid mediator regulated by feeding. 2001 Nature pmid:11700558
Jamshidi N and Taylor DA Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. 2001 Br. J. Pharmacol. pmid:11704633
Jonsson KO et al. Effects of homologues and analogues of palmitoylethanolamide upon the inactivation of the endocannabinoid anandamide. 2001 Br. J. Pharmacol. pmid:11498512
Hayase T et al. Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity. 2001 Nihon Arukoru Yakubutsu Igakkai Zasshi pmid:11828716
Al-Hayani A et al. The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice. 2001 Neuropharmacology pmid:11747904
Izzo AA et al. The gastrointestinal pharmacology of cannabinoids. 2001 Curr Opin Pharmacol pmid:11757815
Kagota S et al. 2-Arachidonoylglycerol, a candidate of endothelium-derived hyperpolarizing factor. 2001 Eur. J. Pharmacol. pmid:11275004
Bisogno T et al. The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors. 2001 Eur. J. Biochem. pmid:11277920
De Petrocellis L et al. The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism. 2001 J. Biol. Chem. pmid:11278420
Jacobsson SO and Fowler CJ Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide. 2001 Br. J. Pharmacol. pmid:11309246
Quistad GB et al. Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides. 2001 Toxicol. Appl. Pharmacol. pmid:11350214
Day TA et al. Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide. 2001 Mol. Pharmacol. pmid:11353795
Kobayashi Y et al. Activation by 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, of p42/44 mitogen-activated protein kinase in HL-60 cells. 2001 J. Biochem. pmid:11328586
Chang YH et al. Effects of cannabinoids on LPS-stimulated inflammatory mediator release from macrophages: involvement of eicosanoids. 2001 J. Cell. Biochem. pmid:11329626
Olah Z et al. Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1. 2001 J. Biol. Chem. pmid:11333266
Calignano A et al. Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. 2001 Eur. J. Pharmacol. pmid:11426841
Fride E et al. Critical role of the endogenous cannabinoid system in mouse pup suckling and growth. 2001 Eur. J. Pharmacol. pmid:11426843
Murillo-Rodríguez E et al. Anandamide-induced sleep is blocked by SR141716A, a CB1 receptor antagonist and by U73122, a phospholipase C inhibitor. 2001 Neuroreport pmid:11447321
Sprague J et al. Temperature-dependent activation of recombinant rat vanilloid VR1 receptors expressed in HEK293 cells by capsaicin and anandamide. 2001 Eur. J. Pharmacol. pmid:11448475
Porter AC and Felder CC The endocannabinoid nervous system: unique opportunities for therapeutic intervention. 2001 Pharmacol. Ther. pmid:11448725
Laine K et al. Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits. 2001 Pharm. Res. pmid:11451037
Holt S et al. Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen. 2001 Br. J. Pharmacol. pmid:11399668
Di Marzo V et al. Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues. 2001 Eur. J. Pharmacol. pmid:11408034
Breivogel CS et al. Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. 2001 Mol. Pharmacol. pmid:11408610
Wang Y et al. Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. 2001 Anal. Biochem. pmid:11412008
De Petrocellis L et al. The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase. 2001 J. Neurochem. pmid:11413249
Morisset V and Urban L Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord. 2001 J. Neurophysiol. pmid:11431486
Bátkai S et al. Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. 2001 Nat. Med. pmid:11433348
Maccarrone M et al. Progesterone up-regulates anandamide hydrolase in human lymphocytes: role of cytokines and implications for fertility. 2001 J. Immunol. pmid:11390466
Wenger T et al. The central cannabinoid receptor inactivation suppresses endocrine reproductive functions. 2001 Biochem. Biophys. Res. Commun. pmid:11394887
Maccarrone M et al. Gas chromatography-mass spectrometry analysis of endogenous cannabinoids in healthy and tumoral human brain and human cells in culture. 2001 J. Neurochem. pmid:11208922
Berdyshev EV et al. Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2-AG) in immune cells. 2001 FASEB J. pmid:11641243