Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Peptic Ulcer D010437 19 associated lipids
Ataxia D001259 20 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Brain Edema D001929 20 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Breast Neoplasms D001943 24 associated lipids
Hyperemia D006940 25 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Hyperinsulinism D006946 27 associated lipids
Endotoxemia D019446 27 associated lipids
Neuralgia D009437 28 associated lipids
Obesity D009765 29 associated lipids
Catalepsy D002375 30 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Memory Disorders D008569 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Fever D005334 35 associated lipids
Epilepsy D004827 35 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Hypotension D007022 41 associated lipids
Hyperalgesia D006930 42 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Fatty Liver D005234 48 associated lipids
Nerve Degeneration D009410 53 associated lipids
Pain D010146 64 associated lipids
Reperfusion Injury D015427 65 associated lipids
Neuroblastoma D009447 66 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Colitis D003092 69 associated lipids
Melanoma D008545 69 associated lipids
Stomach Ulcer D013276 75 associated lipids
Alzheimer Disease D000544 76 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Gain D015430 101 associated lipids
Glioma D005910 112 associated lipids
Hypertension D006973 115 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Salzet M et al. Leech immunocytes contain proopiomelanocortin: nitric oxide mediates hemolymph proopiomelanocortin processing. 1997 J. Immunol. pmid:9548480
Randall MD and Kendall DA Endocannabinoids: a new class of vasoactive substances. 1998 Trends Pharmacol. Sci. pmid:9550942
Kimura T et al. Anandamide, an endogenous cannabinoid receptor ligand, also interacts with 5-hydroxytryptamine (5-HT) receptor. 1998 Biol. Pharm. Bull. pmid:9556149
Soderstrom K et al. Discovery of novel cannabinoid receptor ligands from diverse marine organisms. 1997 Adv. Exp. Med. Biol. pmid:9561107
Qureshi J et al. Identification and characterization of a novel synthetic cannabinoid CP 55,940 binder in rat brain cytosol. 1998 Mol. Cell. Biochem. pmid:9562238
Derocq JM et al. The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor-independent pathway in hematopoietic cell lines. 1998 FEBS Lett. pmid:9563506
Axelrod J and Felder CC Cannabinoid receptors and their endogenous agonist, anandamide. 1998 Neurochem. Res. pmid:9566594
Prevot V et al. Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: neurovascular regulation. 1998 Brain Res. pmid:9593913
Richardson JD et al. Antihyperalgesic effects of spinal cannabinoids. 1998 Eur. J. Pharmacol. pmid:9600630
Stefano GB Autoimmunovascular regulation: morphine and anandamide and ancondamide stimulated nitric oxide release. 1998 J. Neuroimmunol. pmid:9610675
Smith FL et al. Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats. 1998 Pharmacol. Biochem. Behav. pmid:9610941
Gurwitz D and Kloog Y Do endogenous cannabinoids contribute to HIV-mediated immune failure? 1998 Mol Med Today pmid:9612798
Randall MD and Kendall DA Anandamide and endothelium-derived hyperpolarizing factor act via a common vasorelaxant mechanism in rat mesentery. 1998 Eur. J. Pharmacol. pmid:9617751
Paria BC et al. Effects of cannabinoids on preimplantation mouse embryo development and implantation are mediated by brain-type cannabinoid receptors. 1998 Biol. Reprod. pmid:9623610
Di Marzo V 'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance. 1998 Biochim. Biophys. Acta pmid:9630590
Stefano GB et al. Anandamide amidase inhibition enhances anandamide-stimulated nitric oxide release in invertebrate neural tissues. 1998 Brain Res. pmid:9630717
Schmid PC et al. Alternative pathways of anandamide biosynthesis in rat testes. 1998 Chem. Phys. Lipids pmid:9631536
Kondo S et al. Accumulation of various N-acylethanolamines including N-arachidonoylethanolamine (anandamide) in cadmium chloride-administered rat testis. 1998 Arch. Biochem. Biophys. pmid:9637740
Stefano GB et al. Antagonism of LPS and IFN-gamma induction of iNOS in human saphenous vein endothelium by morphine and anandamide by nitric oxide inhibition of adenylate cyclase. 1998 J. Cardiovasc. Pharmacol. pmid:9641464
Stefano GB et al. Long-term exposure of human blood vessels to HIV gp120, morphine, and anandamide increases endothelial adhesion of monocytes: uncoupling of nitric oxide release. 1998 J. Cardiovasc. Pharmacol. pmid:9641470
Mallet PE and Beninger RJ Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. 1998 Life Sci. pmid:9651110
De Petrocellis L et al. The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9653194
Edgemond WS et al. Human platelets and polymorphonuclear leukocytes synthesize oxygenated derivatives of arachidonylethanolamide (anandamide): their affinities for cannabinoid receptors and pathways of inactivation. 1998 Mol. Pharmacol. pmid:9658204
Patel NA et al. Arachidonylethanolamide (AEA) activation of FOS proto-oncogene protein immunoreactivity in the rat brain. 1998 Brain Res. pmid:9666136
van Zadelhoff G et al. With anandamide as substrate plant 5-lipoxygenases behave like 11-lipoxygenases. 1998 Biochem. Biophys. Res. Commun. pmid:9675081
Qin C et al. Determination of anandamide amidase activity using ultraviolet-active amine derivatives and reverse-phase high-performance liquid chromatography. 1998 Anal. Biochem. pmid:9683506
Calignano A et al. Control of pain initiation by endogenous cannabinoids. 1998 Nature pmid:9685157
Stefano GB et al. Macrophage behavior associated with acute and chronic exposure to HIV GP120, morphine and anandamide: endothelial implications. 1998 Int. J. Cardiol. pmid:9687087
Bisogno T et al. Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation. 1998 Eur. J. Biochem. pmid:9688276
Jaggar SI et al. The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. 1998 Pain pmid:9696473
Bisogno T et al. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. 1998 Biochem. Biophys. Res. Commun. pmid:9703957
Varga K et al. Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. 1998 FASEB J. pmid:9707176
Childers SR and Breivogel CS Cannabis and endogenous cannabinoid systems. 1998 Jun-Jul Drug Alcohol Depend pmid:9716939
Berdyshev E et al. Effects of cannabinoid receptor ligands on LPS-induced pulmonary inflammation in mice. 1998 Life Sci. pmid:9718090
Fulton D and Quilley J Evidence against anandamide as the hyperpolarizing factor mediating the nitric oxide-independent coronary vasodilator effect of bradykinin in the rat. 1998 J. Pharmacol. Exp. Ther. pmid:9732371
Welch SP et al. Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A. 1998 J. Pharmacol. Exp. Ther. pmid:9732392
Fields HL and Meng ID Watching the pot boil. 1998 Nat. Med. pmid:9734389
Molina-Holgado F et al. The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway. 1998 FEBS Lett. pmid:9738948
McGregor IS et al. A comparison of delta 9-THC and anandamide induced c-fos expression in the rat forebrain. 1998 Brain Res. pmid:9748483
Schneider U et al. Cannabinoid/anandamide system and schizophrenia: is there evidence for association? 1998 Pharmacopsychiatry pmid:9754842
Stengel PW et al. Pulmonary actions of anandamide, an endogenous cannabinoid receptor agonist, in guinea pigs. 1998 Eur. J. Pharmacol. pmid:9754939
Wiley JL et al. Evaluation of cannabimimetic effects of structural analogs of anandamide in rats. 1998 Eur. J. Pharmacol. pmid:9760024
Jaggar SI et al. The endogenous cannabinoid anandamide, but not the CB2 ligand palmitoylethanolamide, prevents the viscero-visceral hyper-reflexia associated with inflammation of the rat urinary bladder. 1998 Neurosci. Lett. pmid:9774165
Tong W et al. Derivation of a pharmacophore model for anandamide using constrained conformational searching and comparative molecular field analysis. 1998 J. Med. Chem. pmid:9784095
Pestonjamasp VK and Burstein SH Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system. 1998 Biochim. Biophys. Acta pmid:9795237
Lichtman AH et al. Effects of SR 141716A after acute or chronic cannabinoid administration in dogs. 1998 Eur. J. Pharmacol. pmid:9797029
Di Marzo V et al. Interactions between synthetic vanilloids and the endogenous cannabinoid system. 1998 FEBS Lett. pmid:9801167
Stein EA et al. Selective effects of the endogenous cannabinoid arachidonylethanolamide (anandamide) on regional cerebral blood flow in the rat. 1998 Neuropsychopharmacology pmid:9803424
White R and Hiley CR The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery. 1998 Br. J. Pharmacol. pmid:9806337
Levin M and Mercola M Gap junctions are involved in the early generation of left-right asymmetry. 1998 Dev. Biol. pmid:9806775