Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Levin M and Mercola M | Expression of connexin 30 in Xenopus embryos and its involvement in hatching gland function. | 2000 | Dev. Dyn. | pmid:10974676 |
Sinor AD et al. | Endocannabinoids protect cerebral cortical neurons from in vitro ischemia in rats. | 2000 | Neurosci. Lett. | pmid:10653017 |
Di Marzo V et al. | Enhancement of anandamide formation in the limbic forebrain and reduction of endocannabinoid contents in the striatum of delta9-tetrahydrocannabinol-tolerant rats. | 2000 | J. Neurochem. | pmid:10737621 |
Smart D and Jerman JC | Anandamide: an endogenous activator of the vanilloid receptor. | 2000 | Trends Pharmacol. Sci. | pmid:10740287 |
Beltramo M et al. | Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitor. | 2000 | J. Neurosci. | pmid:10777802 |
Gonsiorek W et al. | Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide. | 2000 | Mol. Pharmacol. | pmid:10779390 |
Calignano A et al. | Bidirectional control of airway responsiveness by endogenous cannabinoids. | 2000 | Nature | pmid:11081515 |
Reggio PH and Traore H | Conformational requirements for endocannabinoid interaction with the cannabinoid receptors, the anandamide transporter and fatty acid amidohydrolase. | 2000 | Chem. Phys. Lipids | pmid:11106780 |
Howlett AC and Mukhopadhyay S | Cellular signal transduction by anandamide and 2-arachidonoylglycerol. | 2000 | Chem. Phys. Lipids | pmid:11106782 |
Schmid HH | Pathways and mechanisms of N-acylethanolamine biosynthesis: can anandamide be generated selectively? | 2000 | Chem. Phys. Lipids | pmid:11106783 |
Fichera M et al. | A 3D-QSAR study on the structural requirements for binding to CB(1) and CB(2) cannabinoid receptors. | 2000 | J. Med. Chem. | pmid:10882356 |
Schmid PC et al. | A sensitive endocannabinoid assay. The simultaneous analysis of N-acylethanolamines and 2-monoacylglycerols. | 2000 | Chem. Phys. Lipids | pmid:10669310 |
Griffin G et al. | Cloning and pharmacological characterization of the rat CB(2) cannabinoid receptor. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688601 |
Rakhshan F et al. | Carrier-mediated uptake of the endogenous cannabinoid anandamide in RBL-2H3 cells. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688610 |
De Petrocellis L et al. | Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid receptor: inhibitors of anandamide uptake with negligible capsaicin-like activity. | 2000 | FEBS Lett. | pmid:11033355 |
Arai Y et al. | Sensitive determination of anandamide in rat brain utilizing a coupled-column HPLC with fluorimetric detection. | 2000 | Biomed. Chromatogr. | pmid:10694706 |
Bannerman P et al. | Early migratory rat neural crest cells express functional gap junctions: evidence that neural crest cell survival requires gap junction function. | 2000 | J. Neurosci. Res. | pmid:10972957 |
Premkumar LS and Ahern GP | Induction of vanilloid receptor channel activity by protein kinase C. | 2000 Dec 21-28 | Nature | pmid:11140687 |
Hungund BL and Basavarajappa BS | Are anandamide and cannabinoid receptors involved in ethanol tolerance? A review of the evidence. | 2000 Mar-Apr | Alcohol Alcohol. | pmid:10787386 |
Maingret F et al. | The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1. | 2001 | EMBO J. | pmid:11226154 |
Karava V et al. | Anandamide amidohydrolase activity, released in the medium by Tetrahymena pyriformis. Identification and partial characterization. | 2001 | FEBS Lett. | pmid:11728445 |
Stamer WD et al. | Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues. | 2001 | Eur. J. Pharmacol. | pmid:11730719 |
Hayase T et al. | Protective effects of cannabinoid receptor agonists against cocaine and other convulsant-induced toxic behavioural symptoms. | 2001 | J. Pharm. Pharmacol. | pmid:11732755 |
Hansen HH et al. | Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration. | 2001 | J. Neurochem. | pmid:11579150 |
Smith PJ and McQueen DS | Anandamide induces cardiovascular and respiratory reflexes via vasosensory nerves in the anaesthetized rat. | 2001 | Br. J. Pharmacol. | pmid:11588121 |
Maccarrone M et al. | Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes. | 2001 | Arch. Biochem. Biophys. | pmid:11556820 |
Crozier Willi G et al. | Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods. | 2001 | Nestle Nutr Workshop Ser Clin Perform Programme | pmid:11510437 |
Stella N and Piomelli D | Receptor-dependent formation of endogenous cannabinoids in cortical neurons. | 2001 | Eur. J. Pharmacol. | pmid:11513837 |
Vellani V et al. | Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide. | 2001 | J. Physiol. (Lond.) | pmid:11483711 |
Maccarrone M et al. | Anandamide degradation and N-acylethanolamines level in wild-type and CB1 cannabinoid receptor knockout mice of different ages. | 2001 | J. Neurochem. | pmid:11461969 |
Ueda N et al. | Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance. | 2001 | J. Biol. Chem. | pmid:11463796 |
López-RodrÃguez ML et al. | Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors. | 2001 | J. Med. Chem. | pmid:11741470 |
Chemin J et al. | Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide. | 2001 | EMBO J. | pmid:11742980 |
Bifulco M et al. | Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth. | 2001 | FASEB J. | pmid:11687506 |
De Petrocellis L et al. | Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors. | 2001 | FEBS Lett. | pmid:11602256 |
Bisogno T et al. | Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. | 2001 | Br. J. Pharmacol. | pmid:11606325 |
D'Souza DC and Kosten TR | Cannabinoid antagonists: a treatment in search of an illness. | 2001 | Arch. Gen. Psychiatry | pmid:11296092 |
Murillo-RodrÃguez E et al. | Anandamide-induced sleep is blocked by SR141716A, a CB1 receptor antagonist and by U73122, a phospholipase C inhibitor. | 2001 | Neuroreport | pmid:11447321 |
Sprague J et al. | Temperature-dependent activation of recombinant rat vanilloid VR1 receptors expressed in HEK293 cells by capsaicin and anandamide. | 2001 | Eur. J. Pharmacol. | pmid:11448475 |
Porter AC and Felder CC | The endocannabinoid nervous system: unique opportunities for therapeutic intervention. | 2001 | Pharmacol. Ther. | pmid:11448725 |
Laine K et al. | Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits. | 2001 | Pharm. Res. | pmid:11451037 |
Holt S et al. | Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen. | 2001 | Br. J. Pharmacol. | pmid:11399668 |
Di Marzo V et al. | Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues. | 2001 | Eur. J. Pharmacol. | pmid:11408034 |
Breivogel CS et al. | Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. | 2001 | Mol. Pharmacol. | pmid:11408610 |
Wang Y et al. | Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. | 2001 | Anal. Biochem. | pmid:11412008 |
De Petrocellis L et al. | The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase. | 2001 | J. Neurochem. | pmid:11413249 |
Morisset V and Urban L | Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord. | 2001 | J. Neurophysiol. | pmid:11431486 |
Bátkai S et al. | Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. | 2001 | Nat. Med. | pmid:11433348 |
Maccarrone M et al. | Progesterone up-regulates anandamide hydrolase in human lymphocytes: role of cytokines and implications for fertility. | 2001 | J. Immunol. | pmid:11390466 |
Berdyshev EV et al. | Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2-AG) in immune cells. | 2001 | FASEB J. | pmid:11641243 |