Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Ozalp A and Barroso B | Simultaneous quantitative analysis of N-acylethanolamides in clinical samples. | 2009 | Anal. Biochem. | pmid:19665986 |
Catanzaro G et al. | Anandamide increases swelling and reduces calcium sensitivity of mitochondria. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19679102 |
Fraga D et al. | Endogenous cannabinoids induce fever through the activation of CB1 receptors. | 2009 | Br. J. Pharmacol. | pmid:19681872 |
Lozovaya N et al. | Dual modulation of CNS voltage-gated calcium channels by cannabinoids: Focus on CB1 receptor-independent effects. | 2009 | Cell Calcium | pmid:19682741 |
McCue JM et al. | In vitro synthesis of arachidonoyl amino acids by cytochrome c. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19683594 |
GarcÃa-GarcÃa F et al. | Sleep-inducing factors. | 2009 | CNS Neurol Disord Drug Targets | pmid:19689305 |
Barana A et al. | Endocannabinoids and cannabinoid analogues block cardiac hKv1.5 channels in a cannabinoid receptor-independent manner. | 2010 | Cardiovasc. Res. | pmid:19689982 |
Pasquariello N et al. | Characterization of the endocannabinoid system in human neuronal cells and proteomic analysis of anandamide-induced apoptosis. | 2009 | J. Biol. Chem. | pmid:19690173 |
Jean-Gilles L et al. | Plasma endocannabinoid levels in multiple sclerosis. | 2009 | J. Neurol. Sci. | pmid:19695579 |
Gardiner SM et al. | Factors influencing the regional haemodynamic responses to methanandamide and anandamide in conscious rats. | 2009 | Br. J. Pharmacol. | pmid:19702785 |
Hill MN et al. | Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis. | 2009 | Neuropsychopharmacology | pmid:19710634 |
Yusifzade K et al. | The protective role of anandamide in mesenteric ischemia reperfusion injury in guinea pig. | 2009 | Bratisl Lek Listy | pmid:19711821 |
Thors L and Fowler CJ | Effect of nitric oxide donors on membrane tritium accumulation of endocannabinoids and related endogenous lipids. | 2009 | Eur. J. Pharmacol. | pmid:19715690 |
Wyffels L et al. | Synthesis, in vitro and in vivo evaluation, and radiolabeling of aryl anandamide analogues as candidate radioligands for in vivo imaging of fatty acid amide hydrolase in the brain. | 2009 | J. Med. Chem. | pmid:19719235 |
Kaufmann I et al. | Enhanced anandamide plasma levels in patients with complex regional pain syndrome following traumatic injury: a preliminary report. | 2009 | Eur Surg Res | pmid:19729930 |
Shinohara Y et al. | Cannabinoid in the nucleus accumbens enhances the intake of palatable solution. | 2009 | Neuroreport | pmid:19734811 |
Campos AC and Guimarães FS | Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. | 2009 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:19735690 |
Di Marzo V et al. | Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects. | 2009 | Eur. J. Endocrinol. | pmid:19745037 |
Schroeder C et al. | Circulating endocannabinoid concentrations during orthostatic stress. | 2009 | Clin. Auton. Res. | pmid:19756829 |
Cano C et al. | Synthesis and pharmacological evaluation of sulfamide-based analogues of anandamide. | 2009 | Eur J Med Chem | pmid:19762126 |
Centonze D et al. | Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis. | 2009 | Neurol. Sci. | pmid:19768368 |
Piccinetti CC et al. | Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish. | 2010 | Gen. Comp. Endocrinol. | pmid:19800340 |
Romigi A et al. | Cerebrospinal fluid levels of the endocannabinoid anandamide are reduced in patients with untreated newly diagnosed temporal lobe epilepsy. | 2010 | Epilepsia | pmid:19817812 |
Abalo R et al. | Postnatal maturation of the gastrointestinal tract: a functional and immunohistochemical study in the guinea-pig ileum at weaning. | 2009 | Neurosci. Lett. | pmid:19819299 |
Guindon J and Hohmann AG | The endocannabinoid system and pain. | 2009 | CNS Neurol Disord Drug Targets | pmid:19839937 |
Caraceni P et al. | Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. | 2010 | Liver Int. | pmid:19840245 |
Mendiguren A and Pineda J | Effect of the CB(1) receptor antagonists rimonabant and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices. | 2009 | Br. J. Pharmacol. | pmid:19845674 |
Fonseca BM et al. | Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: evidence for a role of the endocannabinoid system during the period of placental development. | 2009 | Reprod. Biol. Endocrinol. | pmid:19860893 |
Ziegler CG et al. | Expression and function of endocannabinoid receptors in the human adrenal cortex. | 2010 | Horm. Metab. Res. | pmid:19862666 |
Buznikov GA et al. | A putative 'pre-nervous' endocannabinoid system in early echinoderm development. | 2010 | Dev. Neurosci. | pmid:19907129 |
Long JZ et al. | Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19918051 |
Kaczocha M et al. | Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2. | 2010 | J. Biol. Chem. | pmid:19926788 |
Marco EM and Viveros MP | The critical role of the endocannabinoid system in emotional homeostasis: avoiding excess and deficiencies. | 2009 | Mini Rev Med Chem | pmid:19929814 |
Weis F et al. | Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. | 2010 | J. Mol. Cell. Cardiol. | pmid:19931541 |
Catani MV et al. | Anandamide extends platelets survival through CB(1)-dependent Akt signaling. | 2010 | Cell. Mol. Life Sci. | pmid:19936621 |
Aquila S et al. | Human sperm anatomy: ultrastructural localization of the cannabinoid1 receptor and a potential role of anandamide in sperm survival and acrosome reaction. | 2010 | Anat Rec (Hoboken) | pmid:19938110 |
Wiley JL and Burston JJ | Chronic Delta9-tetrahydrocannabinol during adolescence increases sensitivity to subsequent cannabinoid effects in delayed nonmatch-to-position in rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:19941884 |
Mukhopadhyay P et al. | CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes. | 2010 | Cardiovasc. Res. | pmid:19942623 |
Banni S and Di Marzo V | Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. | 2010 | Mol Nutr Food Res | pmid:20013888 |
Guindon J and Beaulieu P | The role of the endogenous cannabinoid system in peripheral analgesia. | 2009 | Curr Mol Pharmacol | pmid:20021453 |
Marczylo TH et al. | Anandamide levels in human female reproductive tissues: solid-phase extraction and measurement by ultraperformance liquid chromatography tandem mass spectrometry. | 2010 | Anal. Biochem. | pmid:20026294 |
Touriño C et al. | FAAH deficiency promotes energy storage and enhances the motivation for food. | 2010 | Int J Obes (Lond) | pmid:20029375 |
Pamplona FA et al. | Aspirin-triggered lipoxin induces CB1-dependent catalepsy in mice. | 2010 | Neurosci. Lett. | pmid:20036315 |
Li Q et al. | Electrophysiological effects of anandamide on rat myocardium. | 2009 | Br. J. Pharmacol. | pmid:20050190 |
Oz M et al. | The endogenous cannabinoid, anandamide, inhibits dopamine transporter function by a receptor-independent mechanism. | 2010 | J. Neurochem. | pmid:20050977 |
Herrera-SolÃs A et al. | Acute and subchronic administration of anandamide or oleamide increases REM sleep in rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:20056119 |
Yang Q et al. | Anandamide induces cell death through lipid rafts in hepatic stellate cells. | 2010 | J. Gastroenterol. Hepatol. | pmid:20059638 |
Sang N et al. | Anandamide potentiation of miniature spontaneous excitatory synaptic transmission is mediated via IP3 pathway. | 2010 | Neurochem. Int. | pmid:20064571 |
Aquila S et al. | Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm. | 2010 | Br. J. Pharmacol. | pmid:20067470 |
Yoshida R et al. | Endocannabinoids selectively enhance sweet taste. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20080779 |
Ribeiro A et al. | Anandamide prior to sensitization increases cell-mediated immunity in mice. | 2010 | Int. Immunopharmacol. | pmid:20093200 |
Cencioni MT et al. | Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors. | 2010 | PLoS ONE | pmid:20098669 |
Zakrzeska A et al. | A cannabinoid receptor, sensitive to O-1918, is involved in the delayed hypotension induced by anandamide in anaesthetized rats. | 2010 | Br. J. Pharmacol. | pmid:20105178 |
Johannesson M et al. | Cloning, purification and characterization of non-human primate 12/15-lipoxygenases. | 2010 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20106647 |
Izzo AA and Sharkey KA | Cannabinoids and the gut: new developments and emerging concepts. | 2010 | Pharmacol. Ther. | pmid:20117132 |
Snider NT et al. | Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by the cytochrome P450 monooxygenases: physiological and pharmacological implications. | 2010 | Pharmacol. Rev. | pmid:20133390 |
Moreno-Galindo EG et al. | Molecular basis for a high-potency open-channel block of Kv1.5 channel by the endocannabinoid anandamide. | 2010 | Mol. Pharmacol. | pmid:20133392 |
Onnis V et al. | Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors. | 2010 | J. Med. Chem. | pmid:20143779 |
Bhaskaran MD and Smith BN | Effects of TRPV1 activation on synaptic excitation in the dentate gyrus of a mouse model of temporal lobe epilepsy. | 2010 | Exp. Neurol. | pmid:20144892 |
Lerner TN et al. | Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. | 2010 | J. Neurosci. | pmid:20147543 |
Ueda N et al. | N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA). | 2010 | Prog. Lipid Res. | pmid:20152858 |
Tanimura A et al. | The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission. | 2010 | Neuron | pmid:20159446 |
Reggio PH | Endocannabinoid binding to the cannabinoid receptors: what is known and what remains unknown. | 2010 | Curr. Med. Chem. | pmid:20166921 |
Di Marzo V and De Petrocellis L | Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs. | 2010 | Curr. Med. Chem. | pmid:20166923 |
Alptekin A et al. | The effects of anandamide transport inhibitor AM404 on voltage-dependent calcium channels. | 2010 | Eur. J. Pharmacol. | pmid:20171208 |
Solinas M et al. | Dopaminergic augmentation of delta-9-tetrahydrocannabinol (THC) discrimination: possible involvement of D(2)-induced formation of anandamide. | 2010 | Psychopharmacology (Berl.) | pmid:20179908 |
Rueda-Orozco PE et al. | Intrahippocampal administration of anandamide increases REM sleep. | 2010 | Neurosci. Lett. | pmid:20188142 |
Malinowska B et al. | Involvement of central beta2-adrenergic, NMDA and thromboxane A2 receptors in the pressor effect of anandamide in rats. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20198363 |
De Laurentiis A et al. | The hypothalamic endocannabinoid system participates in the secretion of oxytocin and tumor necrosis factor-alpha induced by lipopolysaccharide. | 2010 | J. Neuroimmunol. | pmid:20207018 |
Kobayashi N and Yamamoto Y | Hypoxic responses of arterial chemoreceptors in rabbits are primarily mediated by leak K channels. | 2010 | Adv. Exp. Med. Biol. | pmid:20217348 |
Roser P et al. | Potential antipsychotic properties of central cannabinoid (CB1) receptor antagonists. | 2010 | World J. Biol. Psychiatry | pmid:20218784 |
Musella A et al. | Transient receptor potential vanilloid 1 channels control acetylcholine/2-arachidonoylglicerol coupling in the striatum. | 2010 | Neuroscience | pmid:20219639 |
Makwana R et al. | Pharmacological characterization of cannabinoid receptor activity in the rat-isolated ileum myenteric plexus-longitudinal muscle preparation. | 2010 | Br. J. Pharmacol. | pmid:20233228 |
Kozono S et al. | Involvement of the endocannabinoid system in periodontal healing. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20233580 |
Muccioli GG | Endocannabinoid biosynthesis and inactivation, from simple to complex. | 2010 | Drug Discov. Today | pmid:20304091 |
Laezza C et al. | Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and of Ras farnesylation mediate antitumor effects of anandamide in human breast cancer cells. | 2010 | Endocr. Relat. Cancer | pmid:20304978 |
Morera-Herreras T et al. | Regulation of subthalamic neuron activity by endocannabinoids. | 2010 | Synapse | pmid:20336631 |
Ali AB and Todorova M | Asynchronous release of GABA via tonic cannabinoid receptor activation at identified interneuron synapses in rat CA1. | 2010 | Eur. J. Neurosci. | pmid:20345910 |
Frampton G et al. | Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling. | 2010 | Exp. Cell Res. | pmid:20347808 |
Kim J and Alger BE | Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses. | 2010 | Nat. Neurosci. | pmid:20348918 |
Hansen HS | Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain. | 2010 | Exp. Neurol. | pmid:20353771 |
Greco R et al. | The endocannabinoid system and migraine. | 2010 | Exp. Neurol. | pmid:20353780 |
Davies JW et al. | Pharmacology of capsaicin-, anandamide-, and N-arachidonoyl-dopamine-evoked cell death in a homogeneous transient receptor potential vanilloid subtype 1 receptor population. | 2010 | Br J Anaesth | pmid:20354008 |
Falenski KW et al. | FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration. | 2010 | Neuropsychopharmacology | pmid:20357755 |
Taylor AH et al. | Histomorphometric evaluation of cannabinoid receptor and anandamide modulating enzyme expression in the human endometrium through the menstrual cycle. | 2010 | Histochem. Cell Biol. | pmid:20369362 |
Wu WJ et al. | [Membrane cholesterol mediates the endocannabinoids-anandamide affection on HepG2 cells]. | 2010 | Zhonghua Gan Zang Bing Za Zhi | pmid:20380798 |
Hoot MR et al. | Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice. | 2010 | Brain Res. | pmid:20380816 |
Fisar Z | Inhibition of monoamine oxidase activity by cannabinoids. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20401651 |
Nallendran V et al. | The plasma levels of the endocannabinoid, anandamide, increase with the induction of labour. | 2010 | BJOG | pmid:20406230 |
Ying-Ying Y and Lin HC | Endocannabinoids and non-endocannabinoid fatty acid amides in cirrhosis. | 2010 | Liver Int. | pmid:20408944 |
Spradley JM et al. | Inhibitors of monoacylglycerol lipase, fatty-acid amide hydrolase and endocannabinoid transport differentially suppress capsaicin-induced behavioral sensitization through peripheral endocannabinoid mechanisms. | 2010 | Pharmacol. Res. | pmid:20416378 |
Placzek EA et al. | Lipidomic metabolism analysis of the endogenous cannabinoid anandamide (N-arachidonylethanolamide). | 2010 | J Pharm Biomed Anal | pmid:20417049 |
Ligresti A et al. | Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter. | 2010 | PLoS ONE | pmid:20422025 |
Annuzzi G et al. | Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients. | 2010 | Lipids Health Dis | pmid:20426869 |
Jumpertz R et al. | Circulating endocannabinoids and N-acyl-ethanolamides in patients with sleep apnea--specific role of oleoylethanolamide. | 2010 | Exp. Clin. Endocrinol. Diabetes | pmid:20429051 |
Burdyga G et al. | Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20430875 |
Hill MN et al. | Endogenous cannabinoid signaling is essential for stress adaptation. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20439721 |
Massa F et al. | Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. | 2010 | J. Neurosci. | pmid:20445053 |
Bari M et al. | Characterization of the endocannabinoid system in mouse embryonic stem cells. | 2011 | Stem Cells Dev. | pmid:20446814 |
Oddi S et al. | Pitfalls and solutions in assaying anandamide transport in cells. | 2010 | J. Lipid Res. | pmid:20447929 |