Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Derkinderen P et al. | Regulation of a neuronal form of focal adhesion kinase by anandamide. | 1996 | Science | pmid:8781236 |
Shimasue K et al. | Effects of anandamide and arachidonic acid on specific binding of (+) -PN200-110, diltiazem and (-) -desmethoxyverapamil to L-type Ca2+ channel. | 1996 | Eur. J. Pharmacol. | pmid:8904088 |
Sugiura T et al. | Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8573114 |
Shivachar AC et al. | Anandamide- and delta9-tetrahydrocannabinol-evoked arachidonic acid mobilization and blockade by SR141716A [N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4 -methyl-1H-pyrazole-3-carboximide hydrochloride]. | 1996 | Biochem. Pharmacol. | pmid:8615904 |
Stefano GB et al. | Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. | 1996 | J. Biol. Chem. | pmid:8702604 |
Di Marzo V et al. | Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. | 1996 | Biochem. J. | pmid:8670178 |
Yang ZM et al. | Activation of brain-type cannabinoid receptors interferes with preimplantation mouse embryo development. | 1996 | Biol. Reprod. | pmid:8879486 |
Varga K et al. | Mechanism of the hypotensive action of anandamide in anesthetized rats. | 1996 | Hypertension | pmid:8843898 |
Poling JS et al. | Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. | 1996 | Neuropharmacology | pmid:8938728 |
Di Marzo V et al. | Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8858137 |
Ishac EJ et al. | Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves. | 1996 | Br. J. Pharmacol. | pmid:8864538 |
Fride E and Mechoulam R | Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice. | 1996 | Brain Res. Dev. Brain Res. | pmid:8873985 |
Sugiura T et al. | 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma x glioma hybrid NG108-15 cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8954083 |
Stein EA et al. | Physiological and behavioural effects of the endogenous cannabinoid, arachidonylethanolamide (anandamide), in the rat. | 1996 | Br. J. Pharmacol. | pmid:8872363 |
Thomas BF et al. | Structure-activity analysis of anandamide analogs: relationship to a cannabinoid pharmacophore. | 1996 | J. Med. Chem. | pmid:8558515 |
Boring DL et al. | Cerebrodiene, arachidonyl-ethanolamide, and hybrid structures: potential for interaction with brain cannabinoid receptors. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8931121 |
Berdyshev EV et al. | Anandamide--a new look on fatty acid ethanolamides. | 1996 | J Lipid Mediat Cell Signal | pmid:9029374 |
Paria BC et al. | The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period. | 1996 | Mol. Reprod. Dev. | pmid:8914076 |
Sugiura T et al. | Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine. | 1996 | Eur. J. Biochem. | pmid:8797835 |
Langstein J et al. | cis-9,10-octadecenoamide, an endogenous sleep-inducing CNS compound, inhibits lymphocyte proliferation. | 1996 Jul-Aug | Res. Immunol. | pmid:8903105 |
Thomas EA et al. | Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system. | 1997 | J. Neurosci. Res. | pmid:9452020 |
Bisogno T et al. | The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9344854 |
Mechoulam R et al. | Anandamide may mediate sleep induction. | 1997 | Nature | pmid:9288961 |
Wiley JL et al. | Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. | 1997 | Pharmacol. Biochem. Behav. | pmid:9408225 |
Randall MD et al. | Comparative pharmacology of endothelium-derived hyperpolarizing factor and anandamide in rat isolated mesentery. | 1997 | Eur. J. Pharmacol. | pmid:9314035 |
Di Tomaso E et al. | Endogenous lipids that activate cannabinoid receptors. Formation and inactivation. | 1997 | Adv. Exp. Med. Biol. | pmid:9321973 |
White R and Hiley CR | A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. | 1997 | Br. J. Pharmacol. | pmid:9422801 |
Zygmunt PM et al. | Studies on the effects of anandamide in rat hepatic artery. | 1997 | Br. J. Pharmacol. | pmid:9422814 |
Jarrahian A and Hillard CJ | Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9431821 |
Schmid PC et al. | Anandamide and other N-acylethanolamines in mouse peritoneal macrophages. | 1997 | Chem. Phys. Lipids | pmid:9275307 |
Seltzman HH et al. | Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide. | 1997 | J. Med. Chem. | pmid:9357529 |
Cadogan AK et al. | Influence of cannabinoids on electrically evoked dopamine release and cyclic AMP generation in the rat striatum. | 1997 | J. Neurochem. | pmid:9282935 |
Deutsch DG et al. | Production and physiological actions of anandamide in the vasculature of the rat kidney. | 1997 | J. Clin. Invest. | pmid:9294122 |
Kurahashi Y et al. | Reversible hydrolysis and synthesis of anandamide demonstrated by recombinant rat fatty-acid amide hydrolase. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9299394 |
Wenger T et al. | Arachidonyl ethanolamide (anandamide) activates the parvocellular part of hypothalamic paraventricular nucleus. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9299434 |
Wenger T et al. | The effects of prenatally administered endogenous cannabinoid on rat offspring. | 1997 | Pharmacol. Biochem. Behav. | pmid:9300616 |
Hillard CJ et al. | Accumulation of N-arachidonoylethanolamine (anandamide) into cerebellar granule cells occurs via facilitated diffusion. | 1997 | J. Neurochem. | pmid:9231721 |
Lake KD et al. | Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9190833 |
Wenger T et al. | Effects of anandamide on gestation in pregnant rats. | 1997 | Life Sci. | pmid:9199480 |
Molina-Holgado F et al. | Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes. | 1997 | Neuroreport | pmid:9223079 |
Willoughby KA et al. | The biodisposition and metabolism of anandamide in mice. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9223560 |
Beltramo M et al. | Inhibition of anandamide hydrolysis in rat brain tissue by (E)-6-(bromomethylene) tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one. | 1997 | FEBS Lett. | pmid:9091314 |
Thumser AE et al. | A fluorescence displacement assay for the measurement of arachidonoyl ethanolamide (anandamide) and oleoyl amide (octadecenoamide) hydrolysis. | 1997 | Biochem. Pharmacol. | pmid:9065749 |
Ryan WJ et al. | Potent anandamide analogs: the effect of changing the length and branching of the end pentyl chain. | 1997 | J. Med. Chem. | pmid:9357528 |
Calignano A et al. | Inhibition of intestinal motility by anandamide, an endogenous cannabinoid. | 1997 | Eur. J. Pharmacol. | pmid:9537804 |
Soderstrom K et al. | Discovery of novel cannabinoid receptor ligands from diverse marine organisms. | 1997 | Adv. Exp. Med. Biol. | pmid:9561107 |
Fowler CJ et al. | Ibuprofen inhibits rat brain deamidation of anandamide at pharmacologically relevant concentrations. Mode of inhibition and structure-activity relationship. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9353392 |
Stark S et al. | Binding of aminoalkylindoles to noncannabinoid binding sites in NG108-15 cells. | 1997 | Cell. Mol. Neurobiol. | pmid:9353590 |
van der Stelt M et al. | The effect of hydroxylation of linoleoyl amides on their cannabinomimetic properties. | 1997 | FEBS Lett. | pmid:9357990 |
Beltramo M et al. | Functional role of high-affinity anandamide transport, as revealed by selective inhibition. | 1997 | Science | pmid:9262477 |