Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Ventricular Fibrillation D014693 16 associated lipids
Fever D005334 35 associated lipids
Bronchial Spasm D001986 18 associated lipids
Morphine Dependence D009021 9 associated lipids
Shock, Septic D012772 11 associated lipids
Cough D003371 19 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Catalepsy D002375 30 associated lipids
Migraine Disorders D008881 11 associated lipids
Cardiomyopathy, Dilated D002311 15 associated lipids
Alveolar Bone Loss D016301 10 associated lipids
Learning Disorders D007859 11 associated lipids
Hyperkinesis D006948 11 associated lipids
Hyperinsulinism D006946 27 associated lipids
Muscle Spasticity D009128 5 associated lipids
Hypothermia D007035 19 associated lipids
Celiac Disease D002446 16 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Hypertension, Portal D006975 12 associated lipids
Insulin Resistance D007333 99 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Brain Concussion D001924 5 associated lipids
Endotoxemia D019446 27 associated lipids
Anorexia D000855 8 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Memory Disorders D008569 33 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Overweight D050177 11 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Neuralgia D009437 28 associated lipids
Fibromyalgia D005356 4 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Mycoses D009181 18 associated lipids
Bulimia D002032 3 associated lipids
Sleep Deprivation D012892 5 associated lipids
Urinary Incontinence D014549 4 associated lipids
Vascular System Injuries D057772 2 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Pregnancy, Ectopic D011271 5 associated lipids
Ocular Hypotension D015814 2 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Impotence, Vasculogenic D018783 4 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Somatosensory Disorders D020886 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Wartmann M et al. The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide. 1995 FEBS Lett. pmid:7867785
Desarnaud F et al. Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization. 1995 J. Biol. Chem. pmid:7890734
Crawley JN et al. Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents. 1993 Pharmacol. Biochem. Behav. pmid:7906042
Van der Kloot W Anandamide, a naturally-occurring agonist of the cannabinoid receptor, blocks adenylate cyclase at the frog neuromuscular junction. 1994 Brain Res. pmid:7953630
Schwarz H et al. Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis. 1994 J. Neuroimmunol. pmid:7962480
Mechoulam R et al. Search for endogenous ligands of the cannabinoid receptor. 1994 Biochem. Pharmacol. pmid:7980618
Iversen L Pharmacology. Endogenous cannabinoids. 1994 Nature pmid:7990950
Di Marzo V et al. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. 1994 Nature pmid:7990962
Devane WA and Axelrod J Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8022836
Smith PB et al. The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice. 1994 J. Pharmacol. Exp. Ther. pmid:8035318
Schuel H et al. Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8052642
Koutek B et al. Inhibitors of arachidonoyl ethanolamide hydrolysis. 1994 J. Biol. Chem. pmid:8083191
Wickens AP and Pertwee RG delta 9-Tetrahydrocannabinol and anandamide enhance the ability of muscimol to induce catalepsy in the globus pallidus of rats. 1993 Eur. J. Pharmacol. pmid:8119321
Weidenfeld J et al. Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat. 1994 Neuroendocrinology pmid:8127398
Childers SR et al. Effects of anandamide on cannabinoid receptors in rat brain membranes. 1994 Biochem. Pharmacol. pmid:8129747
Devane WA New dawn of cannabinoid pharmacology. 1994 Trends Pharmacol. Sci. pmid:8165721
Kruszka KK and Gross RW The ATP- and CoA-independent synthesis of arachidonoylethanolamide. A novel mechanism underlying the synthesis of the endogenous ligand of the cannabinoid receptor. 1994 J. Biol. Chem. pmid:8182035
Bornheim LM et al. The effect of cannabidiol on mouse hepatic microsomal cytochrome P450-dependent anandamide metabolism. 1993 Biochem. Biophys. Res. Commun. pmid:8267610
Pertwee RG et al. Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2 and anandamide. 1993 Br. J. Pharmacol. pmid:8306090
Johnson DE et al. Isolation, identification and synthesis of an endogenous arachidonic amide that inhibits calcium channel antagonist 1,4-dihydropyridine binding. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8341720