Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Wartmann M et al. | The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide. | 1995 | FEBS Lett. | pmid:7867785 |
Desarnaud F et al. | Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization. | 1995 | J. Biol. Chem. | pmid:7890734 |
Crawley JN et al. | Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents. | 1993 | Pharmacol. Biochem. Behav. | pmid:7906042 |
Van der Kloot W | Anandamide, a naturally-occurring agonist of the cannabinoid receptor, blocks adenylate cyclase at the frog neuromuscular junction. | 1994 | Brain Res. | pmid:7953630 |
Schwarz H et al. | Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis. | 1994 | J. Neuroimmunol. | pmid:7962480 |
Mechoulam R et al. | Search for endogenous ligands of the cannabinoid receptor. | 1994 | Biochem. Pharmacol. | pmid:7980618 |
Iversen L | Pharmacology. Endogenous cannabinoids. | 1994 | Nature | pmid:7990950 |
Di Marzo V et al. | Formation and inactivation of endogenous cannabinoid anandamide in central neurons. | 1994 | Nature | pmid:7990962 |
Devane WA and Axelrod J | Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8022836 |
Smith PB et al. | The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8035318 |
Schuel H et al. | Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8052642 |
Koutek B et al. | Inhibitors of arachidonoyl ethanolamide hydrolysis. | 1994 | J. Biol. Chem. | pmid:8083191 |
Wickens AP and Pertwee RG | delta 9-Tetrahydrocannabinol and anandamide enhance the ability of muscimol to induce catalepsy in the globus pallidus of rats. | 1993 | Eur. J. Pharmacol. | pmid:8119321 |
Weidenfeld J et al. | Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat. | 1994 | Neuroendocrinology | pmid:8127398 |
Childers SR et al. | Effects of anandamide on cannabinoid receptors in rat brain membranes. | 1994 | Biochem. Pharmacol. | pmid:8129747 |
Devane WA | New dawn of cannabinoid pharmacology. | 1994 | Trends Pharmacol. Sci. | pmid:8165721 |
Kruszka KK and Gross RW | The ATP- and CoA-independent synthesis of arachidonoylethanolamide. A novel mechanism underlying the synthesis of the endogenous ligand of the cannabinoid receptor. | 1994 | J. Biol. Chem. | pmid:8182035 |
Bornheim LM et al. | The effect of cannabidiol on mouse hepatic microsomal cytochrome P450-dependent anandamide metabolism. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8267610 |
Pertwee RG et al. | Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2 and anandamide. | 1993 | Br. J. Pharmacol. | pmid:8306090 |
Johnson DE et al. | Isolation, identification and synthesis of an endogenous arachidonic amide that inhibits calcium channel antagonist 1,4-dihydropyridine binding. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8341720 |