| MeSH term | MeSH ID | Detail |
|---|---|---|
| Reperfusion Injury | D015427 | 65 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Ischemic Attack, Transient | D002546 | 42 associated lipids |
| Hyperalgesia | D006930 | 42 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Diabetic Retinopathy | D003930 | 39 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Myrdal SE and Steyger PS | TRPV1 regulators mediate gentamicin penetration of cultured kidney cells. | 2005 | Hear. Res. | pmid:15925202 |
| Pisani A et al. | High endogenous cannabinoid levels in the cerebrospinal fluid of untreated Parkinson's disease patients. | 2005 | Ann. Neurol. | pmid:15852389 |
| Venderova K et al. | Differential effects of endocannabinoids on [(3)H]-GABA uptake in the rat globus pallidus. | 2005 | Exp. Neurol. | pmid:15899265 |
| Monteleone P et al. | Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa. | 2005 | Neuropsychopharmacology | pmid:15841111 |
| Price TJ et al. | A role for the anandamide membrane transporter in TRPV1-mediated neurosecretion from trigeminal sensory neurons. | 2005 | Neuropharmacology | pmid:15992578 |
| Taddei S | Evolving the concept of regulation of vascular tone in humans. | 2005 | Br. J. Pharmacol. | pmid:15997231 |
| Hohmann AG et al. | An endocannabinoid mechanism for stress-induced analgesia. | 2005 | Nature | pmid:15973410 |
| Glaser ST et al. | Anandamide transport: a critical review. | 2005 | Life Sci. | pmid:15979096 |
| Ambrosi S et al. | On the importance of anandamide structural features for its interactions with DPPC bilayers: effects on PLA2 activity. | 2005 | J. Lipid Res. | pmid:15961786 |
| Tian X et al. | The conformation, location, and dynamic properties of the endocannabinoid ligand anandamide in a membrane bilayer. | 2005 | J. Biol. Chem. | pmid:15964843 |
| Ueda N et al. | N-acylphosphatidylethanolamine-hydrolyzing phospholipase D: a novel enzyme of the beta-lactamase fold family releasing anandamide and other N-acylethanolamines. | 2005 | Life Sci. | pmid:15949819 |
| Gamber KM et al. | Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus. | 2005 | Neuropharmacology | pmid:15949823 |
| Ueda N and Tsuboi K | [Enzymes involved in the biosynthesis and degradation of anandamide]. | 2005 | Seikagaku | pmid:16440755 |
| Elphick MR and Egertová M | The phylogenetic distribution and evolutionary origins of endocannabinoid signalling. | 2005 | Handb Exp Pharmacol | pmid:16596778 |
| Wiley JL et al. | Task specificity of cross-tolerance between Delta9-tetrahydrocannabinol and anandamide analogs in mice. | 2005 | Eur. J. Pharmacol. | pmid:15740725 |
| Tóth A et al. | Different vanilloid agonists cause different patterns of calcium response in CHO cells heterologously expressing rat TRPV1. | 2005 | Life Sci. | pmid:15820503 |
| Pacher P et al. | Hemodynamic profile, responsiveness to anandamide, and baroreflex sensitivity of mice lacking fatty acid amide hydrolase. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15821037 |
| Thomas A et al. | Evidence that the plant cannabinoid Delta9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist. | 2005 | Br. J. Pharmacol. | pmid:16205722 |
| Li C et al. | High affinity electrophilic and photoactivatable covalent endocannabinoid probes for the CB1 receptor. | 2005 | J. Med. Chem. | pmid:16190768 |
| Valenti M et al. | The endocannabinoid system in the brain of Carassius auratus and its possible role in the control of food intake. | 2005 | J. Neurochem. | pmid:16135090 |
| Matsuda K et al. | The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis. | 2005 | Tohoku J. Exp. Med. | pmid:16141678 |
| Rossato M et al. | Human sperm express cannabinoid receptor Cb1, the activation of which inhibits motility, acrosome reaction, and mitochondrial function. | 2005 | J. Clin. Endocrinol. Metab. | pmid:15562018 |
| Suplita RL et al. | Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal gray and rostral ventromedial medulla. | 2005 | Neuropharmacology | pmid:16129456 |
| Osei-Hyiaman D et al. | Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. | 2005 | Neuroendocrinology | pmid:16131814 |
| Mechoulam R and Deutsch DG | Toward an anandamide transporter. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16314567 |
| Ligresti A et al. | Endocannabinoid metabolic pathways and enzymes. | 2005 | Curr Drug Targets CNS Neurol Disord | pmid:16375679 |
| Flygare J et al. | Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma. | 2005 | FEBS Lett. | pmid:16337199 |
| Sarnataro D et al. | Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cells. | 2005 | FEBS Lett. | pmid:16263116 |
| Van Sickle MD et al. | Identification and functional characterization of brainstem cannabinoid CB2 receptors. | 2005 | Science | pmid:16224028 |
| Jiang W et al. | Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects. | 2005 | J. Clin. Invest. | pmid:16224541 |
| Cabranes A et al. | Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis. | 2005 | Neurobiol. Dis. | pmid:16242629 |
| Yamaguchi Y et al. | [Surgical stress]. | 2005 | Nihon Geka Gakkai Zasshi | pmid:16045189 |
| Wagner JA et al. | Coronary vasodilator effects of endogenous cannabinoids in vasopressin-preconstricted unpaced rat isolated hearts. | 2005 | J. Cardiovasc. Pharmacol. | pmid:16116341 |
| McPartland JM et al. | Cannabimimetic effects of osteopathic manipulative treatment. | 2005 | J Am Osteopath Assoc | pmid:16118355 |
| Schuel H and Burkman LJ | A tale of two cells: endocannabinoid-signaling regulates functions of neurons and sperm. | 2005 | Biol. Reprod. | pmid:16120829 |
| Besana A et al. | Lipids and two-pore domain K+ channels in excitable cells. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:16099395 |
| van der Stelt M and Di Marzo V | Anandamide as an intracellular messenger regulating ion channel activity. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:16099396 |
| Patsos HA et al. | The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2. | 2005 | Gut | pmid:16099783 |
| Yoshihara S et al. | Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways. | 2005 | Int. Arch. Allergy Immunol. | pmid:16103691 |
| van der Stelt M et al. | Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels. | 2005 | EMBO J. | pmid:16107881 |
| Lynch DL and Reggio PH | Molecular dynamics simulations of the endocannabinoid N-arachidonoylethanolamine (anandamide) in a phospholipid bilayer: probing structure and dynamics. | 2005 | J. Med. Chem. | pmid:16033262 |
| Wahn H et al. | The endocannabinoid arachidonyl ethanolamide (anandamide) increases pulmonary arterial pressure via cyclooxygenase-2 products in isolated rabbit lungs. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16055511 |
| Bari M et al. | Lipid rafts control signaling of type-1 cannabinoid receptors in neuronal cells. Implications for anandamide-induced apoptosis. | 2005 | J. Biol. Chem. | pmid:15657045 |
| Kurabayashi M et al. | 2-Arachidonoylglycerol increases in ischemia-reperfusion injury of the rat liver. | 2005 Jan-Feb | J Invest Surg | pmid:15804949 |
| Basavarajappa BS and Hungund BL | Role of the endocannabinoid system in the development of tolerance to alcohol. | 2005 Jan-Feb | Alcohol Alcohol. | pmid:15550443 |
| RodrÃguez de Fonseca F et al. | The endocannabinoid system: physiology and pharmacology. | 2005 Jan-Feb | Alcohol Alcohol. | pmid:15550444 |
| Abalo R et al. | Evaluation of the effect of age on cannabinoid receptor functionality and expression in guinea-pig ileum longitudinal muscle-myenteric plexus preparations. | 2005 Jul 22-29 | Neurosci. Lett. | pmid:15936532 |
| Glaser ST et al. | Endocannabinoids in the intact retina: 3 H-anandamide uptake, fatty acid amide hydrolase immunoreactivity and hydrolysis of anandamide. | 2005 Nov-Dec | Vis. Neurosci. | pmid:16469181 |
| Kukushkin ML et al. | Role of cannabinoid receptor agonists in mechanisms of suppression of central pain syndrome. | 2006 | Bull. Exp. Biol. Med. | pmid:17369898 |
| Szabo B et al. | Depolarization-induced retrograde synaptic inhibition in the mouse cerebellar cortex is mediated by 2-arachidonoylglycerol. | 2006 | J. Physiol. (Lond.) | pmid:16973696 |
| Wiley JL et al. | Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice. | 2006 | Life Sci. | pmid:16978656 |
| Thors L and Fowler CJ | Is there a temperature-dependent uptake of anandamide into cells? | 2006 | Br. J. Pharmacol. | pmid:16865094 |
| Guindon J and Beaulieu P | Antihyperalgesic effects of local injections of anandamide, ibuprofen, rofecoxib and their combinations in a model of neuropathic pain. | 2006 | Neuropharmacology | pmid:16442133 |
| Bermúdez-Siva FJ et al. | Activation of cannabinoid CB1 receptors induces glucose intolerance in rats. | 2006 | Eur. J. Pharmacol. | pmid:16423347 |
| Guagnini F et al. | Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P. | 2006 | Gut | pmid:16423891 |
| Meuth SG et al. | The contribution of TWIK-related acid-sensitive K+-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons. | 2006 | Mol. Pharmacol. | pmid:16424077 |
| Marx J | Drug development. Drugs inspired by a drug. | 2006 | Science | pmid:16424309 |
| Cupini LM et al. | Biochemical changes in endocannabinoid system are expressed in platelets of female but not male migraineurs. | 2006 | Cephalalgia | pmid:16472333 |
| GarcÃa Mdel C et al. | Role of CGRP and GABA in the hypotensive effect of intrathecally administered anandamide to anesthetized rats. | 2006 | Eur. J. Pharmacol. | pmid:16472800 |
| Romano MR and Lograno MD | Cannabinoid agonists induce relaxation in the bovine ophthalmic artery: evidences for CB1 receptors, nitric oxide and potassium channels. | 2006 | Br. J. Pharmacol. | pmid:16474412 |
| Tuccinardi T et al. | Cannabinoid CB2/CB1 selectivity. Receptor modeling and automated docking analysis. | 2006 | J. Med. Chem. | pmid:16451064 |
| Monterrubio S and Solowij N | Chronic stress and adaptation. | 2006 | Am J Psychiatry | pmid:16513893 |
| Bari M et al. | New insights into endocannabinoid degradation and its therapeutic potential. | 2006 | Mini Rev Med Chem | pmid:16515464 |
| Overton HA et al. | Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. | 2006 | Cell Metab. | pmid:16517404 |
| Matias I et al. | Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17011761 |
| Fowler CJ | The cannabinoid system and its pharmacological manipulation--a review, with emphasis upon the uptake and hydrolysis of anandamide. | 2006 | Fundam Clin Pharmacol | pmid:17109648 |
| De Lago E et al. | Acyl-based anandamide uptake inhibitors cause rapid toxicity to C6 glioma cells at pharmacologically relevant concentrations. | 2006 | J. Neurochem. | pmid:16899063 |
| Laezza C et al. | Anandamide inhibits Cdk2 and activates Chk1 leading to cell cycle arrest in human breast cancer cells. | 2006 | FEBS Lett. | pmid:17055492 |
| Gough NR | Focus issue: signaling lipids. | 2006 | Sci. STKE | pmid:16467192 |
| Migliarini B et al. | Endocannabinoid system in Xenopus laevis development: CB1 receptor dynamics. | 2006 | FEBS Lett. | pmid:16519888 |
| Wang J et al. | Functional analysis of the purified anandamide-generating phospholipase D as a member of the metallo-beta-lactamase family. | 2006 | J. Biol. Chem. | pmid:16527816 |
| Bortolato M et al. | Anxiolytic-like properties of the anandamide transport inhibitor AM404. | 2006 | Neuropsychopharmacology | pmid:16541083 |
| Maccarrone M et al. | Regulation by cannabinoid receptors of anandamide transport across the blood-brain barrier and through other endothelial cells. | 2006 | Thromb. Haemost. | pmid:16543970 |
| Siegmund SV et al. | Fatty acid amide hydrolase determines anandamide-induced cell death in the liver. | 2006 | J. Biol. Chem. | pmid:16418162 |
| Salo OM et al. | 3D-QSAR studies on cannabinoid CB1 receptor agonists: G-protein activation as biological data. | 2006 | J. Med. Chem. | pmid:16420041 |
| Varvel SA et al. | Fatty acid amide hydrolase (-/-) mice exhibit an increased sensitivity to the disruptive effects of anandamide or oleamide in a working memory water maze task. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16352706 |
| Wei BQ et al. | A second fatty acid amide hydrolase with variable distribution among placental mammals. | 2006 | J. Biol. Chem. | pmid:17015445 |
| Balas L et al. | Synthesis of a potential photoactivatable anandamide analog. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16682198 |
| Shouman B et al. | Endocannabinoids potently protect the newborn brain against AMPA-kainate receptor-mediated excitotoxic damage. | 2006 | Br. J. Pharmacol. | pmid:16682966 |
| Zaniewska M et al. | Evaluation of the role of nicotinic acetylcholine receptor subtypes and cannabinoid system in the discriminative stimulus effects of nicotine in rats. | 2006 | Eur. J. Pharmacol. | pmid:16730696 |
| Harada N et al. | Antithrombin reduces endotoxin-induced hypotension by enhancing pulmonary sensory neuron activation in rats. | 2006 | Thromb. Haemost. | pmid:16732381 |
| van der Stelt M et al. | Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels. | 2006 | Cell. Mol. Life Sci. | pmid:16732431 |
| Fisyunov A et al. | Cannabinoids modulate the P-type high-voltage-activated calcium currents in purkinje neurons. | 2006 | J. Neurophysiol. | pmid:16738209 |
| Vogeser M et al. | Release of anandamide from blood cells. | 2006 | Clin. Chem. Lab. Med. | pmid:16599845 |
| Kopczyńska B and Szereda-Przestaszewska M | Supranodose vagotomy eliminates anandamide-evoked cardiorespiratory depression in anaesthetized rats. | 2006 | Respir Physiol Neurobiol | pmid:16144778 |
| Wang H et al. | Fatty acid amide hydrolase deficiency limits early pregnancy events. | 2006 | J. Clin. Invest. | pmid:16886060 |
| Wiles AL et al. | N-Arachidonyl-glycine inhibits the glycine transporter, GLYT2a. | 2006 | J. Neurochem. | pmid:16899062 |
| Dembiński A et al. | Cannabinoids in acute gastric damage and pancreatitis. | 2006 | J. Physiol. Pharmacol. | pmid:17218765 |
| Nakajima Y et al. | Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition. | 2006 | FEBS Lett. | pmid:16406050 |
| Juan-Picó P et al. | Cannabinoid receptors regulate Ca(2+) signals and insulin secretion in pancreatic beta-cell. | 2006 | Cell Calcium | pmid:16321437 |
| Cannizzaro C et al. | Presynaptic effects of anandamide and WIN55,212-2 on glutamatergic nerve endings isolated from rat hippocampus. | 2006 | Neurochem. Int. | pmid:16325966 |
| Lizanecz E et al. | Phosphorylation-dependent desensitization by anandamide of vanilloid receptor-1 (TRPV1) function in rat skeletal muscle arterioles and in Chinese hamster ovary cells expressing TRPV1. | 2006 | Mol. Pharmacol. | pmid:16338989 |
| Moezi L et al. | Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB(1) and VR(1) receptors. | 2006 | Br. J. Pharmacol. | pmid:17043671 |
| Grimaldi C et al. | Anandamide inhibits adhesion and migration of breast cancer cells. | 2006 | Exp. Cell Res. | pmid:16343481 |
| Eljaschewitsch E et al. | The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. | 2006 | Neuron | pmid:16387640 |
| de Lago E et al. | UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders. | 2006 | Eur Neuropsychopharmacol | pmid:16006105 |
| Yang YY et al. | Roles of anandamide in the hepatic microcirculation in cirrhotic rats. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16407591 |
| Glaser ST et al. | Ex vivo imaging of fatty acid amide hydrolase activity and its inhibition in the mouse brain. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16278311 |
| Appendino G et al. | First "hybrid" ligands of vanilloid TRPV1 and cannabinoid CB2 receptors and non-polyunsaturated fatty acid-derived CB2-selective ligands. | 2006 | FEBS Lett. | pmid:16406364 |
| Malfitano AM et al. | Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis. | 2006 | J. Neuroimmunol. | pmid:16239036 |