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Behavioral pharmacology of cannabinoids with a focus on preclinical models for studying reinforcing and dependence-producing properties. |
2008 |
Curr Drug Abuse Rev |
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The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6. |
2008 |
J. Pharmacol. Exp. Ther. |
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Anandamide inhibition of 5-HT3A receptors varies with receptor density and desensitization. |
2008 |
Mol. Pharmacol. |
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Prolonged glucocorticoid treatment decreases cannabinoid CB1 receptor density in the hippocampus. |
2008 |
Hippocampus |
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Localization of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) expression in mouse brain: A new perspective on N-acylethanolamines as neural signaling molecules. |
2008 |
J. Comp. Neurol. |
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Endocannabinoid modulation of male rat sexual behavior. |
2008 |
Psychopharmacology (Berl.) |
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A potential function of endocannabinoids in the selection of a navigation strategy by rats. |
2008 |
Psychopharmacology (Berl.) |
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Peripheral endocannabinoid system activity in patients treated with sibutramine. |
2008 |
Obesity (Silver Spring) |
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Effects of cocaine in 5-lipoxygenase-deficient mice. |
2008 |
J Neural Transm |
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Evaluation of fatty acid amides in the carrageenan-induced paw edema model. |
2008 |
Neuropharmacology |
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The endocannabinoid system in brain reward processes. |
2008 |
Br. J. Pharmacol. |
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Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. |
2008 |
Arthritis Res. Ther. |
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Biosynthesis, degradation and pharmacological importance of the fatty acid amides. |
2008 |
Drug Discov. Today |
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Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents. |
2008 |
Neuroimage |
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Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine. |
2008 |
Biochem. Pharmacol. |
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Expression and secretion of N-acylethanolamine-hydrolysing acid amidase in human prostate cancer cells. |
2008 |
J. Biochem. |
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The anandamide membrane transporter inhibitor, VDM-11, modulates sleep and c-Fos expression in the rat brain. |
2008 |
Neuroscience |
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Direct activation of transient receptor potential vanilloid 1(TRPV1) by diacylglycerol (DAG). |
2008 |
Mol Pain |
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The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway. |
2008 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Bambico FR and Gobbi G |
The cannabinoid CB1 receptor and the endocannabinoid anandamide: possible antidepressant targets. |
2008 |
Expert Opin. Ther. Targets |
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Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. |
2008 |
Eur Neuropsychopharmacol |
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Does the hydrolysis of 2-arachidonoylglycerol regulate its cellular uptake? |
2008 |
Pharmacol. Res. |
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Systematic evaluation of nitric oxide, tetrahydrobiopterin, and anandamide levels in a porcine model of endotoxemia. |
2008 |
J Anesth |
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Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test. |
2008 |
Eur. J. Pharmacol. |
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IP(3)R-mediated Ca(2+) release is modulated by anandamide in isolated cardiac nuclei. |
2008 |
J. Mol. Cell. Cardiol. |
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High levels of anandamide, an endogenous cannabinoid, block the growth of sheep preimplantation embryos by inducing apoptosis and reversible arrest of cell proliferation. |
2008 |
Hum. Reprod. |
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Anandamide as a marker of human disease. |
2008 |
JAMA |
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Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment. |
2008 |
J. Neurochem. |
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[Effect of ethanol on anandamide-induced sensory nerve dependent vasorelaxation (the second report)]. |
2008 |
Nihon Arukoru Yakubutsu Igakkai Zasshi |
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Acutely reduced locomotor activity is a major contributor to Western diet-induced obesity in mice. |
2008 |
Am. J. Physiol. Endocrinol. Metab. |
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The group IV afferent neuron expresses multiple receptor alterations in cardiomyopathyic rats: evidence at the cannabinoid CB1 receptor. |
2008 |
J. Physiol. (Lond.) |
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Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates. |
2008 |
Biol. Psychiatry |
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An optimized GC-MS method detects nanomolar amounts of anandamide in mouse brain. |
2008 |
Anal. Biochem. |
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The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization. |
2008 |
Behav. Brain Res. |
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Anandamide inhibits IL-12p40 production by acting on the promoter repressor element GA-12: possible involvement of the COX-2 metabolite prostamide E(2). |
2008 |
Biochem. J. |
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Effectiveness of continuous hemodiafiltration using a polymethylmethacrylate membrane hemofilter after polymyxin B-immobilized fiber column therapy of septic shock. |
2008 Jan-Feb |
ASAIO J. |
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The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. |
2008 Nov-Dec |
Anticancer Res. |
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Differential stimulatory effects of cannabinoids on VIP release and NO synthase activity in synaptosomal fractions from rat ileum. |
2008 Oct-Dec |
Neuropeptides |
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N-acyldopamines control striatal input terminals via novel ligand-gated cation channels. |
2009 |
Neuropharmacology |
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Simultaneous quantitative analysis of N-acylethanolamides in clinical samples. |
2009 |
Anal. Biochem. |
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Role of anandamide transporter in regulating calcitonin gene-related peptide production and blood pressure in hypertension. |
2009 |
J. Hypertens. |
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Cannabinoid 1 receptor activation inhibits transient receptor potential vanilloid type 1 receptor-mediated cationic influx into rat cultured primary sensory neurons. |
2009 |
Neuroscience |
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Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. |
2009 |
Eur. J. Pharmacol. |
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Anandamide regulates lipopolysaccharide-induced nitric oxide synthesis and tissue damage in the murine uterus. |
2009 |
Reprod. Biomed. Online |
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A new role of anandamide in human sperm: focus on metabolism. |
2009 |
J. Cell. Physiol. |
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Kingsley PJ and Marnett LJ |
Analysis of endocannabinoids, their congeners and COX-2 metabolites. |
2009 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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Dowie MJ et al. |
Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. |
2009 |
Neuroscience |
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Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task. |
2009 |
Neurobiol Learn Mem |
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Increased serum anandamide level at ruptured plaque site in patients with acute myocardial infarction. |
2009 |
Fundam Clin Pharmacol |
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Straiker A and Mackie K |
Cannabinoid signaling in inhibitory autaptic hippocampal neurons. |
2009 |
Neuroscience |
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Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. |
2009 |
J. Pharmacol. Exp. Ther. |
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Brighton PJ et al. |
Characterization of anandamide-stimulated cannabinoid receptor signaling in human ULTR myometrial smooth muscle cells. |
2009 |
Mol. Endocrinol. |
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Organized trafficking of anandamide and related lipids. |
2009 |
Vitam. Horm. |
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Anandamide receptor signal transduction. |
2009 |
Vitam. Horm. |
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Is GPR55 an anandamide receptor? |
2009 |
Vitam. Horm. |
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The endocannabinoid anandamide from immunomodulation to neuroprotection. Implications for multiple sclerosis. |
2009 |
Vitam. Horm. |
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Anandamide and the vanilloid receptor (TRPV1). |
2009 |
Vitam. Horm. |
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Regulation of gene transcription and keratinocyte differentiation by anandamide. |
2009 |
Vitam. Horm. |
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Changes in the endocannabinoid system may give insight into new and effective treatments for cancer. |
2009 |
Vitam. Horm. |
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Targeted lipidomics as a tool to investigate endocannabinoid function. |
2009 |
Int. Rev. Neurobiol. |
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Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. |
2009 |
Endocrinology |
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Altered anandamide degradation in attention-deficit/hyperactivity disorder. |
2009 |
Neurology |
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Endocannabinoids anandamide and its cannabinoid receptors in liver fibrosis after murine schistosomiasis. |
2009 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
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Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-alpha nuclear receptors. |
2009 |
Learn. Mem. |
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A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells. |
2009 |
J. Neurosci. |
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Total synthesis of photoactivatable or fluorescent anandamide probes: novel bioactive compounds with angiogenic activity. |
2009 |
J. Med. Chem. |
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Factors influencing the regional haemodynamic responses to methanandamide and anandamide in conscious rats. |
2009 |
Br. J. Pharmacol. |
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The endocannabinoid system and pain. |
2009 |
CNS Neurol Disord Drug Targets |
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Anandamide increases the differentiation of rat adipocytes and causes PPARgamma and CB1 receptor upregulation. |
2009 |
Obesity (Silver Spring) |
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Marco EM and Viveros MP |
The critical role of the endocannabinoid system in emotional homeostasis: avoiding excess and deficiencies. |
2009 |
Mini Rev Med Chem |
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Endocannabinoid system and nitric oxide are involved in the deleterious effects of lipopolysaccharide on murine decidua. |
2009 |
Placenta |
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Electrophysiological effects of anandamide on rat myocardium. |
2009 |
Br. J. Pharmacol. |
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Hiley CR |
Endocannabinoids and the heart. |
2009 |
J. Cardiovasc. Pharmacol. |
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Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. |
2009 |
J. Urol. |
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Localisation and function of the endocannabinoid system in the human ovary. |
2009 |
PLoS ONE |
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Parker LA et al. |
The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew). |
2009 |
Physiol. Behav. |
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Schlosburg JE et al. |
Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation. |
2009 |
AAPS J |
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Tang B et al. |
Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells. |
2009 |
Am. J. Respir. Cell Mol. Biol. |
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In vitro synthesis of arachidonoyl amino acids by cytochrome c. |
2009 |
Prostaglandins Other Lipid Mediat. |
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Cottone E et al. |
Goldfish CB1 mRNA expression is affected by fasting and anandamide administration. |
2009 |
Neuroreport |
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Central cannabinoid 1 receptor antagonist administration prevents endotoxic hypotension affecting norepinephrine release in the preoptic anterior hypothalamic area. |
2009 |
Shock |
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Izzo AA et al. |
Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. |
2009 |
Br. J. Pharmacol. |
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Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes. |
2009 |
J. Med. Chem. |
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El-Talatini MR et al. |
Fluctuation in anandamide levels from ovulation to early pregnancy in in-vitro fertilization-embryo transfer women, and its hormonal regulation. |
2009 |
Hum. Reprod. |
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Brizzi A et al. |
New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. |
2009 |
J. Med. Chem. |
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Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. |
2009 |
Br J Psychiatry |
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Mangieri RA et al. |
An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. |
2009 |
Psychopharmacology (Berl.) |
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Potenzieri C et al. |
Excitation of cutaneous C nociceptors by intraplantar administration of anandamide. |
2009 |
Brain Res. |
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De Petrocellis L and Di Marzo V |
An introduction to the endocannabinoid system: from the early to the latest concepts. |
2009 |
Best Pract. Res. Clin. Endocrinol. Metab. |
pmid:19285257
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Borrelli F and Izzo AA |
Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance. |
2009 |
Best Pract. Res. Clin. Endocrinol. Metab. |
pmid:19285259
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Bermúdez-Silva FJ et al. |
The role of the pancreatic endocannabinoid system in glucose metabolism. |
2009 |
Best Pract. Res. Clin. Endocrinol. Metab. |
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Rossi F et al. |
The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption. |
2009 |
Bone |
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Jiang LS et al. |
Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages. |
2009 |
Cardiovasc. Res. |
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Aneetha H et al. |
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals. |
2009 |
Bioorg. Med. Chem. Lett. |
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Panlilio LV et al. |
Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats. |
2009 |
Psychopharmacology (Berl.) |
pmid:19015836
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De Petrocellis L et al. |
Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide. |
2009 |
J. Lipid Res. |
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Tuboly G et al. |
Antinociceptive interactions between anandamide and endomorphin-1 at the spinal level. |
2009 |
Clin. Exp. Pharmacol. Physiol. |
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Schacht JP et al. |
Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. |
2009 |
Psychopharmacology (Berl.) |
pmid:19002671
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Araújo JR et al. |
Effect of cannabinoids upon the uptake of folic acid by BeWo cells. |
2009 |
Pharmacology |
pmid:19145103
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Van Dross RT |
Metabolism of anandamide by COX-2 is necessary for endocannabinoid-induced cell death in tumorigenic keratinocytes. |
2009 |
Mol. Carcinog. |
pmid:19148897
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