Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Cholangiocarcinoma D018281 7 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Alveolar Bone Loss D016301 10 associated lipids
Ocular Hypotension D015814 2 associated lipids
Weight Gain D015430 101 associated lipids
Reperfusion Injury D015427 65 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Urinary Incontinence D014549 4 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
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Gurney AM et al. Two-pore domain K channel, TASK-1, in pulmonary artery smooth muscle cells. 2003 Circ. Res. pmid:14551239
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Maccarrone M et al. Progesterone activates fatty acid amide hydrolase (FAAH) promoter in human T lymphocytes through the transcription factor Ikaros. Evidence for a synergistic effect of leptin. 2003 J. Biol. Chem. pmid:12799380
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Cravatt BF and Lichtman AH Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system. 2003 Curr Opin Chem Biol pmid:12941421
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Mimeault M et al. Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. 2003 Prostate pmid:12746841
López-Rodríguez ML et al. Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors. 2003 Eur J Med Chem pmid:12750028
Derkinderen P et al. Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus. 2003 J. Neurosci. pmid:12657697
Jonsson KO et al. AM404 and VDM 11 non-specifically inhibit C6 glioma cell proliferation at concentrations used to block the cellular accumulation of the endocannabinoid anandamide. 2003 Arch. Toxicol. pmid:12698235
López-Rodríguez ML et al. Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase. 2003 J. Med. Chem. pmid:12672252
Murillo-Rodriguez E et al. Anandamide enhances extracellular levels of adenosine and induces sleep: an in vivo microdialysis study. 2003 Sleep pmid:14746372
Scorticati C et al. The effect of anandamide on prolactin secretion is modulated by estrogen. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:12578974
Ahluwalia J et al. Activation of capsaicin-sensitive primary sensory neurones induces anandamide production and release. 2003 J. Neurochem. pmid:12558978
Sancho R et al. Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway. 2003 Mol. Pharmacol. pmid:12527815
Jennings EA et al. The actions of anandamide on rat superficial medullary dorsal horn neurons in vitro. 2003 J. Physiol. (Lond.) pmid:12562891
Randall MD A new endothelial target for cannabinoids. 2003 Mol. Pharmacol. pmid:12606752
Wisnoskey BJ et al. Activation of vanilloid receptor type I in the endoplasmic reticulum fails to activate store-operated Ca2+ entry. 2003 Biochem. J. pmid:12608892
Vandevoorde S et al. N-Morpholino- and N-diethyl-analogues of palmitoylethanolamide increase the sensitivity of transfected human vanilloid receptors to activation by anandamide without affecting fatty acid amidohydrolase activity. 2003 Bioorg. Med. Chem. pmid:12614867
Lau AH and Chow SS Effects of cannabinoid receptor agonists on immunologically induced histamine release from rat peritoneal mast cells. 2003 Eur. J. Pharmacol. pmid:12620517
Maccarrone M et al. Anandamide activity and degradation are regulated by early postnatal aging and follicle-stimulating hormone in mouse Sertoli cells. 2003 Endocrinology pmid:12488326
Orliac ML et al. Potentiation of anandamide effects in mesenteric beds isolated from endotoxemic rats. 2003 J. Pharmacol. Exp. Ther. pmid:12490589
Schelegle ES Functional morphology and physiology of slowly adapting pulmonary stretch receptors. 2003 Anat Rec A Discov Mol Cell Evol Biol pmid:12494485
Lee LY et al. Functional morphology and physiological properties of bronchopulmonary C-fiber afferents. 2003 Anat Rec A Discov Mol Cell Evol Biol pmid:12494486
Higgs S et al. Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716. 2003 Psychopharmacology (Berl.) pmid:12447606
Facchinetti F et al. Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide. 2003 Glia pmid:12509806
Kathuria S et al. Modulation of anxiety through blockade of anandamide hydrolysis. 2003 Nat. Med. pmid:12461523
Németh J et al. Concentration-dependent dual effect of anandamide on sensory neuropeptide release from isolated rat tracheae. 2003 Neurosci. Lett. pmid:12499047
Patel S et al. The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase. 2003 Br. J. Pharmacol. pmid:12839875
Watanabe H et al. Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. 2003 Nature pmid:12879072
Kozak KR et al. Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid anandamide. 2003 Biochemistry pmid:12885237
Wenger T et al. The endogenous cannabinoid, anandamide, activates the hypothalamo-pituitary-adrenal axis in CB1 cannabinoid receptor knockout mice. 2003 Neuroendocrinology pmid:14688442
Costanzi M et al. Anandamide and memory in CD1 mice: effects of immobilization stress and of prior experience. 2003 Neurobiol Learn Mem pmid:12676519
Fowler CJ et al. Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin. 2003 J Enzyme Inhib Med Chem pmid:14506913