Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Cardiomyopathy, Dilated D002311 15 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Celiac Disease D002446 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Bronchial Spasm D001986 18 associated lipids
Mycoses D009181 18 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Peptic Ulcer D010437 19 associated lipids
Cough D003371 19 associated lipids
Hypothermia D007035 19 associated lipids
Ataxia D001259 20 associated lipids
Brain Edema D001929 20 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Breast Neoplasms D001943 24 associated lipids
Hyperemia D006940 25 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Weidenfeld J et al. Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat. 1994 Neuroendocrinology pmid:8127398
Childers SR et al. Effects of anandamide on cannabinoid receptors in rat brain membranes. 1994 Biochem. Pharmacol. pmid:8129747
Devane WA New dawn of cannabinoid pharmacology. 1994 Trends Pharmacol. Sci. pmid:8165721
Iversen L Pharmacology. Endogenous cannabinoids. 1994 Nature pmid:7990950
Schwarz H et al. Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis. 1994 J. Neuroimmunol. pmid:7962480
Di Marzo V et al. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. 1994 Nature pmid:7990962
Schuel H et al. Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8052642
Smith PB et al. The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice. 1994 J. Pharmacol. Exp. Ther. pmid:8035318
Mechoulam R et al. Search for endogenous ligands of the cannabinoid receptor. 1994 Biochem. Pharmacol. pmid:7980618
Koutek B et al. Inhibitors of arachidonoyl ethanolamide hydrolysis. 1994 J. Biol. Chem. pmid:8083191
Kruszka KK and Gross RW The ATP- and CoA-independent synthesis of arachidonoylethanolamide. A novel mechanism underlying the synthesis of the endogenous ligand of the cannabinoid receptor. 1994 J. Biol. Chem. pmid:8182035
Devane WA and Axelrod J Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8022836
Hillard CJ et al. Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain. 1995 Biochim. Biophys. Acta pmid:7647100
Fride E et al. Low doses of anandamides inhibit pharmacological effects of delta 9-tetrahydrocannabinol. 1995 J. Pharmacol. Exp. Ther. pmid:7853184
Facci L et al. Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7724569
Hampson AJ et al. Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor. 1995 Biochim. Biophys. Acta pmid:7488638
Mechoulam R et al. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. 1995 Biochem. Pharmacol. pmid:7605349
Felder CC et al. Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. 1995 Mol. Pharmacol. pmid:7565624
Vela G et al. Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine. 1995 Neuropharmacology pmid:7566503
Hansen HS et al. Glutamate stimulates the formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cortical neurons in culture. 1995 Biochim. Biophys. Acta pmid:7548201