Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Catalepsy D002375 30 associated lipids
Obesity D009765 29 associated lipids
Neuralgia D009437 28 associated lipids
Hyperinsulinism D006946 27 associated lipids
Endotoxemia D019446 27 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Hyperemia D006940 25 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Breast Neoplasms D001943 24 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Ataxia D001259 20 associated lipids
Brain Edema D001929 20 associated lipids
Cough D003371 19 associated lipids
Hypothermia D007035 19 associated lipids
Peptic Ulcer D010437 19 associated lipids
Mycoses D009181 18 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Bronchial Spasm D001986 18 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Wiley JL et al. Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. 1997 Pharmacol. Biochem. Behav. pmid:9408225
Randall MD et al. Comparative pharmacology of endothelium-derived hyperpolarizing factor and anandamide in rat isolated mesentery. 1997 Eur. J. Pharmacol. pmid:9314035
Di Tomaso E et al. Endogenous lipids that activate cannabinoid receptors. Formation and inactivation. 1997 Adv. Exp. Med. Biol. pmid:9321973
White R and Hiley CR A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. 1997 Br. J. Pharmacol. pmid:9422801
Zygmunt PM et al. Studies on the effects of anandamide in rat hepatic artery. 1997 Br. J. Pharmacol. pmid:9422814
Jarrahian A and Hillard CJ Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9431821
Sasaki T and Chang MC N-arachidonylethanolamine (anandamide) formation from N-arachidonylphosphatidylethanolamine in rat brain membranes. 1997 Life Sci. pmid:9365227
Randall MD and Kendall DA Involvement of a cannabinoid in endothelium-derived hyperpolarizing factor-mediated coronary vasorelaxation. 1997 Eur. J. Pharmacol. pmid:9369375
Burkey TH et al. Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain. 1997 Eur. J. Pharmacol. pmid:9384246
Calignano A et al. Potentiation of anandamide hypotension by the transport inhibitor, AM404. 1997 Eur. J. Pharmacol. pmid:9389389
Wenger T et al. Arachidonyl ethanolamide (anandamide) activates the parvocellular part of hypothalamic paraventricular nucleus. 1997 Biochem. Biophys. Res. Commun. pmid:9299434
Wenger T et al. The effects of prenatally administered endogenous cannabinoid on rat offspring. 1997 Pharmacol. Biochem. Behav. pmid:9300616
Hillard CJ et al. Accumulation of N-arachidonoylethanolamine (anandamide) into cerebellar granule cells occurs via facilitated diffusion. 1997 J. Neurochem. pmid:9231721
Lake KD et al. Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors. 1997 J. Pharmacol. Exp. Ther. pmid:9190833
Wenger T et al. Effects of anandamide on gestation in pregnant rats. 1997 Life Sci. pmid:9199480
Molina-Holgado F et al. Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes. 1997 Neuroreport pmid:9223079
Willoughby KA et al. The biodisposition and metabolism of anandamide in mice. 1997 J. Pharmacol. Exp. Ther. pmid:9223560
Beltramo M et al. Inhibition of anandamide hydrolysis in rat brain tissue by (E)-6-(bromomethylene) tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one. 1997 FEBS Lett. pmid:9091314
Thumser AE et al. A fluorescence displacement assay for the measurement of arachidonoyl ethanolamide (anandamide) and oleoyl amide (octadecenoamide) hydrolysis. 1997 Biochem. Pharmacol. pmid:9065749
Bisogno T et al. Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. 1997 Biochem. J. pmid:9065792
De Petrocellis L et al. Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase. 1997 Biochem. Biophys. Res. Commun. pmid:9070224
Deutsch DG et al. Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor. 1997 Biochem. Biophys. Res. Commun. pmid:9070252
Lake KD et al. Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. 1997 Hypertension pmid:9149688
Bisogno T et al. Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus. 1997 Biochim. Biophys. Acta pmid:9150253
Stefano GB et al. Identification and characterization of the leech CNS cannabinoid receptor: coupling to nitric oxide release. 1997 Brain Res. pmid:9125406
Mechoulam R Todd's achievement. 1997 Nature pmid:9126725
Koga D et al. Liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric determination of anandamide and its analogs in rat brain and peripheral tissues. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9106024
Schmid PC et al. Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9108127
Calignano A et al. Inhibition of intestinal motility by anandamide, an endogenous cannabinoid. 1997 Eur. J. Pharmacol. pmid:9537804
Soderstrom K et al. Discovery of novel cannabinoid receptor ligands from diverse marine organisms. 1997 Adv. Exp. Med. Biol. pmid:9561107
Fowler CJ et al. Ibuprofen inhibits rat brain deamidation of anandamide at pharmacologically relevant concentrations. Mode of inhibition and structure-activity relationship. 1997 J. Pharmacol. Exp. Ther. pmid:9353392
Stark S et al. Binding of aminoalkylindoles to noncannabinoid binding sites in NG108-15 cells. 1997 Cell. Mol. Neurobiol. pmid:9353590
van der Stelt M et al. The effect of hydroxylation of linoleoyl amides on their cannabinomimetic properties. 1997 FEBS Lett. pmid:9357990
Beltramo M et al. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. 1997 Science pmid:9262477
Valk P et al. Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells. 1997 Blood pmid:9269762
Twitchell W et al. Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons. 1997 J. Neurophysiol. pmid:9242259
Matsuda S et al. Metabolism of anandamide, an endogenous cannabinoid receptor ligand, in porcine ocular tissues. 1997 Exp. Eye Res. pmid:9245900
Wagner JA et al. Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. 1997 Nature pmid:9394002
Compton DR and Martin BR The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity. 1997 J. Pharmacol. Exp. Ther. pmid:9399986
Stella N et al. A second endogenous cannabinoid that modulates long-term potentiation. 1997 Nature pmid:9285589
Mikawa Y et al. Ocular activity of topically administered anandamide in the rabbit. 1997 Jul-Aug Jpn. J. Ophthalmol. pmid:9304433
Stefano GB et al. Antagonism of LPS and IFN-gamma induction of iNOS in human saphenous vein endothelium by morphine and anandamide by nitric oxide inhibition of adenylate cyclase. 1998 J. Cardiovasc. Pharmacol. pmid:9641464
Stefano GB et al. Long-term exposure of human blood vessels to HIV gp120, morphine, and anandamide increases endothelial adhesion of monocytes: uncoupling of nitric oxide release. 1998 J. Cardiovasc. Pharmacol. pmid:9641470
Ueda N et al. A hydrolase enzyme inactivating endogenous ligands for cannabinoid receptors. 1998 J. Med. Invest. pmid:9864962
Mechoulam R et al. Endocannabinoids. 1998 Eur. J. Pharmacol. pmid:9831287
Derocq JM et al. The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor-independent pathway in hematopoietic cell lines. 1998 FEBS Lett. pmid:9563506
Edgemond WS et al. Human platelets and polymorphonuclear leukocytes synthesize oxygenated derivatives of arachidonylethanolamide (anandamide): their affinities for cannabinoid receptors and pathways of inactivation. 1998 Mol. Pharmacol. pmid:9658204
Tong W et al. Derivation of a pharmacophore model for anandamide using constrained conformational searching and comparative molecular field analysis. 1998 J. Med. Chem. pmid:9784095
Richardson JD et al. Antihyperalgesic effects of spinal cannabinoids. 1998 Eur. J. Pharmacol. pmid:9600630
Richardson JD et al. Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. 1998 Pain pmid:9539680