Oka S et al. |
Depolarization-induced rapid generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in rat brain synaptosomes. |
2007 |
J. Biochem. |
pmid:17339228
|
D'Argenio G et al. |
Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. |
2007 |
J. Mol. Med. |
pmid:17396241
|
Holt S et al. |
Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin. |
2007 |
Eur. J. Pharmacol. |
pmid:17397826
|
Mahler SV et al. |
Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward. |
2007 |
Neuropsychopharmacology |
pmid:17406653
|
Kopczyńska B |
The contribution of VR1 and CB1 receptors and the role of the afferent vagal pathway in modelling of cardio-respiratory effects of anandamide in rats. |
2007 |
Life Sci. |
pmid:17379256
|
Ferrer B et al. |
Regulation of brain anandamide by acute administration of ethanol. |
2007 |
Biochem. J. |
pmid:17302558
|
Naidu PS et al. |
Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality. |
2007 |
Psychopharmacology (Berl.) |
pmid:17279376
|
Sun Y et al. |
Cannabinoid activation of PPAR alpha; a novel neuroprotective mechanism. |
2007 |
Br. J. Pharmacol. |
pmid:17906680
|
Lam PM et al. |
Activation of recombinant human TRPV1 receptors expressed in SH-SY5Y human neuroblastoma cells increases [Ca(2+)](i), initiates neurotransmitter release and promotes delayed cell death. |
2007 |
J. Neurochem. |
pmid:17442052
|
Köfalvi A et al. |
Anandamide and NADA bi-directionally modulate presynaptic Ca2+ levels and transmitter release in the hippocampus. |
2007 |
Br. J. Pharmacol. |
pmid:17435795
|
Lam FF et al. |
Pharmacological characterization of receptor types mediating the dilator action of anandamide on blood vessels of the rat knee joint. |
2007 |
Life Sci. |
pmid:17275857
|
Sharkey KA et al. |
Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret. |
2007 |
Eur. J. Neurosci. |
pmid:17459108
|
Coopman K et al. |
Temporal variation in CB2R levels following T lymphocyte activation: evidence that cannabinoids modulate CXCL12-induced chemotaxis. |
2007 |
Int. Immunopharmacol. |
pmid:17276894
|
Shivachar AC |
Cannabinoids inhibit sodium-dependent, high-affinity excitatory amino acid transport in cultured rat cortical astrocytes. |
2007 |
Biochem. Pharmacol. |
pmid:17445778
|
Orliac ML et al. |
Increases in vanilloid TRPV1 receptor protein and CGRP content during endotoxemia in rats. |
2007 |
Eur. J. Pharmacol. |
pmid:17482593
|
Michalski CW et al. |
Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis. |
2007 |
Gastroenterology |
pmid:17484889
|
Ghasemi M et al. |
Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats. |
2007 |
Br. J. Pharmacol. |
pmid:17486141
|
Borsani E et al. |
AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain. |
2007 |
Brain Res. |
pmid:17459353
|
Sit SY et al. |
Novel inhibitors of fatty acid amide hydrolase. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17459705
|
Lory P and Chemin J |
Towards the discovery of novel T-type calcium channel blockers. |
2007 |
Expert Opin. Ther. Targets |
pmid:17465728
|
Ryan D et al. |
Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. |
2007 |
Eur. J. Neurosci. |
pmid:17419758
|
Gonthier MP et al. |
Identification of endocannabinoids and related compounds in human fat cells. |
2007 |
Obesity (Silver Spring) |
pmid:17426318
|
Wang H et al. |
Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation. |
2007 |
Prostaglandins Other Lipid Mediat. |
pmid:17259073
|
Adermark L and Lovinger DM |
Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step. |
2007 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18077376
|
Lemak MS et al. |
Cannabinoid regulation in identified synapse of terrestrial snail. |
2007 |
Eur. J. Neurosci. |
pmid:18028114
|
Béquet F et al. |
CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus. |
2007 |
Eur. J. Neurosci. |
pmid:18052990
|
Rettori V et al. |
Endocannabinoids in TNF-alpha and ethanol actions. |
2007 |
Neuroimmunomodulation |
pmid:18073513
|
Peroni RN et al. |
Participation of CGRP and prostanoids in the sex-linked differences of vascular anandamide effects in mesenteric beds of Sprague-Dawley rats. |
2007 |
Eur. J. Pharmacol. |
pmid:17169358
|
Moreira FA et al. |
Anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaqueductal gray. |
2007 |
Neuropharmacology |
pmid:17156799
|
Jin XH et al. |
Discovery and characterization of a Ca2+-independent phosphatidylethanolamine N-acyltransferase generating the anandamide precursor and its congeners. |
2007 |
J. Biol. Chem. |
pmid:17158102
|
Rossi G et al. |
Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells. |
2007 |
Endocrinology |
pmid:17110429
|
Cross-Mellor SK et al. |
Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. |
2007 |
Psychopharmacology (Berl.) |
pmid:17111174
|
Ronco AM et al. |
Anandamide inhibits endothelin-1 production by human cultured endothelial cells: a new vascular action of this endocannabinoid. |
2007 |
Pharmacology |
pmid:17114903
|
Bourne C et al. |
Novel, potent THC/anandamide (hybrid) analogs. |
2007 |
Bioorg. Med. Chem. |
pmid:17827022
|
Russo R et al. |
Synergistic antinociception by the cannabinoid receptor agonist anandamide and the PPAR-alpha receptor agonist GW7647. |
2007 |
Eur. J. Pharmacol. |
pmid:17434479
|
Wheal AJ et al. |
Effects of chronic nitric oxide synthase inhibition on the cardiovascular responses to cannabinoids in vivo and in vitro. |
2007 |
Br. J. Pharmacol. |
pmid:17245361
|
Bátkai S et al. |
Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase. |
2007 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:17434980
|
Harada N and Okajima K |
Effect of topical application of capsaicin and its related compounds on dermal insulin-like growth factor-I levels in mice and on facial skin elasticity in humans. |
2007 |
Growth Horm. IGF Res. |
pmid:17307377
|
Romero FA et al. |
Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. |
2007 |
J. Med. Chem. |
pmid:17279740
|
McCollum L et al. |
Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17379772
|
Wang Y et al. |
Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in Wistar rats fed a high-salt diet. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17308041
|
Snider NT et al. |
Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17272674
|
Solinas M et al. |
The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17210800
|
Côté M et al. |
Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men. |
2007 |
Int J Obes (Lond) |
pmid:17224929
|
Smita K et al. |
Anandamide: an update. |
2007 |
Fundam Clin Pharmacol |
pmid:17227440
|
Matas D et al. |
Anandamide protects from low serum-induced apoptosis via its degradation to ethanolamine. |
2007 |
J. Biol. Chem. |
pmid:17227767
|
Wise LE et al. |
Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors. |
2007 |
Eur. J. Pharmacol. |
pmid:17217945
|
Hsu SS et al. |
Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells. |
2007 |
Toxicology |
pmid:17222495
|
Harada N and Okajima K |
Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats. |
2007 |
Dig. Dis. Sci. |
pmid:17211693
|
Pisanti S et al. |
Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacy. |
2007 |
J. Cell. Physiol. |
pmid:17192847
|
Ekins S et al. |
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. |
2007 |
Drug Metab. Dispos. |
pmid:17194716
|
Schreiber D et al. |
Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry. |
2007 |
Anal. Biochem. |
pmid:17196922
|
Kreutz S et al. |
Cannabinoids and neuronal damage: differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures. |
2007 |
Exp. Neurol. |
pmid:17010339
|
Malfitano AM et al. |
Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cells. |
2007 |
Immunol. Lett. |
pmid:17360047
|
Blankman JL et al. |
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. |
2007 |
Chem. Biol. |
pmid:18096503
|
Kracke GR et al. |
The cannabinoid receptor agonists, anandamide and WIN 55,212-2, do not directly affect mu opioid receptors expressed in Xenopus oocytes. |
2007 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:17960365
|
Thomas KC et al. |
Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17332266
|
Battista N et al. |
The endocannabinoid system in neurodegeneration. |
2006 Sep-Dec |
Ital. J. Biochem. |
pmid:17274532
|
Lynch DL and Reggio PH |
Cannabinoid CB1 receptor recognition of endocannabinoids via the lipid bilayer: molecular dynamics simulations of CB1 transmembrane helix 6 and anandamide in a phospholipid bilayer. |
2006 Jul-Aug |
J. Comput. Aided Mol. Des. |
pmid:17106765
|
Dickason-Chesterfield AK et al. |
Pharmacological characterization of endocannabinoid transport and fatty acid amide hydrolase inhibitors. |
2006 Jul-Aug |
Cell. Mol. Neurobiol. |
pmid:16736384
|
Kukushkin ML et al. |
Role of cannabinoid receptor agonists in mechanisms of suppression of central pain syndrome. |
2006 |
Bull. Exp. Biol. Med. |
pmid:17369898
|
Szabo B et al. |
Depolarization-induced retrograde synaptic inhibition in the mouse cerebellar cortex is mediated by 2-arachidonoylglycerol. |
2006 |
J. Physiol. (Lond.) |
pmid:16973696
|
Wiley JL et al. |
Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice. |
2006 |
Life Sci. |
pmid:16978656
|
Thors L and Fowler CJ |
Is there a temperature-dependent uptake of anandamide into cells? |
2006 |
Br. J. Pharmacol. |
pmid:16865094
|
Nilsson O et al. |
The cannabinoid agonist WIN 55,212-2 inhibits TNF-alpha-induced neutrophil transmigration across ECV304 cells. |
2006 |
Eur. J. Pharmacol. |
pmid:16928371
|
Schuel H |
Tuning the oviduct to the anandamide tone. |
2006 |
J. Clin. Invest. |
pmid:16886056
|
Kasai HF et al. |
Studies on high-energy collision-induced dissociation of endogenous cannabinoids: 2-arachidonoylglycerol and n-arachidonoylethanolamide in FAB-mass spectrometry. |
2006 |
Anal Sci |
pmid:16837740
|
Murillo-RodrÃguez E et al. |
Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. |
2006 |
FEBS Lett. |
pmid:16844117
|
Liu J et al. |
A biosynthetic pathway for anandamide. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16938887
|
Kudo R and Hatake K |
[Effect of ethanol on anandamide-induced sensory nerve dependent vasorelaxation]. |
2006 |
Nihon Arukoru Yakubutsu Igakkai Zasshi |
pmid:17313058
|
Romano MR and Lograno MD |
Cannabinoid agonists induce relaxation in the bovine ophthalmic artery: evidences for CB1 receptors, nitric oxide and potassium channels. |
2006 |
Br. J. Pharmacol. |
pmid:16474412
|
Tuccinardi T et al. |
Cannabinoid CB2/CB1 selectivity. Receptor modeling and automated docking analysis. |
2006 |
J. Med. Chem. |
pmid:16451064
|
Monterrubio S and Solowij N |
Chronic stress and adaptation. |
2006 |
Am J Psychiatry |
pmid:16513893
|
Bari M et al. |
New insights into endocannabinoid degradation and its therapeutic potential. |
2006 |
Mini Rev Med Chem |
pmid:16515464
|
Overton HA et al. |
Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. |
2006 |
Cell Metab. |
pmid:16517404
|
Matias I et al. |
Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. |
2006 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:17011761
|
Bari M et al. |
Effect of lipid rafts on Cb2 receptor signaling and 2-arachidonoyl-glycerol metabolism in human immune cells. |
2006 |
J. Immunol. |
pmid:17015679
|
Tan B et al. |
Targeted lipidomics: discovery of new fatty acyl amides. |
2006 |
AAPS J |
pmid:17025263
|
Gough NR |
Focus issue: signaling lipids. |
2006 |
Sci. STKE |
pmid:16467192
|
Migliarini B et al. |
Endocannabinoid system in Xenopus laevis development: CB1 receptor dynamics. |
2006 |
FEBS Lett. |
pmid:16519888
|
Wang J et al. |
Functional analysis of the purified anandamide-generating phospholipase D as a member of the metallo-beta-lactamase family. |
2006 |
J. Biol. Chem. |
pmid:16527816
|
Bortolato M et al. |
Anxiolytic-like properties of the anandamide transport inhibitor AM404. |
2006 |
Neuropsychopharmacology |
pmid:16541083
|
Maccarrone M et al. |
Regulation by cannabinoid receptors of anandamide transport across the blood-brain barrier and through other endothelial cells. |
2006 |
Thromb. Haemost. |
pmid:16543970
|
Siegmund SV et al. |
Fatty acid amide hydrolase determines anandamide-induced cell death in the liver. |
2006 |
J. Biol. Chem. |
pmid:16418162
|
Salo OM et al. |
3D-QSAR studies on cannabinoid CB1 receptor agonists: G-protein activation as biological data. |
2006 |
J. Med. Chem. |
pmid:16420041
|
Kohro S et al. |
Anandamide absorption by direct hemoperfusion with polymixin B-immobilized fiber improves the prognosis and organ failure assessment score in patients with sepsis. |
2006 |
J Anesth |
pmid:16421670
|
Rawls SM et al. |
Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats. |
2006 |
Pharmacol. Biochem. Behav. |
pmid:16647109
|
Parkkari T et al. |
Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide. |
2006 |
Bioorg. Med. Chem. |
pmid:16644227
|
McFarland MJ et al. |
Detergent-resistant membrane microdomains in the disposition of the lipid signaling molecule anandamide. |
2006 |
AAPS J |
pmid:16584138
|
Varvel SA et al. |
Fatty acid amide hydrolase (-/-) mice exhibit an increased sensitivity to the disruptive effects of anandamide or oleamide in a working memory water maze task. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16352706
|
Wei BQ et al. |
A second fatty acid amide hydrolase with variable distribution among placental mammals. |
2006 |
J. Biol. Chem. |
pmid:17015445
|
Rösch S et al. |
R(+)-methanandamide and other cannabinoids induce the expression of cyclooxygenase-2 and matrix metalloproteinases in human nonpigmented ciliary epithelial cells. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16330497
|
Sade H et al. |
Activation of large-conductance, Ca2+-activated K+ channels by cannabinoids. |
2006 |
Am. J. Physiol., Cell Physiol. |
pmid:16107501
|
Kopczyńska B and Szereda-Przestaszewska M |
Supranodose vagotomy eliminates anandamide-evoked cardiorespiratory depression in anaesthetized rats. |
2006 |
Respir Physiol Neurobiol |
pmid:16144778
|
Wang H et al. |
Fatty acid amide hydrolase deficiency limits early pregnancy events. |
2006 |
J. Clin. Invest. |
pmid:16886060
|
Tzavara ET et al. |
Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications. |
2006 |
Biol. Psychiatry |
pmid:16199010
|
Moezi L et al. |
Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB(1) and VR(1) receptors. |
2006 |
Br. J. Pharmacol. |
pmid:17043671
|
Eljaschewitsch E et al. |
The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. |
2006 |
Neuron |
pmid:16387640
|
Yang YY et al. |
Roles of anandamide in the hepatic microcirculation in cirrhotic rats. |
2006 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:16407591
|
Appendino G et al. |
First "hybrid" ligands of vanilloid TRPV1 and cannabinoid CB2 receptors and non-polyunsaturated fatty acid-derived CB2-selective ligands. |
2006 |
FEBS Lett. |
pmid:16406364
|