Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Orthostatic Intolerance D054971 1 associated lipids
Schistosomiasis japonica D012554 3 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Acute Pain D059787 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Wang H et al. Differential G protein-coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:14645706
Grimaldi P et al. The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19541620
Morena M et al. Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25489086
Alger BE Endocannabinoids: getting the message across. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15173576
Walker JM et al. Pain modulation by release of the endogenous cannabinoid anandamide. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10518599
Schuel H et al. Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8052642
Scorticati C et al. The effect of anandamide on prolactin secretion is modulated by estrogen. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:12578974
Felder CC et al. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:8395053
Hill MN et al. Endogenous cannabinoid signaling is essential for stress adaptation. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20439721
Devane WA and Axelrod J Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8022836
Cravatt BF et al. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11470906
Mechoulam R and Deutsch DG Toward an anandamide transporter. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:16314567
Long JZ et al. Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19918051
Schmid PC et al. Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9108127
Glaser ST et al. Evidence against the presence of an anandamide transporter. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:12655057
Collin C et al. Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7479747
Dinh TP et al. Brain monoglyceride lipase participating in endocannabinoid inactivation. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:12136125
Klein TW et al. The cannabinoid system and cytokine network. 2000 Proc. Soc. Exp. Biol. Med. pmid:10998193
Calignano A et al. A role for the endogenous cannabinoid system in the peripheral control of pain initiation. 2000 Prog. Brain Res. pmid:11098711
Ueda N et al. N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA). 2010 Prog. Lipid Res. pmid:20152858