Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Oka S et al. Depolarization-induced rapid generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in rat brain synaptosomes. 2007 J. Biochem. pmid:17339228
D'Argenio G et al. Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. 2007 J. Mol. Med. pmid:17396241
Holt S et al. Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin. 2007 Eur. J. Pharmacol. pmid:17397826
Mahler SV et al. Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward. 2007 Neuropsychopharmacology pmid:17406653
Lam PM et al. Activation of recombinant human TRPV1 receptors expressed in SH-SY5Y human neuroblastoma cells increases [Ca(2+)](i), initiates neurotransmitter release and promotes delayed cell death. 2007 J. Neurochem. pmid:17442052
De Petrocellis L et al. Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids. 2007 Exp. Cell Res. pmid:17428469
Richardson D et al. Quantitative profiling of endocannabinoids and related compounds in rat brain using liquid chromatography-tandem electrospray ionization mass spectrometry. 2007 Anal. Biochem. pmid:17141174
Starowicz K et al. Biochemistry and pharmacology of endovanilloids. 2007 Pharmacol. Ther. pmid:17349697
Köfalvi A et al. Anandamide and NADA bi-directionally modulate presynaptic Ca2+ levels and transmitter release in the hippocampus. 2007 Br. J. Pharmacol. pmid:17435795
Brizzi A et al. Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors. 2007 Bioorg. Med. Chem. pmid:17561406
Hill MN et al. Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity. 2007 J. Neurochem. pmid:17561935
Leweke FM et al. Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use. 2007 Schizophr. Res. pmid:17566707
Ali AB Presynaptic Inhibition of GABAA receptor-mediated unitary IPSPs by cannabinoid receptors at synapses between CCK-positive interneurons in rat hippocampus. 2007 J. Neurophysiol. pmid:17567776
Fischbach T et al. Effects of anandamide and noxious heat on intracellular calcium concentration in nociceptive drg neurons of rats. 2007 J. Neurophysiol. pmid:17581853
Saitoh C et al. The differential contractile responses to capsaicin and anandamide in muscle strips isolated from the rat urinary bladder. 2007 Eur. J. Pharmacol. pmid:17586490
Cavuoto P et al. Effects of cannabinoid receptors on skeletal muscle oxidative pathways. 2007 Mol. Cell. Endocrinol. pmid:17270342
Duarte CD et al. Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors. 2007 Bioorg. Med. Chem. pmid:17275312
Lam FF et al. Pharmacological characterization of receptor types mediating the dilator action of anandamide on blood vessels of the rat knee joint. 2007 Life Sci. pmid:17275857
Sharkey KA et al. Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret. 2007 Eur. J. Neurosci. pmid:17459108
Coopman K et al. Temporal variation in CB2R levels following T lymphocyte activation: evidence that cannabinoids modulate CXCL12-induced chemotaxis. 2007 Int. Immunopharmacol. pmid:17276894
Shivachar AC Cannabinoids inhibit sodium-dependent, high-affinity excitatory amino acid transport in cultured rat cortical astrocytes. 2007 Biochem. Pharmacol. pmid:17445778
Orliac ML et al. Increases in vanilloid TRPV1 receptor protein and CGRP content during endotoxemia in rats. 2007 Eur. J. Pharmacol. pmid:17482593
Michalski CW et al. Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis. 2007 Gastroenterology pmid:17484889
Ghasemi M et al. Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats. 2007 Br. J. Pharmacol. pmid:17486141
Borsani E et al. AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain. 2007 Brain Res. pmid:17459353
Oz M et al. The endogenous cannabinoid anandamide inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes. 2007 J. Pharmacol. Exp. Ther. pmid:17682128
Mulè F et al. Involvement of CB1 and CB2 receptors in the modulation of cholinergic neurotransmission in mouse gastric preparations. 2007 Pharmacol. Res. pmid:17656103
Iuvone T et al. Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro. 2007 J. Mol. Med. pmid:17639288
Eisenstein TK et al. Anandamide and Delta9-tetrahydrocannabinol directly inhibit cells of the immune system via CB2 receptors. 2007 J. Neuroimmunol. pmid:17640739
Pakdeechote P et al. Cannabinoids inhibit noradrenergic and purinergic sympathetic cotransmission in the rat isolated mesenteric arterial bed. 2007 Br. J. Pharmacol. pmid:17641668
Tanaka M et al. The mRNA expression of fatty acid amide hydrolase in human whole blood correlates with sepsis. 2007 J. Endotoxin Res. pmid:17621544
Després JP The endocannabinoid system: a new target for the regulation of energy balance and metabolism. 2007 Crit Pathw Cardiol pmid:17667864
Thors L et al. The 'specific' tyrosine kinase inhibitor genistein inhibits the enzymic hydrolysis of anandamide: implications for anandamide uptake. 2007 Br. J. Pharmacol. pmid:17325653
Bátkai S et al. Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury. 2007 FASEB J. pmid:17327359
Cippitelli A et al. The anandamide transport inhibitor AM404 reduces ethanol self-administration. 2007 Eur. J. Neurosci. pmid:17650118
Wang H et al. Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation. 2007 Prostaglandins Other Lipid Mediat. pmid:17259073
Adermark L and Lovinger DM Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:18077376
Lemak MS et al. Cannabinoid regulation in identified synapse of terrestrial snail. 2007 Eur. J. Neurosci. pmid:18028114
Béquet F et al. CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus. 2007 Eur. J. Neurosci. pmid:18052990
Rettori V et al. Endocannabinoids in TNF-alpha and ethanol actions. 2007 Neuroimmunomodulation pmid:18073513
Varvel SA et al. Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. 2007 Neuropsychopharmacology pmid:17047668
Sarchielli P et al. Endocannabinoids in chronic migraine: CSF findings suggest a system failure. 2007 Neuropsychopharmacology pmid:17119542
Chemin J et al. Chemical determinants involved in anandamide-induced inhibition of T-type calcium channels. 2007 J. Biol. Chem. pmid:17121818
Ghasemi M et al. Anandamide improves the impaired nitric oxide-mediated neurogenic relaxation of the corpus cavernosum in diabetic rats: involvement of cannabinoid CB1 and vanilloid VR1 receptors. 2007 BJU Int. pmid:17850365
Cisneros JA et al. Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase. 2007 J. Med. Chem. pmid:17764163
Vandevoorde S et al. Lack of selectivity of URB602 for 2-oleoylglycerol compared to anandamide hydrolysis in vitro. 2007 Br. J. Pharmacol. pmid:17143303
Evans RM et al. Chronic exposure of sensory neurones to increased levels of nerve growth factor modulates CB1/TRPV1 receptor crosstalk. 2007 Br. J. Pharmacol. pmid:17700720
Wheal AJ et al. Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats. 2007 Br. J. Pharmacol. pmid:17700721
Matias I et al. Role and regulation of acylethanolamides in energy balance: focus on adipocytes and beta-cells. 2007 Br. J. Pharmacol. pmid:17704823
Peroni RN et al. Participation of CGRP and prostanoids in the sex-linked differences of vascular anandamide effects in mesenteric beds of Sprague-Dawley rats. 2007 Eur. J. Pharmacol. pmid:17169358
Herradón E et al. Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta. 2007 Br. J. Pharmacol. pmid:17704831
Moreira FA et al. Anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaqueductal gray. 2007 Neuropharmacology pmid:17156799
Smid SD et al. The endocannabinoids anandamide and 2-arachidonoylglycerol inhibit cholinergic contractility in the human colon. 2007 Eur. J. Pharmacol. pmid:17706636
Jin XH et al. Discovery and characterization of a Ca2+-independent phosphatidylethanolamine N-acyltransferase generating the anandamide precursor and its congeners. 2007 J. Biol. Chem. pmid:17158102
Hanus LO Discovery and isolation of anandamide and other endocannabinoids. 2007 Chem. Biodivers. pmid:17712821
Okamoto Y et al. Biosynthetic pathways of the endocannabinoid anandamide. 2007 Chem. Biodivers. pmid:17712822
Rossi G et al. Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells. 2007 Endocrinology pmid:17110429
Yuece B et al. Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristaltic reflex. 2007 Neurogastroenterol. Motil. pmid:17727394
Cross-Mellor SK et al. Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. 2007 Psychopharmacology (Berl.) pmid:17111174
Bourne C et al. Novel, potent THC/anandamide (hybrid) analogs. 2007 Bioorg. Med. Chem. pmid:17827022
Russo R et al. Synergistic antinociception by the cannabinoid receptor agonist anandamide and the PPAR-alpha receptor agonist GW7647. 2007 Eur. J. Pharmacol. pmid:17434479
Bátkai S et al. Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17434980
Harada N and Okajima K Effect of topical application of capsaicin and its related compounds on dermal insulin-like growth factor-I levels in mice and on facial skin elasticity in humans. 2007 Growth Horm. IGF Res. pmid:17307377
Romero FA et al. Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. 2007 J. Med. Chem. pmid:17279740
Hiley CR and Hoi PM Oleamide: a fatty acid amide signaling molecule in the cardiovascular system? 2007 Cardiovasc Drug Rev pmid:17445087
McCollum L et al. Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells. 2007 J. Pharmacol. Exp. Ther. pmid:17379772
Wang Y et al. Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in Wistar rats fed a high-salt diet. 2007 J. Pharmacol. Exp. Ther. pmid:17308041
Nucci C et al. Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats. 2007 Invest. Ophthalmol. Vis. Sci. pmid:17591864
Snider NT et al. Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. 2007 J. Pharmacol. Exp. Ther. pmid:17272674
Murakami T et al. Antibacterial cathelicidin peptide CAP11 suppresses the anandamide production from lipopolysaccharide-stimulated mononuclear phagocytes. 2007 FEBS Lett. pmid:17184778
Gasperi V et al. Endocannabinoids in adipocytes during differentiation and their role in glucose uptake. 2007 Cell. Mol. Life Sci. pmid:17187172
Côté M et al. Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men. 2007 Int J Obes (Lond) pmid:17224929
Smita K et al. Anandamide: an update. 2007 Fundam Clin Pharmacol pmid:17227440
Braida D et al. 5-HT1A receptors are involved in the anxiolytic effect of Delta9-tetrahydrocannabinol and AM 404, the anandamide transport inhibitor, in Sprague-Dawley rats. 2007 Eur. J. Pharmacol. pmid:17116299
Matas D et al. Anandamide protects from low serum-induced apoptosis via its degradation to ethanolamine. 2007 J. Biol. Chem. pmid:17227767
Castelli MP et al. Dysregulation of the endogenous cannabinoid system in adult rats prenatally treated with the cannabinoid agonist WIN 55,212-2. 2007 Eur. J. Pharmacol. pmid:17644084
Wise LE et al. Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors. 2007 Eur. J. Pharmacol. pmid:17217945
DeMorrow S et al. Opposing actions of endocannabinoids on cholangiocarcinoma growth: recruitment of Fas and Fas ligand to lipid rafts. 2007 J. Biol. Chem. pmid:17329257
Hsu SS et al. Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells. 2007 Toxicology pmid:17222495
Ade KK and Lovinger DM Anandamide regulates postnatal development of long-term synaptic plasticity in the rat dorsolateral striatum. 2007 J. Neurosci. pmid:17329438
Harada N and Okajima K Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats. 2007 Dig. Dis. Sci. pmid:17211693
Malfitano AM et al. Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cells. 2007 Immunol. Lett. pmid:17360047
Blankman JL et al. A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. 2007 Chem. Biol. pmid:18096503
Stengel PW et al. Inhaled anandamide reduces leukotriene D4-induced airway obstruction in guinea pigs. 2007 Eur. J. Pharmacol. pmid:17166495
Imming P Fatty pain cures. 2007 Chem. Biol. pmid:18096498
King AR et al. URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. 2007 Chem. Biol. pmid:18096504
Hillard CJ et al. Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolase. 2007 J. Mol. Neurosci. pmid:17901541
Opitz CA et al. Production of the endocannabinoids anandamide and 2-arachidonoylglycerol by endothelial progenitor cells. 2007 FEBS Lett. pmid:17904123
Joshi SR Endocannabinoid system--a novel target for cardiometabolic risk. 2007 J Assoc Physicians India pmid:17879500
Mitchell VA et al. Actions of the endocannabinoid transport inhibitor AM404 in neuropathic and inflammatory pain models. 2007 Clin. Exp. Pharmacol. Physiol. pmid:17880375
Romano MR and Lograno MD Evidence for the involvement of cannabinoid CB1 receptors in the bimatoprost-induced contractions on the human isolated ciliary muscle. 2007 Invest. Ophthalmol. Vis. Sci. pmid:17652738
Bentzen PJ and Lang F Effect of anandamide on erythrocyte survival. 2007 Cell. Physiol. Biochem. pmid:17975305
Mukhopadhyay S and Tulis DA Endocannabinoid regulation of matrix metalloproteinases: implications in ischemic stroke. 2007 Cardiovasc Hematol Agents Med Chem pmid:17979695
Soria-Gómez E et al. Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus. 2007 Br. J. Pharmacol. pmid:17549045
Dainese E et al. Modulation of the endocannabinoid system by lipid rafts. 2007 Curr. Med. Chem. pmid:17979719
Kim SR et al. Roles of transient receptor potential vanilloid subtype 1 and cannabinoid type 1 receptors in the brain: neuroprotection versus neurotoxicity. 2007 Mol. Neurobiol. pmid:17917113
Hornig B Endothelial vasodilatory cannabinoid receptor in the human pulmonary artery: a future option in the therapy of pulmonary hypertension? 2007 J. Hypertens. pmid:17921811
Kozłowska H et al. Identification of the vasodilatory endothelial cannabinoid receptor in the human pulmonary artery. 2007 J. Hypertens. pmid:17921818
Kracke GR et al. The cannabinoid receptor agonists, anandamide and WIN 55,212-2, do not directly affect mu opioid receptors expressed in Xenopus oocytes. 2007 Naunyn Schmiedebergs Arch. Pharmacol. pmid:17960365
Thomas KC et al. Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. 2007 J. Pharmacol. Exp. Ther. pmid:17332266