| MeSH term | MeSH ID | Detail |
|---|---|---|
| Weight Gain | D015430 | 101 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Obesity | D009765 | 29 associated lipids |
| Bradycardia | D001919 | 13 associated lipids |
| Urinary Bladder Diseases | D001745 | 4 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kudo R and Hatake K | [Effect of ethanol on anandamide-induced sensory nerve dependent vasorelaxation]. | 2006 | Nihon Arukoru Yakubutsu Igakkai Zasshi | pmid:17313058 |
| Hayase T et al. | Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity. | 2001 | Nihon Arukoru Yakubutsu Igakkai Zasshi | pmid:11828716 |
| Kudo R and Hatake K | [Effect of ethanol on anandamide-induced sensory nerve dependent vasorelaxation (the second report)]. | 2008 | Nihon Arukoru Yakubutsu Igakkai Zasshi | pmid:18646646 |
| Yamaguchi Y et al. | [Surgical stress]. | 2005 | Nihon Geka Gakkai Zasshi | pmid:16045189 |
| Kamei J et al. | [Sensitization of cough sensitivity through activation of C-and/or Adelta fibers]. | 2008 | Nippon Yakurigaku Zasshi | pmid:18552444 |
| Romero TR et al. | The neuronal NO synthase participation in the peripheral antinociception mechanism induced by several analgesic drugs. | 2011 | Nitric Oxide | pmid:21875681 |
| Haas MJ et al. | Inhibition of apolipoprotein A-I gene expression by obesity-associated endocannabinoids. | 2012 | Obesity (Silver Spring) | pmid:22016100 |
| Gonthier MP et al. | Identification of endocannabinoids and related compounds in human fat cells. | 2007 | Obesity (Silver Spring) | pmid:17426318 |
| Engeli S et al. | Influence of dietary fat intake on the endocannabinoid system in lean and obese subjects. | 2014 | Obesity (Silver Spring) | pmid:24616451 |
| Starowicz KM et al. | Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet. | 2008 | Obesity (Silver Spring) | pmid:18239598 |
| Karaliota S et al. | Anandamide increases the differentiation of rat adipocytes and causes PPARgamma and CB1 receptor upregulation. | 2009 | Obesity (Silver Spring) | pmid:19543211 |
| Zelber-Sagi S et al. | Serum levels of endocannabinoids are independently associated with nonalcoholic fatty liver disease. | 2017 | Obesity (Silver Spring) | pmid:27863097 |
| Abdulnour J et al. | Circulating endocannabinoids in insulin sensitive vs. insulin resistant obese postmenopausal women. A MONET group study. | 2014 | Obesity (Silver Spring) | pmid:23616305 |
| Engeli S et al. | Peripheral endocannabinoid system activity in patients treated with sibutramine. | 2008 | Obesity (Silver Spring) | pmid:18356837 |
| Alvheim AR et al. | Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity. | 2012 | Obesity (Silver Spring) | pmid:22334255 |
| Tong S et al. | Diagnostic accuracy of maternal serum macrophage inhibitory cytokine-1 and pregnancy-associated plasma protein-A at 6-10 weeks of gestation to predict miscarriage. | 2012 | Obstet Gynecol | pmid:22525911 |
| Bernabò N et al. | Systems biology analysis of the endocannabinoid system reveals a scale-free network with distinct roles for anandamide and 2-arachidonoylglycerol. | 2013 | OMICS | pmid:24117401 |
| Orellana-Serradell O et al. | Proapoptotic effect of endocannabinoids in prostate cancer cells. | 2015 | Oncol. Rep. | pmid:25606819 |
| Scholl A et al. | Inhibition of interleukin-1β-induced endothelial tissue factor expression by the synthetic cannabinoid WIN 55,212-2. | 2016 | Oncotarget | pmid:27556861 |
| Ravi J et al. | FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway. | 2014 | Oncotarget | pmid:24811863 |
| Palkovits M | [The brain and the pain: neurotransmitters and neuronal pathways of pain perception and response]. | 2000 | Orv Hetil | pmid:11184247 |
| Jia J et al. | Anandamide protects HT22 cells exposed to hydrogen peroxide by inhibiting CB1 receptor-mediated type 2 NADPH oxidase. | 2014 | Oxid Med Cell Longev | pmid:25136404 |
| Farquhar-Smith WP et al. | Attenuation of nerve growth factor-induced visceral hyperalgesia via cannabinoid CB(1) and CB(2)-like receptors. | 2002 | Pain | pmid:12031775 |
| Horvath G et al. | The role of TRPV1 receptors in the antinociceptive effect of anandamide at spinal level. | 2008 | Pain | pmid:17533116 |
| Lichtman AH et al. | Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia. | 2004 | Pain | pmid:15157693 |
| Guindon J et al. | Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain. | 2006 | Pain | pmid:16480822 |
| Jaggar SI et al. | The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. | 1998 | Pain | pmid:9696473 |
| Butler RK et al. | Endocannabinoid-mediated enhancement of fear-conditioned analgesia in rats: opioid receptor dependency and molecular correlates. | 2008 | Pain | pmid:19004548 |
| Richardson JD et al. | Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. | 1998 | Pain | pmid:9539680 |
| Kenessey I et al. | Revisiting CB1 receptor as drug target in human melanoma. | 2012 | Pathol. Oncol. Res. | pmid:22447182 |
| Krishtal O et al. | The agonists for nociceptors are ubiquitous, but the modulators are specific: P2X receptors in the sensory neurons are modulated by cannabinoids. | 2006 | Pflugers Arch. | pmid:16741755 |
| Laine K et al. | Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits. | 2001 | Pharm. Res. | pmid:11451037 |
| Pate DW et al. | Effects of topical alpha-substituted anandamides on intraocular pressure in normotensive rabbits. | 1997 | Pharm. Res. | pmid:9453062 |
| Sadhasivam S et al. | Novel associations between FAAH genetic variants and postoperative central opioid-related adverse effects. | 2015 | Pharmacogenomics J. | pmid:25558980 |
| Fowler CJ et al. | The endocannabinoid signaling system: pharmacological and therapeutic aspects. | 2005 | Pharmacol. Biochem. Behav. | pmid:15935456 |
| Smith FL et al. | Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats. | 1998 | Pharmacol. Biochem. Behav. | pmid:9610941 |
| Wiley JL | Cannabis: discrimination of "internal bliss"? | 1999 | Pharmacol. Biochem. Behav. | pmid:10515300 |
| Romero J et al. | Changes in rat brain cannabinoid binding sites after acute or chronic exposure to their endogenous agonist, anandamide, or to delta 9-tetrahydrocannabinol. | 1995 | Pharmacol. Biochem. Behav. | pmid:7675852 |
| Wiley JL and Burston JJ | Chronic Delta9-tetrahydrocannabinol during adolescence increases sensitivity to subsequent cannabinoid effects in delayed nonmatch-to-position in rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:19941884 |
| Herrera-SolÃs A et al. | Acute and subchronic administration of anandamide or oleamide increases REM sleep in rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:20056119 |
| Rawls SM et al. | Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats. | 2006 | Pharmacol. Biochem. Behav. | pmid:16647109 |
| Crawley JN et al. | Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents. | 1993 | Pharmacol. Biochem. Behav. | pmid:7906042 |
| Wiley JL et al. | Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. | 1997 | Pharmacol. Biochem. Behav. | pmid:9408225 |
| Wenger T et al. | The effects of prenatally administered endogenous cannabinoid on rat offspring. | 1997 | Pharmacol. Biochem. Behav. | pmid:9300616 |
| Reyes-Cabello C et al. | Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration. | 2012 | Pharmacol. Biochem. Behav. | pmid:22133635 |
| Tuboly G et al. | The antinociceptive interaction of anandamide and adenosine at the spinal level. | 2009 | Pharmacol. Biochem. Behav. | pmid:18760296 |
| Sulcova E et al. | Biphasic effects of anandamide. | 1998 | Pharmacol. Biochem. Behav. | pmid:9476980 |
| Stefano GB et al. | 2-arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1. | 2000 | Pharmacol. Res. | pmid:10987990 |
| Nicolussi S et al. | Guineensine is a novel inhibitor of endocannabinoid uptake showing cannabimimetic behavioral effects in BALB/c mice. | 2014 | Pharmacol. Res. | pmid:24412246 |
| Maione S et al. | Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics. | 2013 | Pharmacol. Res. | pmid:23911581 |