| MeSH term | MeSH ID | Detail |
|---|---|---|
| Weight Gain | D015430 | 101 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Obesity | D009765 | 29 associated lipids |
| Bradycardia | D001919 | 13 associated lipids |
| Urinary Bladder Diseases | D001745 | 4 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang H et al. | Differential G protein-coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:14645706 |
| Piomelli D et al. | Structural determinants for recognition and translocation by the anandamide transporter. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10318965 |
| Brown WH et al. | Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22912404 |
| Scorticati C et al. | The inhibitory effect of anandamide on luteinizing hormone-releasing hormone secretion is reversed by estrogen. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15280536 |
| Grimaldi P et al. | The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19541620 |
| Alger BE | Endocannabinoids: getting the message across. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15173576 |
| Liu J et al. | A biosynthetic pathway for anandamide. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16938887 |
| Járai Z et al. | Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570211 |
| Boger DL et al. | Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10805767 |
| De Petrocellis L et al. | The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9653194 |
| Fegley D et al. | Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15138300 |
| Adermark L and Lovinger DM | Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18077376 |
| Walker JM et al. | Pain modulation by release of the endogenous cannabinoid anandamide. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10518599 |
| Schuel H et al. | Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8052642 |
| Scorticati C et al. | The effect of anandamide on prolactin secretion is modulated by estrogen. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12578974 |
| Felder CC et al. | Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. | 1993 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8395053 |
| Das SK et al. | Cannabinoid ligand-receptor signaling in the mouse uterus. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7753807 |
| Facci L et al. | Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7724569 |
| Hill MN et al. | Endogenous cannabinoid signaling is essential for stress adaptation. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20439721 |
| Devane WA and Axelrod J | Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8022836 |
| Mukhopadhyay B et al. | Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21383171 |
| Izzo AA and Deutsch DG | Unique pathway for anandamide synthesis and liver regeneration. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21490298 |
| Zhang N et al. | A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15764707 |
| Cravatt BF et al. | Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11470906 |
| Paria BC et al. | The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7568154 |
| Berger A et al. | Anandamide and diet: inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11353819 |
| Mechoulam R and Deutsch DG | Toward an anandamide transporter. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16314567 |
| Liu J et al. | Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24191036 |
| Wenzel D et al. | Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24167249 |
| Gobbi G et al. | Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16352709 |
| Long JZ et al. | Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19918051 |
| Fernández-Solari J et al. | Alcohol inhibits luteinizing hormone-releasing hormone release by activating the endocannabinoid system. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:14981261 |
| Schmid PC et al. | Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9108127 |
| Glaser ST et al. | Evidence against the presence of an anandamide transporter. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12655057 |
| Kaczocha M et al. | Identification of intracellular carriers for the endocannabinoid anandamide. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19307565 |
| Collin C et al. | Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7479747 |
| Dinh TP et al. | Brain monoglyceride lipase participating in endocannabinoid inactivation. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12136125 |
| Klein TW et al. | The cannabinoid system and cytokine network. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:10998193 |
| Calignano A et al. | A role for the endogenous cannabinoid system in the peripheral control of pain initiation. | 2000 | Prog. Brain Res. | pmid:11098711 |
| Iannotti FA et al. | Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders. | 2016 | Prog. Lipid Res. | pmid:26965148 |
| Brown I et al. | Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators. | 2013 | Prog. Lipid Res. | pmid:23103355 |
| Ueda N et al. | N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA). | 2010 | Prog. Lipid Res. | pmid:20152858 |
| Umathe SN et al. | Endocannabinoids mediate anxiolytic-like effect of acetaminophen via CB1 receptors. | 2009 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:19580839 |
| Gomes FV et al. | Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice. | 2011 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:21111767 |
| Bystrowska B et al. | Changes in endocannabinoid and N-acylethanolamine levels in rat brain structures following cocaine self-administration and extinction training. | 2014 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:24334211 |
| Campos AC and Guimarães FS | Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. | 2009 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:19735690 |
| Gould GG et al. | Acetaminophen differentially enhances social behavior and cortical cannabinoid levels in inbred mice. | 2012 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:22542870 |
| Mechoulam R | Discovery of endocannabinoids and some random thoughts on their possible roles in neuroprotection and aggression. | 2002 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12052029 |
| Sugiura T et al. | Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. | 2002 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12052034 |
| Fontana A et al. | Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8577784 |