Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Ferrer B et al. Regulation of brain anandamide by acute administration of ethanol. 2007 Biochem. J. pmid:17302558
Wisnoskey BJ et al. Activation of vanilloid receptor type I in the endoplasmic reticulum fails to activate store-operated Ca2+ entry. 2003 Biochem. J. pmid:12608892
Gómez del Pulgar T et al. The CB1 cannabinoid receptor is coupled to the activation of protein kinase B/Akt. 2000 Biochem. J. pmid:10749665
Sun YX et al. Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D. 2004 Biochem. J. pmid:14998370
Bisogno T et al. Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. 1997 Biochem. J. pmid:9065792
Di Marzo V et al. Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells. 2001 Biochem. J. pmid:11485574
Correa F et al. Anandamide inhibits IL-12p40 production by acting on the promoter repressor element GA-12: possible involvement of the COX-2 metabolite prostamide E(2). 2008 Biochem. J. pmid:17961121
Bornheim LM et al. Microsomal cytochrome P450-mediated liver and brain anandamide metabolism. 1995 Biochem. Pharmacol. pmid:7669071
Childers SR et al. Effects of anandamide on cannabinoid receptors in rat brain membranes. 1994 Biochem. Pharmacol. pmid:8129747
Fowler CJ et al. Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid. 2003 Biochem. Pharmacol. pmid:12948856
Hansen HS and Diep TA N-acylethanolamines, anandamide and food intake. 2009 Biochem. Pharmacol. pmid:19413995
Ortar G et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. 2003 Biochem. Pharmacol. pmid:12732359
Mechoulam R et al. Search for endogenous ligands of the cannabinoid receptor. 1994 Biochem. Pharmacol. pmid:7980618
Goparaju SK et al. Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors. 1999 Biochem. Pharmacol. pmid:9933030
Burstein SH et al. Regulation of anandamide tissue levels by N-arachidonylglycine. 2002 Biochem. Pharmacol. pmid:12234618
Guzmán M et al. Effects of anandamide on hepatic fatty acid metabolism. 1995 Biochem. Pharmacol. pmid:7575652
Burstein SH and Hunter SA Stimulation of anandamide biosynthesis in N-18TG2 neuroblastoma cells by delta 9-tetrahydrocannabinol (THC). 1995 Biochem. Pharmacol. pmid:7702643
Deutsch DG and Chin SA Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. 1993 Biochem. Pharmacol. pmid:8373432
Lo YK et al. Effect of arvanil (N-arachidonoyl-vanillyl-amine), a nonpungent anandamide-capsaicin hybrid, on ion currents in NG108-15 neuronal cells. 2003 Biochem. Pharmacol. pmid:12566085
Lanzafame AA et al. Effects of anandamide on the binding and signaling properties of M1 muscarinic acetylcholine receptors. 2004 Biochem. Pharmacol. pmid:15498511