Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Spinal Cord Injuries D013119 34 associated lipids
Sleep Deprivation D012892 5 associated lipids
Shock, Septic D012772 11 associated lipids
Seizures D012640 87 associated lipids
Schistosomiasis japonica D012554 3 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Pregnancy, Ectopic D011271 5 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Peptic Ulcer D010437 19 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Levin M and Mercola M Gap junctions are involved in the early generation of left-right asymmetry. 1998 Dev. Biol. pmid:9806775
Aceto MD et al. Anandamide, an endogenous cannabinoid, has a very low physical dependence potential. 1998 J. Pharmacol. Exp. Ther. pmid:9808686
Patel NA et al. Arachidonylethanolamide (AEA) activation of FOS proto-oncogene protein immunoreactivity in the rat brain. 1998 Brain Res. pmid:9666136
Calignano A et al. Control of pain initiation by endogenous cannabinoids. 1998 Nature pmid:9685157
Stefano GB et al. Macrophage behavior associated with acute and chronic exposure to HIV GP120, morphine and anandamide: endothelial implications. 1998 Int. J. Cardiol. pmid:9687087
Stefano GB Autoimmunovascular regulation: morphine and anandamide and ancondamide stimulated nitric oxide release. 1998 J. Neuroimmunol. pmid:9610675
Smith FL et al. Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats. 1998 Pharmacol. Biochem. Behav. pmid:9610941
Gurwitz D and Kloog Y Do endogenous cannabinoids contribute to HIV-mediated immune failure? 1998 Mol Med Today pmid:9612798
Qin C et al. Determination of anandamide amidase activity using ultraviolet-active amine derivatives and reverse-phase high-performance liquid chromatography. 1998 Anal. Biochem. pmid:9683506
Chakrabarti A et al. Neurobehavioral effects of anandamide and cannabinoid receptor gene expression in mice. 1998 Brain Res. Bull. pmid:9434204
van Zadelhoff G et al. With anandamide as substrate plant 5-lipoxygenases behave like 11-lipoxygenases. 1998 Biochem. Biophys. Res. Commun. pmid:9675081
Richardson JD et al. Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. 1998 Pain pmid:9539680
Brăiloiu C et al. [Endothelium-derived hyperpolarizing factor]. 1998 Jul-Dec Rev Med Chir Soc Med Nat Iasi pmid:10756843
Childers SR and Breivogel CS Cannabis and endogenous cannabinoid systems. 1998 Jun-Jul Drug Alcohol Depend pmid:9716939
Sugiura T et al. Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds. 1999 J. Biol. Chem. pmid:9915812
Beltramo M and Piomelli D Anandamide transport inhibition by the vanilloid agonist olvanil. 1999 Eur. J. Pharmacol. pmid:9920187
Chaytor AT et al. The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication. 1999 J. Physiol. (Lond.) pmid:10523421
Piomelli D et al. Structural determinants for recognition and translocation by the anandamide transporter. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10318965
Mombouli JV et al. Anandamide-induced mobilization of cytosolic Ca2+ in endothelial cells. 1999 Br. J. Pharmacol. pmid:10323591
Watanabe K et al. Pharmacological effects in mice of anandamide and its related fatty acid ethanolamides, and enhancement of cataleptogenic effect of anandamide by phenylmethylsulfonyl fluoride. 1999 Biol. Pharm. Bull. pmid:10328555
Mechoulam R and Ben-Shabat S From gan-zi-gun-nu to anandamide and 2-arachidonoylglycerol: the ongoing story of cannabis. 1999 Nat Prod Rep pmid:10331283
Burstein SH The cannabinoid acids: nonpsychoactive derivatives with therapeutic potential. 1999 Pharmacol. Ther. pmid:10341359
Di Marzo V et al. Metabolism of anandamide and 2-arachidonoylglycerol: an historical overview and some recent developments. 1999 Lipids pmid:10419192
Hansen HS et al. Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity. 1999 Lipids pmid:10419193
Kiss Z Anandamide stimulates phospholipase D activity in PC12 cells but not in NIH 3T3 fibroblasts. 1999 FEBS Lett. pmid:10214947
Maccarrone M et al. Anandamide activates human platelets through a pathway independent of the arachidonate cascade. 1999 FEBS Lett. pmid:10214961
Yang HY et al. GC/MS analysis of anandamide and quantification of N-arachidonoylphosphatidylethanolamides in various brain regions, spinal cord, testis, and spleen of the rat. 1999 J. Neurochem. pmid:10217273
Raffa RB et al. Differential cholera-toxin sensitivity of supraspinal antinociception induced by the cannabinoid agonists delta9-THC, WIN 55,212-2 and anandamide in mice. 1999 Neurosci. Lett. pmid:10218903
De Petrocellis L et al. Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response. 1999 Neuroscience pmid:10392859
Williams CM and Kirkham TC Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors. 1999 Psychopharmacology (Berl.) pmid:10353436
Járai Z et al. Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10570211
Sagan S et al. Anandamide and WIN 55212-2 inhibit cyclic AMP formation through G-protein-coupled receptors distinct from CB1 cannabinoid receptors in cultured astrocytes. 1999 Eur. J. Neurosci. pmid:10051770
Kobayashi H et al. Recent progress in the neurotoxicology of natural drugs associated with dependence or addiction, their endogenous agonists and receptors. 1999 J Toxicol Sci pmid:10073332
Bisogno T et al. Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function. 1999 Biochem. Biophys. Res. Commun. pmid:10079192
Fleming I et al. Inhibition of the production of endothelium-derived hyperpolarizing factor by cannabinoid receptor agonists. 1999 Br. J. Pharmacol. pmid:10193775
Hohmann AG et al. Pre- and postsynaptic distribution of cannabinoid and mu opioid receptors in rat spinal cord. 1999 Brain Res. pmid:10082879
Wang J et al. Stage-specific excitation of cannabinoid receptor exhibits differential effects on mouse embryonic development. 1999 Biol. Reprod. pmid:10084956
Martin BR et al. Discovery and characterization of endogenous cannabinoids. 1999 Life Sci. pmid:10462059
Khanolkar AD and Makriyannis A Structure-activity relationships of anandamide, an endogenous cannabinoid ligand. 1999 Life Sci. pmid:10462061
Howlett AC et al. Signal transduction of eicosanoid CB1 receptor ligands. 1999 Life Sci. pmid:10462062
Di Marzo V Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators. 1999 Life Sci. pmid:10462065
Ueda N et al. An acid amidase hydrolyzing anandamide as an endogenous ligand for cannabinoid receptors. 1999 FEBS Lett. pmid:10431820
Fowler CJ et al. Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen. 1999 Arch. Biochem. Biophys. pmid:9989926
Basavarajappa BS and Hungund BL Chronic ethanol increases the cannabinoid receptor agonist anandamide and its precursor N-arachidonoylphosphatidylethanolamine in SK-N-SH cells. 1999 J. Neurochem. pmid:9930723
Wagner JA et al. Mesenteric vasodilation mediated by endothelial anandamide receptors. 1999 Hypertension pmid:9931142
Goparaju SK et al. Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors. 1999 Biochem. Pharmacol. pmid:9933030
Castellano C et al. Strain-dependent effects of anandamide on memory consolidation in mice are antagonized by naltrexone. 1999 Behav Pharmacol pmid:10780251
Gebremedhin D et al. Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current. 1999 Am. J. Physiol. pmid:10362691
Melck D et al. Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors. 1999 Biochem. Biophys. Res. Commun. pmid:10448105
Bisogno T et al. Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina. 1999 Arch. Biochem. Biophys. pmid:10577359