Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Hyperinsulinism D006946 27 associated lipids
Endotoxemia D019446 27 associated lipids
Neuralgia D009437 28 associated lipids
Obesity D009765 29 associated lipids
Catalepsy D002375 30 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Memory Disorders D008569 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Epilepsy D004827 35 associated lipids
Fever D005334 35 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Hypotension D007022 41 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Hyperalgesia D006930 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Andrianova EL et al. In vitro effects of anandamide and prostamide e2 on normal and transformed nerve cells. 2011 Bull. Exp. Biol. Med. pmid:22442796
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Busquets-Garcia A et al. Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses. 2011 Biol. Psychiatry pmid:21684528
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Munguba H et al. Pre-training anandamide infusion within the basolateral amygdala impairs plus-maze discriminative avoidance task in rats. 2011 Neurobiol Learn Mem pmid:21440651
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Kawahara H et al. Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. 2011 Br. J. Pharmacol. pmid:21175570
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Zaccagnino P et al. Anandamide inhibits oxidative phosphorylation in isolated liver mitochondria. 2011 FEBS Lett. pmid:21187088
Di Marzo V Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight. 2011 Nat. Neurosci. pmid:21187849
Bari M et al. The manifold actions of endocannabinoids on female and male reproductive events. 2011 Front Biosci (Landmark Ed) pmid:21196184
Guindon J et al. Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. 2011 Br. J. Pharmacol. pmid:21198549
Liao YS et al. [Anandamide inhibits the growth of colorectal cancer cells through CB1 and lipid rafts]. 2011 Zhonghua Zhong Liu Za Zhi pmid:21575494
Shekhar C Mixed signals: cannabinoid system offers new therapeutic possibilities as well as challenges. 2011 Chem. Biol. pmid:21609833
Umathe SN et al. Involvement of endocannabinoids in antidepressant and anti-compulsive effect of fluoxetine in mice. 2011 Behav. Brain Res. pmid:21549765
Arias-Carrión O et al. Biochemical modulation of the sleep-wake cycle: endogenous sleep-inducing factors. 2011 J. Neurosci. Res. pmid:21557294
Sordelli MS et al. The effect of anandamide on uterine nitric oxide synthase activity depends on the presence of the blastocyst. 2011 PLoS ONE pmid:21559512
Engel MA et al. Inhibitory CB1 and activating/desensitizing TRPV1-mediated cannabinoid actions on CGRP release in rodent skin. 2011 Neuropeptides pmid:21514666
Hutchins HL et al. Eicosapentaenoic acid decreases expression of anandamide synthesis enzyme and cannabinoid receptor 2 in osteoblast-like cells. 2011 J. Nutr. Biochem. pmid:20951563
Gervasi MG et al. Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation. 2011 PLoS ONE pmid:21347292
Quercioli A et al. Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity. 2011 Eur. Heart J. pmid:21303779
Correa F et al. The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells. 2011 Brain Behav. Immun. pmid:21310228
Kopczyńska B et al. Anandamide enhances expression of heat shock proteins Hsp70 and Hsp25 in rat lungs. 2011 Eur. J. Pharmacol. pmid:21756900
Yoshino H et al. Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex. 2011 J. Physiol. (Lond.) pmid:21807615
Theile JW and Cummins TR Inhibition of Navβ4 peptide-mediated resurgent sodium currents in Nav1.7 channels by carbamazepine, riluzole, and anandamide. 2011 Mol. Pharmacol. pmid:21788423
Ndong C et al. Cloning and pharmacological characterization of the dog cannabinoid CBâ‚‚receptor. 2011 Eur. J. Pharmacol. pmid:21871882
Altinsoy A et al. A cannabinoid ligand, anandamide, exacerbates endotoxin-induced uveitis in rabbits. 2011 J Ocul Pharmacol Ther pmid:21848425
Mestre L et al. Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB(1) receptors. 2011 J Neuroinflammation pmid:21851608
Feledziak M et al. SAR and LC/MS studies of β-lactamic inhibitors of human fatty acid amide hydrolase (hFAAH): evidence of a nonhydrolytic process. 2011 J. Med. Chem. pmid:21899370
Palermo G et al. Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas. 2011 J. Med. Chem. pmid:21830831
Khasabova IA et al. Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain. 2011 Pharmacol. Res. pmid:21440630
Zoerner AA et al. Allergen challenge increases anandamide in bronchoalveolar fluid of patients with allergic asthma. 2011 Clin. Pharmacol. Ther. pmid:21716266
Brailoiu GC et al. Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide. 2011 J. Biol. Chem. pmid:21719698
Catanzaro G et al. Effect of capacitation on the endocannabinoid system of mouse sperm. 2011 Mol. Cell. Endocrinol. pmid:21723369