Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Endotoxemia D019446 27 associated lipids
Hyperinsulinism D006946 27 associated lipids
Neuralgia D009437 28 associated lipids
Obesity D009765 29 associated lipids
Catalepsy D002375 30 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Memory Disorders D008569 33 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Fever D005334 35 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Epilepsy D004827 35 associated lipids
Nervous System Diseases D009422 37 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Hypotension D007022 41 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
pmid:26374993
pmid:25601395
pmid:28583049
pmid:
Barinaga M Pot, heroin unlock new areas for neuroscience. 1992 Science pmid:1335165
Devane WA et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. 1992 Science pmid:1470919
Bornheim LM et al. The effect of cannabidiol on mouse hepatic microsomal cytochrome P450-dependent anandamide metabolism. 1993 Biochem. Biophys. Res. Commun. pmid:8267610
Wickens AP and Pertwee RG delta 9-Tetrahydrocannabinol and anandamide enhance the ability of muscimol to induce catalepsy in the globus pallidus of rats. 1993 Eur. J. Pharmacol. pmid:8119321
Pertwee RG et al. Cross-tolerance between delta-9-tetrahydrocannabinol and the cannabimimetic agents, CP 55,940, WIN 55,212-2 and anandamide. 1993 Br. J. Pharmacol. pmid:8306090
Mackie K et al. Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells. 1993 Mol. Pharmacol. pmid:8371711
Felder CC et al. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:8395053
Iversen LL Pharmacology. Medical uses of marijuana? 1993 Nature pmid:8395659
Johnson DE et al. Isolation, identification and synthesis of an endogenous arachidonic amide that inhibits calcium channel antagonist 1,4-dihydropyridine binding. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8341720
Hanus L et al. Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. 1993 J. Med. Chem. pmid:8411021
Fride E and Mechoulam R Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent. 1993 Eur. J. Pharmacol. pmid:8384116
Munro S et al. Molecular characterization of a peripheral receptor for cannabinoids. 1993 Nature pmid:7689702
Vogel Z et al. Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase. 1993 J. Neurochem. pmid:8515284
Crawley JN et al. Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents. 1993 Pharmacol. Biochem. Behav. pmid:7906042
Deutsch DG and Chin SA Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. 1993 Biochem. Pharmacol. pmid:8373432
Weidenfeld J et al. Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat. 1994 Neuroendocrinology pmid:8127398
Childers SR et al. Effects of anandamide on cannabinoid receptors in rat brain membranes. 1994 Biochem. Pharmacol. pmid:8129747
Devane WA New dawn of cannabinoid pharmacology. 1994 Trends Pharmacol. Sci. pmid:8165721
Iversen L Pharmacology. Endogenous cannabinoids. 1994 Nature pmid:7990950
Van der Kloot W Anandamide, a naturally-occurring agonist of the cannabinoid receptor, blocks adenylate cyclase at the frog neuromuscular junction. 1994 Brain Res. pmid:7953630
Schwarz H et al. Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis. 1994 J. Neuroimmunol. pmid:7962480
Di Marzo V et al. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. 1994 Nature pmid:7990962
Schuel H et al. Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8052642
Smith PB et al. The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice. 1994 J. Pharmacol. Exp. Ther. pmid:8035318
Mechoulam R et al. Search for endogenous ligands of the cannabinoid receptor. 1994 Biochem. Pharmacol. pmid:7980618
Koutek B et al. Inhibitors of arachidonoyl ethanolamide hydrolysis. 1994 J. Biol. Chem. pmid:8083191
Kruszka KK and Gross RW The ATP- and CoA-independent synthesis of arachidonoylethanolamide. A novel mechanism underlying the synthesis of the endogenous ligand of the cannabinoid receptor. 1994 J. Biol. Chem. pmid:8182035
Devane WA and Axelrod J Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8022836
Fride E et al. Low doses of anandamides inhibit pharmacological effects of delta 9-tetrahydrocannabinol. 1995 J. Pharmacol. Exp. Ther. pmid:7853184
Adams IB et al. Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs. 1995 J. Pharmacol. Exp. Ther. pmid:7791088
Welch SP et al. Characterization of anandamide- and fluoroanandamide-induced antinociception and cross-tolerance to delta 9-THC after intrathecal administration to mice: blockade of delta 9-THC-induced antinociception. 1995 J. Pharmacol. Exp. Ther. pmid:7791096
Musty RE et al. A review of recent advances in cannabinoid research and the 1994 International Symposium on Cannabis and the Cannabinoids. 1995 Life Sci. pmid:7776816
Omeir RL et al. Arachidonoyl ethanolamide-[1,2-14C] as a substrate for anandamide amidase. 1995 Life Sci. pmid:7776824
Romero J et al. The endogenous cannabinoid receptor ligand, anandamide, inhibits the motor behavior: role of nigrostriatal dopaminergic neurons. 1995 Life Sci. pmid:7776829
Adams IB et al. Pharmacological and behavioral evaluation of alkylated anandamide analogs. 1995 Life Sci. pmid:7776830
Wenger T et al. Effects of anandamide (endogen cannabinoid) on anterior pituitary hormone secretion in adult ovariectomized rats. 1995 Life Sci. pmid:7776832
Cabral GA et al. Anandamide inhibits macrophage-mediated killing of tumor necrosis factor-sensitive cells. 1995 Life Sci. pmid:7776833
Wiley J et al. Discriminative stimulus effects of anandamide in rats. 1995 Eur. J. Pharmacol. pmid:7781695
Facci L et al. Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7724569
Fride E Anandamides: tolerance and cross-tolerance to delta 9-tetrahydrocannabinol. 1995 Brain Res. pmid:8593598
Fontana A et al. Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:8577784
Barg J et al. Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides. 1995 Eur. J. Pharmacol. pmid:8749028
Terranova JP et al. Inhibition of long-term potentiation in rat hippocampal slices by anandamide and WIN55212-2: reversal by SR141716 A, a selective antagonist of CB1 cannabinoid receptors. 1995 Naunyn Schmiedebergs Arch. Pharmacol. pmid:8751088
Vela G et al. Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine. 1995 Neuropharmacology pmid:7566503
Paria BC et al. The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7568154
Romero J et al. Time-course of the effects of anandamide, the putative endogenous cannabinoid receptor ligand, on extrapyramidal function. 1995 Brain Res. pmid:8974649