Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Alveolar Bone Loss D016301 10 associated lipids
Learning Disorders D007859 11 associated lipids
Hyperkinesis D006948 11 associated lipids
Hyperinsulinism D006946 27 associated lipids
Muscle Spasticity D009128 5 associated lipids
Hypothermia D007035 19 associated lipids
Celiac Disease D002446 16 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Hypertension, Portal D006975 12 associated lipids
Insulin Resistance D007333 99 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Brain Concussion D001924 5 associated lipids
Endotoxemia D019446 27 associated lipids
Anorexia D000855 8 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Memory Disorders D008569 33 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Overweight D050177 11 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Bruijnzeel AW et al. Behavioral Characterization of the Effects of Cannabis Smoke and Anandamide in Rats. 2016 PLoS ONE pmid:27065006
Gouveia-Figueira S et al. Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor. 2015 PLoS ONE pmid:26406890
Thörn Pérez C et al. Substance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels. 2015 PLoS ONE pmid:26197458
Chon SH et al. Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity. 2012 PLoS ONE pmid:22937137
De Angelis V et al. Endocannabinoids control platelet activation and limit aggregate formation under flow. 2014 PLoS ONE pmid:25264625
Özdemir B et al. Endocannabinoids and inflammatory response in periodontal ligament cells. 2014 PLoS ONE pmid:25226300
Björklund E et al. Involvement of fatty acid amide hydrolase and fatty acid binding protein 5 in the uptake of anandamide by cell lines with different levels of fatty acid amide hydrolase expression: a pharmacological study. 2014 PLoS ONE pmid:25078278
Di Pasquale E et al. The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependent. 2009 PLoS ONE pmid:19330032
Gervasi MG et al. Anandamide levels fluctuate in the bovine oviduct during the oestrous cycle. 2013 PLoS ONE pmid:23977311
Leo LM et al. Age-dependent relevance of endogenous 5-lipoxygenase derivatives in anxiety-like behavior in mice. 2014 PLoS ONE pmid:24416334
Compagnucci C et al. Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells. 2013 PLoS ONE pmid:23372698
Chadwick W et al. Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. 2010 PLoS ONE pmid:21179406
Pava MJ et al. Endocannabinoid modulation of cortical up-states and NREM sleep. 2014 PLoS ONE pmid:24520411
Kwolek G et al. [Influence of anandamide, the endogenous agonist of cannabinoid receptors on the circulatory system]. 2005 Postepy Hig Med Dosw (Online) pmid:15928605
Pertwee RG Elevating endocannabinoid levels: pharmacological strategies and potential therapeutic applications. 2014 Proc Nutr Soc pmid:24135210
Burston JJ and Woodhams SG Endocannabinoid system and pain: an introduction. 2014 Proc Nutr Soc pmid:24148358
Fegley D et al. Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15138300
Berger A et al. Anandamide and diet: inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11353819
Liu J et al. Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:24191036
Gobbi G et al. Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:16352709