| MeSH term | MeSH ID | Detail |
|---|---|---|
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Osteoarthritis, Knee | D020370 | 13 associated lipids |
| Multiple Sclerosis | D009103 | 13 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Infarction, Middle Cerebral Artery | D020244 | 35 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fowler CJ et al. | Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen. | 1999 | Arch. Biochem. Biophys. | pmid:9989926 |
| Piomelli D et al. | Endogenous cannabinoid signaling. | 1998 | Neurobiol. Dis. | pmid:9974178 |
| Di Marzo V and Deutsch DG | Biochemistry of the endogenous ligands of cannabinoid receptors. | 1998 | Neurobiol. Dis. | pmid:9974173 |
| Navarro M and RodrÃguez de Fonseca F | The neurobiology of cannabinoid transmission: from anandamide signaling to higher cerebral functions and disease. | 1998 | Neurobiol. Dis. | pmid:9974172 |
| Lu R et al. | Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C. | 1999 | Am. J. Physiol. | pmid:9950961 |
| Goparaju SK et al. | Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors. | 1999 | Biochem. Pharmacol. | pmid:9933030 |
| Wagner JA et al. | Mesenteric vasodilation mediated by endothelial anandamide receptors. | 1999 | Hypertension | pmid:9931142 |
| Basavarajappa BS and Hungund BL | Chronic ethanol increases the cannabinoid receptor agonist anandamide and its precursor N-arachidonoylphosphatidylethanolamine in SK-N-SH cells. | 1999 | J. Neurochem. | pmid:9930723 |
| Beltramo M and Piomelli D | Anandamide transport inhibition by the vanilloid agonist olvanil. | 1999 | Eur. J. Pharmacol. | pmid:9920187 |
| Sugiura T et al. | Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds. | 1999 | J. Biol. Chem. | pmid:9915812 |
| Lin S et al. | Novel analogues of arachidonylethanolamide (anandamide): affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability. | 1998 | J. Med. Chem. | pmid:9876105 |
| Ueda N et al. | A hydrolase enzyme inactivating endogenous ligands for cannabinoid receptors. | 1998 | J. Med. Invest. | pmid:9864962 |
| Bonhaus DW et al. | Dual activation and inhibition of adenylyl cyclase by cannabinoid receptor agonists: evidence for agonist-specific trafficking of intracellular responses. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9864268 |
| Stahl SM | Getting stoned without inhaling: anandamide is the brain's natural marijuana. | 1998 | J Clin Psychiatry | pmid:9862600 |
| Mallet PE and Beninger RJ | The cannabinoid CB1 receptor antagonist SR141716A attenuates the memory impairment produced by delta9-tetrahydrocannabinol or anandamide. | 1998 | Psychopharmacology (Berl.) | pmid:9862397 |
| Pate DW et al. | Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits. | 1998 | Life Sci. | pmid:9851310 |
| Castellano C et al. | The effects of anandamide on memory consolidation in mice involve both D1 and D2 dopamine receptors. | 1997 | Behav Pharmacol | pmid:9832956 |
| Mechoulam R et al. | Endocannabinoids. | 1998 | Eur. J. Pharmacol. | pmid:9831287 |
| Maccarrone M et al. | Anandamide hydrolysis by human cells in culture and brain. | 1998 | J. Biol. Chem. | pmid:9822713 |
| Barnett-Norris J et al. | Exploration of biologically relevant conformations of anandamide, 2-arachidonylglycerol, and their analogues using conformational memories. | 1998 | J. Med. Chem. | pmid:9822555 |
| Murillo-RodrÃguez E et al. | Anandamide modulates sleep and memory in rats. | 1998 | Brain Res. | pmid:9813364 |
| Aceto MD et al. | Anandamide, an endogenous cannabinoid, has a very low physical dependence potential. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808686 |
| Levin M and Mercola M | Gap junctions are involved in the early generation of left-right asymmetry. | 1998 | Dev. Biol. | pmid:9806775 |
| White R and Hiley CR | The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery. | 1998 | Br. J. Pharmacol. | pmid:9806337 |
| Stein EA et al. | Selective effects of the endogenous cannabinoid arachidonylethanolamide (anandamide) on regional cerebral blood flow in the rat. | 1998 | Neuropsychopharmacology | pmid:9803424 |
| Di Marzo V et al. | Interactions between synthetic vanilloids and the endogenous cannabinoid system. | 1998 | FEBS Lett. | pmid:9801167 |
| Lichtman AH et al. | Effects of SR 141716A after acute or chronic cannabinoid administration in dogs. | 1998 | Eur. J. Pharmacol. | pmid:9797029 |
| Pestonjamasp VK and Burstein SH | Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system. | 1998 | Biochim. Biophys. Acta | pmid:9795237 |
| Tong W et al. | Derivation of a pharmacophore model for anandamide using constrained conformational searching and comparative molecular field analysis. | 1998 | J. Med. Chem. | pmid:9784095 |
| Jaggar SI et al. | The endogenous cannabinoid anandamide, but not the CB2 ligand palmitoylethanolamide, prevents the viscero-visceral hyper-reflexia associated with inflammation of the rat urinary bladder. | 1998 | Neurosci. Lett. | pmid:9774165 |
| Wiley JL et al. | Evaluation of cannabimimetic effects of structural analogs of anandamide in rats. | 1998 | Eur. J. Pharmacol. | pmid:9760024 |
| Stengel PW et al. | Pulmonary actions of anandamide, an endogenous cannabinoid receptor agonist, in guinea pigs. | 1998 | Eur. J. Pharmacol. | pmid:9754939 |
| Schneider U et al. | Cannabinoid/anandamide system and schizophrenia: is there evidence for association? | 1998 | Pharmacopsychiatry | pmid:9754842 |
| McGregor IS et al. | A comparison of delta 9-THC and anandamide induced c-fos expression in the rat forebrain. | 1998 | Brain Res. | pmid:9748483 |
| Molina-Holgado F et al. | The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway. | 1998 | FEBS Lett. | pmid:9738948 |
| Fields HL and Meng ID | Watching the pot boil. | 1998 | Nat. Med. | pmid:9734389 |
| Welch SP et al. | Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9732392 |
| Fulton D and Quilley J | Evidence against anandamide as the hyperpolarizing factor mediating the nitric oxide-independent coronary vasodilator effect of bradykinin in the rat. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9732371 |
| Berdyshev E et al. | Effects of cannabinoid receptor ligands on LPS-induced pulmonary inflammation in mice. | 1998 | Life Sci. | pmid:9718090 |
| Childers SR and Breivogel CS | Cannabis and endogenous cannabinoid systems. | 1998 Jun-Jul | Drug Alcohol Depend | pmid:9716939 |
| Varga K et al. | Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. | 1998 | FASEB J. | pmid:9707176 |
| Bisogno T et al. | Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9703957 |
| Jaggar SI et al. | The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. | 1998 | Pain | pmid:9696473 |
| Bisogno T et al. | Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation. | 1998 | Eur. J. Biochem. | pmid:9688276 |
| Stefano GB et al. | Macrophage behavior associated with acute and chronic exposure to HIV GP120, morphine and anandamide: endothelial implications. | 1998 | Int. J. Cardiol. | pmid:9687087 |
| Calignano A et al. | Control of pain initiation by endogenous cannabinoids. | 1998 | Nature | pmid:9685157 |
| Qin C et al. | Determination of anandamide amidase activity using ultraviolet-active amine derivatives and reverse-phase high-performance liquid chromatography. | 1998 | Anal. Biochem. | pmid:9683506 |
| van Zadelhoff G et al. | With anandamide as substrate plant 5-lipoxygenases behave like 11-lipoxygenases. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9675081 |
| Patel NA et al. | Arachidonylethanolamide (AEA) activation of FOS proto-oncogene protein immunoreactivity in the rat brain. | 1998 | Brain Res. | pmid:9666136 |
| Edgemond WS et al. | Human platelets and polymorphonuclear leukocytes synthesize oxygenated derivatives of arachidonylethanolamide (anandamide): their affinities for cannabinoid receptors and pathways of inactivation. | 1998 | Mol. Pharmacol. | pmid:9658204 |
| De Petrocellis L et al. | The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9653194 |
| Mallet PE and Beninger RJ | Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. | 1998 | Life Sci. | pmid:9651110 |
| Stefano GB et al. | Long-term exposure of human blood vessels to HIV gp120, morphine, and anandamide increases endothelial adhesion of monocytes: uncoupling of nitric oxide release. | 1998 | J. Cardiovasc. Pharmacol. | pmid:9641470 |
| Stefano GB et al. | Antagonism of LPS and IFN-gamma induction of iNOS in human saphenous vein endothelium by morphine and anandamide by nitric oxide inhibition of adenylate cyclase. | 1998 | J. Cardiovasc. Pharmacol. | pmid:9641464 |
| Kondo S et al. | Accumulation of various N-acylethanolamines including N-arachidonoylethanolamine (anandamide) in cadmium chloride-administered rat testis. | 1998 | Arch. Biochem. Biophys. | pmid:9637740 |
| Schmid PC et al. | Alternative pathways of anandamide biosynthesis in rat testes. | 1998 | Chem. Phys. Lipids | pmid:9631536 |
| Stefano GB et al. | Anandamide amidase inhibition enhances anandamide-stimulated nitric oxide release in invertebrate neural tissues. | 1998 | Brain Res. | pmid:9630717 |
| Di Marzo V | 'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance. | 1998 | Biochim. Biophys. Acta | pmid:9630590 |
| Paria BC et al. | Effects of cannabinoids on preimplantation mouse embryo development and implantation are mediated by brain-type cannabinoid receptors. | 1998 | Biol. Reprod. | pmid:9623610 |
| Randall MD and Kendall DA | Anandamide and endothelium-derived hyperpolarizing factor act via a common vasorelaxant mechanism in rat mesentery. | 1998 | Eur. J. Pharmacol. | pmid:9617751 |
| Gurwitz D and Kloog Y | Do endogenous cannabinoids contribute to HIV-mediated immune failure? | 1998 | Mol Med Today | pmid:9612798 |
| Smith FL et al. | Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats. | 1998 | Pharmacol. Biochem. Behav. | pmid:9610941 |
| Stefano GB | Autoimmunovascular regulation: morphine and anandamide and ancondamide stimulated nitric oxide release. | 1998 | J. Neuroimmunol. | pmid:9610675 |
| Richardson JD et al. | Antihyperalgesic effects of spinal cannabinoids. | 1998 | Eur. J. Pharmacol. | pmid:9600630 |
| Prevot V et al. | Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: neurovascular regulation. | 1998 | Brain Res. | pmid:9593913 |
| Axelrod J and Felder CC | Cannabinoid receptors and their endogenous agonist, anandamide. | 1998 | Neurochem. Res. | pmid:9566594 |
| Derocq JM et al. | The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor-independent pathway in hematopoietic cell lines. | 1998 | FEBS Lett. | pmid:9563506 |
| Qureshi J et al. | Identification and characterization of a novel synthetic cannabinoid CP 55,940 binder in rat brain cytosol. | 1998 | Mol. Cell. Biochem. | pmid:9562238 |
| Soderstrom K et al. | Discovery of novel cannabinoid receptor ligands from diverse marine organisms. | 1997 | Adv. Exp. Med. Biol. | pmid:9561107 |
| Kimura T et al. | Anandamide, an endogenous cannabinoid receptor ligand, also interacts with 5-hydroxytryptamine (5-HT) receptor. | 1998 | Biol. Pharm. Bull. | pmid:9556149 |
| Randall MD and Kendall DA | Endocannabinoids: a new class of vasoactive substances. | 1998 | Trends Pharmacol. Sci. | pmid:9550942 |
| Salzet M et al. | Leech immunocytes contain proopiomelanocortin: nitric oxide mediates hemolymph proopiomelanocortin processing. | 1997 | J. Immunol. | pmid:9548480 |
| Richardson JD et al. | Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. | 1998 | Pain | pmid:9539680 |
| Calignano A et al. | Inhibition of intestinal motility by anandamide, an endogenous cannabinoid. | 1997 | Eur. J. Pharmacol. | pmid:9537804 |
| Di Marzo V et al. | The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide. | 1998 | Biochem. J. | pmid:9512456 |
| Van der Kloot W et al. | Calcitonin gene-related peptide acts presynaptically to increase quantal size and output at frog neuromuscular junctions. | 1998 | J. Physiol. (Lond.) | pmid:9508830 |
| Giuffrida A and Piomelli D | Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma. | 1998 | FEBS Lett. | pmid:9498819 |
| Adams IB et al. | Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9495885 |
| Sulcova E et al. | Biphasic effects of anandamide. | 1998 | Pharmacol. Biochem. Behav. | pmid:9476980 |
| Goparaju SK et al. | Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand. | 1998 | FEBS Lett. | pmid:9475172 |
| Pratt PF et al. | N-arachidonylethanolamide relaxation of bovine coronary artery is not mediated by CB1 cannabinoid receptor. | 1998 | Am. J. Physiol. | pmid:9458889 |
| Hillard CJ and Campbell WB | Biochemistry and pharmacology of arachidonylethanolamide, a putative endogenous cannabinoid. | 1997 | J. Lipid Res. | pmid:9458263 |
| Hampson AJ et al. | Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission. | 1998 | J. Neurochem. | pmid:9453561 |
| Pate DW et al. | Effects of topical alpha-substituted anandamides on intraocular pressure in normotensive rabbits. | 1997 | Pharm. Res. | pmid:9453062 |
| Thomas EA et al. | Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system. | 1997 | J. Neurosci. Res. | pmid:9452020 |
| Chakrabarti A et al. | Neurobehavioral effects of anandamide and cannabinoid receptor gene expression in mice. | 1998 | Brain Res. Bull. | pmid:9434204 |
| Jarrahian A and Hillard CJ | Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9431821 |
| Zygmunt PM et al. | Studies on the effects of anandamide in rat hepatic artery. | 1997 | Br. J. Pharmacol. | pmid:9422814 |
| White R and Hiley CR | A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. | 1997 | Br. J. Pharmacol. | pmid:9422801 |
| Wiley JL et al. | Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. | 1997 | Pharmacol. Biochem. Behav. | pmid:9408225 |
| Compton DR and Martin BR | The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9399986 |
| Wagner JA et al. | Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. | 1997 | Nature | pmid:9394002 |
| Calignano A et al. | Potentiation of anandamide hypotension by the transport inhibitor, AM404. | 1997 | Eur. J. Pharmacol. | pmid:9389389 |
| Burkey TH et al. | Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain. | 1997 | Eur. J. Pharmacol. | pmid:9384246 |
| Randall MD and Kendall DA | Involvement of a cannabinoid in endothelium-derived hyperpolarizing factor-mediated coronary vasorelaxation. | 1997 | Eur. J. Pharmacol. | pmid:9369375 |
| Sasaki T and Chang MC | N-arachidonylethanolamine (anandamide) formation from N-arachidonylphosphatidylethanolamine in rat brain membranes. | 1997 | Life Sci. | pmid:9365227 |
| van der Stelt M et al. | The effect of hydroxylation of linoleoyl amides on their cannabinomimetic properties. | 1997 | FEBS Lett. | pmid:9357990 |
| Seltzman HH et al. | Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide. | 1997 | J. Med. Chem. | pmid:9357529 |
| Ryan WJ et al. | Potent anandamide analogs: the effect of changing the length and branching of the end pentyl chain. | 1997 | J. Med. Chem. | pmid:9357528 |
| Stark S et al. | Binding of aminoalkylindoles to noncannabinoid binding sites in NG108-15 cells. | 1997 | Cell. Mol. Neurobiol. | pmid:9353590 |