Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Liver Cirrhosis D008103 67 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Nervous System Diseases D009422 37 associated lipids
Ataxia D001259 20 associated lipids
Brain Edema D001929 20 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Schneider U et al. Cannabinoid/anandamide system and schizophrenia: is there evidence for association? 1998 Pharmacopsychiatry pmid:9754842
Stengel PW et al. Pulmonary actions of anandamide, an endogenous cannabinoid receptor agonist, in guinea pigs. 1998 Eur. J. Pharmacol. pmid:9754939
Pestonjamasp VK and Burstein SH Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system. 1998 Biochim. Biophys. Acta pmid:9795237
White R and Hiley CR The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery. 1998 Br. J. Pharmacol. pmid:9806337
Bisogno T et al. Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation. 1998 Eur. J. Biochem. pmid:9688276
Levin M and Mercola M Gap junctions are involved in the early generation of left-right asymmetry. 1998 Dev. Biol. pmid:9806775
Aceto MD et al. Anandamide, an endogenous cannabinoid, has a very low physical dependence potential. 1998 J. Pharmacol. Exp. Ther. pmid:9808686
Murillo-Rodríguez E et al. Anandamide modulates sleep and memory in rats. 1998 Brain Res. pmid:9813364
Jaggar SI et al. The endogenous cannabinoid anandamide, but not the CB2 ligand palmitoylethanolamide, prevents the viscero-visceral hyper-reflexia associated with inflammation of the rat urinary bladder. 1998 Neurosci. Lett. pmid:9774165
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Welch SP et al. Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A. 1998 J. Pharmacol. Exp. Ther. pmid:9732392
Fields HL and Meng ID Watching the pot boil. 1998 Nat. Med. pmid:9734389
Pate DW et al. Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits. 1998 Life Sci. pmid:9851310
Molina-Holgado F et al. The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway. 1998 FEBS Lett. pmid:9738948
Patel NA et al. Arachidonylethanolamide (AEA) activation of FOS proto-oncogene protein immunoreactivity in the rat brain. 1998 Brain Res. pmid:9666136
Calignano A et al. Control of pain initiation by endogenous cannabinoids. 1998 Nature pmid:9685157
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Smith FL et al. Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats. 1998 Pharmacol. Biochem. Behav. pmid:9610941
Gurwitz D and Kloog Y Do endogenous cannabinoids contribute to HIV-mediated immune failure? 1998 Mol Med Today pmid:9612798
Prevot V et al. Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: neurovascular regulation. 1998 Brain Res. pmid:9593913
Di Marzo V 'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance. 1998 Biochim. Biophys. Acta pmid:9630590
Stefano GB et al. Anandamide amidase inhibition enhances anandamide-stimulated nitric oxide release in invertebrate neural tissues. 1998 Brain Res. pmid:9630717
Schmid PC et al. Alternative pathways of anandamide biosynthesis in rat testes. 1998 Chem. Phys. Lipids pmid:9631536
Varga K et al. Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. 1998 FASEB J. pmid:9707176
Mallet PE and Beninger RJ Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. 1998 Life Sci. pmid:9651110
Qin C et al. Determination of anandamide amidase activity using ultraviolet-active amine derivatives and reverse-phase high-performance liquid chromatography. 1998 Anal. Biochem. pmid:9683506
De Petrocellis L et al. The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9653194
Berdyshev E et al. Effects of cannabinoid receptor ligands on LPS-induced pulmonary inflammation in mice. 1998 Life Sci. pmid:9718090
Jaggar SI et al. The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. 1998 Pain pmid:9696473
Bisogno T et al. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. 1998 Biochem. Biophys. Res. Commun. pmid:9703957
Mallet PE and Beninger RJ The cannabinoid CB1 receptor antagonist SR141716A attenuates the memory impairment produced by delta9-tetrahydrocannabinol or anandamide. 1998 Psychopharmacology (Berl.) pmid:9862397
Derocq JM et al. The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor-independent pathway in hematopoietic cell lines. 1998 FEBS Lett. pmid:9563506
Chakrabarti A et al. Neurobehavioral effects of anandamide and cannabinoid receptor gene expression in mice. 1998 Brain Res. Bull. pmid:9434204
Lin S et al. Novel analogues of arachidonylethanolamide (anandamide): affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability. 1998 J. Med. Chem. pmid:9876105
van Zadelhoff G et al. With anandamide as substrate plant 5-lipoxygenases behave like 11-lipoxygenases. 1998 Biochem. Biophys. Res. Commun. pmid:9675081
Stein EA et al. Selective effects of the endogenous cannabinoid arachidonylethanolamide (anandamide) on regional cerebral blood flow in the rat. 1998 Neuropsychopharmacology pmid:9803424
Randall MD and Kendall DA Anandamide and endothelium-derived hyperpolarizing factor act via a common vasorelaxant mechanism in rat mesentery. 1998 Eur. J. Pharmacol. pmid:9617751
Edgemond WS et al. Human platelets and polymorphonuclear leukocytes synthesize oxygenated derivatives of arachidonylethanolamide (anandamide): their affinities for cannabinoid receptors and pathways of inactivation. 1998 Mol. Pharmacol. pmid:9658204
Giuffrida A and Piomelli D Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma. 1998 FEBS Lett. pmid:9498819
Tong W et al. Derivation of a pharmacophore model for anandamide using constrained conformational searching and comparative molecular field analysis. 1998 J. Med. Chem. pmid:9784095
Richardson JD et al. Antihyperalgesic effects of spinal cannabinoids. 1998 Eur. J. Pharmacol. pmid:9600630
Goparaju SK et al. Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand. 1998 FEBS Lett. pmid:9475172
Hampson AJ et al. Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission. 1998 J. Neurochem. pmid:9453561
Sulcova E et al. Biphasic effects of anandamide. 1998 Pharmacol. Biochem. Behav. pmid:9476980
Kimura T et al. Anandamide, an endogenous cannabinoid receptor ligand, also interacts with 5-hydroxytryptamine (5-HT) receptor. 1998 Biol. Pharm. Bull. pmid:9556149
Pratt PF et al. N-arachidonylethanolamide relaxation of bovine coronary artery is not mediated by CB1 cannabinoid receptor. 1998 Am. J. Physiol. pmid:9458889
Qureshi J et al. Identification and characterization of a novel synthetic cannabinoid CP 55,940 binder in rat brain cytosol. 1998 Mol. Cell. Biochem. pmid:9562238
Paria BC et al. Effects of cannabinoids on preimplantation mouse embryo development and implantation are mediated by brain-type cannabinoid receptors. 1998 Biol. Reprod. pmid:9623610
Richardson JD et al. Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. 1998 Pain pmid:9539680