| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dyskinesia, Drug-Induced | D004409 | 15 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Ventricular Fibrillation | D014693 | 16 associated lipids |
| Parkinson Disease, Secondary | D010302 | 17 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Pancreatitis, Acute Necrotizing | D019283 | 18 associated lipids |
| Hypothermia | D007035 | 19 associated lipids |
| Peptic Ulcer | D010437 | 19 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Millns PJ et al. | Effects of inhibition of fatty acid amide hydrolase vs. the anandamide membrane transporter on TRPV1-mediated calcium responses in adult DRG neurons; the role of CB receptors. | 2006 | Eur. J. Neurosci. | pmid:17229097 |
| Nilsson O et al. | The cannabinoid agonist WIN 55,212-2 inhibits TNF-alpha-induced neutrophil transmigration across ECV304 cells. | 2006 | Eur. J. Pharmacol. | pmid:16928371 |
| Schuel H | Tuning the oviduct to the anandamide tone. | 2006 | J. Clin. Invest. | pmid:16886056 |
| Kasai HF et al. | Studies on high-energy collision-induced dissociation of endogenous cannabinoids: 2-arachidonoylglycerol and n-arachidonoylethanolamide in FAB-mass spectrometry. | 2006 | Anal Sci | pmid:16837740 |
| Murillo-RodrÃguez E et al. | Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. | 2006 | FEBS Lett. | pmid:16844117 |
| Liu J et al. | A biosynthetic pathway for anandamide. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16938887 |
| Mechoulam R et al. | Endocannabinoids, feeding and suckling--from our perspective. | 2006 | Int J Obes (Lond) | pmid:16570101 |
| Matias I et al. | Endogenous cannabinoids in the brain and peripheral tissues: regulation of their levels and control of food intake. | 2006 | Int J Obes (Lond) | pmid:16570107 |
| Schiano Moriello A et al. | Development of the first potential covalent inhibitors of anandamide cellular uptake. | 2006 | J. Med. Chem. | pmid:16570928 |
| Kudo R and Hatake K | [Effect of ethanol on anandamide-induced sensory nerve dependent vasorelaxation]. | 2006 | Nihon Arukoru Yakubutsu Igakkai Zasshi | pmid:17313058 |
| Appendino G et al. | Oxyhomologues of anandamide and related endolipids: chemoselective synthesis and biological activity. | 2006 | J. Med. Chem. | pmid:16570929 |
| Chang L et al. | Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms. | 2006 | Br. J. Pharmacol. | pmid:16501580 |
| Fezza F et al. | Methods to assay anandamide hydrolysis and transport in synaptosomes. | 2006 | Methods Mol. Med. | pmid:16506407 |
| Kaczocha M et al. | Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase. | 2006 | J. Biol. Chem. | pmid:16461355 |
| Waku K | [Endogenous cannabinoid receptor ligands--anandamide and 2-arachidonoylglycerol]. | 2006 | Yakugaku Zasshi | pmid:16462096 |
| Petersen G et al. | Intestinal levels of anandamide and oleoylethanolamide in food-deprived rats are regulated through their precursors. | 2006 | Biochim. Biophys. Acta | pmid:16478679 |
| Guindon J et al. | Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain. | 2006 | Pain | pmid:16480822 |
| Busch L et al. | Effects of castration on cannabinoid cb receptor expression and on the biological actions of cannabinoid in the parotid gland. | 2006 | Clin. Exp. Pharmacol. Physiol. | pmid:16487271 |
| Schelling G et al. | Effects of general anesthesia on anandamide blood levels in humans. | 2006 | Anesthesiology | pmid:16436846 |
| Guindon J and Beaulieu P | Antihyperalgesic effects of local injections of anandamide, ibuprofen, rofecoxib and their combinations in a model of neuropathic pain. | 2006 | Neuropharmacology | pmid:16442133 |
| Bermúdez-Siva FJ et al. | Activation of cannabinoid CB1 receptors induces glucose intolerance in rats. | 2006 | Eur. J. Pharmacol. | pmid:16423347 |
| Overton HA et al. | Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. | 2006 | Cell Metab. | pmid:16517404 |
| Matias I et al. | Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17011761 |
| Bari M et al. | Effect of lipid rafts on Cb2 receptor signaling and 2-arachidonoyl-glycerol metabolism in human immune cells. | 2006 | J. Immunol. | pmid:17015679 |
| Tan B et al. | Targeted lipidomics: discovery of new fatty acyl amides. | 2006 | AAPS J | pmid:17025263 |
| Guindon J et al. | Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides? | 2006 | Eur. J. Pharmacol. | pmid:17027744 |
| Prestifilippo JP et al. | Inhibition of salivary secretion by activation of cannabinoid receptors. | 2006 | Exp. Biol. Med. (Maywood) | pmid:16946411 |
| Spoto B et al. | Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2-arachidonoylglycerol. | 2006 | Biochimie | pmid:16949718 |
| Vlachou S et al. | Effects of endocannabinoid neurotransmission modulators on brain stimulation reward. | 2006 | Psychopharmacology (Berl.) | pmid:16953388 |
| Mulder AM and Cravatt BF | Endocannabinoid metabolism in the absence of fatty acid amide hydrolase (FAAH): discovery of phosphorylcholine derivatives of N-acyl ethanolamines. | 2006 | Biochemistry | pmid:16981687 |
| Hong Z et al. | Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus. | 2006 | Circulation | pmid:16982938 |
| Stefano GB and Salamon EJ | Nitric oxide and anandamide in OMT research. | 2006 | J Am Osteopath Assoc | pmid:17122026 |
| Lambert RC et al. | Modulation of neuronal T-type calcium channels. | 2006 | CNS Neurol Disord Drug Targets | pmid:17168746 |
| Siegmund SV et al. | Fatty acid amide hydrolase determines anandamide-induced cell death in the liver. | 2006 | J. Biol. Chem. | pmid:16418162 |
| Salo OM et al. | 3D-QSAR studies on cannabinoid CB1 receptor agonists: G-protein activation as biological data. | 2006 | J. Med. Chem. | pmid:16420041 |
| Kohro S et al. | Anandamide absorption by direct hemoperfusion with polymixin B-immobilized fiber improves the prognosis and organ failure assessment score in patients with sepsis. | 2006 | J Anesth | pmid:16421670 |
| Rawls SM et al. | Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats. | 2006 | Pharmacol. Biochem. Behav. | pmid:16647109 |
| Parkkari T et al. | Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide. | 2006 | Bioorg. Med. Chem. | pmid:16644227 |
| McFarland MJ et al. | Detergent-resistant membrane microdomains in the disposition of the lipid signaling molecule anandamide. | 2006 | AAPS J | pmid:16584138 |
| Giuliano M et al. | Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway. | 2006 | Int. J. Mol. Med. | pmid:16596265 |
| Di Marzo M et al. | Synthesis, conformational analysis and CB1 binding affinity of hairpin-like anandamide pseudopeptide mimetics. | 2006 | J. Pept. Sci. | pmid:16534762 |
| Cobellis G et al. | Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells. | 2006 | Biol. Reprod. | pmid:16611862 |
| Solinas M et al. | Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in rats. | 2006 | J. Neurochem. | pmid:16805835 |
| Vinod KY et al. | Effect of chronic ethanol exposure and its withdrawal on the endocannabinoid system. | 2006 | Neurochem. Int. | pmid:16822589 |
| Ghasemi M et al. | Effect of anandamide on nonadrenergic noncholinergic-mediated relaxation of rat corpus cavernosum. | 2006 | Eur. J. Pharmacol. | pmid:16824514 |
| Wagner JA et al. | 2-Arachidonylglycerol acting on CB1 cannabinoid receptors mediates delayed cardioprotection induced by nitric oxide in rat isolated hearts. | 2006 | J. Cardiovasc. Pharmacol. | pmid:16775503 |
| Bonechi C et al. | Nuclear magnetic resonance for studying recognition processes between anandamide and cannabinoid receptors. | 2006 | Eur J Med Chem | pmid:16837109 |
| Costa B et al. | AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain. | 2006 | Br. J. Pharmacol. | pmid:16770320 |
| Felder CC et al. | Cannabinoids biology: the search for new therapeutic targets. | 2006 | Mol. Interv. | pmid:16809476 |
| Yeh JH et al. | Effect of anandamide on cytosolic Ca(2+) levels and proliferation in canine renal tubular cells. | 2006 | Basic Clin. Pharmacol. Toxicol. | pmid:16623868 |
| Rösch S et al. | R(+)-methanandamide and other cannabinoids induce the expression of cyclooxygenase-2 and matrix metalloproteinases in human nonpigmented ciliary epithelial cells. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16330497 |
| Laviolette SR and Grace AA | The roles of cannabinoid and dopamine receptor systems in neural emotional learning circuits: implications for schizophrenia and addiction. | 2006 | Cell. Mol. Life Sci. | pmid:16699809 |
| Balas L et al. | Synthesis of a potential photoactivatable anandamide analog. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16682198 |
| Shouman B et al. | Endocannabinoids potently protect the newborn brain against AMPA-kainate receptor-mediated excitotoxic damage. | 2006 | Br. J. Pharmacol. | pmid:16682966 |
| Sade H et al. | Activation of large-conductance, Ca2+-activated K+ channels by cannabinoids. | 2006 | Am. J. Physiol., Cell Physiol. | pmid:16107501 |
| Wang H et al. | Fatty acid amide hydrolase deficiency limits early pregnancy events. | 2006 | J. Clin. Invest. | pmid:16886060 |
| Li J and Wang DH | Differential mechanisms mediating depressor and diuretic effects of anandamide. | 2006 | J. Hypertens. | pmid:17053550 |
| Krishtal O et al. | The agonists for nociceptors are ubiquitous, but the modulators are specific: P2X receptors in the sensory neurons are modulated by cannabinoids. | 2006 | Pflugers Arch. | pmid:16741755 |
| Wang Y et al. | A novel scintillation proximity assay for fatty acid amide hydrolase compatible with inhibitor screening. | 2006 | Anal. Biochem. | pmid:16707086 |
| Tzavara ET et al. | Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications. | 2006 | Biol. Psychiatry | pmid:16199010 |
| Schmidt A et al. | Determination of the endocannabinoid anandamide in human plasma by high-performance liquid chromatography. | 2006 | Biomed. Chromatogr. | pmid:16189813 |
| Bai X et al. | TASK channel expression in human placenta and cytotrophoblast cells. | 2006 | J. Soc. Gynecol. Investig. | pmid:16378911 |
| Hejazi N et al. | Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors. | 2006 | Mol. Pharmacol. | pmid:16332990 |
| Bojesen IN and Hansen HS | Effect of an unstirred layer on the membrane permeability of anandamide. | 2006 | J. Lipid Res. | pmid:16365480 |
| Dembiński A et al. | Cannabinoids in acute gastric damage and pancreatitis. | 2006 | J. Physiol. Pharmacol. | pmid:17218765 |
| D'Argenio G et al. | Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. | 2006 | FASEB J. | pmid:16403786 |
| Nakajima Y et al. | Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition. | 2006 | FEBS Lett. | pmid:16406050 |
| Suplita RL et al. | Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia. | 2006 | Neuropharmacology | pmid:16316669 |
| Avelino A and Cruz F | TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications. | 2006 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:16721555 |
| Murillo-Rodriguez E et al. | Diurnal variation of arachidonoylethanolamine, palmitoylethanolamide and oleoylethanolamide in the brain of the rat. | 2006 | Life Sci. | pmid:16434061 |
| Ligresti A et al. | New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis. | 2006 | Br. J. Pharmacol. | pmid:16284631 |
| Bir LS and Ercan S | Effects of intrathecal anandamide on somatosensory evoked responses in rats. | 2006 | Exp. Neurol. | pmid:16289169 |
| Urbani P et al. | New metabolically stable fatty acid amide ligands of cannabinoid receptors: Synthesis and receptor affinity studies. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16213718 |
| Malfitano AM et al. | Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis. | 2006 | J. Neuroimmunol. | pmid:16239036 |
| Glaser ST et al. | Endocannabinoids in the intact retina: 3 H-anandamide uptake, fatty acid amide hydrolase immunoreactivity and hydrolysis of anandamide. | 2005 Nov-Dec | Vis. Neurosci. | pmid:16469181 |
| Abalo R et al. | Evaluation of the effect of age on cannabinoid receptor functionality and expression in guinea-pig ileum longitudinal muscle-myenteric plexus preparations. | 2005 Jul 22-29 | Neurosci. Lett. | pmid:15936532 |
| Kurabayashi M et al. | 2-Arachidonoylglycerol increases in ischemia-reperfusion injury of the rat liver. | 2005 Jan-Feb | J Invest Surg | pmid:15804949 |
| Basavarajappa BS and Hungund BL | Role of the endocannabinoid system in the development of tolerance to alcohol. | 2005 Jan-Feb | Alcohol Alcohol. | pmid:15550443 |
| RodrÃguez de Fonseca F et al. | The endocannabinoid system: physiology and pharmacology. | 2005 Jan-Feb | Alcohol Alcohol. | pmid:15550444 |
| Oddi S et al. | Confocal microscopy and biochemical analysis reveal spatial and functional separation between anandamide uptake and hydrolysis in human keratinocytes. | 2005 | Cell. Mol. Life Sci. | pmid:15723173 |
| Rodella LF et al. | AM404, an inhibitor of anandamide reuptake decreases Fos-immunoreactivity in the spinal cord of neuropathic rats after non-noxious stimulation. | 2005 | Eur. J. Pharmacol. | pmid:15680264 |
| Oz M et al. | Additive effects of endogenous cannabinoid anandamide and ethanol on alpha7-nicotinic acetylcholine receptor-mediated responses in Xenopus Oocytes. | 2005 | J. Pharmacol. Exp. Ther. | pmid:15687372 |
| Mbvundula EC et al. | Effects of cannabinoids on nitric oxide production by chondrocytes and proteoglycan degradation in cartilage. | 2005 | Biochem. Pharmacol. | pmid:15670582 |
| Fowler CJ and Tiger G | Cyclooxygenation of the arachidonoyl side chain of 1-arachidonoylglycerol and related compounds block their ability to prevent anandamide and 2-oleoylglycerol metabolism by rat brain in vitro. | 2005 | Biochem. Pharmacol. | pmid:15794945 |
| Lambert DM and Fowler CJ | The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications. | 2005 | J. Med. Chem. | pmid:16078824 |
| Appendino G et al. | Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential. | 2005 | J. Pharmacol. Exp. Ther. | pmid:15356216 |
| O'Sullivan SE et al. | Vascular effects of delta 9-tetrahydrocannabinol (THC), anandamide and N-arachidonoyldopamine (NADA) in the rat isolated aorta. | 2005 | Eur. J. Pharmacol. | pmid:15659311 |
| Bojesen IN and Hansen HS | Membrane transport of anandamide through resealed human red blood cell membranes. | 2005 | J. Lipid Res. | pmid:15930521 |
| Fowler CJ et al. | The endocannabinoid signaling system: pharmacological and therapeutic aspects. | 2005 | Pharmacol. Biochem. Behav. | pmid:15935456 |
| De Petrocellis L and Di Marzo V | Lipids as regulators of the activity of transient receptor potential type V1 (TRPV1) channels. | 2005 | Life Sci. | pmid:15936040 |
| Balas L et al. | Synthesis of a photoactivatable probe of the anandamide re-uptake. | 2005 | Nat. Prod. Res. | pmid:15938150 |
| De Bank PA et al. | A spectrophotometric assay for fatty acid amide hydrolase suitable for high-throughput screening. | 2005 | Biochem. Pharmacol. | pmid:15794939 |
| Chen JZ et al. | Preferred conformations of endogenous cannabinoid ligand anandamide. | 2005 | Life Sci. | pmid:15826873 |
| Zhang N et al. | A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15764707 |
| Kvasnicka T | [Endocannabinoids--the new option in the treatment of metabolic syndrome and in smoking cessation]. | 2005 | Cas. Lek. Cesk. | pmid:15807291 |
| Minowa S et al. | Capsaicin- and anandamide-induced gastric acid secretion via vanilloid receptor type 1 (TRPV1) in rat brain. | 2005 | Brain Res. | pmid:15781048 |
| Siegmund SV and Brenner DA | Molecular pathogenesis of alcohol-induced hepatic fibrosis. | 2005 | Alcohol. Clin. Exp. Res. | pmid:16344593 |
| Kadoi Y et al. | Cannabinoid antagonist AM 281 reduces mortality rate and neurologic dysfunction after cecal ligation and puncture in rats. | 2005 | Crit. Care Med. | pmid:16276190 |
| Brizzi A et al. | Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors. | 2005 | J. Med. Chem. | pmid:16279794 |
| Singh Tahim A et al. | Inflammatory mediators convert anandamide into a potent activator of the vanilloid type 1 transient receptor potential receptor in nociceptive primary sensory neurons. | 2005 | Neuroscience | pmid:16198486 |