Ross RA et al. |
Pharmacological characterization of the anandamide cyclooxygenase metabolite: prostaglandin E2 ethanolamide. |
2002 |
J. Pharmacol. Exp. Ther. |
pmid:12023517
|
Walker VJ et al. |
Metabolism of Anandamide by Human Cytochrome P450 2J2 in the Reconstituted System and Human Intestinal Microsomes. |
2016 |
J. Pharmacol. Exp. Ther. |
pmid:27000802
|
Oz M et al. |
Additive effects of endogenous cannabinoid anandamide and ethanol on alpha7-nicotinic acetylcholine receptor-mediated responses in Xenopus Oocytes. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15687372
|
Porter AC et al. |
Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. |
2002 |
J. Pharmacol. Exp. Ther. |
pmid:12023533
|
Aceto MD et al. |
Anandamide, an endogenous cannabinoid, has a very low physical dependence potential. |
1998 |
J. Pharmacol. Exp. Ther. |
pmid:9808686
|
Esposito G et al. |
Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17545311
|
Gavva NR et al. |
AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15615864
|
Karanian DA et al. |
Endocannabinoid enhancement protects against kainic acid-induced seizures and associated brain damage. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17545313
|
Darmani NA |
The potent emetogenic effects of the endocannabinoid, 2-AG (2-arachidonoylglycerol) are blocked by delta(9)-tetrahydrocannabinol and other cannnabinoids. |
2002 |
J. Pharmacol. Exp. Ther. |
pmid:11752094
|
Appendino G et al. |
Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15356216
|
Kinsey SG et al. |
Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. |
2009 |
J. Pharmacol. Exp. Ther. |
pmid:19502530
|
Rockwell CE and Kaminski NE |
A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:15284281
|
Oz M et al. |
The endogenous cannabinoid anandamide inhibits alpha7 nicotinic acetylcholine receptor-mediated responses in Xenopus oocytes. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12766252
|
Patel S et al. |
Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activity. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12808005
|
Lichtman AH et al. |
Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:15229230
|
Snider NT et al. |
The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6. |
2008 |
J. Pharmacol. Exp. Ther. |
pmid:18698000
|
McDougle DR et al. |
Endocannabinoids anandamide and 2-arachidonoylglycerol are substrates for human CYP2J2 epoxygenase. |
2014 |
J. Pharmacol. Exp. Ther. |
pmid:25277139
|
Solinas M et al. |
Nicotinic facilitation of delta9-tetrahydrocannabinol discrimination involves endogenous anandamide. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17351107
|
Oz M et al. |
The endogenous cannabinoid anandamide inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17682128
|
Fride E et al. |
Low doses of anandamides inhibit pharmacological effects of delta 9-tetrahydrocannabinol. |
1995 |
J. Pharmacol. Exp. Ther. |
pmid:7853184
|
Miller LL et al. |
Effects of alterations in cannabinoid signaling, alone and in combination with morphine, on pain-elicited and pain-suppressed behavior in mice. |
2012 |
J. Pharmacol. Exp. Ther. |
pmid:22514333
|
Caprioli A et al. |
The novel reversible fatty acid amide hydrolase inhibitor ST4070 increases endocannabinoid brain levels and counteracts neuropathic pain in different animal models. |
2012 |
J. Pharmacol. Exp. Ther. |
pmid:22514334
|
Adams IB et al. |
Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs. |
1995 |
J. Pharmacol. Exp. Ther. |
pmid:7791088
|
Welch SP et al. |
Characterization of anandamide- and fluoroanandamide-induced antinociception and cross-tolerance to delta 9-THC after intrathecal administration to mice: blockade of delta 9-THC-induced antinociception. |
1995 |
J. Pharmacol. Exp. Ther. |
pmid:7791096
|
Ishioka N and Bukoski RD |
A role for N-arachidonylethanolamine (anandamide) as the mediator of sensory nerve-dependent Ca2+-induced relaxation. |
1999 |
J. Pharmacol. Exp. Ther. |
pmid:10087011
|
Matias I et al. |
Prostaglandin ethanolamides (prostamides): in vitro pharmacology and metabolism. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:14757851
|
Smith PB et al. |
The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice. |
1994 |
J. Pharmacol. Exp. Ther. |
pmid:8035318
|
Akerman S et al. |
Cannabinoid (CB1) receptor activation inhibits trigeminovascular neurons. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17018694
|
Akerman S et al. |
Anandamide is able to inhibit trigeminal neurons using an in vivo model of trigeminovascular-mediated nociception. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:14718591
|
Trezza V and Vanderschuren LJ |
Divergent effects of anandamide transporter inhibitors with different target selectivity on social play behavior in adolescent rats. |
2009 |
J. Pharmacol. Exp. Ther. |
pmid:18948500
|
McVey DC et al. |
Endocannabinoids induce ileitis in rats via the capsaicin receptor (VR1). |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12538826
|
McAllister SD et al. |
Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a xenopus oocyte expression system. |
1999 |
J. Pharmacol. Exp. Ther. |
pmid:10525080
|
Glaser ST and Kaczocha M |
Cyclooxygenase-2 mediates anandamide metabolism in the mouse brain. |
2010 |
J. Pharmacol. Exp. Ther. |
pmid:20702753
|
Orliac ML et al. |
Potentiation of anandamide effects in mesenteric beds isolated from endotoxemic rats. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12490589
|
Bonhaus DW et al. |
Dual activation and inhibition of adenylyl cyclase by cannabinoid receptor agonists: evidence for agonist-specific trafficking of intracellular responses. |
1998 |
J. Pharmacol. Exp. Ther. |
pmid:9864268
|
McCollum L et al. |
Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17379772
|
Wang Y et al. |
Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in Wistar rats fed a high-salt diet. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17308041
|
Varvel SA et al. |
Fatty acid amide hydrolase (-/-) mice exhibit an increased sensitivity to the disruptive effects of anandamide or oleamide in a working memory water maze task. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16352706
|
Showalter VM et al. |
Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. |
1996 |
J. Pharmacol. Exp. Ther. |
pmid:8819477
|
Rösch S et al. |
R(+)-methanandamide and other cannabinoids induce the expression of cyclooxygenase-2 and matrix metalloproteinases in human nonpigmented ciliary epithelial cells. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16330497
|
Lee M et al. |
Effects of putative cannabinoid receptor ligands, anandamide and 2-arachidonyl-glycerol, on immune function in B6C3F1 mouse splenocytes. |
1995 |
J. Pharmacol. Exp. Ther. |
pmid:7473135
|
Kraft B and Kress HG |
Indirect CB2 receptor and mediator-dependent stimulation of human whole-blood neutrophils by exogenous and endogenous cannabinoids. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:16055676
|
Snider NT et al. |
Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17272674
|
Fegley D et al. |
Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15579492
|
Martin BR et al. |
Cannabinoid properties of methylfluorophosphonate analogs. |
2000 |
J. Pharmacol. Exp. Ther. |
pmid:10945879
|
Lake KD et al. |
Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors. |
1997 |
J. Pharmacol. Exp. Ther. |
pmid:9190833
|
Willoughby KA et al. |
The biodisposition and metabolism of anandamide in mice. |
1997 |
J. Pharmacol. Exp. Ther. |
pmid:9223560
|
Hillard CJ |
Endocannabinoids and vascular function. |
2000 |
J. Pharmacol. Exp. Ther. |
pmid:10871291
|
Song ZH and Zhong M |
CB1 cannabinoid receptor-mediated cell migration. |
2000 |
J. Pharmacol. Exp. Ther. |
pmid:10871313
|
Di Marzo V et al. |
A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid. |
2002 |
J. Pharmacol. Exp. Ther. |
pmid:11861807
|
Glaser ST et al. |
Ex vivo imaging of fatty acid amide hydrolase activity and its inhibition in the mouse brain. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16278311
|
Muthian S et al. |
Synthesis and characterization of a fluorescent substrate for the N-arachidonoylethanolamine (anandamide) transmembrane carrier. |
2000 |
J. Pharmacol. Exp. Ther. |
pmid:10734181
|
Adams IB et al. |
Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain. |
1998 |
J. Pharmacol. Exp. Ther. |
pmid:9495885
|
Fowler CJ et al. |
Ibuprofen inhibits rat brain deamidation of anandamide at pharmacologically relevant concentrations. Mode of inhibition and structure-activity relationship. |
1997 |
J. Pharmacol. Exp. Ther. |
pmid:9353392
|
Brodkin J and Moerschbaecher JM |
SR141716A antagonizes the disruptive effects of cannabinoid ligands on learning in rats. |
1997 |
J. Pharmacol. Exp. Ther. |
pmid:9316868
|
Li G et al. |
Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes. |
2016 |
J. Pharmacol. Exp. Ther. |
pmid:27189966
|
Thomas KC et al. |
Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17332266
|
Tamaki C et al. |
Anandamide induces endothelium-dependent vasoconstriction and CGRPergic nerve-mediated vasodilatation in the rat mesenteric vascular bed. |
2012 |
J. Pharmacol. Sci. |
pmid:22510966
|
Sun Y et al. |
Cannabinoid receptor activation disrupts the internal structure of hippocampal sharp wave-ripple complexes. |
2012 |
J. Pharmacol. Sci. |
pmid:22293299
|
Frazier CJ |
Key questions of endocannabinoid signalling in the CNS: which, where and when? |
2011 |
J. Physiol. (Lond.) |
pmid:22001725
|
Chaytor AT et al. |
The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication. |
1999 |
J. Physiol. (Lond.) |
pmid:10523421
|
Kollarik M and Undem BJ |
Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice. |
2004 |
J. Physiol. (Lond.) |
pmid:14634201
|
Campanucci VA et al. |
A novel O2-sensing mechanism in rat glossopharyngeal neurones mediated by a halothane-inhibitable background K+ conductance. |
2003 |
J. Physiol. (Lond.) |
pmid:12640017
|
Han J et al. |
Properties and modulation of the G protein-coupled K+ channel in rat cerebellar granule neurons: ATP versus phosphatidylinositol 4,5-bisphosphate. |
2003 |
J. Physiol. (Lond.) |
pmid:12807991
|
Szabo B et al. |
Depolarization-induced retrograde synaptic inhibition in the mouse cerebellar cortex is mediated by 2-arachidonoylglycerol. |
2006 |
J. Physiol. (Lond.) |
pmid:16973696
|
Perrier JF et al. |
5-HT1A receptors increase excitability of spinal motoneurons by inhibiting a TASK-1-like K+ current in the adult turtle. |
2003 |
J. Physiol. (Lond.) |
pmid:12626670
|
Pacher P et al. |
Haemodynamic profile and responsiveness to anandamide of TRPV1 receptor knock-out mice. |
2004 |
J. Physiol. (Lond.) |
pmid:15121805
|
Jennings EA et al. |
The actions of anandamide on rat superficial medullary dorsal horn neurons in vitro. |
2003 |
J. Physiol. (Lond.) |
pmid:12562891
|
Hofmann ME et al. |
Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism. |
2011 |
J. Physiol. (Lond.) |
pmid:21646412
|
Steiner AA et al. |
The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors. |
2011 |
J. Physiol. (Lond.) |
pmid:21486787
|
Poblete IM et al. |
Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed. |
2005 |
J. Physiol. (Lond.) |
pmid:16081483
|
Vellani V et al. |
Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide. |
2001 |
J. Physiol. (Lond.) |
pmid:11483711
|
Straiker A and Mackie K |
Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones. |
2005 |
J. Physiol. (Lond.) |
pmid:16179366
|
Matta JA et al. |
TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. |
2007 |
J. Physiol. (Lond.) |
pmid:17038422
|
Harris D et al. |
Characterization of vasorelaxant responses to anandamide in the rat mesenteric arterial bed. |
2002 |
J. Physiol. (Lond.) |
pmid:11897858
|
Lin YS and Lee LY |
Stimulation of pulmonary vagal C-fibres by anandamide in anaesthetized rats: role of vanilloid type 1 receptors. |
2002 |
J. Physiol. (Lond.) |
pmid:11897863
|
Yoshino H et al. |
Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex. |
2011 |
J. Physiol. (Lond.) |
pmid:21807615
|
Di S et al. |
Activity-dependent release and actions of endocannabinoids in the rat hypothalamic supraoptic nucleus. |
2005 |
J. Physiol. (Lond.) |
pmid:16239276
|
Van der Kloot W et al. |
Calcitonin gene-related peptide acts presynaptically to increase quantal size and output at frog neuromuscular junctions. |
1998 |
J. Physiol. (Lond.) |
pmid:9508830
|
Alger BE |
Endocannabinoids at the synapse a decade after the dies mirabilis (29 March 2001): what we still do not know. |
2012 |
J. Physiol. (Lond.) |
pmid:22289914
|
Williams MA et al. |
The group IV afferent neuron expresses multiple receptor alterations in cardiomyopathyic rats: evidence at the cannabinoid CB1 receptor. |
2008 |
J. Physiol. (Lond.) |
pmid:18063665
|
Gamelin FX et al. |
Effects of chronic exercise on the endocannabinoid system in Wistar rats with high-fat diet-induced obesity. |
2016 |
J. Physiol. Biochem. |
pmid:26880264
|
Warzecha Z et al. |
Role of sensory nerves in gastroprotective effect of anandamide in rats. |
2011 |
J. Physiol. Pharmacol. |
pmid:21673369
|
Engel MA et al. |
Ulcerative colitis in AKR mice is attenuated by intraperitoneally administered anandamide. |
2008 |
J. Physiol. Pharmacol. |
pmid:19212003
|
Grzeda E et al. |
Bi-directional CB1 receptor-mediated cardiovascular effects of cannabinoids in anaesthetized rats: role of the paraventricular nucleus. |
2015 |
J. Physiol. Pharmacol. |
pmid:26084216
|
Dembiński A et al. |
Cannabinoids in acute gastric damage and pancreatitis. |
2006 |
J. Physiol. Pharmacol. |
pmid:17218765
|
Vinklerová J et al. |
Inhibition of methamphetamine self-administration in rats by cannabinoid receptor antagonist AM 251. |
2002 |
J. Psychopharmacol. (Oxford) |
pmid:12095072
|
Ashton CH et al. |
Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential. |
2005 |
J. Psychopharmacol. (Oxford) |
pmid:15888515
|
Aguilar DD et al. |
THC and endocannabinoids differentially regulate neuronal activity in the prefrontal cortex and hippocampus in the subchronic PCP model of schizophrenia. |
2016 |
J. Psychopharmacol. (Oxford) |
pmid:26510449
|
Almeida-Santos AF et al. |
2-Arachidonoylglycerol endocannabinoid signaling coupled to metabotropic glutamate receptor type-5 modulates anxiety-like behavior in the rat ventromedial prefrontal cortex. |
2017 |
J. Psychopharmacol. (Oxford) |
pmid:28440729
|
Pamplona FA and Takahashi RN |
Psychopharmacology of the endocannabinoids: far beyond anandamide. |
2012 |
J. Psychopharmacol. (Oxford) |
pmid:21652605
|
Potvin S et al. |
Endogenous cannabinoids in patients with schizophrenia and substance use disorder during quetiapine therapy. |
2008 |
J. Psychopharmacol. (Oxford) |
pmid:18308802
|
Butler RK et al. |
Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase. |
2012 |
J. Psychopharmacol. (Oxford) |
pmid:21926424
|
Bai X et al. |
TASK channel expression in human placenta and cytotrophoblast cells. |
2006 |
J. Soc. Gynecol. Investig. |
pmid:16378911
|
Maia J et al. |
The endocannabinoid system expression in the female reproductive tract is modulated by estrogen. |
2017 |
J. Steroid Biochem. Mol. Biol. |
pmid:28743542
|
Miyato H et al. |
Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. |
2009 |
J. Surg. Res. |
pmid:19394652
|
Gratzke C et al. |
Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. |
2009 |
J. Urol. |
pmid:19237169
|
Habayeb OM et al. |
Plasma anandamide concentration and pregnancy outcome in women with threatened miscarriage. |
2008 |
JAMA |
pmid:18334688
|
Maccarrone M |
Anandamide as a marker of human disease. |
2008 |
JAMA |
pmid:18632539
|
Mikawa Y et al. |
Ocular activity of topically administered anandamide in the rabbit. |
1997 Jul-Aug |
Jpn. J. Ophthalmol. |
pmid:9304433
|