| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
| Dyskinesia, Drug-Induced | D004409 | 15 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Ventricular Fibrillation | D014693 | 16 associated lipids |
| Parkinson Disease, Secondary | D010302 | 17 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Pancreatitis, Acute Necrotizing | D019283 | 18 associated lipids |
| Hypothermia | D007035 | 19 associated lipids |
| Peptic Ulcer | D010437 | 19 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kurihara J et al. | 2-Arachidonoylglycerol and anandamide oppositely modulate norepinephrine release from the rat heart sympathetic nerves. | 2001 | Jpn. J. Pharmacol. | pmid:11676206 |
| Haruta C | [Effects of anandamide on IL-11 production through the TRPV1 of human periodontal ligament cells]. | 2012 | Kokubyo Gakkai Zasshi | pmid:22568077 |
| Ito T et al. | Propofol protects against anandamide-induced injury in human umbilical vein endothelial cells. | 2011 | Kurume Med J | pmid:22027193 |
| Huang L et al. | Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor. | 2011 | Lab. Invest. | pmid:21464819 |
| Gurwitz D and Weizman A | Fatty acid amide hydrolase inhibitors and the marijuana debate. | 2001 | Lancet | pmid:11705595 |
| Senior K | Endogenously produced cannabinoids and liver cirrhosis. | 2001 | Lancet | pmid:11454385 |
| Bradbury J | Small part of cannabis puzzle solved by animal studies. | 2001 | Lancet | pmid:11498223 |
| Lockwood CJ | Prediction of pregnancy loss. | 2000 | Lancet | pmid:10776739 |
| Maccarrone M et al. | Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage. | 2000 | Lancet | pmid:10776746 |
| Mazzola C et al. | Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-alpha nuclear receptors. | 2009 | Learn. Mem. | pmid:19403796 |
| Hunter SA and Burstein SH | Receptor mediation in cannabinoid stimulated arachidonic acid mobilization and anandamide synthesis. | 1997 | Life Sci. | pmid:9126878 |
| Zenor BN et al. | Endocrine and other responses to acute administration of cannabinoid compounds to non-stressed male calves. | 1999 | Life Sci. | pmid:10416818 |
| Kopczyńska B | The contribution of VR1 and CB1 receptors and the role of the afferent vagal pathway in modelling of cardio-respiratory effects of anandamide in rats. | 2007 | Life Sci. | pmid:17379256 |
| Ralevic V et al. | Cannabinoid modulation of sensory neurotransmission via cannabinoid and vanilloid receptors: roles in regulation of cardiovascular function. | 2002 | Life Sci. | pmid:12354577 |
| Pate DW et al. | Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits. | 1998 | Life Sci. | pmid:9851310 |
| Glaser ST et al. | Anandamide transport: a critical review. | 2005 | Life Sci. | pmid:15979096 |
| Reis GM et al. | Opioid receptor and NO/cGMP pathway as a mechanism of peripheral antinociceptive action of the cannabinoid receptor agonist anandamide. | 2009 | Life Sci. | pmid:19576231 |
| Ueda N et al. | N-acylphosphatidylethanolamine-hydrolyzing phospholipase D: a novel enzyme of the beta-lactamase fold family releasing anandamide and other N-acylethanolamines. | 2005 | Life Sci. | pmid:15949819 |
| Lam FF et al. | Pharmacological characterization of receptor types mediating the dilator action of anandamide on blood vessels of the rat knee joint. | 2007 | Life Sci. | pmid:17275857 |
| De Petrocellis L and Di Marzo V | Lipids as regulators of the activity of transient receptor potential type V1 (TRPV1) channels. | 2005 | Life Sci. | pmid:15936040 |
| Wiley JL et al. | Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice. | 2006 | Life Sci. | pmid:16978656 |
| Mallet PE and Beninger RJ | Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. | 1998 | Life Sci. | pmid:9651110 |
| Helyes Z et al. | Inhibitory effect of anandamide on resiniferatoxin-induced sensory neuropeptide release in vivo and neuropathic hyperalgesia in the rat. | 2003 | Life Sci. | pmid:12941436 |
| Berdyshev E et al. | Effects of cannabinoid receptor ligands on LPS-induced pulmonary inflammation in mice. | 1998 | Life Sci. | pmid:9718090 |
| Musty RE et al. | A review of recent advances in cannabinoid research and the 1994 International Symposium on Cannabis and the Cannabinoids. | 1995 | Life Sci. | pmid:7776816 |
| Kraft B et al. | Cannabinoid receptor-independent suppression of the superoxide generation of human neutrophils (PMN) by CP55 940, but not by anandamide. | 2004 | Life Sci. | pmid:15193957 |
| Omeir RL et al. | Arachidonoyl ethanolamide-[1,2-14C] as a substrate for anandamide amidase. | 1995 | Life Sci. | pmid:7776824 |
| Romero J et al. | The endogenous cannabinoid receptor ligand, anandamide, inhibits the motor behavior: role of nigrostriatal dopaminergic neurons. | 1995 | Life Sci. | pmid:7776829 |
| Adams IB et al. | Pharmacological and behavioral evaluation of alkylated anandamide analogs. | 1995 | Life Sci. | pmid:7776830 |
| Wenger T et al. | Effects of anandamide (endogen cannabinoid) on anterior pituitary hormone secretion in adult ovariectomized rats. | 1995 | Life Sci. | pmid:7776832 |
| Cabral GA et al. | Anandamide inhibits macrophage-mediated killing of tumor necrosis factor-sensitive cells. | 1995 | Life Sci. | pmid:7776833 |
| Arizzi MN et al. | Behavioral effects of inhibition of cannabinoid metabolism: The amidase inhibitor AM374 enhances the suppression of lever pressing produced by exogenously administered anandamide. | 2004 | Life Sci. | pmid:14672756 |
| Martin BR et al. | Discovery and characterization of endogenous cannabinoids. | 1999 | Life Sci. | pmid:10462059 |
| Khanolkar AD and Makriyannis A | Structure-activity relationships of anandamide, an endogenous cannabinoid ligand. | 1999 | Life Sci. | pmid:10462061 |
| Howlett AC et al. | Signal transduction of eicosanoid CB1 receptor ligands. | 1999 | Life Sci. | pmid:10462062 |
| Di Marzo V | Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators. | 1999 | Life Sci. | pmid:10462065 |
| Jarho P et al. | Hydroxypropyl-beta-cyclodextrin increases aqueous solubility and stability of anandamide. | 1996 | Life Sci. | pmid:8602110 |
| Soneji ND et al. | Effects of cannabinoids on capsaicin receptor activity following exposure of primary sensory neurons to inflammatory mediators. | 2010 | Life Sci. | pmid:20598325 |
| Romero TR et al. | Probable involvement of Ca(2+)-activated Cl(-) channels (CaCCs) in the activation of CB1 cannabinoid receptors. | 2013 | Life Sci. | pmid:23123446 |
| Tóth A et al. | Different vanilloid agonists cause different patterns of calcium response in CHO cells heterologously expressing rat TRPV1. | 2005 | Life Sci. | pmid:15820503 |
| Chen JZ et al. | Preferred conformations of endogenous cannabinoid ligand anandamide. | 2005 | Life Sci. | pmid:15826873 |
| Roa-Coria JE et al. | N-(4-Methoxy-2-nitrophenyl)hexadecanamide, a palmitoylethanolamide analogue, reduces formalin-induced nociception. | 2012 | Life Sci. | pmid:23069585 |
| Reis GM et al. | Endogenous cannabinoid receptor agonist anandamide induces peripheral antinociception by activation of ATP-sensitive K+ channels. | 2011 | Life Sci. | pmid:21277864 |
| Wenger T et al. | The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female rats. | 2002 | Life Sci. | pmid:11883716 |
| Sasaki T and Chang MC | N-arachidonylethanolamine (anandamide) formation from N-arachidonylphosphatidylethanolamine in rat brain membranes. | 1997 | Life Sci. | pmid:9365227 |
| González S et al. | Extrapyramidal and neuroendocrine effects of AM404, an inhibitor of the carrier-mediated transport of anandamide. | 1999 | Life Sci. | pmid:10447218 |
| Wiley JL et al. | Influence of phenylmethylsulfonyl fluoride on anandamide brain levels and pharmacological effects. | 2000 | Life Sci. | pmid:10983852 |
| Murillo-Rodriguez E et al. | Diurnal variation of arachidonoylethanolamine, palmitoylethanolamide and oleoylethanolamide in the brain of the rat. | 2006 | Life Sci. | pmid:16434061 |
| Wenger T et al. | Effects of anandamide on gestation in pregnant rats. | 1997 | Life Sci. | pmid:9199480 |
| Holt S et al. | Lipopolysaccharide-induced pulmonary inflammation is not accompanied by a release of anandamide into the lavage fluid or a down-regulation of the activity of fatty acid amide hydrolase. | 2004 | Life Sci. | pmid:15530507 |
| Czikora à et al. | Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation. | 2012 | Life Sci. | pmid:22285599 |
| Habayeb OM et al. | Endogenous cannabinoids: metabolism and their role in reproduction. | 2002 | Life Sci. | pmid:12148689 |
| Liu WM et al. | Effects of anandamide on embryo implantation in the mouse. | 2002 | Life Sci. | pmid:12137909 |
| Tóth A et al. | Arachidonyl dopamine as a ligand for the vanilloid receptor VR1 of the rat. | 2003 | Life Sci. | pmid:12759142 |
| Forsell PK et al. | Metabolism of anandamide into eoxamides by 15-lipoxygenase-1 and glutathione transferases. | 2012 | Lipids | pmid:22684912 |
| Di Marzo V et al. | Metabolism of anandamide and 2-arachidonoylglycerol: an historical overview and some recent developments. | 1999 | Lipids | pmid:10419192 |
| Hansen HS et al. | Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity. | 1999 | Lipids | pmid:10419193 |
| Schmid PC et al. | Anandamide and other N-acylethanolamines in human tumors. | 2002 | Lipids | pmid:12458627 |
| Alvheim AR et al. | Dietary linoleic acid elevates the endocannabinoids 2-AG and anandamide and promotes weight gain in mice fed a low fat diet. | 2014 | Lipids | pmid:24081493 |
| Naccarato M et al. | Possible Anandamide and Palmitoylethanolamide involvement in human stroke. | 2010 | Lipids Health Dis | pmid:20470384 |
| Berge K et al. | Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men. | 2013 | Lipids Health Dis | pmid:23706001 |
| Annuzzi G et al. | Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients. | 2010 | Lipids Health Dis | pmid:20426869 |
| Quartu M et al. | Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion. | 2017 | Lipids Health Dis | pmid:28103941 |
| Yang YY et al. | Inhibition of hepatic tumour necrosis factor-alpha attenuates the anandamide-induced vasoconstrictive response in cirrhotic rat livers. | 2009 | Liver Int. | pmid:19413671 |
| Caraceni P et al. | Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. | 2010 | Liver Int. | pmid:19840245 |
| Yang YY et al. | Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. | 2007 | Liver Int. | pmid:17845532 |
| Ying-Ying Y and Lin HC | Endocannabinoids and non-endocannabinoid fatty acid amides in cirrhosis. | 2010 | Liver Int. | pmid:20408944 |
| Fernández-Rodriguez CM et al. | Circulating endogenous cannabinoid anandamide and portal, systemic and renal hemodynamics in cirrhosis. | 2004 | Liver Int. | pmid:15482346 |
| Piyanova A et al. | Age-related changes in the endocannabinoid system in the mouse hippocampus. | 2015 | Mech. Ageing Dev. | pmid:26278494 |
| Zohrabi-Kalantari V et al. | 4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of anandamide analogs. | 2013 | Med Chem | pmid:23157226 |
| Schlabritz-Loutsevitch N et al. | Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity. | 2016 | Med. Hypotheses | pmid:27959272 |
| Coppola M and Mondola R | Palmitoylethanolamide: from endogenous cannabimimetic substance to innovative medicine for the treatment of cannabis dependence. | 2013 | Med. Hypotheses | pmid:23896215 |
| Kudalkar SN et al. | Assay of Endocannabinoid Oxidation by Cyclooxygenase-2. | 2016 | Methods Mol. Biol. | pmid:27245906 |
| van Zadelhoff G and van der Stelt M | Oxygenation of Anandamide by Lipoxygenases. | 2016 | Methods Mol. Biol. | pmid:27245907 |
| Fezza F et al. | Methods to assay anandamide hydrolysis and transport in synaptosomes. | 2006 | Methods Mol. Med. | pmid:16506407 |
| Chen P et al. | Induction of cyclooxygenase-2 by anandamide in cerebral microvascular endothelium. | 2005 | Microvasc. Res. | pmid:15797258 |
| Bari M et al. | New insights into endocannabinoid degradation and its therapeutic potential. | 2006 | Mini Rev Med Chem | pmid:16515464 |
| Marco EM and Viveros MP | The critical role of the endocannabinoid system in emotional homeostasis: avoiding excess and deficiencies. | 2009 | Mini Rev Med Chem | pmid:19929814 |
| Lu W et al. | Voltage-independent sodium channels emerge for an expression of activity-induced spontaneous spikes in GABAergic neurons. | 2014 | Mol Brain | pmid:24886791 |
| Ma C et al. | Anti-carcinogenic activity of anandamide on human glioma in vitro and in vivo. | 2016 | Mol Med Rep | pmid:26707955 |
| Gurwitz D and Kloog Y | Do endogenous cannabinoids contribute to HIV-mediated immune failure? | 1998 | Mol Med Today | pmid:9612798 |
| Banni S and Di Marzo V | Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. | 2010 | Mol Nutr Food Res | pmid:20013888 |
| Rajaraman G et al. | G protein coupled receptor 18: A potential role for endocannabinoid signaling in metabolic dysfunction. | 2016 | Mol Nutr Food Res | pmid:26337420 |
| Guasti L et al. | Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. | 2009 | Mol Pain | pmid:19570201 |
| Woo DH et al. | Direct activation of transient receptor potential vanilloid 1(TRPV1) by diacylglycerol (DAG). | 2008 | Mol Pain | pmid:18826653 |
| Kuc C et al. | Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. | 2012 | Mol. Carcinog. | pmid:21432910 |
| Van Dross RT | Metabolism of anandamide by COX-2 is necessary for endocannabinoid-induced cell death in tumorigenic keratinocytes. | 2009 | Mol. Carcinog. | pmid:19148897 |
| Triggle CR et al. | The endothelium in health and disease: a discussion of the contribution of non-nitric oxide endothelium-derived vasoactive mediators to vascular homeostasis in normal vessels and in type II diabetes. | 2004 | Mol. Cell. Biochem. | pmid:15524164 |
| Qureshi J et al. | Identification and characterization of a novel synthetic cannabinoid CP 55,940 binder in rat brain cytosol. | 1998 | Mol. Cell. Biochem. | pmid:9562238 |
| González-Mariscal I et al. | Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice. | 2016 | Mol. Cell. Endocrinol. | pmid:26724516 |
| Battista N et al. | The role of endocannabinoids in gonadal function and fertility along the evolutionary axis. | 2012 | Mol. Cell. Endocrinol. | pmid:22305972 |
| Cavuoto P et al. | Effects of cannabinoid receptors on skeletal muscle oxidative pathways. | 2007 | Mol. Cell. Endocrinol. | pmid:17270342 |
| Oláh M et al. | The role of endocannabinoids in the regulation of luteinizing hormone and prolactin release. Differences between the effects of AEA and 2AG. | 2008 | Mol. Cell. Endocrinol. | pmid:18308464 |
| Migliarini B and Carnevali O | Anandamide modulates growth and lipid metabolism in the zebrafish Danio rerio. | 2008 | Mol. Cell. Endocrinol. | pmid:18342434 |
| Catanzaro G et al. | Effect of capacitation on the endocannabinoid system of mouse sperm. | 2011 | Mol. Cell. Endocrinol. | pmid:21723369 |
| Musella A et al. | TRPV1 channels facilitate glutamate transmission in the striatum. | 2009 | Mol. Cell. Neurosci. | pmid:18930149 |
| Fezza F et al. | Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting. | 2014 | Mol. Cell. Neurosci. | pmid:25064144 |
| Krishnan G and Chatterjee N | Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicity. | 2014 | Mol. Cell. Neurosci. | pmid:24418364 |
| Brighton PJ et al. | Characterization of anandamide-stimulated cannabinoid receptor signaling in human ULTR myometrial smooth muscle cells. | 2009 | Mol. Endocrinol. | pmid:19477951 |
| Sanchez AM et al. | The molecular connections between the cannabinoid system and endometriosis. | 2012 | Mol. Hum. Reprod. | pmid:22923487 |