Rajesh M et al. |
Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy. |
2012 |
Diabetes |
pmid:22315315
|
Shi RZ et al. |
Decreased anandamide transporter activity and calcitonin gene-related peptide production in spontaneously hypertensive rats: role of angiotensin II. |
2012 |
Eur. J. Pharmacol. |
pmid:22318155
|
Battista N et al. |
The role of endocannabinoids in gonadal function and fertility along the evolutionary axis. |
2012 |
Mol. Cell. Endocrinol. |
pmid:22305972
|
Liu J et al. |
Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice. |
2012 |
Gastroenterology |
pmid:22307032
|
Fowler CJ |
Anandamide uptake explained? |
2012 |
Trends Pharmacol. Sci. |
pmid:22297258
|
Izzo AA et al. |
Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. |
2012 |
Br. J. Pharmacol. |
pmid:22300105
|
Chon SH et al. |
Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity. |
2012 |
PLoS ONE |
pmid:22937137
|
Neelamegan D et al. |
Identification and recombinant expression of anandamide hydrolyzing enzyme from Dictyostelium discoideum. |
2012 |
BMC Microbiol. |
pmid:22730904
|
Moreno-Sanz G et al. |
Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier. |
2012 |
Br. J. Pharmacol. |
pmid:22774772
|
Rettori E et al. |
Anti-inflammatory effect of the endocannabinoid anandamide in experimental periodontitis and stress in the rat. |
2012 |
Neuroimmunomodulation |
pmid:22777139
|
Luchicchi A and Pistis M |
Anandamide and 2-arachidonoylglycerol: pharmacological properties, functional features, and emerging specificities of the two major endocannabinoids. |
2012 |
Mol. Neurobiol. |
pmid:22801993
|
Krishnan G and Chatterjee N |
Endocannabinoids alleviate proinflammatory conditions by modulating innate immune response in muller glia during inflammation. |
2012 |
Glia |
pmid:22807196
|
Romano MR and Lograno MD |
Involvement of the peroxisome proliferator-activated receptor (PPAR) alpha in vascular response of endocannabinoids in the bovine ophthalmic artery. |
2012 |
Eur. J. Pharmacol. |
pmid:22429572
|
Xiong W et al. |
A common molecular basis for exogenous and endogenous cannabinoid potentiation of glycine receptors. |
2012 |
J. Neurosci. |
pmid:22496565
|
Chicca A et al. |
Evidence for bidirectional endocannabinoid transport across cell membranes. |
2012 |
J. Biol. Chem. |
pmid:22879589
|
Leweke FM et al. |
Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. |
2012 |
Transl Psychiatry |
pmid:22832859
|
Kuc C et al. |
Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. |
2012 |
Mol. Carcinog. |
pmid:21432910
|
Skaper SD and Di Marzo V |
Endocannabinoids in nervous system health and disease: the big picture in a nutshell. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108539
|
Di Marzo V and De Petrocellis L |
Why do cannabinoid receptors have more than one endogenous ligand? |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108541
|
Puighermanal E et al. |
Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108544
|
Starowicz K and Przewlocka B |
Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108547
|
Rani Sagar D et al. |
Dynamic changes to the endocannabinoid system in models of chronic pain. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108548
|
Campos AC et al. |
Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. |
2012 |
Philos. Trans. R. Soc. Lond., B, Biol. Sci. |
pmid:23108553
|
Lipina C et al. |
New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance. |
2012 |
Bioessays |
pmid:22674489
|
Zoerner AA et al. |
Simultaneous UPLC-MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction. |
2012 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:21752730
|
Goonawardena AV et al. |
Pharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus. |
2011 Oct-Nov |
Neuropharmacology |
pmid:21767554
|
Frazier CJ |
Key questions of endocannabinoid signalling in the CNS: which, where and when? |
2011 |
J. Physiol. (Lond.) |
pmid:22001725
|
Ito T et al. |
Propofol protects against anandamide-induced injury in human umbilical vein endothelial cells. |
2011 |
Kurume Med J |
pmid:22027193
|
Alenmyr L et al. |
TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo. |
2011 |
Clin Physiol Funct Imaging |
pmid:21981454
|
Hayase T |
Differential effects of TRPV1 receptor ligands against nicotine-induced depression-like behaviors. |
2011 |
BMC Pharmacol. |
pmid:21767384
|
Romero TR et al. |
The neuronal NO synthase participation in the peripheral antinociception mechanism induced by several analgesic drugs. |
2011 |
Nitric Oxide |
pmid:21875681
|
Dean C |
Cannabinoid and GABA modulation of sympathetic nerve activity and blood pressure in the dorsal periaqueductal gray of the rat. |
2011 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:21940402
|
Sridar C et al. |
Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6. |
2011 |
Drug Metab. Dispos. |
pmid:21289075
|
Andrianova EL et al. |
In vitro effects of anandamide and prostamide e2 on normal and transformed nerve cells. |
2011 |
Bull. Exp. Biol. Med. |
pmid:22442796
|
Kim HY et al. |
A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21810478
|
Brighton PJ et al. |
Characterization of the endocannabinoid system, CB(1) receptor signalling and desensitization in human myometrium. |
2011 |
Br. J. Pharmacol. |
pmid:21486283
|
Walentiny DM et al. |
The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. |
2011 |
Eur. J. Pharmacol. |
pmid:21300050
|
Naidoo V et al. |
A new generation fatty acid amide hydrolase inhibitor protects against kainate-induced excitotoxicity. |
2011 |
J. Mol. Neurosci. |
pmid:21069475
|
Gomes FV et al. |
Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice. |
2011 |
Prog. Neuropsychopharmacol. Biol. Psychiatry |
pmid:21111767
|
Cassano T et al. |
Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice. |
2011 |
Psychopharmacology (Berl.) |
pmid:21042794
|
Bari M et al. |
Characterization of the endocannabinoid system in mouse embryonic stem cells. |
2011 |
Stem Cells Dev. |
pmid:20446814
|
Justinová Z et al. |
Reinforcing and neurochemical effects of cannabinoid CB1 receptor agonists, but not cocaine, are altered by an adenosine A2A receptor antagonist. |
2011 |
Addict Biol |
pmid:21054689
|
Long JZ et al. |
An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase. |
2011 |
J. Lipid Res. |
pmid:21097653
|
Hofmann ME et al. |
Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism. |
2011 |
J. Physiol. (Lond.) |
pmid:21646412
|
MartÃn-Couce L et al. |
Development of endocannabinoid-based chemical probes for the study of cannabinoid receptors. |
2011 |
J. Med. Chem. |
pmid:21675776
|
Romani R et al. |
Anandamide and its congeners inhibit human plasma butyrylcholinesterase. Possible new roles for these endocannabinoids? |
2011 |
Biochimie |
pmid:21664223
|
Weller K et al. |
TRPV1, TRPA1, and CB1 in the isolated vagus nerve--axonal chemosensitivity and control of neuropeptide release. |
2011 |
Neuropeptides |
pmid:21868092
|
Khanna IK and Alexander CW |
Fatty acid amide hydrolase inhibitors--progress and potential. |
2011 |
CNS Neurol Disord Drug Targets |
pmid:21631410
|
Aberturas MR et al. |
Anandamide-loaded nanoparticles: preparation and characterization. |
2011 |
J Microencapsul |
pmid:21425945
|
Pinar-Sueiro S et al. |
[Cannabinoid applications in glaucoma]. |
2011 |
Arch Soc Esp Oftalmol |
pmid:21414525
|
Mukhopadhyay B et al. |
Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:21383171
|
Rossi S et al. |
Cannabinoid CB1 receptors regulate neuronal TNF-α effects in experimental autoimmune encephalomyelitis. |
2011 |
Brain Behav. Immun. |
pmid:21473912
|
Gamaleddin I et al. |
The selective anandamide transport inhibitor VDM11 attenuates reinstatement of nicotine seeking behaviour, but does not affect nicotine intake. |
2011 |
Br. J. Pharmacol. |
pmid:21501143
|
Howlett AC et al. |
Endocannabinoid tone versus constitutive activity of cannabinoid receptors. |
2011 |
Br. J. Pharmacol. |
pmid:21545414
|
Carr RL et al. |
Effect of developmental chlorpyrifos exposure, on endocannabinoid metabolizing enzymes, in the brain of juvenile rats. |
2011 |
Toxicol. Sci. |
pmid:21507991
|
Qi J et al. |
Painful pathways induced by TLR stimulation of dorsal root ganglion neurons. |
2011 |
J. Immunol. |
pmid:21515789
|
Steiner AA et al. |
The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors. |
2011 |
J. Physiol. (Lond.) |
pmid:21486787
|
Izzo AA and Deutsch DG |
Unique pathway for anandamide synthesis and liver regeneration. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:21490298
|
Chiba T et al. |
A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells. |
2011 |
J. Pharm. Pharmacol. |
pmid:21492165
|
Huang L et al. |
Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor. |
2011 |
Lab. Invest. |
pmid:21464819
|
Dean C |
Endocannabinoid modulation of sympathetic and cardiovascular responses to acute stress in the periaqueductal gray of the rat. |
2011 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:21228344
|
Ishiguro H et al. |
Functional polymorphism in the GPR55 gene is associated with anorexia nervosa. |
2011 |
Synapse |
pmid:20506567
|
Morera-Herreras T et al. |
Nigrostriatal denervation changes the effect of cannabinoids on subthalamic neuronal activity in rats. |
2011 |
Psychopharmacology (Berl.) |
pmid:20959968
|
Hollis JH et al. |
The endocannabinoid arachidonylethanolamide attenuates aspects of lipopolysaccharide-induced changes in energy intake, energy expenditure and hypothalamic Fos expression. |
2011 |
J. Neuroimmunol. |
pmid:21262543
|
Zschenderlein C et al. |
Capsaicin-induced changes in LTP in the lateral amygdala are mediated by TRPV1. |
2011 |
PLoS ONE |
pmid:21249195
|
Garami A et al. |
Thermoregulatory phenotype of the Trpv1 knockout mouse: thermoeffector dysbalance with hyperkinesis. |
2011 |
J. Neurosci. |
pmid:21289181
|
Wang W et al. |
Enhancement of apamin-sensitive medium afterhyperpolarization current by anandamide and its role in excitability control in cultured hippocampal neurons. |
2011 |
Neuropharmacology |
pmid:21272594
|
Reis GM et al. |
Endogenous cannabinoid receptor agonist anandamide induces peripheral antinociception by activation of ATP-sensitive K+ channels. |
2011 |
Life Sci. |
pmid:21277864
|
Kawahara H et al. |
Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. |
2011 |
Br. J. Pharmacol. |
pmid:21175570
|
Di Marzo V |
Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight. |
2011 |
Nat. Neurosci. |
pmid:21187849
|
Bari M et al. |
The manifold actions of endocannabinoids on female and male reproductive events. |
2011 |
Front Biosci (Landmark Ed) |
pmid:21196184
|
Guindon J et al. |
Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. |
2011 |
Br. J. Pharmacol. |
pmid:21198549
|
Liao YS et al. |
[Anandamide inhibits the growth of colorectal cancer cells through CB1 and lipid rafts]. |
2011 |
Zhonghua Zhong Liu Za Zhi |
pmid:21575494
|
Shekhar C |
Mixed signals: cannabinoid system offers new therapeutic possibilities as well as challenges. |
2011 |
Chem. Biol. |
pmid:21609833
|
Umathe SN et al. |
Involvement of endocannabinoids in antidepressant and anti-compulsive effect of fluoxetine in mice. |
2011 |
Behav. Brain Res. |
pmid:21549765
|
Arias-Carrión O et al. |
Biochemical modulation of the sleep-wake cycle: endogenous sleep-inducing factors. |
2011 |
J. Neurosci. Res. |
pmid:21557294
|
Sordelli MS et al. |
The effect of anandamide on uterine nitric oxide synthase activity depends on the presence of the blastocyst. |
2011 |
PLoS ONE |
pmid:21559512
|
Engel MA et al. |
Inhibitory CB1 and activating/desensitizing TRPV1-mediated cannabinoid actions on CGRP release in rodent skin. |
2011 |
Neuropeptides |
pmid:21514666
|
Hutchins HL et al. |
Eicosapentaenoic acid decreases expression of anandamide synthesis enzyme and cannabinoid receptor 2 in osteoblast-like cells. |
2011 |
J. Nutr. Biochem. |
pmid:20951563
|
Gervasi MG et al. |
Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation. |
2011 |
PLoS ONE |
pmid:21347292
|
Quercioli A et al. |
Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity. |
2011 |
Eur. Heart J. |
pmid:21303779
|
Correa F et al. |
The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells. |
2011 |
Brain Behav. Immun. |
pmid:21310228
|
Latek D et al. |
Modeling of ligand binding to G protein coupled receptors: cannabinoid CB1, CB2 and adrenergic β 2 AR. |
2011 |
J Mol Model |
pmid:21365223
|
Signorello MG et al. |
The anandamide effect on NO/cGMP pathway in human platelets. |
2011 |
J. Cell. Biochem. |
pmid:21328466
|
Greco R et al. |
Effects of anandamide in migraine: data from an animal model. |
2011 |
J Headache Pain |
pmid:21331757
|
Cippitelli A et al. |
Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. |
2011 |
PLoS ONE |
pmid:22140525
|
Taylor AH et al. |
Modulation of the endocannabinoid system in viable and non-viable first trimester pregnancies by pregnancy-related hormones. |
2011 |
Reprod. Biol. Endocrinol. |
pmid:22126420
|
Brizzi A et al. |
Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor. |
2011 |
J. Med. Chem. |
pmid:22044209
|
Hamtiaux L et al. |
Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism. |
2011 |
PLoS ONE |
pmid:22046372
|
Lin QS et al. |
Hippocampal endocannabinoids play an important role in induction of long-term potentiation and regulation of contextual fear memory formation. |
2011 |
Brain Res. Bull. |
pmid:21801815
|
Tsuboi K et al. |
Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways. |
2011 |
Biochim. Biophys. Acta |
pmid:21801852
|
Chianese R et al. |
Anandamide modulates the expression of GnRH-II and GnRHRs in frog, Rana esculenta, diencephalon. |
2011 |
Gen. Comp. Endocrinol. |
pmid:21802420
|
Clugston RD et al. |
Altered hepatic lipid metabolism in C57BL/6 mice fed alcohol: a targeted lipidomic and gene expression study. |
2011 |
J. Lipid Res. |
pmid:21856784
|
Dollery C |
Investigative clinical pharmacology. |
2011 |
Clin. Pharmacol. Ther. |
pmid:21862965
|
Mestre L et al. |
Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB(1) receptors. |
2011 |
J Neuroinflammation |
pmid:21851608
|
Feledziak M et al. |
SAR and LC/MS studies of β-lactamic inhibitors of human fatty acid amide hydrolase (hFAAH): evidence of a nonhydrolytic process. |
2011 |
J. Med. Chem. |
pmid:21899370
|
Palermo G et al. |
Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas. |
2011 |
J. Med. Chem. |
pmid:21830831
|
Zoerner AA et al. |
Allergen challenge increases anandamide in bronchoalveolar fluid of patients with allergic asthma. |
2011 |
Clin. Pharmacol. Ther. |
pmid:21716266
|
Brailoiu GC et al. |
Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide. |
2011 |
J. Biol. Chem. |
pmid:21719698
|
Catanzaro G et al. |
Effect of capacitation on the endocannabinoid system of mouse sperm. |
2011 |
Mol. Cell. Endocrinol. |
pmid:21723369
|