Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Hypertension, Portal D006975 12 associated lipids
Hypotension D007022 41 associated lipids
Hypothermia D007035 19 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Learning Disorders D007859 11 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Melanoma D008545 69 associated lipids
Memory Disorders D008569 33 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Marco EM et al. Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. 2009 Brain Res. pmid:19133243
McGregor IS et al. A comparison of delta 9-THC and anandamide induced c-fos expression in the rat forebrain. 1998 Brain Res. pmid:9748483
Murillo-Rodríguez E et al. Anandamide modulates sleep and memory in rats. 1998 Brain Res. pmid:9813364
Christopoulos A and Wilson K Interaction of anandamide with the M(1) and M(4) muscarinic acetylcholine receptors. 2001 Brain Res. pmid:11578621
González S et al. Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. 2002 Brain Res. pmid:12393235
Yue HY et al. AM404 enhances the spontaneous release of L-glutamate in a manner sensitive to capsazepine in adult rat substantia gelatinosa neurones. 2004 Brain Res. pmid:15276889
Barros DM et al. Interactions between anandamide-induced anterograde amnesia and post-training memory modulatory systems. 2004 Brain Res. pmid:15234253
Nicholson RA et al. Sodium channel inhibition by anandamide and synthetic cannabimimetics in brain. 2003 Brain Res. pmid:12834914
Prevot V et al. Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: neurovascular regulation. 1998 Brain Res. pmid:9593913
Stefano GB et al. Anandamide amidase inhibition enhances anandamide-stimulated nitric oxide release in invertebrate neural tissues. 1998 Brain Res. pmid:9630717
Van der Kloot W Anandamide, a naturally-occurring agonist of the cannabinoid receptor, blocks adenylate cyclase at the frog neuromuscular junction. 1994 Brain Res. pmid:7953630
Hohmann AG et al. Pre- and postsynaptic distribution of cannabinoid and mu opioid receptors in rat spinal cord. 1999 Brain Res. pmid:10082879
Lees G and Dougalis A Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro. 2004 Brain Res. pmid:14715144
Soni N et al. Anandamide and 2-AG are endogenously present within the laterodorsal tegmental nucleus: Functional implications for a role of eCBs in arousal. 2017 Brain Res. pmid:28404451
Lara-Celador I et al. Endocannabinoids reduce cerebral damage after hypoxic-ischemic injury in perinatal rats. 2012 Brain Res. pmid:22841538
Hoot MR et al. Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice. 2010 Brain Res. pmid:20380816
Fride E Anandamides: tolerance and cross-tolerance to delta 9-tetrahydrocannabinol. 1995 Brain Res. pmid:8593598
Minowa S et al. Capsaicin- and anandamide-induced gastric acid secretion via vanilloid receptor type 1 (TRPV1) in rat brain. 2005 Brain Res. pmid:15781048
Stefano GB et al. Identification and characterization of the leech CNS cannabinoid receptor: coupling to nitric oxide release. 1997 Brain Res. pmid:9125406
Potenzieri C et al. Excitation of cutaneous C nociceptors by intraplantar administration of anandamide. 2009 Brain Res. pmid:19285051
Romero J et al. Time-course of the effects of anandamide, the putative endogenous cannabinoid receptor ligand, on extrapyramidal function. 1995 Brain Res. pmid:8974649
Chakrabarti A et al. Neurobehavioral effects of anandamide and cannabinoid receptor gene expression in mice. 1998 Brain Res. Bull. pmid:9434204
Lin QS et al. Hippocampal endocannabinoids play an important role in induction of long-term potentiation and regulation of contextual fear memory formation. 2011 Brain Res. Bull. pmid:21801815
Fride E and Mechoulam R Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice. 1996 Brain Res. Dev. Brain Res. pmid:8873985
Matias I et al. Evidence for an endocannabinoid system in the central nervous system of the leech Hirudo medicinalis. 2001 Brain Res. Mol. Brain Res. pmid:11245916
Golech SA et al. Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors. 2004 Brain Res. Mol. Brain Res. pmid:15548432
Romero J et al. Fatty acid amide hydrolase localization in the human central nervous system: an immunohistochemical study. 2002 Brain Res. Mol. Brain Res. pmid:12008024
Yusifzade K et al. The protective role of anandamide in mesenteric ischemia reperfusion injury in guinea pig. 2009 Bratisl Lek Listy pmid:19711821
Fernandez-Solari J et al. Anandamide injected into the lateral ventricle of the brain inhibits submandibular salivary secretion by attenuating parasympathetic neurotransmission. 2009 Braz. J. Med. Biol. Res. pmid:19448903
Ribeiro A et al. Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests. 2009 Braz. J. Med. Biol. Res. pmid:19448906
Fogaça MV et al. Fine-tuning of defensive behaviors in the dorsal periaqueductal gray by atypical neurotransmitters. 2012 Braz. J. Med. Biol. Res. pmid:22392189
Kukushkin ML et al. Role of cannabinoid receptor agonists in mechanisms of suppression of central pain syndrome. 2006 Bull. Exp. Biol. Med. pmid:17369898
Krylatov AV et al. Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism. 2002 Bull. Exp. Biol. Med. pmid:12428277
Andrianova EL et al. In vitro effects of anandamide and prostamide e2 on normal and transformed nerve cells. 2011 Bull. Exp. Biol. Med. pmid:22442796
Ugdyzhekova DS et al. Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors. 2001 Bull. Exp. Biol. Med. pmid:11427912
Vavilin VA et al. Cytochrome P450 4F2 polymorphism in patients with liver cirrhosis. 2013 Bull. Exp. Biol. Med. pmid:24319743
Vásquez C et al. Effects of cannabinoids on endogenous K+ and Ca2+ currents in HEK293 cells. 2003 Can. J. Physiol. Pharmacol. pmid:12774849
Joseph J et al. Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. 2004 Cancer Immunol. Immunother. pmid:15034673
Blázquez C et al. Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. 2004 Cancer Res. pmid:15313899
Hiley CR and Hoi PM Oleamide: a fatty acid amide signaling molecule in the cardiovascular system? 2007 Cardiovasc Drug Rev pmid:17445087
Mukhopadhyay S and Tulis DA Endocannabinoid regulation of matrix metalloproteinases: implications in ischemic stroke. 2007 Cardiovasc Hematol Agents Med Chem pmid:17979695
Wang Y and Wang DH Neural control of blood pressure: focusing on capsaicin-sensitive sensory nerves. 2007 Cardiovasc Hematol Disord Drug Targets pmid:17346127
Mukhopadhyay P et al. CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes. 2010 Cardiovasc. Res. pmid:19942623
Barana A et al. Endocannabinoids and cannabinoid analogues block cardiac hKv1.5 channels in a cannabinoid receptor-independent manner. 2010 Cardiovasc. Res. pmid:19689982
Jiang LS et al. Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages. 2009 Cardiovasc. Res. pmid:19074161
Kvasnicka T [Endocannabinoids--the new option in the treatment of metabolic syndrome and in smoking cessation]. 2005 Cas. Lek. Cesk. pmid:15807291
Lozovaya N et al. Dual modulation of CNS voltage-gated calcium channels by cannabinoids: Focus on CB1 receptor-independent effects. 2009 Cell Calcium pmid:19682741
Tsumura M et al. TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts. 2012 Cell Calcium pmid:22656960
Juan-Picó P et al. Cannabinoid receptors regulate Ca(2+) signals and insulin secretion in pancreatic beta-cell. 2006 Cell Calcium pmid:16321437
Al Kury LT et al. Effects of endogenous cannabinoid anandamide on excitation-contraction coupling in rat ventricular myocytes. 2014 Cell Calcium pmid:24472666