Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Hypertension, Portal D006975 12 associated lipids
Hypotension D007022 41 associated lipids
Hypothermia D007035 19 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Learning Disorders D007859 11 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Melanoma D008545 69 associated lipids
Memory Disorders D008569 33 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Bisogno T et al. Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation. 1998 Eur. J. Biochem. pmid:9688276
Van Der Stelt M and Di Marzo V Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels. 2004 Eur. J. Biochem. pmid:15128293
MacCarrone M et al. Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor. 2001 Eur. J. Biochem. pmid:11168423
Fasia L et al. Uptake and metabolism of [3H]anandamide by rabbit platelets. Lack of transporter? 2003 Eur. J. Biochem. pmid:12919314
Bisogno T et al. The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors. 2001 Eur. J. Biochem. pmid:11277920
Salzet M et al. Comparative biology of the endocannabinoid system possible role in the immune response. 2000 Eur. J. Biochem. pmid:10931174
Sugiura T et al. Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine. 1996 Eur. J. Biochem. pmid:8797835
Matias I et al. Presence and regulation of the endocannabinoid system in human dendritic cells. 2002 Eur. J. Biochem. pmid:12153574
Kapoor S Modulation of intracellular pathways by anandamide and its evolving role in oncology. 2013 Eur. J. Cancer pmid:23434147
Laezza C et al. Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells. 2013 Eur. J. Cancer pmid:23434151
Rossi C et al. Endocannabinoids in platelets of chronic migraine patients and medication-overuse headache patients: relation with serotonin levels. 2008 Eur. J. Clin. Pharmacol. pmid:18004553
Di Marzo V et al. Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects. 2009 Eur. J. Endocrinol. pmid:19745037
Adermark L et al. Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activity. 2009 Eur. J. Neurosci. pmid:19120438
Millns PJ et al. Effects of inhibition of fatty acid amide hydrolase vs. the anandamide membrane transporter on TRPV1-mediated calcium responses in adult DRG neurons; the role of CB receptors. 2006 Eur. J. Neurosci. pmid:17229097
Sharkey KA et al. Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret. 2007 Eur. J. Neurosci. pmid:17459108
Ryan D et al. Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. 2007 Eur. J. Neurosci. pmid:17419758
Ahluwalia J et al. Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro. 2003 Eur. J. Neurosci. pmid:12823468
Sagan S et al. Anandamide and WIN 55212-2 inhibit cyclic AMP formation through G-protein-coupled receptors distinct from CB1 cannabinoid receptors in cultured astrocytes. 1999 Eur. J. Neurosci. pmid:10051770
Cippitelli A et al. The anandamide transport inhibitor AM404 reduces ethanol self-administration. 2007 Eur. J. Neurosci. pmid:17650118
Ali AB and Todorova M Asynchronous release of GABA via tonic cannabinoid receptor activation at identified interneuron synapses in rat CA1. 2010 Eur. J. Neurosci. pmid:20345910
Lemak MS et al. Cannabinoid regulation in identified synapse of terrestrial snail. 2007 Eur. J. Neurosci. pmid:18028114
Béquet F et al. CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus. 2007 Eur. J. Neurosci. pmid:18052990
Rivera P et al. Diet-dependent modulation of hippocampal expression of endocannabinoid signaling-related proteins in cannabinoid antagonist-treated obese rats. 2013 Eur. J. Neurosci. pmid:23033907
Sousa-Valente J et al. Anandamide in primary sensory neurons: too much of a good thing? 2014 Eur. J. Neurosci. pmid:24494681
Rea K et al. Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state. 2014 Eur. J. Neurosci. pmid:24494683
Maccarrone M et al. Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour. 2002 Eur. J. Neurosci. pmid:11982628
Peroni RN et al. Sex-linked differences in the vasorelaxant effects of anandamide in vascular mesenteric beds: role of oestrogens. 2004 Eur. J. Pharmacol. pmid:15189776
Vann RE et al. Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. 2009 Eur. J. Pharmacol. pmid:19470387
Ralevic V et al. Cannabinoid activation of recombinant and endogenous vanilloid receptors. 2001 Eur. J. Pharmacol. pmid:11672565
O'Sullivan SE et al. Vascular effects of delta 9-tetrahydrocannabinol (THC), anandamide and N-arachidonoyldopamine (NADA) in the rat isolated aorta. 2005 Eur. J. Pharmacol. pmid:15659311
Del Arco I et al. Attenuation of spontaneous opiate withdrawal in mice by the anandamide transport inhibitor AM404. 2002 Eur. J. Pharmacol. pmid:12409011
Wheal AJ et al. Hydrogen peroxide as a mediator of vasorelaxation evoked by N-oleoylethanolamine and anandamide in rat small mesenteric arteries. 2012 Eur. J. Pharmacol. pmid:22154756
Bouaboula M et al. Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation. 2005 Eur. J. Pharmacol. pmid:15987634
Wiley JL et al. Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents. 2014 Eur. J. Pharmacol. pmid:24858366
Mendizábal VE et al. Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed. 2001 Eur. J. Pharmacol. pmid:11567656
García Mdel C et al. Role of CGRP and GABA in the hypotensive effect of intrathecally administered anandamide to anesthetized rats. 2006 Eur. J. Pharmacol. pmid:16472800
Wickens AP and Pertwee RG delta 9-Tetrahydrocannabinol and anandamide enhance the ability of muscimol to induce catalepsy in the globus pallidus of rats. 1993 Eur. J. Pharmacol. pmid:8119321
Jackson SN et al. Volatile anesthetics and endogenous cannabinoid anandamide have additive and independent inhibitory effects on alpha(7)-nicotinic acetylcholine receptor-mediated responses in Xenopus oocytes. 2008 Eur. J. Pharmacol. pmid:18242598
Stamer WD et al. Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues. 2001 Eur. J. Pharmacol. pmid:11730719
Costa B and Colleoni M Changes in rat brain energetic metabolism after exposure to anandamide or Delta(9)-tetrahydrocannabinol. 2000 Eur. J. Pharmacol. pmid:10781666
Alptekin A et al. The effects of anandamide transport inhibitor AM404 on voltage-dependent calcium channels. 2010 Eur. J. Pharmacol. pmid:20171208
Marichal-Cancino BA et al. Analysis of anandamide- and lysophosphatidylinositol-induced inhibition of the vasopressor responses produced by sympathetic stimulation or noradrenaline in pithed rats. 2013 Eur. J. Pharmacol. pmid:24076186
Adinolfi B et al. Anticancer activity of anandamide in human cutaneous melanoma cells. 2013 Eur. J. Pharmacol. pmid:24041928
Martin BR et al. Assessment of structural commonality between tetrahydrocannabinol and anandamide. 2002 Eur. J. Pharmacol. pmid:11790376
Fride E et al. Critical role of the endogenous cannabinoid system in mouse pup suckling and growth. 2001 Eur. J. Pharmacol. pmid:11426843
Someya A et al. Arachidonic acid release and prostaglandin F(2alpha) formation induced by anandamide and capsaicin in PC12 cells. 2002 Eur. J. Pharmacol. pmid:12206851
Sprague J et al. Temperature-dependent activation of recombinant rat vanilloid VR1 receptors expressed in HEK293 cells by capsaicin and anandamide. 2001 Eur. J. Pharmacol. pmid:11448475
Rácz I et al. Anandamide effects on 5-HT(3) receptors in vivo. 2008 Eur. J. Pharmacol. pmid:18775693
Wiley JL et al. Evaluation of cannabimimetic effects of structural analogs of anandamide in rats. 1998 Eur. J. Pharmacol. pmid:9760024
Berdyshev EV et al. Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells. 1997 Eur. J. Pharmacol. pmid:9253958