Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Weight Gain D015430 101 associated lipids
Ocular Hypotension D015814 2 associated lipids
Alveolar Bone Loss D016301 10 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Impotence, Vasculogenic D018783 4 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Endotoxemia D019446 27 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Somatosensory Disorders D020886 1 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Akinshola BE et al. Anandamide inhibition of recombinant AMPA receptor subunits in Xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP. 1999 Naunyn Schmiedebergs Arch. Pharmacol. pmid:10543424
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Mallet PE and Beninger RJ Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. 1998 Life Sci. pmid:9651110
De Petrocellis L et al. The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9653194
Berdyshev E et al. Effects of cannabinoid receptor ligands on LPS-induced pulmonary inflammation in mice. 1998 Life Sci. pmid:9718090
Jaggar SI et al. The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. 1998 Pain pmid:9696473
Bisogno T et al. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. 1998 Biochem. Biophys. Res. Commun. pmid:9703957
Kondo S et al. Accumulation of various N-acylethanolamines including N-arachidonoylethanolamine (anandamide) in cadmium chloride-administered rat testis. 1998 Arch. Biochem. Biophys. pmid:9637740
Stefano GB et al. Antagonism of LPS and IFN-gamma induction of iNOS in human saphenous vein endothelium by morphine and anandamide by nitric oxide inhibition of adenylate cyclase. 1998 J. Cardiovasc. Pharmacol. pmid:9641464
Stefano GB et al. Long-term exposure of human blood vessels to HIV gp120, morphine, and anandamide increases endothelial adhesion of monocytes: uncoupling of nitric oxide release. 1998 J. Cardiovasc. Pharmacol. pmid:9641470
Mallet PE and Beninger RJ The cannabinoid CB1 receptor antagonist SR141716A attenuates the memory impairment produced by delta9-tetrahydrocannabinol or anandamide. 1998 Psychopharmacology (Berl.) pmid:9862397
Stahl SM Getting stoned without inhaling: anandamide is the brain's natural marijuana. 1998 J Clin Psychiatry pmid:9862600
Bonhaus DW et al. Dual activation and inhibition of adenylyl cyclase by cannabinoid receptor agonists: evidence for agonist-specific trafficking of intracellular responses. 1998 J. Pharmacol. Exp. Ther. pmid:9864268
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Derocq JM et al. The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor-independent pathway in hematopoietic cell lines. 1998 FEBS Lett. pmid:9563506
Wiley JL et al. Evaluation of cannabimimetic effects of structural analogs of anandamide in rats. 1998 Eur. J. Pharmacol. pmid:9760024
Axelrod J and Felder CC Cannabinoid receptors and their endogenous agonist, anandamide. 1998 Neurochem. Res. pmid:9566594
Lichtman AH et al. Effects of SR 141716A after acute or chronic cannabinoid administration in dogs. 1998 Eur. J. Pharmacol. pmid:9797029
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Di Marzo V et al. Interactions between synthetic vanilloids and the endogenous cannabinoid system. 1998 FEBS Lett. pmid:9801167
Van der Kloot W et al. Calcitonin gene-related peptide acts presynaptically to increase quantal size and output at frog neuromuscular junctions. 1998 J. Physiol. (Lond.) pmid:9508830
Stein EA et al. Selective effects of the endogenous cannabinoid arachidonylethanolamide (anandamide) on regional cerebral blood flow in the rat. 1998 Neuropsychopharmacology pmid:9803424
Di Marzo V et al. The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide. 1998 Biochem. J. pmid:9512456
Randall MD and Kendall DA Anandamide and endothelium-derived hyperpolarizing factor act via a common vasorelaxant mechanism in rat mesentery. 1998 Eur. J. Pharmacol. pmid:9617751
Edgemond WS et al. Human platelets and polymorphonuclear leukocytes synthesize oxygenated derivatives of arachidonylethanolamide (anandamide): their affinities for cannabinoid receptors and pathways of inactivation. 1998 Mol. Pharmacol. pmid:9658204
Tong W et al. Derivation of a pharmacophore model for anandamide using constrained conformational searching and comparative molecular field analysis. 1998 J. Med. Chem. pmid:9784095
Richardson JD et al. Antihyperalgesic effects of spinal cannabinoids. 1998 Eur. J. Pharmacol. pmid:9600630