Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Goparaju SK et al. | Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand. | 1998 | FEBS Lett. | pmid:9475172 |
Hampson AJ et al. | Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission. | 1998 | J. Neurochem. | pmid:9453561 |
Sulcova E et al. | Biphasic effects of anandamide. | 1998 | Pharmacol. Biochem. Behav. | pmid:9476980 |
Kimura T et al. | Anandamide, an endogenous cannabinoid receptor ligand, also interacts with 5-hydroxytryptamine (5-HT) receptor. | 1998 | Biol. Pharm. Bull. | pmid:9556149 |
Pratt PF et al. | N-arachidonylethanolamide relaxation of bovine coronary artery is not mediated by CB1 cannabinoid receptor. | 1998 | Am. J. Physiol. | pmid:9458889 |
Richardson JD et al. | Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. | 1998 | Pain | pmid:9539680 |
Mikawa Y et al. | Ocular activity of topically administered anandamide in the rabbit. | 1997 Jul-Aug | Jpn. J. Ophthalmol. | pmid:9304433 |
Hunter SA and Burstein SH | Receptor mediation in cannabinoid stimulated arachidonic acid mobilization and anandamide synthesis. | 1997 | Life Sci. | pmid:9126878 |
Di Tomaso E et al. | Endogenous lipids that activate cannabinoid receptors. Formation and inactivation. | 1997 | Adv. Exp. Med. Biol. | pmid:9321973 |
White R and Hiley CR | A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. | 1997 | Br. J. Pharmacol. | pmid:9422801 |
Zygmunt PM et al. | Studies on the effects of anandamide in rat hepatic artery. | 1997 | Br. J. Pharmacol. | pmid:9422814 |
Jarrahian A and Hillard CJ | Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9431821 |
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Bloom AS et al. | Nonclassical and endogenous cannabinoids: effects on the ordering of brain membranes. | 1997 | Neurochem. Res. | pmid:9131634 |
Wenger T et al. | Effects of anandamide on gestation in pregnant rats. | 1997 | Life Sci. | pmid:9199480 |
Molina-Holgado F et al. | Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes. | 1997 | Neuroreport | pmid:9223079 |
Willoughby KA et al. | The biodisposition and metabolism of anandamide in mice. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9223560 |
Beltramo M et al. | Inhibition of anandamide hydrolysis in rat brain tissue by (E)-6-(bromomethylene) tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one. | 1997 | FEBS Lett. | pmid:9091314 |
Thumser AE et al. | A fluorescence displacement assay for the measurement of arachidonoyl ethanolamide (anandamide) and oleoyl amide (octadecenoamide) hydrolysis. | 1997 | Biochem. Pharmacol. | pmid:9065749 |
Sheskin T et al. | Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor. | 1997 | J. Med. Chem. | pmid:9057852 |
Fowler CJ et al. | Ibuprofen inhibits rat brain deamidation of anandamide at pharmacologically relevant concentrations. Mode of inhibition and structure-activity relationship. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9353392 |
Stark S et al. | Binding of aminoalkylindoles to noncannabinoid binding sites in NG108-15 cells. | 1997 | Cell. Mol. Neurobiol. | pmid:9353590 |
van der Stelt M et al. | The effect of hydroxylation of linoleoyl amides on their cannabinomimetic properties. | 1997 | FEBS Lett. | pmid:9357990 |
Beltramo M et al. | Functional role of high-affinity anandamide transport, as revealed by selective inhibition. | 1997 | Science | pmid:9262477 |
Fernández-Ruiz JJ et al. | Time course of the effects of different cannabimimetics on prolactin and gonadotrophin secretion: evidence for the presence of CB1 receptors in hypothalamic structures and their involvement in the effects of cannabimimetics. | 1997 | Biochem. Pharmacol. | pmid:9256167 |