Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Neuralgia D009437 28 associated lipids
Fibromyalgia D005356 4 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Mycoses D009181 18 associated lipids
Bulimia D002032 3 associated lipids
Sleep Deprivation D012892 5 associated lipids
Urinary Incontinence D014549 4 associated lipids
Vascular System Injuries D057772 2 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Pregnancy, Ectopic D011271 5 associated lipids
Ocular Hypotension D015814 2 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Impotence, Vasculogenic D018783 4 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Somatosensory Disorders D020886 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
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Authors Title Published Journal PubMed Link
Smith M et al. The Effects of the Endocannabinoids Anandamide and 2-Arachidonoylglycerol on Human Osteoblast Proliferation and Differentiation. 2015 PLoS ONE pmid:26414859
Gouveia-Figueira S et al. Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor. 2015 PLoS ONE pmid:26406890
Thörn Pérez C et al. Substance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels. 2015 PLoS ONE pmid:26197458
Chon SH et al. Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity. 2012 PLoS ONE pmid:22937137
De Angelis V et al. Endocannabinoids control platelet activation and limit aggregate formation under flow. 2014 PLoS ONE pmid:25264625
Di Pasquale E et al. The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependent. 2009 PLoS ONE pmid:19330032
Leo LM et al. Age-dependent relevance of endogenous 5-lipoxygenase derivatives in anxiety-like behavior in mice. 2014 PLoS ONE pmid:24416334
Compagnucci C et al. Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells. 2013 PLoS ONE pmid:23372698
Bhaskaran MD and Smith BN Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy. 2010 PLoS ONE pmid:20498848
Chadwick W et al. Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. 2010 PLoS ONE pmid:21179406
Ligresti A et al. Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter. 2010 PLoS ONE pmid:20422025
Pava MJ et al. Endocannabinoid modulation of cortical up-states and NREM sleep. 2014 PLoS ONE pmid:24520411
Murtaza G et al. TASK-1 potassium channel is not critically involved in mediating hypoxic pulmonary vasoconstriction of murine intra-pulmonary arteries. 2017 PLoS ONE pmid:28301582
Kwolek G et al. [Influence of anandamide, the endogenous agonist of cannabinoid receptors on the circulatory system]. 2005 Postepy Hig Med Dosw (Online) pmid:15928605
Pertwee RG Elevating endocannabinoid levels: pharmacological strategies and potential therapeutic applications. 2014 Proc Nutr Soc pmid:24135210
Burston JJ and Woodhams SG Endocannabinoid system and pain: an introduction. 2014 Proc Nutr Soc pmid:24148358
Brown WH et al. Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22912404
Adermark L and Lovinger DM Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:18077376
Das SK et al. Cannabinoid ligand-receptor signaling in the mouse uterus. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7753807
Mukhopadhyay B et al. Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21383171