| MeSH term | MeSH ID | Detail |
|---|---|---|
| Seizures | D012640 | 87 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Peptic Ulcer | D010437 | 19 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Ischemic Attack, Transient | D002546 | 42 associated lipids |
| Substance-Related Disorders | D019966 | 2 associated lipids |
| Hepatitis | D006505 | 11 associated lipids |
| Hyperalgesia | D006930 | 42 associated lipids |
| Spinal Cord Injuries | D013119 | 34 associated lipids |
| Brain Damage, Chronic | D001925 | 6 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Harris J et al. | Spinal anandamide inhibits nociceptive transmission via cannabinoid receptor activation in vivo. | 2000 | Neuroreport | pmid:10976969 |
| Levin M and Mercola M | Expression of connexin 30 in Xenopus embryos and its involvement in hatching gland function. | 2000 | Dev. Dyn. | pmid:10974676 |
| Bannerman P et al. | Early migratory rat neural crest cells express functional gap junctions: evidence that neural crest cell survival requires gap junction function. | 2000 | J. Neurosci. Res. | pmid:10972957 |
| Van den Bossche I and Vanheel B | Influence of cannabinoids on the delayed rectifier in freshly dissociated smooth muscle cells of the rat aorta. | 2000 | Br. J. Pharmacol. | pmid:10960073 |
| Martin BR et al. | Cannabinoid properties of methylfluorophosphonate analogs. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10945879 |
| Okamoto H et al. | Sphingosine 1-phosphate stimulates G(i)- and Rho-mediated vascular endothelial cell spreading and migration. | 2000 | Thromb. Res. | pmid:10942792 |
| Salzet M et al. | Comparative biology of the endocannabinoid system possible role in the immune response. | 2000 | Eur. J. Biochem. | pmid:10931174 |
| Spicuzza L et al. | Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves. | 2000 | Br. J. Pharmacol. | pmid:10928980 |
| Maccarrone M et al. | Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors. | 2000 | J. Biol. Chem. | pmid:10913156 |
| Palmer SL et al. | Natural and synthetic endocannabinoids and their structure-activity relationships. | 2000 | Curr. Pharm. Des. | pmid:10903399 |
| Di Marzo T et al. | Endocannabinoids: new targets for drug development. | 2000 | Curr. Pharm. Des. | pmid:10903398 |
| Hansen HH et al. | Determination of the phospholipid precursor of anandamide and other N-acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons. | 2000 | J. Neurochem. | pmid:10899965 |
| Szöke E et al. | Interacting effects of capsaicin and anandamide on intracellular calcium in sensory neurones. | 2000 | Neuroreport | pmid:10884049 |
| Fichera M et al. | A 3D-QSAR study on the structural requirements for binding to CB(1) and CB(2) cannabinoid receptors. | 2000 | J. Med. Chem. | pmid:10882356 |
| Di Marzo V et al. | Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease. | 2000 | FASEB J. | pmid:10877836 |
| Andersson M et al. | Neurotoxicity of glutamate in chick telencephalon neurons: reduction of toxicity by preincubation with carbachol, but not by the endogenous fatty acid amides anandamide and palmitoylethanolamide. | 2000 | Arch. Toxicol. | pmid:10877002 |
| Tytgat J et al. | Cannabinoid mimics in chocolate utilized as an argument in court. | 2000 | Int. J. Legal Med. | pmid:10876983 |
| Song ZH and Zhong M | CB1 cannabinoid receptor-mediated cell migration. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10871313 |
| Hillard CJ | Endocannabinoids and vascular function. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10871291 |
| Hohmann AG and Herkenham M | Localization of cannabinoid CB(1) receptor mRNA in neuronal subpopulations of rat striatum: a double-label in situ hybridization study. | 2000 | Synapse | pmid:10842353 |
| Piomelli D et al. | The endocannabinoid system as a target for therapeutic drugs. | 2000 | Trends Pharmacol. Sci. | pmid:10838609 |
| Szolcsányi J | Anandamide and the question of its functional role for activation of capsaicin receptors. | 2000 | Trends Pharmacol. Sci. | pmid:10838604 |
| Zygmunt PM et al. | Differential actions of anandamide, potassium ions and endothelium-derived hyperpolarizing factor in guinea-pig basilar artery. | 2000 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10832608 |
| Zygmunt PM et al. | The anandamide transport inhibitor AM404 activates vanilloid receptors. | 2000 | Eur. J. Pharmacol. | pmid:10822052 |
| Davis JB et al. | Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. | 2000 | Nature | pmid:10821274 |
| Jarrahian A et al. | Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter. | 2000 | J. Neurochem. | pmid:10820223 |
| Beltramo M and Piomelli D | Carrier-mediated transport and enzymatic hydrolysis of the endogenous cannabinoid 2-arachidonylglycerol. | 2000 | Neuroreport | pmid:10817598 |
| Boger DL et al. | Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10805767 |
| Costa B et al. | Precipitated and spontaneous withdrawal in rats tolerant to anandamide. | 2000 | Psychopharmacology (Berl.) | pmid:10805606 |
| Yagen B and Burstein S | Novel and sensitive method for the detection of anandamide by the use of its dansyl derivative. | 2000 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10798298 |
| Maccarrone M et al. | Anandamide uptake by human endothelial cells and its regulation by nitric oxide. | 2000 | J. Biol. Chem. | pmid:10788462 |
| Hungund BL and Basavarajappa BS | Are anandamide and cannabinoid receptors involved in ethanol tolerance? A review of the evidence. | 2000 Mar-Apr | Alcohol Alcohol. | pmid:10787386 |
| Kunos G et al. | Cardiovascular effects of endocannabinoids--the plot thickens. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785543 |
| Di Marzo V et al. | Cannabimimetic fatty acid derivatives in cancer and inflammation. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785541 |
| Burstein SH et al. | Oxidative metabolism of anandamide. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785540 |
| Hillard CJ | Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785538 |
| Sarker KP et al. | Anandamide induces apoptosis of PC-12 cells: involvement of superoxide and caspase-3. | 2000 | FEBS Lett. | pmid:10781801 |
| Costa B and Colleoni M | Changes in rat brain energetic metabolism after exposure to anandamide or Delta(9)-tetrahydrocannabinol. | 2000 | Eur. J. Pharmacol. | pmid:10781666 |
| Castellano C et al. | Strain-dependent effects of anandamide on memory consolidation in mice are antagonized by naltrexone. | 1999 | Behav Pharmacol | pmid:10780251 |
| Gonsiorek W et al. | Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide. | 2000 | Mol. Pharmacol. | pmid:10779390 |
| Beltramo M et al. | Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitor. | 2000 | J. Neurosci. | pmid:10777802 |
| Maccarrone M et al. | Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage. | 2000 | Lancet | pmid:10776746 |
| Lockwood CJ | Prediction of pregnancy loss. | 2000 | Lancet | pmid:10776739 |
| Hao S et al. | Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice. | 2000 | Eur. J. Pharmacol. | pmid:10762668 |
| Braud S et al. | Activation of rabbit blood platelets by anandamide through its cleavage into arachidonic acid. | 2000 | FEBS Lett. | pmid:10760504 |
| Brăiloiu C et al. | [Endothelium-derived hyperpolarizing factor]. | 1998 Jul-Dec | Rev Med Chir Soc Med Nat Iasi | pmid:10756843 |
| Gómez del Pulgar T et al. | The CB1 cannabinoid receptor is coupled to the activation of protein kinase B/Akt. | 2000 | Biochem. J. | pmid:10749665 |
| Rajan S et al. | TASK-3, a novel tandem pore domain acid-sensitive K+ channel. An extracellular histiding as pH sensor. | 2000 | J. Biol. Chem. | pmid:10747866 |
| Markey SP et al. | Base- and acid-catalyzed interconversions of O-acyl- and N-acyl-ethanolamines: a cautionary note for lipid analyses. | 2000 | J. Lipid Res. | pmid:10744787 |
| Smart D and Jerman JC | Anandamide: an endogenous activator of the vanilloid receptor. | 2000 | Trends Pharmacol. Sci. | pmid:10740287 |
| Di Marzo V et al. | Enhancement of anandamide formation in the limbic forebrain and reduction of endocannabinoid contents in the striatum of delta9-tetrahydrocannabinol-tolerant rats. | 2000 | J. Neurochem. | pmid:10737621 |
| Wang Y et al. | Polymyxin B binds to anandamide and inhibits its cytotoxic effect. | 2000 | FEBS Lett. | pmid:10734225 |
| Muthian S et al. | Synthesis and characterization of a fluorescent substrate for the N-arachidonoylethanolamine (anandamide) transmembrane carrier. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10734181 |
| González S et al. | Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10733937 |
| Lay L et al. | Pharmacological characterisation of cannabinoid CB(1) receptors in the rat and mouse. | 2000 | Eur. J. Pharmacol. | pmid:10720647 |
| Oliveira L et al. | Effects of some isoprostanes on the human umbilical artery in vitro. | 2000 | Br. J. Pharmacol. | pmid:10711349 |
| Houser SJ et al. | Dynorphin B and spinal analgesia: induction of antinociception by the cannabinoids CP55,940, Delta(9)-THC and anandamide. | 2000 | Brain Res. | pmid:10700588 |
| Arai Y et al. | Sensitive determination of anandamide in rat brain utilizing a coupled-column HPLC with fluorimetric detection. | 2000 | Biomed. Chromatogr. | pmid:10694706 |
| Smart D et al. | The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1). | 2000 | Br. J. Pharmacol. | pmid:10694225 |
| Maccarrone M et al. | Human mast cells take up and hydrolyze anandamide under the control of 5-lipoxygenase and do not express cannabinoid receptors. | 2000 | FEBS Lett. | pmid:10692582 |
| Lagalwar S et al. | Anandamides inhibit binding to the muscarinic acetylcholine receptor. | 1999 Aug-Oct | J. Mol. Neurosci. | pmid:10691292 |
| Rakhshan F et al. | Carrier-mediated uptake of the endogenous cannabinoid anandamide in RBL-2H3 cells. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688610 |
| Griffin G et al. | Cloning and pharmacological characterization of the rat CB(2) cannabinoid receptor. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688601 |
| Tiger G et al. | Pharmacological properties of rat brain fatty acid amidohydrolase in different subcellular fractions using palmitoylethanolamide as substrate. | 2000 | Biochem. Pharmacol. | pmid:10677581 |
| Schmid PC et al. | A sensitive endocannabinoid assay. The simultaneous analysis of N-acylethanolamines and 2-monoacylglycerols. | 2000 | Chem. Phys. Lipids | pmid:10669310 |
| Zygmunt PM et al. | Anandamide - the other side of the coin. | 2000 | Trends Pharmacol. Sci. | pmid:10664604 |
| Sinor AD et al. | Endocannabinoids protect cerebral cortical neurons from in vitro ischemia in rats. | 2000 | Neurosci. Lett. | pmid:10653017 |
| Sugiura T et al. | Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells. | 2000 | J. Biol. Chem. | pmid:10617657 |
| Melck D et al. | Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation. | 2000 | Endocrinology | pmid:10614630 |
| Melck D et al. | Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells. | 1999 | FEBS Lett. | pmid:10606728 |
| Bisogno T et al. | Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina. | 1999 | Arch. Biochem. Biophys. | pmid:10577359 |
| Járai Z et al. | Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570211 |
| Gifford AN et al. | Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374). | 1999 | Eur. J. Pharmacol. | pmid:10556675 |
| Akinshola BE et al. | Anandamide inhibition of recombinant AMPA receptor subunits in Xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10543424 |
| Yousif MH and Oriowo MA | Inhibitory effects of cannabinoid receptor ligands on electrically-evoked responses in rat isolated tracheal ring segments. | 1999 | Pharmacol. Res. | pmid:10527656 |
| McAllister SD et al. | Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a xenopus oocyte expression system. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10525080 |
| Chaytor AT et al. | The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication. | 1999 | J. Physiol. (Lond.) | pmid:10523421 |
| Katayama K et al. | Equilibrium in the hydrolysis and synthesis of cannabimimetic anandamide demonstrated by a purified enzyme. | 1999 | Biochim. Biophys. Acta | pmid:10521704 |
| Walker JM et al. | Pain modulation by release of the endogenous cannabinoid anandamide. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10518599 |
| Wiley JL | Cannabis: discrimination of "internal bliss"? | 1999 | Pharmacol. Biochem. Behav. | pmid:10515300 |
| Kuwae T et al. | Biosynthesis and turnover of anandamide and other N-acylethanolamines in peritoneal macrophages. | 1999 | FEBS Lett. | pmid:10508930 |
| Leweke FM et al. | Elevated endogenous cannabinoids in schizophrenia. | 1999 | Neuroreport | pmid:10501554 |
| Molderings GJ et al. | Presynaptic cannabinoid and imidazoline receptors in the human heart and their potential relationship. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10494885 |
| Di Marzo V et al. | Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids. | 1999 | Curr. Med. Chem. | pmid:10469888 |
| Di Marzo V | Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators. | 1999 | Life Sci. | pmid:10462065 |
| Howlett AC et al. | Signal transduction of eicosanoid CB1 receptor ligands. | 1999 | Life Sci. | pmid:10462062 |
| Khanolkar AD and Makriyannis A | Structure-activity relationships of anandamide, an endogenous cannabinoid ligand. | 1999 | Life Sci. | pmid:10462061 |
| Martin BR et al. | Discovery and characterization of endogenous cannabinoids. | 1999 | Life Sci. | pmid:10462059 |
| Melck D et al. | Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10448105 |
| González S et al. | Extrapyramidal and neuroendocrine effects of AM404, an inhibitor of the carrier-mediated transport of anandamide. | 1999 | Life Sci. | pmid:10447218 |
| Zygmunt PM et al. | Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. | 1999 | Nature | pmid:10440374 |
| Ueda N et al. | An acid amidase hydrolyzing anandamide as an endogenous ligand for cannabinoid receptors. | 1999 | FEBS Lett. | pmid:10431820 |
| Hansen HS et al. | Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity. | 1999 | Lipids | pmid:10419193 |
| Di Marzo V et al. | Metabolism of anandamide and 2-arachidonoylglycerol: an historical overview and some recent developments. | 1999 | Lipids | pmid:10419192 |
| Zenor BN et al. | Endocrine and other responses to acute administration of cannabinoid compounds to non-stressed male calves. | 1999 | Life Sci. | pmid:10416818 |
| De Petrocellis L et al. | Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response. | 1999 | Neuroscience | pmid:10392859 |
| Ameri A et al. | Effects of the endogeneous cannabinoid, anandamide, on neuronal activity in rat hippocampal slices. | 1999 | Br. J. Pharmacol. | pmid:10372827 |
| Gebremedhin D et al. | Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current. | 1999 | Am. J. Physiol. | pmid:10362691 |
| Ng EW et al. | Unique analogues of anandamide: arachidonyl ethers and carbamates and norarachidonyl carbamates and ureas. | 1999 | J. Med. Chem. | pmid:10354405 |
| Fimiani C et al. | Morphine and anandamide stimulate intracellular calcium transients in human arterial endothelial cells: coupling to nitric oxide release. | 1999 | Cell. Signal. | pmid:10353693 |