| MeSH term | MeSH ID | Detail |
|---|---|---|
| Migraine Disorders | D008881 | 11 associated lipids |
| Morphine Dependence | D009021 | 9 associated lipids |
| Multiple Sclerosis | D009103 | 13 associated lipids |
| Muscle Spasticity | D009128 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Neoplasm Invasiveness | D009361 | 23 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bardell TK and Barker EL | Activation of TRPC6 channels promotes endocannabinoid biosynthesis in neuronal CAD cells. | 2010 | Neurochem. Int. | pmid:20466028 |
| Sang N et al. | Anandamide potentiation of miniature spontaneous excitatory synaptic transmission is mediated via IP3 pathway. | 2010 | Neurochem. Int. | pmid:20064571 |
| Molderings GJ et al. | Noradrenaline release-inhibiting receptors on PC12 cells devoid of alpha(2(-)) and CB(1) receptors: similarities to presynaptic imidazoline and edg receptors. | 2002 | Neurochem. Int. | pmid:11738482 |
| Navarro M and RodrÃguez de Fonseca F | The neurobiology of cannabinoid transmission: from anandamide signaling to higher cerebral functions and disease. | 1998 | Neurobiol. Dis. | pmid:9974172 |
| Di Marzo V and Deutsch DG | Biochemistry of the endogenous ligands of cannabinoid receptors. | 1998 | Neurobiol. Dis. | pmid:9974173 |
| Piomelli D et al. | Endogenous cannabinoid signaling. | 1998 | Neurobiol. Dis. | pmid:9974178 |
| Vázquez C et al. | Endocannabinoids regulate the activity of astrocytic hemichannels and the microglial response against an injury: In vivo studies. | 2015 | Neurobiol. Dis. | pmid:25917763 |
| Hawkins V and Butt A | TASK-1 channels in oligodendrocytes: a role in ischemia mediated disruption. | 2013 | Neurobiol. Dis. | pmid:23567653 |
| Garcia-Ovejero D et al. | The endocannabinoid system is modulated in response to spinal cord injury in rats. | 2009 | Neurobiol. Dis. | pmid:18930143 |
| Meuth SG et al. | The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice. | 2009 | Neurobiol. Dis. | pmid:18930826 |
| Khasabova IA et al. | Increased anandamide uptake by sensory neurons contributes to hyperalgesia in a model of cancer pain. | 2013 | Neurobiol. Dis. | pmid:23644187 |
| Cabranes A et al. | Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis. | 2005 | Neurobiol. Dis. | pmid:16242629 |
| Jung KM et al. | An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. | 2012 | Neurobiol. Aging | pmid:21546126 |
| Wise LE et al. | Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task. | 2009 | Neurobiol Learn Mem | pmid:19524055 |
| Munguba H et al. | Pre-training anandamide infusion within the basolateral amygdala impairs plus-maze discriminative avoidance task in rats. | 2011 | Neurobiol Learn Mem | pmid:21440651 |
| De Oliveira Alvares L et al. | Differential role of the hippocampal endocannabinoid system in the memory consolidation and retrieval mechanisms. | 2008 | Neurobiol Learn Mem | pmid:18342551 |
| Costanzi M et al. | Effects of anandamide and morphine combinations on memory consolidation in cd1 mice: involvement of dopaminergic mechanisms. | 2004 | Neurobiol Learn Mem | pmid:14990234 |
| Costanzi M et al. | Anandamide and memory in CD1 mice: effects of immobilization stress and of prior experience. | 2003 | Neurobiol Learn Mem | pmid:12676519 |
| Mechoulam R | The promise of advances in the field of endocannabinoids. | 2004 Feb-Apr | Neuro Endocrinol. Lett. | pmid:15159675 |
| Fride E | The endocannabinoid-CB receptor system: Importance for development and in pediatric disease. | 2004 Feb-Apr | Neuro Endocrinol. Lett. | pmid:15159678 |
| Russo EB | Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? | 2004 Feb-Apr | Neuro Endocrinol. Lett. | pmid:15159679 |
| Malek N et al. | Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures. | 2015 | Neural Plast. | pmid:26090232 |
| Crozier Willi G et al. | Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods. | 2001 | Nestle Nutr Workshop Ser Clin Perform Programme | pmid:11510437 |
| Barthó L et al. | Nitric oxide is involved in the relaxant effect of capsaicin in the human sigmoid colon circular muscle. | 2002 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:12382081 |
| Holt S and Fowler CJ | Anandamide metabolism by fatty acid amide hydrolase in intact C6 glioma cells. Increased sensitivity to inhibition by ibuprofen and flurbiprofen upon reduction of extra- but not intracellular pH. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:12644895 |
| Schulte K et al. | Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor. | 2012 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:22215206 |
| del Carmen GarcÃa M et al. | Hypotensive effect of anandamide through the activation of CB1 and VR1 spinal receptors in urethane-anesthetized rats. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:14504685 |
| Baranowska-Kuczko M et al. | Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries. | 2014 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:24682422 |
| Molderings GJ et al. | Presynaptic cannabinoid and imidazoline receptors in the human heart and their potential relationship. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10494885 |
| Akinshola BE et al. | Anandamide inhibition of recombinant AMPA receptor subunits in Xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10543424 |
| Fisar Z | Inhibition of monoamine oxidase activity by cannabinoids. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20401651 |
| Malinowska B et al. | Involvement of central beta2-adrenergic, NMDA and thromboxane A2 receptors in the pressor effect of anandamide in rats. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20198363 |
| Terranova JP et al. | Inhibition of long-term potentiation in rat hippocampal slices by anandamide and WIN55212-2: reversal by SR141716 A, a selective antagonist of CB1 cannabinoid receptors. | 1995 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:8751088 |
| Zygmunt PM et al. | Differential actions of anandamide, potassium ions and endothelium-derived hyperpolarizing factor in guinea-pig basilar artery. | 2000 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10832608 |
| Ilayan E et al. | Do cannabinoids exhibit a tyramine-like effect? | 2013 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:23900610 |
| Avelino A and Cruz F | TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications. | 2006 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:16721555 |
| Jergas B et al. | O-2050 facilitates noradrenaline release and increases the CB1 receptor inverse agonistic effect of rimonabant in the guinea pig hippocampus. | 2014 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:24853577 |
| Steffens M et al. | Quantitative measurement of depolarization-induced anandamide release in human and rat neocortex. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:14566450 |
| Kracke GR et al. | The cannabinoid receptor agonists, anandamide and WIN 55,212-2, do not directly affect mu opioid receptors expressed in Xenopus oocytes. | 2007 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:17960365 |
| Mechoulam R et al. | Anandamide may mediate sleep induction. | 1997 | Nature | pmid:9288961 |
| Hohmann AG et al. | An endocannabinoid mechanism for stress-induced analgesia. | 2005 | Nature | pmid:15973410 |
| Iversen L | Pharmacology. Endogenous cannabinoids. | 1994 | Nature | pmid:7990950 |
| Calignano A et al. | Control of pain initiation by endogenous cannabinoids. | 1998 | Nature | pmid:9685157 |
| Zygmunt PM et al. | Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. | 1999 | Nature | pmid:10440374 |
| Munro S et al. | Molecular characterization of a peripheral receptor for cannabinoids. | 1993 | Nature | pmid:7689702 |
| Premkumar LS and Ahern GP | Induction of vanilloid receptor channel activity by protein kinase C. | 2000 Dec 21-28 | Nature | pmid:11140687 |
| Davis JB et al. | Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. | 2000 | Nature | pmid:10821274 |
| Venance L et al. | Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes. | 1995 | Nature | pmid:7637807 |
| Watanabe H et al. | Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. | 2003 | Nature | pmid:12879072 |
| Mechoulam R and Fride E | Physiology. A hunger for cannabinoids. | 2001 | Nature | pmid:11298428 |