Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Migraine Disorders D008881 11 associated lipids
Morphine Dependence D009021 9 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Muscle Spasticity D009128 5 associated lipids
Mycoses D009181 18 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Neoplasms D009369 13 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Nerve Degeneration D009410 53 associated lipids
Nervous System Diseases D009422 37 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Heyman E et al. Intense exercise increases circulating endocannabinoid and BDNF levels in humans--possible implications for reward and depression. 2012 Psychoneuroendocrinology pmid:22029953
Izumi Y and Zorumski CF NMDA receptors, mGluR5, and endocannabinoids are involved in a cascade leading to hippocampal long-term depression. 2012 Neuropsychopharmacology pmid:21993209
Malinowska B et al. Triphasic blood pressure responses to cannabinoids: do we understand the mechanism? 2012 Br. J. Pharmacol. pmid:22022923
Marsicano G and Chaouloff F Moving bliss: a new anandamide transporter. 2012 Nat. Neurosci. pmid:22193249
Battista N et al. Abnormal anandamide metabolism in celiac disease. 2012 J. Nutr. Biochem. pmid:22209002
Schulte K et al. Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor. 2012 Naunyn Schmiedebergs Arch. Pharmacol. pmid:22215206
Wu X et al. Alteration of endocannabinoid system in human gliomas. 2012 J. Neurochem. pmid:22176552
Chianese R et al. Anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22669247
Chicca A et al. The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors. 2012 Br. J. Pharmacol. pmid:22646533
Hernangómez M et al. CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation. 2012 Glia pmid:22653796
Tsumura M et al. TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts. 2012 Cell Calcium pmid:22656960
Méndez-Díaz M et al. The endocannabinoid system modulates the valence of the emotion associated to food ingestion. 2012 Addict Biol pmid:21182571
Berger WT et al. Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. 2012 PLoS ONE pmid:23236415
Roa-Coria JE et al. N-(4-Methoxy-2-nitrophenyl)hexadecanamide, a palmitoylethanolamide analogue, reduces formalin-induced nociception. 2012 Life Sci. pmid:23069585
Schmidt W et al. Cannabinoid receptor subtypes 1 and 2 mediate long-lasting neuroprotection and improve motor behavior deficits after transient focal cerebral ischemia. 2012 Neuroscience pmid:23069763
Pastuhov SI et al. Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling. 2012 Nat Commun pmid:23072806
Fu J et al. A catalytically silent FAAH-1 variant drives anandamide transport in neurons. 2012 Nat. Neurosci. pmid:22101642
Feuerecker M et al. Effects of exercise stress on the endocannabinoid system in humans under field conditions. 2012 Eur. J. Appl. Physiol. pmid:22101870
Reyes-Cabello C et al. Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration. 2012 Pharmacol. Biochem. Behav. pmid:22133635
Feuerecker M et al. Effect of an acute consumption of a moderate amount of ethanol on plasma endocannabinoid levels in humans. 2012 May-Jun Alcohol Alcohol. pmid:22278319
Camann DE et al. Acetaminophen, pesticide, and diethylhexyl phthalate metabolites, anandamide, and fatty acids in deciduous molars: potential biomarkers of perinatal exposure. 2013 J Expo Sci Environ Epidemiol pmid:22805989
Chiou LC et al. Targeting the cannabinoid system for pain relief? 2013 Acta Anaesthesiol Taiwan pmid:24529672
Fowler CJ Transport of endocannabinoids across the plasma membrane and within the cell. 2013 FEBS J. pmid:23441874
Chiurchiù V et al. Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis. 2013 Ann. Neurol. pmid:23447381
Romano MR and Lograno MD Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle. 2013 Eur. J. Pharmacol. pmid:23396229
Romero TR et al. CB1 and CB2 cannabinoid receptor agonists induce peripheral antinociception by activation of the endogenous noradrenergic system. 2013 Anesth. Analg. pmid:23302980
Ho WS Modulation by 17β-estradiol of anandamide vasorelaxation in normotensive and hypertensive rats: a role for TRPV1 but not fatty acid amide hydrolase. 2013 Eur. J. Pharmacol. pmid:23340220
Zhuang J et al. The interaction of fatty acid amide hydrolase (FAAH) inhibitors with an anandamide carrier protein using (19)F-NMR. 2013 AAPS J pmid:23344792
Avraham Y et al. Novel acylethanolamide derivatives that modulate body weight through enhancement of hypothalamic pro-opiomelanocortin (POMC) and/or decreased neuropeptide Y (NPY). 2013 J. Med. Chem. pmid:23384387
Gebeh AK et al. Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity. 2013 J. Clin. Endocrinol. Metab. pmid:23372171
Compagnucci C et al. Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells. 2013 PLoS ONE pmid:23372698
Brown I et al. Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators. 2013 Prog. Lipid Res. pmid:23103355
Starowicz K et al. Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. 2013 PLoS ONE pmid:23573230
Subbanna S et al. Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits. 2013 J. Neurosci. pmid:23575834
Descalzi F et al. Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism. 2013 Tissue Eng Part A pmid:23578218
Morgan CJ et al. Cerebrospinal fluid anandamide levels, cannabis use and psychotic-like symptoms. 2013 Br J Psychiatry pmid:23580381
Blankman JL and Cravatt BF Chemical probes of endocannabinoid metabolism. 2013 Pharmacol. Rev. pmid:23512546
Seillier A et al. Phencyclidine-induced social withdrawal results from deficient stimulation of cannabinoid CB₁ receptors: implications for schizophrenia. 2013 Neuropsychopharmacology pmid:23563893
Hawkins V and Butt A TASK-1 channels in oligodendrocytes: a role in ischemia mediated disruption. 2013 Neurobiol. Dis. pmid:23567653
Bilmin K et al. Influence of serum and albumin on the in vitro anandamide cytotoxicity toward C6 glioma cells assessed by the MTT cell viability assay: implications for the methodology of the MTT tests. 2013 Folia Neuropathol pmid:23553136
Haller J et al. The effects of anandamide signaling enhanced by the FAAH inhibitor URB597 on coping styles in rats. 2013 Psychopharmacology (Berl.) pmid:23743650
Wenzel D et al. Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:24167249
Li H et al. Inhibition of fatty acid amide hydrolase activates Nrf2 signalling and induces heme oxygenase 1 transcription in breast cancer cells. 2013 Br. J. Pharmacol. pmid:23347118
Maione S et al. Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics. 2013 Pharmacol. Res. pmid:23911581
Jourdan T et al. Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes. 2013 Nat. Med. pmid:23955712
O'Brien LD et al. Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus). 2013 Br. J. Pharmacol. pmid:23991698
Malenczyk K et al. CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release. 2013 J. Biol. Chem. pmid:24089517
Brocato B et al. Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity. 2013 Placenta pmid:24008071
Gunduz-Cinar O et al. Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity. 2013 Mol. Psychiatry pmid:22688188
Stanley CP et al. Cannabinoids alter endothelial function in the Zucker rat model of type 2 diabetes. 2013 Eur. J. Pharmacol. pmid:24120371