| MeSH term | MeSH ID | Detail |
|---|---|---|
| Migraine Disorders | D008881 | 11 associated lipids |
| Morphine Dependence | D009021 | 9 associated lipids |
| Multiple Sclerosis | D009103 | 13 associated lipids |
| Muscle Spasticity | D009128 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Neoplasm Invasiveness | D009361 | 23 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Andrianova EL et al. | In vitro effects of anandamide and prostamide e2 on normal and transformed nerve cells. | 2011 | Bull. Exp. Biol. Med. | pmid:22442796 |
| Weller K et al. | TRPV1, TRPA1, and CB1 in the isolated vagus nerve--axonal chemosensitivity and control of neuropeptide release. | 2011 | Neuropeptides | pmid:21868092 |
| Aberturas MR et al. | Anandamide-loaded nanoparticles: preparation and characterization. | 2011 | J Microencapsul | pmid:21425945 |
| Pinar-Sueiro S et al. | [Cannabinoid applications in glaucoma]. | 2011 | Arch Soc Esp Oftalmol | pmid:21414525 |
| Mukhopadhyay B et al. | Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21383171 |
| Rossi S et al. | Cannabinoid CB1 receptors regulate neuronal TNF-α effects in experimental autoimmune encephalomyelitis. | 2011 | Brain Behav. Immun. | pmid:21473912 |
| Gamaleddin I et al. | The selective anandamide transport inhibitor VDM11 attenuates reinstatement of nicotine seeking behaviour, but does not affect nicotine intake. | 2011 | Br. J. Pharmacol. | pmid:21501143 |
| Di Marzo V | Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight. | 2011 | Nat. Neurosci. | pmid:21187849 |
| Bari M et al. | The manifold actions of endocannabinoids on female and male reproductive events. | 2011 | Front Biosci (Landmark Ed) | pmid:21196184 |
| Guindon J et al. | Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. | 2011 | Br. J. Pharmacol. | pmid:21198549 |
| Liao YS et al. | [Anandamide inhibits the growth of colorectal cancer cells through CB1 and lipid rafts]. | 2011 | Zhonghua Zhong Liu Za Zhi | pmid:21575494 |
| Shekhar C | Mixed signals: cannabinoid system offers new therapeutic possibilities as well as challenges. | 2011 | Chem. Biol. | pmid:21609833 |
| Hutchins HL et al. | Eicosapentaenoic acid decreases expression of anandamide synthesis enzyme and cannabinoid receptor 2 in osteoblast-like cells. | 2011 | J. Nutr. Biochem. | pmid:20951563 |
| Mestre L et al. | Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB(1) receptors. | 2011 | J Neuroinflammation | pmid:21851608 |
| Feledziak M et al. | SAR and LC/MS studies of β-lactamic inhibitors of human fatty acid amide hydrolase (hFAAH): evidence of a nonhydrolytic process. | 2011 | J. Med. Chem. | pmid:21899370 |
| Palermo G et al. | Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas. | 2011 | J. Med. Chem. | pmid:21830831 |
| Johannesson M et al. | Cloning, purification and characterization of non-human primate 12/15-lipoxygenases. | 2010 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20106647 |
| Davies JW et al. | Pharmacology of capsaicin-, anandamide-, and N-arachidonoyl-dopamine-evoked cell death in a homogeneous transient receptor potential vanilloid subtype 1 receptor population. | 2010 | Br J Anaesth | pmid:20354008 |
| Greco R et al. | Alterations of the endocannabinoid system in an animal model of migraine: evaluation in cerebral areas of rat. | 2010 | Cephalalgia | pmid:19515121 |
| Correa F et al. | Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB. | 2010 | Glia | pmid:19565660 |
| Amorós I et al. | Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner. | 2010 | J. Mol. Cell. Cardiol. | pmid:19616555 |
| Falenski KW et al. | FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration. | 2010 | Neuropsychopharmacology | pmid:20357755 |
| Wu WJ et al. | [Membrane cholesterol mediates the endocannabinoids-anandamide affection on HepG2 cells]. | 2010 | Zhonghua Gan Zang Bing Za Zhi | pmid:20380798 |
| Hoot MR et al. | Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice. | 2010 | Brain Res. | pmid:20380816 |
| Fisar Z | Inhibition of monoamine oxidase activity by cannabinoids. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20401651 |
| Nallendran V et al. | The plasma levels of the endocannabinoid, anandamide, increase with the induction of labour. | 2010 | BJOG | pmid:20406230 |
| Kobayashi N and Yamamoto Y | Hypoxic responses of arterial chemoreceptors in rabbits are primarily mediated by leak K channels. | 2010 | Adv. Exp. Med. Biol. | pmid:20217348 |
| Roser P et al. | Potential antipsychotic properties of central cannabinoid (CB1) receptor antagonists. | 2010 | World J. Biol. Psychiatry | pmid:20218784 |
| Musella A et al. | Transient receptor potential vanilloid 1 channels control acetylcholine/2-arachidonoylglicerol coupling in the striatum. | 2010 | Neuroscience | pmid:20219639 |
| Caraceni P et al. | Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. | 2010 | Liver Int. | pmid:19840245 |
| Pratt-Hyatt M et al. | Effects of a commonly occurring genetic polymorphism of human CYP3A4 (I118V) on the metabolism of anandamide. | 2010 | Drug Metab. Dispos. | pmid:20702771 |
| Buznikov GA et al. | A putative 'pre-nervous' endocannabinoid system in early echinoderm development. | 2010 | Dev. Neurosci. | pmid:19907129 |
| Sagar DR et al. | Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. | 2010 | Arthritis Rheum. | pmid:20722027 |
| Kaczocha M et al. | Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2. | 2010 | J. Biol. Chem. | pmid:19926788 |
| Jiang S et al. | Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment. | 2010 | J. Biol. Chem. | pmid:20826813 |
| Linsalata M et al. | Effects of anandamide on polyamine levels and cell growth in human colon cancer cells. | 2010 | Anticancer Res. | pmid:20682986 |
| Aquila S et al. | Human sperm anatomy: ultrastructural localization of the cannabinoid1 receptor and a potential role of anandamide in sperm survival and acrosome reaction. | 2010 | Anat Rec (Hoboken) | pmid:19938110 |
| Osman NA et al. | Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands. | 2010 | Bioorg. Med. Chem. | pmid:21074998 |
| Wiley JL and Burston JJ | Chronic Delta9-tetrahydrocannabinol during adolescence increases sensitivity to subsequent cannabinoid effects in delayed nonmatch-to-position in rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:19941884 |
| Piccinetti CC et al. | Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish. | 2010 | Gen. Comp. Endocrinol. | pmid:19800340 |
| Catani MV et al. | Anandamide extends platelets survival through CB(1)-dependent Akt signaling. | 2010 | Cell. Mol. Life Sci. | pmid:19936621 |
| Xie S et al. | Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2. | 2010 | Chem. Res. Toxicol. | pmid:21049984 |
| Banni S and Di Marzo V | Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. | 2010 | Mol Nutr Food Res | pmid:20013888 |
| Amoako AA et al. | Quantitative analysis of anandamide and related acylethanolamides in human seminal plasma by ultra performance liquid chromatography tandem mass spectrometry. | 2010 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21056015 |
| Godlewski G et al. | Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects. | 2010 | Chem. Biol. | pmid:21095576 |
| Ziegler CG et al. | Expression and function of endocannabinoid receptors in the human adrenal cortex. | 2010 | Horm. Metab. Res. | pmid:19862666 |
| Herrera-SolÃs A et al. | Acute and subchronic administration of anandamide or oleamide increases REM sleep in rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:20056119 |
| Malinowska B et al. | Involvement of central beta2-adrenergic, NMDA and thromboxane A2 receptors in the pressor effect of anandamide in rats. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20198363 |
| Romigi A et al. | Cerebrospinal fluid levels of the endocannabinoid anandamide are reduced in patients with untreated newly diagnosed temporal lobe epilepsy. | 2010 | Epilepsia | pmid:19817812 |
| Di Marzo V | Anandamide serves two masters in the brain. | 2010 | Nat. Neurosci. | pmid:21102567 |
| Zakrzeska A et al. | A cannabinoid receptor, sensitive to O-1918, is involved in the delayed hypotension induced by anandamide in anaesthetized rats. | 2010 | Br. J. Pharmacol. | pmid:20105178 |
| Bardell TK and Barker EL | Activation of TRPC6 channels promotes endocannabinoid biosynthesis in neuronal CAD cells. | 2010 | Neurochem. Int. | pmid:20466028 |
| Naccarato M et al. | Possible Anandamide and Palmitoylethanolamide involvement in human stroke. | 2010 | Lipids Health Dis | pmid:20470384 |
| Muccioli GG | Endocannabinoid biosynthesis and inactivation, from simple to complex. | 2010 | Drug Discov. Today | pmid:20304091 |
| Laezza C et al. | Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and of Ras farnesylation mediate antitumor effects of anandamide in human breast cancer cells. | 2010 | Endocr. Relat. Cancer | pmid:20304978 |
| Makwana R et al. | Pharmacological characterization of cannabinoid receptor activity in the rat-isolated ileum myenteric plexus-longitudinal muscle preparation. | 2010 | Br. J. Pharmacol. | pmid:20233228 |
| Kozono S et al. | Involvement of the endocannabinoid system in periodontal healing. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20233580 |
| Yang YY et al. | Mechanisms of TNFalpha-induced cardiac dysfunction in cholestatic bile duct-ligated mice: interaction between TNFalpha and endocannabinoids. | 2010 | J. Hepatol. | pmid:20626112 |
| Lisboa SF et al. | Cannabinoid CB1 receptors in the medial prefrontal cortex modulate the expression of contextual fear conditioning. | 2010 | Int. J. Neuropsychopharmacol. | pmid:20587131 |
| Thors L et al. | Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase. | 2010 | Br. J. Pharmacol. | pmid:20590565 |
| Mukhopadhyay P et al. | CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model. | 2010 | Br. J. Pharmacol. | pmid:20590569 |
| Rajesh M et al. | Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells. | 2010 | Br. J. Pharmacol. | pmid:20590572 |
| Wheal AJ et al. | Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity. | 2010 | Br. J. Pharmacol. | pmid:20590573 |
| Gutierrez-Lopez MD et al. | Involvement of 2-arachidonoyl glycerol in the increased consumption of and preference for ethanol of mice treated with neurotoxic doses of methamphetamine. | 2010 | Br. J. Pharmacol. | pmid:20590579 |
| Soneji ND et al. | Effects of cannabinoids on capsaicin receptor activity following exposure of primary sensory neurons to inflammatory mediators. | 2010 | Life Sci. | pmid:20598325 |
| Patsos HA et al. | The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells. | 2010 | Int. J. Oncol. | pmid:20514410 |
| Maccarrone M et al. | Intracellular trafficking of anandamide: new concepts for signaling. | 2010 | Trends Biochem. Sci. | pmid:20570522 |
| Fernandez-Solari J et al. | Participation of the endocannabinoid system in lipopolysaccharide-induced inhibition of salivary secretion. | 2010 | Arch. Oral Biol. | pmid:20542488 |
| Bhaskaran MD and Smith BN | Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy. | 2010 | PLoS ONE | pmid:20498848 |
| Lam PM et al. | Simultaneous measurement of three N-acylethanolamides in human bio-matrices using ultra performance liquid chromatography-tandem mass spectrometry. | 2010 | Anal Bioanal Chem | pmid:20835819 |
| Sántha P et al. | The endogenous cannabinoid anandamide inhibits transient receptor potential vanilloid type 1 receptor-mediated currents in rat cultured primary sensory neurons. | 2010 | Acta Physiol Hung | pmid:20511124 |
| Talevi R et al. | Is there a role for endocannabinoids in sperm-oviduct interaction? | 2010 | Reproduction | pmid:20511399 |
| Muccioli GG et al. | The endocannabinoid system links gut microbiota to adipogenesis. | 2010 | Mol. Syst. Biol. | pmid:20664638 |
| Suárez J et al. | Endocannabinoid system in the adult rat circumventricular areas: an immunohistochemical study. | 2010 | J. Comp. Neurol. | pmid:20533360 |
| Clapper JR et al. | Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism. | 2010 | Nat. Neurosci. | pmid:20852626 |
| Jenkin KA et al. | Role for cannabinoid receptors in human proximal tubular hypertrophy. | 2010 | Cell. Physiol. Biochem. | pmid:21220919 |
| Onnis V et al. | Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors. | 2010 | J. Med. Chem. | pmid:20143779 |
| Bhaskaran MD and Smith BN | Effects of TRPV1 activation on synaptic excitation in the dentate gyrus of a mouse model of temporal lobe epilepsy. | 2010 | Exp. Neurol. | pmid:20144892 |
| Alptekin A et al. | The effects of anandamide transport inhibitor AM404 on voltage-dependent calcium channels. | 2010 | Eur. J. Pharmacol. | pmid:20171208 |
| Snider NT et al. | Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by the cytochrome P450 monooxygenases: physiological and pharmacological implications. | 2010 | Pharmacol. Rev. | pmid:20133390 |
| Moreno-Galindo EG et al. | Molecular basis for a high-potency open-channel block of Kv1.5 channel by the endocannabinoid anandamide. | 2010 | Mol. Pharmacol. | pmid:20133392 |
| Weis F et al. | Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. | 2010 | J. Mol. Cell. Cardiol. | pmid:19931541 |
| Ribeiro A et al. | Anandamide prior to sensitization increases cell-mediated immunity in mice. | 2010 | Int. Immunopharmacol. | pmid:20093200 |
| Cencioni MT et al. | Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors. | 2010 | PLoS ONE | pmid:20098669 |
| Pamplona FA et al. | Aspirin-triggered lipoxin induces CB1-dependent catalepsy in mice. | 2010 | Neurosci. Lett. | pmid:20036315 |
| Oz M et al. | The endogenous cannabinoid, anandamide, inhibits dopamine transporter function by a receptor-independent mechanism. | 2010 | J. Neurochem. | pmid:20050977 |
| Yang Q et al. | Anandamide induces cell death through lipid rafts in hepatic stellate cells. | 2010 | J. Gastroenterol. Hepatol. | pmid:20059638 |
| Sang N et al. | Anandamide potentiation of miniature spontaneous excitatory synaptic transmission is mediated via IP3 pathway. | 2010 | Neurochem. Int. | pmid:20064571 |
| Aquila S et al. | Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm. | 2010 | Br. J. Pharmacol. | pmid:20067470 |
| Marczylo TH et al. | Anandamide levels in human female reproductive tissues: solid-phase extraction and measurement by ultraperformance liquid chromatography tandem mass spectrometry. | 2010 | Anal. Biochem. | pmid:20026294 |
| Touriño C et al. | FAAH deficiency promotes energy storage and enhances the motivation for food. | 2010 | Int J Obes (Lond) | pmid:20029375 |
| Yoshida R et al. | Endocannabinoids selectively enhance sweet taste. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20080779 |
| Ligresti A et al. | Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter. | 2010 | PLoS ONE | pmid:20422025 |
| Annuzzi G et al. | Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients. | 2010 | Lipids Health Dis | pmid:20426869 |
| El-Talatini MR et al. | The relationship between plasma levels of the endocannabinoid, anandamide, sex steroids, and gonadotrophins during the menstrual cycle. | 2010 | Fertil. Steril. | pmid:19200965 |
| Cozzolino R et al. | A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis. | 2010 | Invest New Drugs | pmid:19189054 |
| Mukhopadhyay P et al. | CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes. | 2010 | Cardiovasc. Res. | pmid:19942623 |
| Barana A et al. | Endocannabinoids and cannabinoid analogues block cardiac hKv1.5 channels in a cannabinoid receptor-independent manner. | 2010 | Cardiovasc. Res. | pmid:19689982 |
| Gratzke C et al. | Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. | 2010 | Eur. Urol. | pmid:19147270 |
| Prieto D | Editorial comment on: localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. | 2010 | Eur. Urol. | pmid:19147273 |