Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Overweight D050177 11 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Orthostatic Intolerance D054971 1 associated lipids
Vascular System Injuries D057772 2 associated lipids
Acute Pain D059787 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
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Ohsaka Y and Nishino H 3T3-L1 adipocytes possess anandamide- and epinephrine-responsive machinery for MDM2 distribution to the plasma membrane. 2013 Gen. Physiol. Biophys. pmid:23682023
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Li Q et al. Anandamide reduces intracellular Ca2+ concentration through suppression of Na+/Ca2+ exchanger current in rat cardiac myocytes. 2013 PLoS ONE pmid:23667607
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Lenglet S et al. Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice. 2013 Arterioscler. Thromb. Vasc. Biol. pmid:23241405
Silva GB et al. Anandamide inhibits transport-related oxygen consumption in the loop of Henle by activating CB1 receptors. 2013 Am. J. Physiol. Renal Physiol. pmid:23220721
Citraro R et al. Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy. 2013 Neuropharmacology pmid:23206503
Dékány A et al. The contractile effect of anandamide in the guinea-pig small intestine is mediated by prostanoids but not TRPV1 receptors or capsaicin-sensitive nerves. 2013 Basic Clin. Pharmacol. Toxicol. pmid:23216932
Lee TT et al. Temporal changes in N-acylethanolamine content and metabolism throughout the peri-adolescent period. 2013 Synapse pmid:22987804
Han B et al. Quantitative LC-MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor. 2013 Anal. Biochem. pmid:23044255
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Li Q et al. Anandamide enhances expression of heat shock protein 72 to protect against ischemia-reperfusion injury in rat heart. 2013 J Physiol Sci pmid:23007622
Rivera P et al. Diet-dependent modulation of hippocampal expression of endocannabinoid signaling-related proteins in cannabinoid antagonist-treated obese rats. 2013 Eur. J. Neurosci. pmid:23033907
Derbenev AV and Smith BN Dexamethasone rapidly increases GABA release in the dorsal motor nucleus of the vagus via retrograde messenger-mediated enhancement of TRPV1 activity. 2013 PLoS ONE pmid:23936221
Krumbholz A et al. Diagnostic value of concentration profiles of glucocorticosteroids and endocannabinoids in hair. 2013 Ther Drug Monit pmid:23942543
Liu J et al. Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:24191036
Hill MN et al. Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks. 2013 Psychoneuroendocrinology pmid:24035186
Marichal-Cancino BA et al. Analysis of anandamide- and lysophosphatidylinositol-induced inhibition of the vasopressor responses produced by sympathetic stimulation or noradrenaline in pithed rats. 2013 Eur. J. Pharmacol. pmid:24076186
Akerman S et al. Endocannabinoids in the brainstem modulate dural trigeminovascular nociceptive traffic via CB1 and "triptan" receptors: implications in migraine. 2013 J. Neurosci. pmid:24027286
Adinolfi B et al. Anticancer activity of anandamide in human cutaneous melanoma cells. 2013 Eur. J. Pharmacol. pmid:24041928
Fonseca BM et al. The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation. 2013 Apoptosis pmid:24048885
Khlaifia A et al. Anandamide, cannabinoid type 1 receptor, and NMDA receptor activation mediate non-Hebbian presynaptically expressed long-term depression at the first central synapse for visceral afferent fibers. 2013 J. Neurosci. pmid:23904599
Citraro R et al. CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations. 2013 Epilepsy Res. pmid:23860329
Bernabò N et al. Systems biology analysis of the endocannabinoid system reveals a scale-free network with distinct roles for anandamide and 2-arachidonoylglycerol. 2013 OMICS pmid:24117401
Vavilin VA et al. Cytochrome P450 4F2 polymorphism in patients with liver cirrhosis. 2013 Bull. Exp. Biol. Med. pmid:24319743
Leung K et al. Role of FAAH-like anandamide transporter in anandamide inactivation. 2013 PLoS ONE pmid:24223930